• I 2 and TBHP mediate a convenient synthesis of 2-acylbenzothiazoles in very good yields from acetophenones and benzothiazoles. (organic-chemistry.org)
  • Zhi-Bing Dong describes an iodobenzene-promoted palladium-catalyzed synthesis of benzothiazoles via intramolecular coupling. (thieme.de)
  • Herein, the formation of a photosensitizing disulfide in benzothiazole synthesis from 2-Aminothiophenol and aldehydes was proposed and confirmed through in-depth mechanistic studies. (ewha.ac.kr)
  • Although the parent compound, benzothiazole is not widely used, many of its derivatives are found in commercial products or in nature. (wikipedia.org)
  • A series of novel 2- substituted benzothiazole dithiomidocarbonate derivatives were synthesized by the reaction of 2-amino benzothiazole with various halides. (ijpsr.com)
  • One such prominent heterocyclic system is benzothiazole with several of its derivatives exhibiting diversified biological activity. (ijpsr.com)
  • Members of the benzothiazole aniline (BTA) family of compounds are characterized as a class of small molecules that have shown great promise in preventing Aβ-protein interactions. (jneurosci.org)
  • Benzothiazole moieties are part of compounds showing numerous biological activities such as antimicrobial, anticancer, antihelminthic, anti-diabetic activities etc. (ijpsr.com)
  • Researchers at Ningbo Combireg Pharmaceutical Technology Co. Ltd. and Versitech Ltd. have described benzothiazole compounds reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19). (bioworld.com)
  • Benzothiazole is an aromatic heterocyclic compound with the chemical formula C 7H 5NS. (wikipedia.org)
  • 1-8 Benzothiazole is one of the most important heterocyclic compound, weak base, having varied biological activity they are widely found in bioorganic and medicinal chemistry with application in drug discovery. (ijpsr.com)
  • Firefly luciferin can be considered a derivative of benzothiazole. (wikipedia.org)
  • A benzothiazole derivative is suggested as a dye for arsenic detection. (wikipedia.org)
  • The tetra(ethylene glycol) derivative of benzothiazole aniline, BTA-EG 4 , is a novel amyloid-binding small molecule that can penetrate the blood-brain barrier and protect cells from Aβ-induced toxicity. (jneurosci.org)
  • Riluzole is in a class of medications called benzothiazoles. (medlineplus.gov)
  • Riluzole, a benzothiazole compound, is the only drug approved by the US Food and Drug Administration (FDA) for the treatment of amyotrophic lateral sclerosis. (lookchem.com)
  • Benzothiazoles consist of a 5-membered 1,3-thiazole ring fused to a benzene ring. (wikipedia.org)
  • Benzothiazole consists of a 5-membered 1,3thiazole ring fused to a benzene ring. (ijpsr.com)
  • Benzothiazoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (jefferson.edu)
  • Benzothiazoles are prepared by treatment of 2-mercaptoaniline with acid chlorides: C6H4(NH2)SH + RC(O)Cl → C6H4(NH)SCR + HCl + H2O Benzothiazole occurs naturally in some foods but is also used as a food additive. (wikipedia.org)
  • This graph shows the total number of publications written about "Benzothiazoles" by people in this website by year, and whether "Benzothiazoles" was a major or minor topic of these publications. (jefferson.edu)
  • This value indicates that benzothiazole will volatilize slowly from water surfaces(2,SRC). (charite.de)
  • Below are the most recent publications written about "Benzothiazoles" by people in Profiles. (jefferson.edu)
  • Various benzothiazoles such as 2-substituted benzothiazole received much attention due to unique structure and its uses as radioactive amyloidal imaging agents, and anticancer agents. (ijpsr.com)
  • The formal acylation of the benzothiazoles is achieved through a sequence involving formation of an aryl glyoxal, ring-opening of the benzothiazole followed by condensation of the amino group with the aryl glyoxal, cyclization and oxidation. (organic-chemistry.org)
  • We identified an amino-benzothiazole scaffold from a whole-cell screen against recombinant Mycobacterium tuberculosis under expressing the essential signal peptidase LepB. (nih.gov)
  • Therefore, the researchers modified the amyloid dye thioflavin-T by extending the backbone, leading to a class of five phenyl/pyridinyl-butadienyl-benzothiazoles/benzothiazoliums-PBBs-that they examined further in brain slices. (alzforum.org)
  • Benzothiazole is an aromatic heterocyclic compound with the chemical formula C 7H 5NS. (wikipedia.org)
  • Riluzole is in a class of medications called benzothiazoles. (medlineplus.gov)
  • An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Benzothiazole (95-16-9). (nih.gov)
  • Detector sensitivity provided quantitation in the sub-microgram benzothiazole was determined during the same analysis run, this method is straightforward and analytically efficient. (cdc.gov)