AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentInformation Science
Pleural EffusionPleural Effusion, MalignantPericardial EffusionTuberculosis, PleuralExudates and TransudatesPleuraPleurodesisPleural CavityOtitis Media with EffusionHydrothoraxTalcChylothoraxParacentesisEmpyema, PleuralPleural DiseasesDrainagePleurisyPleural NeoplasmsEmpyemaThoracoscopyThoracostomyMesotheliomaAscitesChest TubesRadiography, ThoracicLymphoma, Primary EffusionLung NeoplasmsPicibanilEmpyema, TuberculousMeigs SyndromePneumothoraxEncyclopedias as TopicAsbestosis
TumorsTumorDiseasesChestMesothelioma2023ExudativeSensitivity and specifiMalignancyNeoplasmsUnilateral pleuralPulmonaryPeritonealEmpyemaDiagnosticCause of pleural effusionThoracicAsbestos-relatedCongestive heart fCytologyPatientsCathetersParapneumonic effusionsVolume of pleural fluidPneumothoraxCauses of pleuralComplicationsLesionsFibromaTransudativeAbstractMesothelialDifferentiationBloody pleuralPleuraPleurodesisPericardial effusionFindingsLarge pleuralOccurCavityCarcinomasInterstitialEtiologyConclusionsLung and pleuralClinicalSynovial sarcomaBuildup of fluid
Tumors29
  • Exudative pleural effusion results from infections, inflammation, or tumors. (mesothelioma.net)
  • One third of all ovarian tumors are serous, and two thirds of these serous tumors are benign. (medscape.com)
  • Of these tumors, 75% are benign and are found in women aged 30-50 years. (medscape.com)
  • citation needed] Pleural tumors may be benign (i.e. solitary fibrous tumor) or malignant in nature. (wikipedia.org)
  • Mesothelial tumors: pleural malignant mesothelioma. (wikipedia.org)
  • This condition is commonly caused by acquiring an infection, inflammatory diseases, and malignant (cancerous) tumors. (medicalnewstoday.com)
  • Either cancerous or benign (non-cancerous) tumors can put pressure on airways and lung tissues, potentially causing them to collapse. (medicalnewstoday.com)
  • A comparison of the intrathoracic malignant neurogenic tumors and the benign neurogenic tumors resected at our institution revealed no meaningful differences distinguishing malignant from benign neurogenic tumors prior to surgery. (springeropen.com)
  • Additionally, we present a comparison of the clinical characteristics and outcomes of these patients and those of patients with benign neurogenic tumors (BNTs) resected at our institution. (springeropen.com)
  • Gastric schwannoma represent only 0.2% of all gastric tumors and 4% of all benign gastric neoplasms. (sages.org)
  • Gastric schwannomas are often misdiagnosed as malignant gastrointestinal stromal tumors (GIST) following EGD, EUS and PET/CT (Positron emission tomographic/computed tomographic) imaging. (sages.org)
  • INTRODUCTION: The distinction between benign and borderline epithelial ovarian tumors is important because treatment and follow-up strategies differ OBJECTIVE: We aimed to evaluate benign, borderline, and malignant epithelial ovarian tumors using MRI features and contributed to the preoperative evaluation. (bvsalud.org)
  • CONCLUSION: The differentiation of borderline tumors from benign and malignant tumors by MRI scoring will contribute to the preoperative diagnosis. (bvsalud.org)
  • Background: Primary cardiac tumors are considerably less common than secondary cardiac malignant tumors. (itmedicalteam.pl)
  • Lipomas are rare primary cardiac tumors that account for 8.4% of benign primary cardiac tumors. (itmedicalteam.pl)
  • Similar to other epithelial ovarian tumors, Benner tumors are classified as benign, borderline/atypical proliferative, or malignant. (cap.org)
  • Benign Brenner tumors account for approximately 5% of all benign ovarian epithelial tumors and are typically found incidentally in women in the 5th to 7th decades of life. (cap.org)
  • Grossly, benign Brenner tumors are small (typically less than 2 cm) and unilateral. (cap.org)
  • Small cysts are often present, but benign Brenner tumors are rarely predominantly cystic. (cap.org)
  • Borderline/atypical proliferative Brenner tumors are often larger than benign Brenner tumors, with an average diameter of 18 cm. (cap.org)
  • These tumors are predominantly cystic but may contain variable solid areas, often representing a coexisting benign Brenner component. (cap.org)
  • Malignant Brenner tumors are uncommon ovarian carcinomas and represent less than 5% of all Brenner tumors. (cap.org)
  • Most tumors are confined to the ovary at diagnosis, and malignant Brenner tumors have a better prognosis than other epithelial ovarian carcinomas. (cap.org)
  • Histologically, malignant Brenner tumors are associated with a benign or borderline/atypical proliferative Brenner tumor component. (cap.org)
  • Using a mouse monoclonal antibody (L523S) against KOC, KOC expression was investigated in malignant tumors and reactive mesothelial cells in serous effusions. (mesothelioma-line.com)
  • The differential diagnosis of intracavitary mass lesions includes benign, malignant primary, secondary metastatic cardiac tumors, or thrombus. (medscape.com)
  • Benign lung tumors. (medlineplus.gov)
  • Description Pseudo-pseudo Meigs Syndrome (PPMS) or Tjalma Syndrome is characterized by ascites, pleural effusion, increased CA-125 marker, and a diagnosis of Systemic Lupus Erythematosus (SLE) with no evidence of any gynecologic tumors. (bmj.com)
  • It is a rare diagnosis of exclusion from Meigs syndrome and Pseudo-Meigs syndrome which are associated with benign and malignant tumors respectively. (bmj.com)
Tumor21
  • In the absence of mediastinal shift, the differential diagnosis is narrowed to carcinoma of the ipsilateral mainstem bronchus with or without ipsilateral lung atelectasis, fixed mediastinum caused by fibrosis or tumor infiltration of the mediastinal lymph nodes, tumor infiltration of the ipsilateral lung, malignant mesothelioma, or complete atelectasis of the ipsilateral lung. (medscape.com)
  • A 2-year interim analysis from the International Ovarian Tumor Analysis Phase 5 (IOTA5) study showed that 80% of ovarian cysts considered benign on ultrasonography either disappeared or required no intervention. (medscape.com)
  • Several tumor markers have been evaluated in pleural fluid, but their clinical role has not been firmly established. (nih.gov)
  • The aim of this study is to determine the diagnostic value of carbohydrate antigen 549 (CA 549) levels in pleural fluid, and to compare it with another previously studied tumor markers: carcinoembryonic antigen (CEA), CA 15.3 and CA 72.4. (nih.gov)
  • The best combination of tumor markers for differentiating malignant from benign effusions was CA 549+CEA+CA 15.3, with a sensitivity of 0.65, specificity of 0.99 and accuracy of 0.85. (nih.gov)
  • Individual tumor markers or their combination increased the sensitivity of pleural cytology. (nih.gov)
  • Moreover, the fibrous nature of the tumor has given rise to various other names, such as pleural fibroma, submesothelial fibroma, and localized fibrous tumor. (medscape.com)
  • Diagnosis of malignant pleural effusion with combinations of multiple tumor markers: A comparison study of five machine learning models. (cdc.gov)
  • Deep learning-based segmentation of malignant pleural mesothelioma tumor on computed tomography scans: application to scans demonstrating pleural effusion. (cdc.gov)
  • We present three patients with intrathoracic malignant neurogenic tumor. (springeropen.com)
  • Because there is no effective chemotherapeutic regimen for intrathoracic malignant neurogenic tumor, all three patients received high-dose chemotherapy followed by hematopoietic stem cell transplantation. (springeropen.com)
  • Among these cases, malignant neurogenic tumor (MNT) of the thorax is rare. (springeropen.com)
  • Mesothelioma, a malignant tumor of the pleura and/or peritoneum, is characterized by a long latency (time from exposure to disease onset), with a median of approximately 40 years. (msdmanuals.com)
  • CT examination was suggestive for a voluminous intrapericardial lipoma and a pleural malignant tumor. (itmedicalteam.pl)
  • This case first appeared as Performance Improvement Program in Surgical Pathology (PIP) 2020, Case 31, and is benign Brenner tumor in the ovary. (cap.org)
  • The findings are consistent with a benign Brenner tumor. (cap.org)
  • Nests are large and crowded and may show fusion, as a result of epithelial proliferation that exceeds what is seen in benign Brenner tumor. (cap.org)
  • A benign Brenner tumor component is often present in the background. (cap.org)
  • Interestingly, 3 of 16 cases exhibited various degrees of positivity for KOC, 2 of which were diagnosed as lung adenocarcinoma with a recurrence after tumor resection and 1 as malignant pleural mesothelioma. (mesothelioma-line.com)
  • Initially, elevated tumor markers and high serum uric acid and high serum lactic dehydrogenase levels were related to necrotic tumor-derived tissue, decompensated heart failure with pleural effusion and renal insufficiency. (medscape.com)
  • If the tumor found on the mesothelium is cancerous, it is known as malignant mesothelioma, if it is noncancerous it is benign mesothelioma. (martinsonandbeason.com)
Diseases18
  • Our highly skilled, board-certified physicians provide specialized care in advanced interventional pulmonology and general pulmonary treatment for complex airway conditions and disorders, and pleural diseases. (ajh.org)
  • We prospectively studied 252 patients with pleural effusion: 101 malignant (20 mesothelioma) and 151 of several benign diseases. (nih.gov)
  • More common diseases, such as benign asbestos-related pleural disease and metastatic adenocarcinoma , can look radiographically identical to mesothelioma. (medscape.com)
  • The radiographic findings of mesothelioma are nonspecific and are observed in other diseases, including metastatic carcinoma, lymphoma, and benign asbestos disease. (medscape.com)
  • IEFs can represent unsuspected important diseases or benign findings, carrying several ethical, medicolegal, and financial implications [ 4 ]. (hindawi.com)
  • These studies were conducted on the population of Libby, Montana, where mining, transportation, and processing of asbestos-contaminated vermiculite caused an increased risk of asbestos-related pleural and lung diseases. (medscape.com)
  • In: Pleural Diseases. (jptcp.com)
  • The program also provides comprehensive evaluation and treatment of large-airway diseases, including both malignant and benign central-airway obstruction and tracheobronchomalacia. (uclahealth.org)
  • To best meet patients' needs, the program includes distinct sub-programs in thoracic oncology, complex airway diseases and pleural diseases. (uclahealth.org)
  • Our team includes pulmonologists who have received specialized training and are board certified in interventional pulmonology and are experienced in managing patients with complex airway and pleural diseases. (lifespan.org)
  • Background Recurrent pleural effusion is a common cause of dyspnoea, cough and chest pain during the course of infectious pleurisy and non-malignant diseases like congestive heart failure (CHF) or liver cirrhosis with hepatic hydrothorax (HH). (bmj.com)
  • With regard to the chronic character of the underlying diseases, indwelling pleural catheters (IPC) are increasingly used, not only assuring immediate symptom relief but also potentially leading to pleurodesis without sclerosing agents. (bmj.com)
  • We perform both flexible and rigid pleuroscopy to diagnose and treat pleural diseases. (dignityhealth.org)
  • Exudative effusions result from diseases that alter the pleural surface and its permeability to protein. (manualofmedicine.com)
  • This article describes the radiographic and cross-sectional appearances of pleural diseases, which are commonly encountered in every day practice. (ox.ac.uk)
  • Mesothelioma is the most serious of a list of diseases - including lung cancer, pleural plaques, asbestosis, and others - linked with exposure to asbestos dust. (survivingmesothelioma.com)
  • Diseases related to inhalation of asbestos include mesothelioma, lung cancer, diffuse pleural thickening or fibrosis, asbestosis, benign pleural effusion, larynx or pharynx cancer, and gastrointestinal cancer. (coastmountainnews.com)
  • CC- RT-PCR analysis was applied to pleural effusion specimens from patients with benign or malignant lung diseases as well as to spontaneously voided urine samples from patients with benign or malignant urologic diseases. (elsevierpure.com)
Chest17
  • The pleural space plays an important role in respiration by coupling the movement of the chest wall with that of the lungs in two ways. (medscape.com)
  • Anteroposterior upright chest radiograph shows a massive left-sided pleural effusion with contralateral mediastinal shift. (medscape.com)
  • Left lateral decubitus chest radiograph shows fluid layering on the left side, which is not a loculated effusion. (medscape.com)
  • Emergency physicians may rapidly perform ultrasonography of the chest to evaluate patients with suspected pleural effusion. (medscape.com)
  • A spiral chest CT scan should be obtained for most patients with pleural effusion when the condition's etiology cannot be readily determined or when complicated pleural effusion (eg, empyema, malignancy) is suspected. (medscape.com)
  • Pleural effusion is a build-up of fluid between the two layers of the pleura, the thin tissue surrounding the lungs and chest cavity. (mesothelioma.net)
  • Pericardial effusion may cause similar symptoms, especially pain in the chest. (mesothelioma.net)
  • If you have been diagnosed with mesothelioma , a chest X-ray may be enough for your doctor to detect fluid in the pleural cavity . (mesothelioma.net)
  • 8. Manuel Porcel J, Vives M, Esquerda A, Ruiz A. Usefulness of the British Thoracic Society and the American College of Chest Physicians guidelines in predicting pleural drainage of non-purulent parapneumonic effusions. (jptcp.com)
  • Abnormal diagnostic images - those showing a pulmonary nodule, enlarged lymph nodes in the chest, or an accumulation of fluid, called pleural effusion - are some of the most common reasons patients seek care through the UCLA Interventional Pulmonology Program. (uclahealth.org)
  • Previously, first-line treatment for recurrent symptomatic malignant pleural effusion was chest drain insertion and talc pleurodesis, with indwelling pleural catheter insertion reserved for patients with trapped lung or failed talc pleurodesis. (ox.ac.uk)
  • Pleural thickening can cause shortness of breath and chest pain. (msdmanuals.com)
  • Probrain natriuretic peptide was 2304?pg/mL, and chest radiograph showed a globular cardiac silhouette and blunting of the costophrenic angles due to a small transudative pleural effusion containing benign mesothelial cells on cytological analysis. (lamblawoffice.com)
  • The presence of a pleural abnormality is usually suggested following a routine chest x-ray, with a number of imaging modalities available for further characterization. (ox.ac.uk)
  • Chest X-ray was consistent with left pleural effusion. (itmedicalteam.pl)
  • A chest radiograph showed diffuse pulmonary infiltration and slight bilateral pleural effusion. (cdc.gov)
  • A chest x ray may show pneumomediastinum, pneumothorax, air under the diaphragm, or a pleural effusion but normal appearances do not exclude perforation and, if there is any clinical suspicion, a water soluble contrast study should be performed. (gastrotraining.com)
Mesothelioma34
20231
Exudative10
  • The goal with exudative parapneumonic effusions is to identify and intervene in the early stages, prior to the development of an empyema. (sts.org)
  • Exudative pleural effusion is a common clinical problem with various underlying causes. (jptcp.com)
  • This study aimed to assess the diagnostic utility of pleural fluid C-reactive protein (CRP) in differentiating between the etiologies of exudative pleural effusions, specifically focusing on tuberculous, malignant, and parapneumonic effusions. (jptcp.com)
  • We enrolled 60 patients with exudative pleural effusion diagnosed through clinico-radiological criteria. (jptcp.com)
  • These findings suggest that pleural fluid CRP can serve as a valuable diagnostic marker in the etiological differentiation of exudative pleural effusions, aiding clinicians in prompt and accurate decision-making for patient care. (jptcp.com)
  • 3. Radhakrishnan P, Mathanraj S. Role of pleural fluid C-reactive protein in the aetiological diagnosis of exudative pleural effusion. (jptcp.com)
  • Usefulness of pleural fluid CRP level in differential diagnosis of Exudative Pleural Effusions - A Pilot Study. (jptcp.com)
  • It has been stated that pleural fluid eosinophilia (defined as greater than 10 percent eosinophils in the pleural white cell differential count) is not helpful in the diagnosis of exudative effusions. (nih.gov)
  • Pleural fluid eosinophilia is a useful finding that can aid in the diagnosis of an exudative pleural effusion. (nih.gov)
  • Bilateral pleural effusions sometimes have different etiologies (Contarini condition)-for example, an exudative pleural effusion (empyema) in one thorax and a transudative pleural effusion (heart failure) on the other side. (manualofmedicine.com)
Sensitivity and specifi2
  • CT is the imaging modality of choice to assess pleural disease and has shown sensitivity and specificity for identifying malignancy. (medscape.com)
  • These findings on ultrasound have a sensitivity and specificity of differentiating benign from malignant effusions of 79% and 100% respectively. (hospitalprofessionalnews.ie)
Malignancy7
  • A massive effusion is often attributable to an underlying malignancy. (medscape.com)
  • 10: Does routine preparation of multiple ThinPrep ® and cell block slides improve the detection of malignancy in effusion fluid? (cytojournal.com)
  • The presence of pleural fluid eosinophilia considerably reduced the probability of malignancy or tuberculosis and increased the likelihood of an underlying benign disorder. (nih.gov)
  • Malignant pleural involvement should never be presumed and it is crucial to pathologically stage pleural effusions in the setting of malignancy. (hospitalprofessionalnews.ie)
  • Malignant involvement of the pleural space implies stage 4 malignancy thus radical treatment options such as surgery are not an option. (hospitalprofessionalnews.ie)
  • Malignancy is confirmed as the cause of an effusion when analysis of the fluid specimen shows malignant cells in either the cytology or cell block specimen. (mhmedical.com)
  • The cytologic examination of the effusion is usually required to rule out or confirm malignancy. (bvsalud.org)
Neoplasms3
  • Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
  • Gastrointestinal schwannomas are rare benign neoplasms that are distinctively unique when compared to soft-tissue and central nervous system mesenchymal neoplasms. (sages.org)
  • The outcome after surgery is excellent as these neoplasms are generally benign in nature. (sages.org)
Unilateral pleural3
Pulmonary4
  • Pleural disease occurs in the pleural space, which is the thin fluid-filled area in between the two pulmonary pleurae in the human body. (wikipedia.org)
  • [ 12 ] Rare cases of primary pulmonary or pleural DSRCT have subsequently been identified. (medscape.com)
  • Using state-of-the - art technology, the Interventional Pulmonary Program at Rhode Island Hospital offers a number of minimally invasive diagnostic and therapeutic procedures for patients with airway disorders, pleural disease and lung cancer. (lifespan.org)
  • Whether the intracardiac mass is benign or malignant, we recommend surgery due to the possibilities of systemic or pulmonary massive embolism, infection, arrhythmia and sudden death if the thrombus ruptures or the mass dislodges. (medscape.com)
Peritoneal4
  • Pleural effusion is much more common than pericardial or peritoneal effusion. (mesothelioma.net)
  • Occur in pleural, pericardial, and peritoneal spaces. (mhmedical.com)
  • The development of an effusion in the pleural, pericardial, or peritoneal space may be the initial finding in a patient with cancer, or an effusion may appear during the course of disease progression. (mhmedical.com)
  • Seventy-six cases with paraffin-embedded pleural, pericardial, and peritoneal serous effusion cell blocks including 60 malignant serous effusions (11 malignant pleural mesotheliomas and 49 metastatic carcinomas) and benign pleural effusions (14 cases with reactive mesothelial cells and 2 cases with atypical cells with uncertain significance) were selected for immunohistochemical analysis with L523S, calretinin, and CK5/6. (mesothelioma-line.com)
Empyema1
  • The conditions covered include benign and malignant pleural thickening, pleural effusions, empyema and pneumothoraces. (ox.ac.uk)
Diagnostic10
  • In the present meta-analysis, the reported studies on the diagnosis between CYFRA 21-1 and pleural effusion were assessed to summarize the diagnostic characteristics of CYFRA 21-1 in Chinese patients. (archivesofmedicalscience.com)
  • The measurement of pleural CYFRA 21-1 is likely to be a useful diagnostic tool for the confirmation of MPE. (archivesofmedicalscience.com)
  • Diagnosis of pleural effusion should lead to more diagnostic tests to find the cause. (mesothelioma.net)
  • Diagnostic value of CA 549 in pleural fluid. (nih.gov)
  • Results Mesothelin provides better diagnostic accuracy than fibulin-3 for MM whether measured in plasma or pleural effusion: area under the curve (AUC) for plasma was 0.822 (95% CI 0.76 to 0.87) compared with 0.671 (0.61 to 0.73), respectively, and for pleural fluid AUC was 0.815 (0.74 to 0.87) compared with 0.588 (0.51 to 0.67), respectively. (bmj.com)
  • Diagnostic value of procalcitonin and CRP in differentiation between some benign and malignant pleural effusions. (jptcp.com)
  • The diagnostic utility of finding eosinophils in the pleural space was assessed from its impact on prior probabilities of disease. (nih.gov)
  • Diagnostic accuracy of adenosine deaminase for pleural tuberculosis in a low prevalence setting: A machine learning approach within a 7-year prospective multi-center study. (cdc.gov)
  • Pleural fluid cytology is diagnostic in about 60% of cases. (ox.ac.uk)
  • The aim of the present study was to investigate the diagnostic efficacy of telomerase activity for discrimination of malignant and benign pleural effusions. (hacettepe.edu.tr)
Cause of pleural effusion1
Thoracic1
  • Thoracic computed tomography scans and ultrasound are helpful in distinguishing malignant from benign effusions. (ox.ac.uk)
Asbestos-related5
  • Biomarker concentrations were determined in the plasma of an additional 49 cases with benign asbestos-related disease. (bmj.com)
  • Asbestos-related pleural plaques are the most common manifestation of asbestos exposure. (msdmanuals.com)
  • The time it takes for asbestos-related pleural plaques to develop after the person is exposed to asbestos is approximately 20 to 30 years. (msdmanuals.com)
  • Often pleural plaques cause no symptoms, although because the plaques result from asbestos exposure, they increase the risk of other asbestos-related lung disease. (msdmanuals.com)
  • Asbestos-related pleural thickening is characterized by widespread, extensive thickening of the pleura. (msdmanuals.com)
Congestive heart f1
  • 8 These may be caused by bronchial obstruction from tumour or benign causes such as congestive heart failure or infection. (hospitalprofessionalnews.ie)
Cytology1
  • In cytology-negative disease, pleural biopsies are helpful. (ox.ac.uk)
Patients18
  • Laboratory evaluation of patients with a pleural effusion is directed at first determining if the effusion is an exudate or a transudate. (medscape.com)
  • Methods Fibulin-3 and soluble mesothelin were determined by ELISA in the plasma and pleural fluid of 153 patients presenting with a pleural effusion including 82 with MM, 36 with non-MM malignant effusions and 35 with benign effusions. (bmj.com)
  • MM patients with effusion fibulin-3 levels below the median survived significantly longer than those with levels above the median (14.1 vs 7.9 months, p=0.012). (bmj.com)
  • Smoking history was more prevalent among patients with malignant effusions. (jptcp.com)
  • Predictive factors, microbiology, and outcome of patients with parapneumonic effusion. (jptcp.com)
  • Patients and methods In this single-centre retrospective observational study, patient characteristics, procedural variables and outcome in patients with IPC in non-malignant pleural effusion (NMPE) were evaluated and prognostic factors for pleurodesis were identified. (bmj.com)
  • Can data on efficacy and safety of indwelling pleural catheters (IPC) in malignant pleural effusions be extrapolated on patients with non-malignant pleural effusions, where the data basis is weak? (bmj.com)
  • Pleural catheters are used to treat patients who have chronic fluid build-up in their pleural cavity, or pleural effusion. (dignityhealth.org)
  • METHODS: MRIs of 81 patients (20 bilateral), including 31 benign, 27 borderline, and 23 malignant, who had pelvic imaging between 2013-2020, were evaluated retrospectively. (bvsalud.org)
  • Patients with a score below 11.5 were classified as benign, those between 11.5-18.5 as borderline, and those over 18.5 as malignant. (bvsalud.org)
  • The size of the effusion does not reliably predict a patients symptom burden as the fluid can accumulate gradually over time allowing the patient to compensate. (hospitalprofessionalnews.ie)
  • 4 For small effusions, or patients who are liable to move post marking, intervention can be performed under real time ultrasonography. (hospitalprofessionalnews.ie)
  • Half of undiagnosed effusions in patients not known to have cancer are malignant. (mhmedical.com)
  • Patients with pleural and pericardial effusions complain of shortness of breath and orthopnea. (mhmedical.com)
  • 7. Czajka CM, DiCaprio MR. What is the proportion of patients with multiple hereditary exostoses who undergo malignant degeneration? (jms.mk)
  • Imaging plays an important role in the diagnosis and subsequent management of patients with pleural disease. (ox.ac.uk)
  • 001). CC-RT-PCR detected predominant expression of CD44v8-10 in cytologically negative samples from 11 patients who were later diagnosed with malignant disease. (elsevierpure.com)
  • Introduction: The clinical management of patients presenting with effusions requires the determination of the cause of the effusion for direction of options of management. (bvsalud.org)
Catheters2
  • Symptom palliation is the treatment goal for the majority of malignant pleural effusions and this is most commonly accomplished with chemical pleurodesis or indwelling tunneled pleural catheters. (sts.org)
  • and tunneled pleural catheters to drain fluid accumulation from around the lungs. (uclahealth.org)
Parapneumonic effusions4
  • Tuberculous effusion was the most common etiology in our study, followed by malignant and parapneumonic effusions. (jptcp.com)
  • Total leukocyte counts were higher in parapneumonic effusions. (jptcp.com)
  • Pleural fluid CRP levels were notably higher in parapneumonic effusions compared to both tuberculous and malignant effusions. (jptcp.com)
  • What are the biochemical parameters of pleural fluid that best identify parapneumonic effusions? (jptcp.com)
Volume of pleural fluid1
  • Second, the small volume of pleural fluid, which has been calculated at 0.13 mL/kg of body weight under normal circumstances, serves as a lubricant to facilitate movement of the pleural surfaces against each other in the course of respirations. (medscape.com)
Pneumothorax1
  • citation needed] Pneumothorax: a collection of air within the pleural cavity, arising either from the outside or from the lung. (wikipedia.org)
Causes of pleural1
  • The usefulness of pleural fluid presepsin, C-reactive protein, and procalcitonin in distinguishing different causes of pleural effusions. (jptcp.com)
Complications1
  • There are several disorders and complications that can occur within the pleural area, and the surrounding tissues in the lung. (wikipedia.org)
Lesions1
  • it is not easy to differentiate between benign and malignant lesions. (bvsalud.org)
Fibroma1
  • The term fibroma is inappropriate because the neoplasm exhibits defined histologic features that differ from those of fibromas and may express malignant behavior. (medscape.com)
Transudative1
Abstract2
  • Abstract: Malignant pleural effusion (MPE) is a common clinical entity affecting 40,000 people per year in the UK. (hospitalprofessionalnews.ie)
  • Hier de conclusie van deze review en daaronder een studie abstract met ranpirnasse uit 2002 met bijzonder goede resultaten op de mediane overlevingstijd. (kanker-actueel.nl)
Mesothelial2
  • however, it is not useful in differentiating atypical mesothelial cells from malignant mesothelial cells. (mesothelioma-line.com)
  • In addition, 16 cases that were originally diagnosed either as pleural effusions with reactive mesothelial cells (14) or atypical cells with uncertain significance (2) were also tested for KOC expression. (mesothelioma-line.com)
Differentiation1
  • Differentiation of malignant from benign pleural effusions based on artificial intelligence. (cdc.gov)
Bloody pleural2
  • Benign asbestos pleural effusions (BAPE) are small and bloody pleural effusions that affect one side of the lungs. (msdmanuals.com)
  • Bloody effusions are usually due to cancer, but a bloody pleural effusion can also be due to PE, trauma and, occasionally, infection. (mhmedical.com)
Pleura3
  • Analysis of the pleural fluid and histopathology of the pleura revealed lung adenocarcinoma. (itmedicalteam.pl)
  • Neoplasia poco frecuente, generalmente benigna, derivada de los fibroblastos mesenquimatosos localizados en la zona submesotelial de la PLEURA. (bvsalud.org)
  • A rare neoplasm, usually benign, derived from mesenchymal fibroblasts located in the submesothelial lining of the PLEURA. (bvsalud.org)
Pleurodesis2
Pericardial effusion2
  • Transthoracic echocardiogram showed a large pericardial effusion with diastolic collapse of the right ventricle and a hypotransparent mass (4×1.6?cm) attached to the visceral pericardium in the right apex (video 1). (lamblawoffice.com)
  • The differential diagnosis of a malignant pleural or pericardial effusion includes nonmalignant processes, such as infection, PE, heart failure, and trauma. (mhmedical.com)
Findings2
  • The most common findings on physical examination (79%) are signs of pleural effusion (eg, dullness to percussion, decreased breath sounds). (medscape.com)
  • This review will focus on the main nonmalignant and malignant respiratory outcomes associated with exposure to Libby vermiculite, with emphasis on recent findings. (cdc.gov)
Large pleural1
Occur5
  • Pleural thickening can occur as a result of any inflammation occurring in the lungs. (cancer.org)
  • A strong exposure-response relationship exists for many malignant and nonmalignant outcomes and the most common outcome, pleural plaques, may occur at low lifetime cumulative exposures. (cdc.gov)
  • These effusions generally occur within 10 years of exposure to asbestos. (msdmanuals.com)
  • Chylous pleural or ascitic fluid is generally associated with obstruction of lymphatic drainage as might occur in lymphoma. (mhmedical.com)
  • Clinical behavior is typically benign, although rare local recurrences occur. (cap.org)
Cavity1
Carcinomas1
  • Immunohistochemical studies showed that positive staining for KOC of variable degrees of intensity was observed in 47 of 60 cases in malignant serous effusions including 10 of 11 mesotheliomas and 36 of 49 metastatic carcinomas. (mesothelioma-line.com)
Interstitial1
  • [ 12 , 13 ] In addition, the risk of developing pleural or interstitial abnormalities was more than triple in the ANA-positive individuals than it was in persons who were ANA negative. (medscape.com)
Etiology3
  • The study participants were categorized into groups based on the etiology of their effusions as malignant, parapneumonic and tubercular effusions. (jptcp.com)
  • Co-morbid conditions like hypertension and diabetes did not correlate significantly with effusion etiology. (jptcp.com)
  • Thoracentesis is usually performed to evaluate pleural effusions of unknown etiology. (manualofmedicine.com)
Conclusions2
  • Conclusions: CC-RT-PCR analysis of CD44v8-10 expression could be an important adjunct to cytologic examination in cancer diagnosis, especially in detecting exfoliated cancer cells in pleural effusions and urine. (elsevierpure.com)
  • Conclusions: Malignant effusions constituted 17 percent of all the effusions examined. (bvsalud.org)
Lung and pleural1
  • Overlapping lung and pleural involvement in individual cases has given rise to the more inclusive term "pleuropulmonary" synovial sarcoma. (medscape.com)
Clinical2
  • After the initial stabilization of the patient, clinical suspicion for pleural effusion should be confirmed with appropriate radiographic evaluation. (medscape.com)
  • The clinical presentation varies depending on the underlying cause of the effusion and how rapidly the pleural fluid accumulated. (manualofmedicine.com)
Synovial sarcoma1
  • Synovial sarcoma is a malignant soft-tissue neoplasm that most commonly affects the extremities near to, but not in continuity with, large joints. (medscape.com)
Buildup of fluid1