• 3 Diagnosis often is obvious from the usual clinical presentation (cough, dyspnea) and radiologic findings (hilar lymphadenopathy), but biopsy of cutaneous lesions may provide confirmatory information in unclear cases. (aafp.org)
  • The lesion is characterized by a proliferation of both melanocytes and keratinocytes that results in pigmented macular or plaquelike lesions (see image below). (medscape.com)
  • [ 1 ] Bloch described several skin lesions, which he originally called benign nonovoid melanoepithelioma of the skin. (medscape.com)
  • Although cutaneous lesions of melanoacanthoma were reported as early as 1927, Tomich et al at the American Academy of Oral Pathology first reported oral mucosal lesions in 1978. (medscape.com)
  • The cutaneous variant is more common, but it is still relatively rare among skin lesions. (medscape.com)
  • A retrospective study of 643 cutaneous horns examined in our department between 1970 and 1989 revealed that 38.9% were derived from malignant or premalignant epidermal lesions, and 61.1% from benign lesions. (forestbpms.co)
  • H&E staining of cutaneous lesions may show necrotizing granuloma formation and neutrophilic infiltrate. (amboss.com)
  • The presence of single or multiple raised cutaneous lesions characterize this self-healing disorder. (biomedcentral.com)
  • Skin lesions found in TSC include ash leaf spots, Shagreen patches, and adenoma sebaceum (multiple smooth papules that are benign angiofibromas). (uspharmacist.com)
  • Cobb syndrome is a rare, non-inherited disorder characterized by visible skin lesions with underlying spinal angiomas or arteriovenous malformations (AVM). (nicklauschildrens.org)
  • We isolated and characterized cell cultures from eutopic endometrium and endometriotic lesions of women with malformations of the internal reproductive organs. (endometriosi.it)
  • It is characterized by the onset of vascular reddish macules and papules during childhood, lesions are usually monolateral with a linear serpiginous pattern. (biomedcentral.com)
  • In contrast, cutaneous lesions are linked directly to fair-skinned and blue-eyed persons with a history of blistering sunburns, and the incidence has increased dramatically (approximately 4-6% per year) over the same period. (medscape.com)
  • Prognosis regarding the clinical behavior of the mucosal lesions has been extrapolated from knowledge of the cutaneous lesions. (medscape.com)
  • The diagnosis is difficult because of the slow course of the lesions, which present initially as apparently benign atrophic morphoeaor keloid -like plaques. (lookfordiagnosis.com)
  • Oral pigmented lesions result from cellular hyperplasia that can range from benign nevi to fatal oral melanoma . (medscape.com)
  • The result of the infection is usually a benign, mild skin disease characterized by lesions (growths) that may appear anywhere on the body. (shadowebike.com)
  • While the skin tumors associated with CYLD cutaneous syndrome are typically benign, occasionally they may become cancerous (malignant). (medlineplus.gov)
  • TdT may assist dermatopathologists in discriminating malignant infiltrates of T-ALL from other conditions. (karger.com)
  • Lymphocytic infiltrates in the skin, both malignant and benign, can have overlapping clinical and histological features, presenting a diagnostic challenge. (karger.com)
  • Moreover, a lesion's benign or malignant nature is not obvious in all cases. (forestbpms.co)
  • Cutaneous horn (cornu cutaneum) is the clinical description of a hyperproliferation of compact keratin in response to a wide array of underlying benign and malignant pathologic changes. (forestbpms.co)
  • Tumors may be benign or malignant (cancerous). (merckvetmanual.com)
  • Aouidad et al reported the case of a 51-year-old woman presenting with orbital "pseudotumors" (I do not understand why these are not just "tumors" - large swellings of any cause that may be benign or malignant) that histologically demonstrated eosinophilic angiocentric sclerosis related to IgG4. (aad.org)
  • Despite being initially considered a benign disease, it is widely thought nowadays that endometriosis and especially ovarian endometriomas are neoplastic conditions with the potential to become malignant. (endometriosi.it)
  • Patients with oral malignant melanoma often recall having an existing oral pigmentation months to years before diagnosis, and the condition may even have elicited prior comment from examining physicians and dentists (or healthcare providers, when considering the auxiliaries). (medscape.com)
  • Skin nonmelanocytic tumor - Atypical fibroxanthoma (AFX), Rare, low grade, malignant cutaneous tumor of uncertain differentiation, first described in the 1960s by EB Helwig Atypical fibroxanthoma (AFX) is a dermal spindle-cell tumour that typically occurs on the head and neck of sun damaged older people. (netlify.app)
  • subtypes of cutaneous T-cell lymphoma, SS is a malignant neoplasm originating the most common of which are mycosis from T lymphocytes, which involves the fungoides and Sézary syndrome (SS). (bvsalud.org)
  • Pancreatic endocrine tumor, also known as pancreatic neuroendocrine tumor (PNET), describes a group of endocrine tumors originating in the pancreas that are usually indolent and benign, but may have the potential to be malignant. (findzebra.com)
  • A group of disorders having a benign course but exhibiting clinical and histological features suggestive of malignant lymphoma. (lookformedical.com)
  • Pseudolymphoma is characterized by a benign infiltration of lymphoid cells or histiocytes which microscopically resembles a malignant lymphoma. (lookformedical.com)
  • Dermatosis papulosa nigra is characterized by multiple, firm, smooth, dark brown to black, flattened papules that measure 1-5 mm in diameter. (medscape.com)
  • Reactive angioendotheliomatosis (RAE) is a rare benign cutaneous vascular proliferation characterized by intravascular hyperplasia of endothelial cells and tuft-like proliferation of vessels. (thedoctorsdoctor.com)
  • Cutaneous biopsy revealed RAE characterized by the proliferation of epithelioid and spindle-shaped cells in superficial and middermis lining vascular channels, arranged in clusters, and sometimes displaying an intravascular growth pattern. (thedoctorsdoctor.com)
  • Histopathologically, it is characterized by a proliferation of endothelial cells within vascular lumina resulting in the obliteration of the involved vessels. (thedoctorsdoctor.com)
  • It consists of violaceous and purpuric plaques histopathologically characterized by diffuse proliferation of endothelial cells interstitially arranged between collagen bundles of the reticular dermis. (thedoctorsdoctor.com)
  • Bone dysplasia is described as a benign disorder of bone development, characterized by the replacement of normal bone by an excessive proliferation of fibrous connective tissue. (bvsalud.org)
  • TSC is characterized by autosomal-dominant mutations in the TSC1 or TSC2 genes (encoding for the protein Hamartin on chromosome 9q34 and Tuberin on chromosome 16q13 respectively) leading to overactivation of the mTOR (mechanistic target of rapamycin) pathway with increased cell proliferation and a range of other consequences. (uspharmacist.com)
  • Benign proliferation of the ENDOMETRIUM in the UTERUS. (lookformedical.com)
  • More than one type of skin tumor often develops, including benign growths called cylindromas, spiradenomas, and trichoepitheliomas. (medlineplus.gov)
  • Spiradenomas are related to cylindromas and it is common to find features of both of these benign growths in a single tumor. (medlineplus.gov)
  • Immunostaining for terminal deoxynucleotidyl transferase (TdT) was positive in tumor cells, supporting the diagnosis of cutaneous involvement by T-ALL. (karger.com)
  • In most cases, cutaneous horns are a form of a skin tumor. (forestbpms.co)
  • Distinguishing a benign tumor from a cancerous tumor requires specialized knowledge and laboratory equipment. (merckvetmanual.com)
  • Treatment for a particular tumor depends largely on the type of tumor, its location and size, and the overall physical condition of the dog. (merckvetmanual.com)
  • A glomus tumor or glomangioma is a rare, benign growth of blood vessels which can develop in both adults and children. (nicklauschildrens.org)
  • AFX usually has a benign clinical course and complete tumor resection is generally curative. (netlify.app)
  • Reactive angioendotheliomatosis (RAE) is a benign cutaneous vascular disorder characterized by a distinct histologic and clinical appearance. (thedoctorsdoctor.com)
  • This article reviews the most common cutaneous T-cell lymphomas: mycosis fungoides (both classic and variant forms) as well as its leukemic counterpart Sézary syndrome, CD30+ T-cell lymphoproliferative disorders including the ever-expanding group of lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma, and primary cutaneous CD4+ small/medium lymphoproliferative disorder. (bvsalud.org)
  • Juvenile xanthogranuloma is a benign and self-healing disorder which is characterized by the presence of single or multiple raised cutaneous nodules, yellow-brown to reddish in color and usually measuring from a few millimeters to a few centimeters in diameter. (biomedcentral.com)
  • Jessner lymphocytic infiltration of the skin is an uncommon skin disorder characterized by benign accumulations of lymphocytes by a "coat-sleeve"-like perivascular infiltration in the skin [1]. (who.int)
  • Vitiligo is an acquired pigmentary disorder of the skin that is caused by unknown factors and is characterized by white and depigmented patches that enlarge and become more numerous with time. (e-ijd.org)
  • Cutis marmorata telangiectatica congenita (CMTC) is an uncommonly reported, sporadic, congenital cutaneous disorder. (nicklauschildrens.org)
  • Maffucci syndrome is a rare genetic disorder of unknown cause characterized by benign enlargements of cartilage, bone deformities, and dark, irregularly shaped hemangiomas. (nicklauschildrens.org)
  • Generalized pustular psoriasis (GPP) is a rare, chronic, and severe inflammatory skin disorder characterized by sudden eruption of sterile pustules, often accompanied by systemic inflammation. (springer.com)
  • Cutaneous vasculitis (CV), a condition characterized by palpable purpura and nonspecific histopathologic findings, presents a diagnostic and therapeutic challenge because it may be a primary disorder or it may be a cutaneous manifestation of another entity, such as systemic necrotizing vasculitis, connective tissue disease, systemic bacterial infection, or malignancy. (qxmd.com)
  • Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by intestinal hamartomatous polyps in association with mucocutaneous melanocytic macules. (medscape.com)
  • 41] This disorder also referred to as marginal papular keratoderma is characterized by skin colored papules around 2-4 mm occurring circumferentially over the hands, feet, and digits. (shadowebike.com)
  • This article reviews selected pulmonary diseases with distinctive cutaneous findings. (medscape.com)
  • Neurocutaneous syndromes are characterized by distinctive cutaneous stigmata and neurologic symptomology. (uspharmacist.com)
  • The prognosis for patients with dermatosis papulosa nigra is excellent since it is not a premalignant condition nor is it associated with any underlying systemic disease. (medscape.com)
  • Reactive angioendotheliomatosis is a rare benign process that has been mainly described in patients with systemic infections, such as subacute bacterial endocarditis or tuberculosis, and in association with intravascular deposition of cryoproteins. (thedoctorsdoctor.com)
  • Variously described as a vasculopathy, endovasculitis, or occlusive arteriopathy, this condition occurs in a benign cutaneous form and a lethal multiorgan systemic variant. (bvsalud.org)
  • In 1969, Rosai and Dorfman first described a newly recognised benign systemic histioproliferative disease characterised clinically by bilateral striking cervical lymphadenopathy, fever, leukocytosis, and. (annals.edu.sg)
  • Examples of autoimmune conditions include the following: Rheumatoid arthritis (RA) Type 1 diabetes Crohn's Disease Hashimoto's thyroiditis Neurological diseases Multiple Sclerosis (MS) Glomerulanephritis Pernicious Anaemia Goodpasture's syndrome Scleroderma Raynaud's Phenomenon Lupus (e.g., systemic lupus erythematosus [SLE]) Inflammatory bowel disease (IBD). (ecopolitan.com)
  • The association of the limited cutaneous form of systemic scleroderma (lcSSc) and PBC is known as Reynolds syndrome. (journalmc.org)
  • Systemic sclerosis (SSc) is a connective tissue disease characterized by inflammatory, fibrotic and degenerative changes. (journalmc.org)
  • The association between PBC and other autoimmune conditions, such as Sjögren's syndrome, rheumatoid arthritis, Hashimoto's thyroiditis or systemic sclerosis occurs in 84% of cases [ 1 , 2 , 6 - 10 ]. (journalmc.org)
  • We report a 63-year-old Caucasian male who developed multiple cutaneous eruptive keratoacanthomas after starting sorafenib 400 mg twice daily. (biomedcentral.com)
  • A 63-year-old Caucasian male with known hepatocellular carcinoma presented with multiple cutaneous eruptive keratoacanthomas approximately three and half months after starting sorafenib 400 mg twice daily. (biomedcentral.com)
  • Granuloma faciale (GF) is an uncommon benign chronic skin disease of unknown origin characterized by single or multiple cutaneous nodules, usually occurring over the face. (medscape.com)
  • Infantile hemangiomas are benign tumors characterized by an overgrowth of blood vessels. (pharmacytimes.com)
  • Combined hamartomas of the retina and RPE are rare intraocular tumors characterized by the malformation of the neurosensory retina, RPE and adjacent vitreous. (reviewofoptometry.com)
  • Combined hamartomas of the retina and retinal pigment epithelium (CHRRPE) are rare, congenital, intraocular tumors characterized by the malformation of the neurosensory retina, RPE and adjacent vitreous with disorganized glial, vascular and melanocytic tissue. (reviewofoptometry.com)
  • There are several variants of cutaneous melanocytic tumors, characterized by differing clinical and pathologic features. (atlasgeneticsoncology.org)
  • Conditions such as melanotic macules , nevi, smoker's melanosis , amalgam and graphite tattoos, racial pigmentation , and vascular blood-related pigments occur with some frequency. (medscape.com)
  • Pigmented macules on the cutaneous surfaces covering the extremities and face are less frequently observed. (medscape.com)
  • A 30-year-old man presented with asymptomatic erythematous nodules and plaques on the face where he had suffered cutaneous leishmaniasis (CL) 5 years before, which had improved leaving an atrophic scar ( Figure 1A ). (who.int)
  • Solitary or multiple benign cutaneous nodules comprised of immature and mature vascular structures intermingled with endothelial cells and a varied infiltrate of eosinophils, histiocytes, lymphocytes, and mast cells. (lookformedical.com)
  • While some studies report approximately fewer than 100 reported cases, it would be legitimate to point out that the low case published reports may be attributed to the benign nature of lesion appearance, rate and timing of manifestations, and potential differential diagnosis of amalgam tattoo, for example, which though common, are not routinely reported nor typically addressed with treatment owing to the location of the lesion and treatment options. (medscape.com)
  • A competent clinician must understand the pathophysiologies of GU tract pathologies to understand their manifestations on clinical examinations and also grasp the need to screen for particular conditions throughout a patient's lifetime. (lecturio.com)
  • diagnosis at a glance may be possible because of the perioral cutaneous manifestations. (lookfordiagnosis.com)
  • Dermatomyositis is an idiopathic inflammatory myopathy with several characteristic cutaneous manifestations. (shadowebike.com)
  • OBJECTIVES: This study assessed the incidence of DUSP22 rearrangement and its clinical and immunohistochemical implications in primary cutaneous anaplastic large-cell lymphoma (pcALCL), lymphomatoid papulosis (LyP) and CD30+ mycosis fungoides with large-cell transformation (MF-LCT), focusing especially on the association with the prognosis and LEF1 expression pattern. (bvsalud.org)
  • There was no sign of dermal oedema seen in polymorphous light eruption and no germinal follicle formation as would be observed in lymphocytoma cutis or cutaneous follicular centre cell lymphoma. (who.int)
  • Cutaneous T-cell lymphoma is a general term from mycosis fungoides or occur spontane- to identify non-Hodgkin's T-cell lymphomas ously, although some authors now consider that primarily affect the skin. (bvsalud.org)
  • 2 , 3 Additional clinical features that help distinguish this diagnosis are perilesional cutaneous anesthesia and exposure to an endemic area (especially Brazil, India, southern Africa, Myanmar, and Nepal). (aafp.org)
  • Every histopathological report with cutaneous horn diagnosis was reviewed, the variables age, gender, location of lesion, size, evolution and cutaneous horns base pathologies were reviewed. (forestbpms.co)
  • The patient had a known history of actinic keratosis and cutaneous squamous cell carcinomas (first diagnosed more than 4 years before starting sorafenib) and had two well-differentiated squamous cell carcinomas completely excised on his right cheek about 2 months before the diagnosis of hepatocellular carcinoma (HCC). (biomedcentral.com)
  • The recognition and correct interpretation of cutaneous signs of diseases that primarily affect the bronchopulmonary system may aid the clinician in diagnosis and assessment of prognosis. (medscape.com)
  • Lack of standardized criteria in the international guidelines and the heterogeneity of cutaneous and extracutaneous symptoms make the diagnosis of GPP difficult. (springer.com)
  • Clinical criteria for description and diagnosis of pustular conditions, including GPP, are variable and there is no specific agreement on commonly sustained concepts. (springer.com)
  • These lymphomas exhibit variable prognosis, and therefore it is important to correctly classify atypical cutaneous T-cell infiltrates for appropriate patient treatment and prognosis. (bvsalud.org)
  • We report here on a case of Jessner lymphocytic infiltration associated with an atrophic scar due to cutaneous leishmaniasis from 5 years before. (who.int)
  • The condition, now known as Jessner lymphocytic infiltration of the skin, is poorly understood and indeed the very existence of such a condition has been questioned. (who.int)
  • There are no other reports of Jessner lymphocytic infiltration following CL and this is the first time that this condition was reported as presenting on the scar of parasitic diseases from CL. (who.int)
  • Severe long-standing clubbing is characterized by interstitial edema and infiltration by plasma cells and lymphocytes. (medscape.com)
  • Cutaneous T-cell lymphomas are an heterogeneous group of uncommon lymphoid neoplasms that are challenging to diagnose and require close collaboration between dermatologists, pathologists and hematologists/oncologists. (bvsalud.org)
  • 6] Case reports have described AN associated with hematologic malignancies, including acute myeloid leukemia, and even benign gastrointestinal neoplasms. (medscape.com)
  • others apply also to benign neoplasms. (netlify.app)
  • Clinicians must visually inspect the oral cavity, obtain good clinical histories, and be willing to perform a biopsy on any pigmented condition that is not readily explainable or diagnosed. (medscape.com)
  • According to the American Academy of Ophthalmology , xanthelasma is a skin condition characterized by yellow or orange growths on or near the eyelids, which can be raised or flat. (firstforwomen.com)
  • Mastocytosis , melanocytosis , cutaneous lymphosarcoma , and vascular hamartomas are found in calves. (msdvetmanual.com)
  • Solitary or multiple benign hepatic vascular tumors, usually occurring in women of 20-50 years of age. (lookformedical.com)
  • 2 The condition usually begins with an asymptomatic, flesh-colored papule that undergoes central involution and slowly develops into a ring-shaped lesion. (aafp.org)
  • A cutaneous horn is a type of lesion or growth that appears on the skin. (forestbpms.co)
  • A cutaneous horn, also known as cornu cutaneum, refers to a specific appearance of a skin lesion in which a cone-shaped protuberance arises on the skin caused by overgrowth of the most superficial layer of skin (epidermis). (forestbpms.co)
  • atypical squamous cells cannot exclude high grade squamous intraepithelial lesion Fibroxanthoma (M8830/0) - see also Neoplasm, connective tissue, benign. (netlify.app)
  • CYLD cutaneous syndrome is a genetic condition characterized by the growth of multiple noncancerous (benign) skin tumors. (medlineplus.gov)
  • People with CYLD cutaneous syndrome typically begin developing tumors in late childhood or in their teens. (medlineplus.gov)
  • For reasons that are unclear, females with CYLD cutaneous syndrome tend to develop more tumors than males with this condition. (medlineplus.gov)
  • The tumors in CYLD cutaneous syndrome can be disfiguring and may contribute to depression or other psychological problems. (medlineplus.gov)
  • CYLD cutaneous syndrome includes the conditions previously called Brooke-Spiegler syndrome, multiple familial trichoepithelioma, and familial cylindromatosis. (medlineplus.gov)
  • The prevalence of CYLD cutaneous syndrome is unknown, but the condition is estimated to affect more than 1 in 100,000 individuals. (medlineplus.gov)
  • CYLD cutaneous syndrome is caused by mutations in the CYLD gene . (medlineplus.gov)
  • People with CYLD cutaneous syndrome are born with a mutation in one of the two copies of the CYLD gene in each cell. (medlineplus.gov)
  • In people with CYLD cutaneous syndrome, a second CYLD gene mutation typically occurs in multiple cells over an affected person's lifetime. (medlineplus.gov)
  • Cases of other less common etiologies: pulmonary amoebiasis, antiphospholipid syndrome, chronic lymphocytic leukemia, thoracic actinomycosis, invasive epidermoid carcinoma, cutaneous polyarteritis, and merkel cell carcinoma [4-10] have also been reported. (escholarship.org)
  • In the outpatient setting, recognizing the early cutaneous presentation of superior vena cava syndrome requires a high index of suspicion. (escholarship.org)
  • Cutaneous and endocrine changes may be associated with polyostotic dysplasia, characterizing the McCune-Albright syndrome. (bvsalud.org)
  • This syndrome is a cutaneous marker for renal cystadenocarcinoma and uterine leiomyoma. (msdvetmanual.com)
  • Cutaneous toxicities of sorafenib are common, including cutaneous eruptions (such as truncal erythema and seborrheic-dermatitis-like changes) and hand-foot syndrome. (biomedcentral.com)
  • A syndrome due to myocardial oxygen deficit, characterized by prolonged substernal, thoracic pain which is precipitated chiefly by emotion, exercise, or the ingestion of a heavy meal. (ecopolitan.com)
  • Bannayan-Riley-Ruvalcaba syndrome (BRRS) is a rare condition with hamartomatous polyps of the small and large intestines. (nicklauschildrens.org)
  • Gorham syndrome is a rare condition involving gradual bone loss that can affect one or more bones. (nicklauschildrens.org)
  • AIDS-like syndrome: AIDS-like disease (illness) (syndrome) ARC AIDS-related complex Pre-AIDS AIDS-related conditions Prodromal-AIDS 3. (cdc.gov)
  • The disease mimics many other dermatoses and can be confused with conditions, such as sarcoidosis, discoid lupus erythematosus, mycosis fungoides, and fixed drug eruption. (medscape.com)
  • Cutaneous larvae migrans is characterized by a thin, erythematous, serpiginous papular eruption caused by hookworm larvae traveling through the skin. (aafp.org)
  • An early and prominent symptom of this condition is a constellation of superficial, dilated, vertically oriented and tortuous cutaneous venules or veins above the ribcage margins, often presenting as a blanchable violaceous eruption. (escholarship.org)
  • Spitz tumors include a group of cutaneous melanocytic tumors that share certain histologic features. (atlasgeneticsoncology.org)
  • His past medical history revealed only benign prostatic hyperplasia and arterial hypertension. (journalmc.org)
  • Most of these conditions are uncommon to rare. (msdvetmanual.com)
  • Cutaneous polyarteritis nodosa (CPN) is an uncommon form of vasculitis of the small-and medium-sized arteries in the reticular dermis and subcutaneous tissue. (annals.edu.sg)
  • Jessner and Kanof first described as an uncommon skin condition in 1953 [4]. (who.int)
  • Oral melanomas are uncommon (1.2 cases per 10 million population per year in the United States), and, similar to their cutaneous counterparts, they are thought to arise primarily from melanocytes in the basal layer of the squamous mucosa. (medscape.com)
  • It is characterized by annular, flesh-colored or slightly erythematous plaques and papules that are generally asymptomatic. (aafp.org)
  • One or more 5-10 mm large, erythematous , nontender cutaneous papules or vesicles develop approx. (amboss.com)
  • It is characterized by a narrowing and occlusion of the lumen of small to medium-sized blood vessels, leading to ischemia and infarction in the involved organ systems. (bvsalud.org)
  • Facial angiofibromas (benign tumors made up of blood vessels and fibrous tissues) are found in 75% of patients with TSC and are characterized by reddish spots or bumps on the face in a butterfly distribution. (uspharmacist.com)
  • In cats, familial benign mastocytosis is described in young Siamese cats. (msdvetmanual.com)
  • Botulinum toxin has also been used experimentally in the treatment of many other dermatological conditions with positive results, including persistent facial flushing, gustatory sweating, anal fissures, familial benign pemphigus, dyshidrotic eczema, and surgical wound closures. (jcadonline.com)
  • Granuloma annulare is a benign, self-limited cutaneous condition. (aafp.org)
  • Pathological Considerations Also called Little's Disease or Congenital Spastic Paralysis, this condition is usually the result of developmental defects in the brain or central nervous system or from trauma at birth. (ecopolitan.com)
  • Central cyanosis is often a manifestation of congenital heart disease characterized by right-to-left pulmonary shunts. (medscape.com)
  • This is a rare congenital medical condition of abnormal blood and lymph vessel formation, cutaneous capillary malformation, and skeletal or soft tissue hypertrophy. (nicklauschildrens.org)
  • They can skin and can extend to the bone marrow, simulate benign skin disorders, making them blood lymphocytes, lymph nodes, and a diagnostic challenge for dermatologists1,2. (bvsalud.org)
  • We report two patients with reactive cutaneous angioendotheliomatosis appearing distally to arteriovenous fistulas used for hemodialysis because of chronic renal failure. (thedoctorsdoctor.com)
  • Endometriosis is a chronic inflammatory disease characterized by the elevation of proinflammatory cytokines, such as IL-6, in the peritoneal fluid. (endometriosi.it)
  • Primary biliary cirrhosis (PBC) is a chronic liver condition characterized by bile duct destruction, probably caused by a yet unknown immunological mechanism. (journalmc.org)
  • The CDC Surveillance Coordination Group has established a steering committee that is charged with the development of a broad range of case definitions for noninfectious conditions (e.g., environmental or occupational conditions, chronic diseases, adverse reproductive health events, and injuries). (cdc.gov)
  • The ICD-10-CM code D48.5 might also be used to specify conditions or terms atypical fibrous histiocytoma of soft tissue , atypical fibroxanthoma of skin, etc. (netlify.app)
  • Atypical fibroxanthoma (AFX) is a cutaneous neoplasm of mesenchymal origin. (netlify.app)
  • this finding, however, is not pathognomonic, as such cells may be seen in other inflammatory conditions. (aad.org)
  • The first patient showed intravascular reactive angioendotheliomatosis, while the second one had purpuric plaques that were characterized histopathologically by diffuse dermal angioendotheliomatosis. (thedoctorsdoctor.com)
  • On exam he displayed prominent non-pitting infraorbital edema (Figure 1), as well as jagged, blanching, violaceous plaques on the upper chest and abdomen (Figure 2), which were interpreted as dilated cutaneous vessels. (escholarship.org)
  • It is thought to be hereditary and is characterized by symmetric, firm plaques on the trunk that consist of thick bundles of collagen replacing the normal dermis and panniculus. (msdvetmanual.com)
  • Eyelid xanthelasma is the most common form of cutaneous xanthoma, characterized by yellowish patches on the eyelid's skin. (rbcp.org.br)
  • This pathological condition has subsequently been reported under various names such as nevoxanthoendothelioma, juvenile xanthoma or xanthoma tuberosum [ 2 ]. (biomedcentral.com)
  • Dermatosis papulosa nigra (DPN) is a benign cutaneous condition common among Black people. (medscape.com)
  • We offer diagnostic and treatment options for common and complex medical conditions. (massgeneral.org)
  • Oral pigmentation is a relatively common condition that may involve any portion of the oral cavity. (medscape.com)
  • Treatment of inverse psoriasis can be difficult and requires a different approach to the more common cutaneous forms of the disease due to the sensitivity of skin in the susceptible areas. (jcadonline.com)
  • Ameloblastoma is a benign epithelial odontogenic neoplasm which is common amongst the Yoruba ethinc group. (bvsalud.org)
  • From the abstract: 'We identified 40 germline genetic observations that led directly to new targets and subsequently to novel approved therapies for 36 rare and 4 common conditions. (cdc.gov)
  • The therapies approved for common conditions are all inhibitors designed to pharmacologically mimic the natural, disease-protective effects of rare loss-of-function variants. (cdc.gov)
  • N eurocutaneous disorders are a heterogeneous group of genetic disorders characterized by abnormalities of the cutaneous and nervous systems. (uspharmacist.com)
  • TSC is a multisystemic neurocutaneous genetic condition characterized by hamartomas that affect multiple organs, including the skin, central nervous system, heart, lungs, and kidney. (uspharmacist.com)
  • In recent years, notable progress has been made in genetic testing and imaging techniques, enhancing our ability to diagnose these conditions. (e-acfs.org)
  • Oral melanoacanthoma is regarded by many as a reactive condition unrelated to cutaneous melanoacanthoma, but the histologic features are similar. (medscape.com)
  • The mucosal variants of melanoacanthoma have histologic appearances similar to those of cutaneous melanoacanthoma. (medscape.com)
  • Cutaneous pigmentation is determined by the amounts of eumelanin and pheomelanin synthesized by the epidermal melanocytes and interference of melanocortin-1 receptor (MC1R), a G-protein coupled receptor, its normal agonist, alpha-melanocyte stimulating hormone (α-MSH), and key enzymes, such as tyrosinase, to protect against sun-induced DNA damage. (e-ijd.org)
  • Cutaneous melanoacanthoma and mucosal melanoacanthoma differ in terms of patient age, patient race, and site. (medscape.com)
  • In contrast to cutaneous melanomas, which are etiologically linked to sun exposure, risk factors for mucosal melanomas are unknown. (medscape.com)
  • AFX was first reported by Helwig in the early 1960s and is characterized as a neoplasm of low-grade malignancy of fibroblastic origin. (netlify.app)
  • Fibroxanthoma - see also Neoplasm, connective tissue, benign. (netlify.app)
  • A hemangiopericytoma is a very rare soft tissue mass due to overgrowth of capillaries that is almost always benign. (nicklauschildrens.org)
  • Differentiation of GPP from other similar conditions/diseases is important and requires careful assessments. (springer.com)
  • In this course, the student will be introduced to the pathophysiologies of conditions that affect the female and male GU tracts, STDs, diseases of the ovaries and testicles, and hormone-related ailments. (lecturio.com)
  • This report supersedes the 1990 report, which included infectious diseases and one noninfectious condition (i.e., spinal cord injury). (cdc.gov)
  • Melanoacanthoma is a rare condition of oral mucosa that has been reported only in the last century. (medscape.com)
  • The condition usually occurs in children and young adults and has familial predilection, lasting for several months, sometimes years, before running its course. (lookformedical.com)
  • A wide range of cutaneous signs may be related to internal malignancy. (medscape.com)
  • It may be classified as diffuse cutaneous SSc or limited cutaneous SSc (lcSSc) on the basis of the extent and distribution of skin involvement. (journalmc.org)
  • I thought nothing of it until recently, when I happened upon an article about xanthelasma, a skin condition that may indicate high cholesterol and heart disease. (firstforwomen.com)
  • Research from the Journal of Cutaneous and Aesthetic Surgery notes that about half of the people who have xanthelasma have hyperlipidemia. (firstforwomen.com)
  • Physical examination showed mild skin thickening of forearms and moderate skin thickening of hands (according to modified Rodnan skin score), sclerodactyly, cutaneous calcifications in the forearms, pitting digital ulcers in the 2nd and 3rd fingers of the right hand and facial telangiectasias. (journalmc.org)