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  • thickness
  • Another question of interest is the effective dosing of biocide, i.e., exploring dosing strategies that could minimize the number of living cells or biofilm thickness. (osu.edu)
  • Third, the hydrodynamic environment can affect biofilm density and thickness ( 2 , 18 , 25 ), which in turn can affect signal gradients. (asm.org)
  • biological
  • Several physical, biological, and chemical factors have the potential to influence QS in biofilm systems ( 12 ). (asm.org)
  • We especially encourage the submission of work applying physical, analytical, and modeling methods to generate insights into the interactions that shape biofilms and determine their function and biological outcomes. (frontiersin.org)
  • simulate
  • Computational modeling is the use of computers to simulate and study the behavior of complex systems using mathematics, physics and computer science. (nih.gov)
  • depends
  • Net demineralization or net remineralization is determined by the local tooth surface environment and depends on biofilm behavior, pH, and the concentrations of bioavailable calcium and phosphate. (dentalproductshopper.com)
  • The functioning of the biofilm depends on many parameters including electrode potential, surface properties and charge transfer approach. (caltech.edu)
  • detachment
  • In this talk a biofilm model with growth and detachment is discussed, hence, making the model interesting in applications. (osu.edu)
  • stability
  • The aim of de novo protein design is to find the amino acid sequences that will fold into a desired 3-dimensional structure with improvements in specific properties, such as binding affinity, agonist or antagonist behavior, or stability, relative to the native sequence. (jove.com)
  • concentrations
  • demonstrated that biofilms present on rocks submerged in flowing aquatic systems produce measurable amounts of AHLs ( 14 ), supporting the idea that physiologically relevant concentrations of signal might be present in some environmental biofilm systems. (asm.org)
  • structures
  • In practice, the student should observe adhesion of cells to the inside of the glass wall, the growth of complex biofilm structures, the sloughing of biofilm masses and re-growth of biofilm in these denuded areas. (montana.edu)
  • communities
  • This paper describes the utility of CMEIAS (Center for Microbial Ecology Image Analysis System) computer-assisted microscopy to extract data from accurately segmented images that provide 63 different insights into the ecophysiology of microbial populations and communities within biofilms and other habitats. (mdpi.com)
  • One potential answer is in surface-associated communities called biofilms. (asm.org)
  • stages
  • The degree of pathogenicity is affected by the variety of "stages" of a biofilm when interacting with the host. (ndnr.com)
  • Consistent with convention, I will use the term "Phase-1" biofilms for those in earlier stages of development that are less significantly pathogenic (at times even considered normal), and I will use the term "Phase-2" biofilms for those that are in later and more complex stages of development and which are universally pathogenic and impediments to cure. (ndnr.com)
  • Observation over time will permit the student to follow the various stages in biofilm development. (montana.edu)
  • increases
  • Transport studies suggest that, for both types of nanoparticles tested, the particle attachment efficiency to the collector surface generally increases (up to 6 fold in NaCl and 26 fold in CaCl 2 ) in the presence of biofilm. (rsc.org)
  • model
  • We prove the existence and uniqueness of bounded non-negative solutions of this system and study the behavior of the model in numerical simulations, where we focus on hollowing effects in established biofilms. (aimsciences.org)
  • University of Notre Dame applied mathematician Mark Alber and environmental biotechnologist Robert Nerenberg have developed a new computational model that effectively simulates the mechanical behavior of biofilms. (phys.org)
  • The model contributes to a better understanding of one of the resistant mechanisms in biofilms. (osu.edu)
  • Several parameters were included in the model (see Table S1 in the supplemental material), including estimated per-cell signal production rate, biofilm biomass accumulation, Fickian diffusion of signal in the biofilm, and assumed geometry of a flat, two-dimensional biofilm. (asm.org)
  • matrix
  • In Salmonella , cellulose is one of the major constituents of the biofilm matrix. (asm.org)
  • Whereas bacterial envelope proteins and fimbriae have been shown to play critical roles in this process, the production of an extracellular matrix is also recognized as a key element in determining the mature biofilm architecture ( 61 ). (asm.org)
  • Biofilms are generally a group of living organisms that have a protective matrix of metallo-mineral and organic molecule coating. (ndnr.com)
  • In most cases, the biofilm matrix is able to protect the organism colony from even the highest and strongest doses of antibiotic or other anti-infective drugs. (ndnr.com)
  • Infection
  • As an example, biofilms are often an underlying cause and impediment to cure in a person with a chronic infection. (ndnr.com)
  • potential
  • A simple PubMed search using the terms "biofilm" and "human" yields 14 417 publications - an indication of the breadth and depth of research on the potential effects of biofilms on human health and disease. (ndnr.com)
  • system
  • A growing biofilm requires anchoring, and in earlier research, this team, led by Jin, an Associate Professor of Rheumatology and Inflammation Research, the University of Gothenburg, Gothenburg, Sweden, had discovered that S. aureus hijacks the human clotting system to create a scaffold of micro-clots to support the growing biofilm. (phys.org)
  • Given readily accessible materials, detailed instructions and figures, and a finished flow cell system to observe, a student will be able to construct a simple flow cell system that is suitable for growing biofilms in square capillary tubing on the stage of a microscope. (montana.edu)
  • better
  • The medical relevance of biofilms in human illness is better understood now than ever before. (ndnr.com)
  • often
  • Although the subject of biofilms' impact on disease has been in the medical literature for quite some time, 2 significant limitations exist which often impede clinicians' understanding of not only their effect on disease progression and resistance but also their complexity. (ndnr.com)
  • support
  • However, the quantity of the biofilm formed was higher when polar surface groups were present on the support. (hindawi.com)