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  • injectable badger
  • There are both oral and injectable badger vaccines but applying these over large areas will always be both difficult and expensive. (bovinetb.co.uk)
  • We will then be able to make an application to the Veterinary Medicines Directorate for an Animal Test Certificate to begin the field trials proposed in EU Commissioner Tonio Borg's letter to the Secretary of State for Environment, Food and Rural Affairs dated 14 January 2013.An injectable badger vaccine was licensed in 2010. (bovinetb.co.uk)
  • cattle
  • Well, although cattle are regularly vaccinated for other diseases, there is an EU ban on TB vaccines. (bovinetb.co.uk)
  • We urgently need a modified cattle vaccine and then the guts to get the EU ban lifted both difficult objectives. (bovinetb.co.uk)
  • From his questions asked in parliament, Rob Marris MP has discovered that the development of a tuberculosis vaccine for cattle has been sacrificed in favour of a costly compensation scheme for farmers. (bovinetb.co.uk)
  • Mr Heath[holding answer 13 June We hope to have successfully completed all the cattle vaccine experimental work, including studies on safety of meat and milk, during 2014. (bovinetb.co.uk)
  • Tragic that the cattle vaccine with DIVA test to distinguish TB from vaccinated cows has been available nearly 15 years. (bovinetb.co.uk)
  • He said: My preference would be to use a cattle vaccine, but the European Union is preventing us from doing that," said Mr Wiggin, who is North Herefordshire's MP and runs a small herd of Hereford cattle at his farm near Ledbury. (bovinetb.co.uk)
  • trials
  • Combining data from 13 trials, fewer patients vaccinated with BCG developed TB than those not receiving the vaccine (Table). (acpjc.org)
  • dose
  • Dose-Escalation Study to Evaluate the Safety and Immunogenicity of MTBVAC Vaccine in Comparison With BCG Vaccine. (clinicaltrials.gov)
  • The study involves random allocation of up to 36 subjects (4 vaccine groups of 9 volunteers fulfilling the inclusion criteria) to MTBVAC (tested at three separate doses) or standard dose BCG (on a 3 verum : 1control basis) in a dose-escalation manner to one of three cohorts. (clinicaltrials.gov)
  • Each cohort includes 9 subjects set to receive MTBVAC lowest dose 5x10E03, or MTBVAC intermediate dose 5x10E04, or high dose 5x10E05 colony forming units (CFU) in 0.1 mL and 3 subjects set to receive standard dose BCG (5x10E05 CFU in 0.1 mL). (clinicaltrials.gov)
  • prevalence
  • BCG is used in many countries with a high prevalence of TB to prevent childhood tuberculous meningitis and miliary disease. (cdc.gov)
  • However, adults (up to the age of 35) who are frequently exposed to drug-resistant TB may also be given BCG vaccine.The global BCG vaccine market is driven by increase in prevalence of tuberculosis and rise in technological advancements in vaccine research. (medindia.net)
  • widely
  • BCG vaccine has been used widely in children, and it has not been reported to cause different side effects or problems in children than it does in adults. (drugs.com)
  • As the only TB vaccine, BCG has been in use since 1921,[ and is now the most widely used vaccine worldwide, with more than 3 billion total doses given. (clinicalcorrelations.org)
  • DIVA
  • If the work to enable deployment of the vaccine had been commenced at the same time as work began on the DIVA test it could have been deployed three years ago, four more years are expected to pass before its eventual deployment. (bovinetb.co.uk)
  • live
  • Immunotherapy with live BCG vaccine was shown to be an effective treatment as long ago as 1976, 1 and the vaccine is still the only intravesical agent to have been shown to reduce both of these risks. (bmj.com)
  • A person who has been treated with hepatitis B immune globulin should generally not be vaccinated for several months with a live vaccine. (drugs.com)
  • The treatment of the infectious complications of BCG requires long-term, multiple-drug antibiotic therapy and exposure to this live bacterium can be dangerous. (drugs.com)
  • The BCG was initially administered as a live oral vaccine. (clinicalcorrelations.org)
  • This powder-laden and dissolvable MNA represents a novel technology to sufficiently deliver live attenuated vaccine powders into the skin. (ovid.com)
  • complication
  • This complication carries a high mortality rate of 80-83%, and the incidence of fatality is estimated at 0.19-1.56 cases per 1 million vaccines given. (clinicalcorrelations.org)
  • This study confirms a high perioperative complication rate associated with the primary surgical treatment of BCG lymphadenitis in both HIV-positive and negative patients. (scielo.org.za)
  • adult
  • A randomized, double-blind, controlled Phase I study conducted at CHUV, Lausanne, Switzerland, to compare MTBVAC to licensed BCG in healthy, PPD-negative adult male and female volunteers. (clinicaltrials.gov)
  • reaction
  • The presence or size of a TST reaction in persons who have been vaccinated with BCG does not predict whether BCG will provide any protection against TB disease. (cdc.gov)
  • available
  • Ear-tagged, monitored and manageable they could be easily vaccinated so why aren't they, when a vaccine is available? (bovinetb.co.uk)
  • We are investing in the development of an oral badger vaccine but this work is still at the research stage and we cannot say with any confidence when a usable vaccine might become available. (bovinetb.co.uk)
  • infants
  • This route of administration was stopped in 1930 following the Lübeck (Germany) disaster, in which 27% of 249 infants receiving the vaccine developed and died from TB. (clinicalcorrelations.org)
  • immunity
  • 0.00001), it is hypothesized that exposure to certain endemic mycobacteria, thought to be more common in lower latitudes, might provide natural immunity to the indigenous people, and the addition of BCG vaccine does not add much to this natural protection. (clinicalcorrelations.org)
  • treatment
  • After bcg treatment how long before oral sex is ok? (drugs.com)
  • I don't know, but to tell you the truth it would be a longgggggggggg time before I had oral sex with someone who had bcg treatment. (drugs.com)
  • The BCG vaccine is not used in the US, where TB control emphasizes treatment of latently infected individuals. (clinicalcorrelations.org)
  • primary surgical treatment (incisional drainage or biopsy) is therefore not considered an ideal form of management in BCG lymphadenitis because of the high fistulisation and poor wound healing, especially in the HIV-positive patient. (scielo.org.za)
  • global
  • Untapped market potential in developing regions is expected to present numerous opportunities for market development.The global BCG vaccine market is segmented on the basis of demographics and country. (medindia.net)
  • A DNA BCG vaccine could be very important in the global fight against TB. (sciencephoto.com)