AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceHealth CareGeographicals
Acinetobacter baumanniiWound InfectionSurgical Wound InfectionWound HealingAcinetobacter InfectionsAcinetobacterSternumAnti-Bacterial AgentsCarbapenemsDrug Resistance, Multiple, BacterialColistinWounds and InjuriesNegative-Pressure Wound TherapyWounds, PenetratingSternotomyCross InfectionMicrobial Sensitivity TestsAcinetobacter calcoaceticusSurgical Wound DehiscenceMediastinitisSuturesImipenemBurnsSurgical SpongesAntibiotic Prophylaxisbeta-LactamasesDrug Resistance, Bacterialbeta-Lactam ResistanceSulbactamPostoperative ComplicationsDebridementSuture TechniquesPremedicationBites and StingsElectrophoresis, Gel, Pulsed-FieldTreatment OutcomeDNA, BacterialBandagesSurgical FlapsVibrio InfectionsAppendectomyThienamycinsMinocyclineRetrospective StudiesSkinVibrio vulnificusBacterial Typing TechniquesSuppurationWounds, StabBacterial ProteinsLength of StayCefazolinAbdominal AbscessSurgical MeshHospitalsMolecular TypingPseudomonas aeruginosaGram-Negative Bacterial InfectionsSkin CareOcclusive DressingsWound Closure TechniquesTherapeutic IrrigationPseudomonas InfectionsStaphylococcal InfectionsAnti-Infective Agents, LocalDisease OutbreaksSequence Analysis, DNAGranulation TissueIntensive Care UnitsDNA FingerprintingAppendicitisProspective StudiesAntisepsisDermatologic Surgical ProceduresUmbilicusBacteremiaOmentumBacterial InfectionsTime FactorsVacuumPolydioxanoneAdministration, TopicalMolecular EpidemiologyIntegronsMultilocus Sequence TypingGram-Negative BacteriaPovidone-IodineReoperationBiofilmsMolecular Sequence DataCardiac Surgical ProceduresHospital Design and ConstructionColostomyStaphylococcus aureusCyanoacrylatesPectoralis MusclesLaparotomySkin Diseases, BacterialSoft Tissue InfectionsInfection Control
Acinetobacter BaumanniiIsolatesPseudomonasBacteriaPneumoniaPathogenOpen woundsPathogensStaphylococcusPrevalenceColonizationAntibioticsResistance to carbapenemsAntimicrobialBloodstream InfectionsWorld Health OrganCathetersHospitalsAntibiotic-resistantAeruginosaCarbapenem resistanceCRABBiofilmICUsSevere infectionsColistin resistanceDiseasesResistantLungsSpeciesBurn woundsPatientsAureusOutbreaksRespiratoryMeningitisBacteriumSepsisSymptomsOpportunistic infectionsTherapeuticClinicalMicrobialPreventionHospital
Acinetobacter Baumannii49
Isolates13
  • This study determined the prevalence of MDR A. baumannii isolates from intensive care units in a large tertiary-care hospital in Ismailia, Egypt, and the occurrence of different beta-lactamases in these isolates. (who.int)
  • In the evaluation of its therapeutic potential against CRAB clinical isolates using two in vivo models, phage Βϕ-R2096 increased the survival rates of both G. mellonella larvae (from 0 to 50% at 24 h) and mice (from 30% with MOI = 0.1 to 100% with MOI = 10 for 12 days) in post-infection of CRAB. (biomedcentral.com)
  • However, imipenem-resistant isolates were found in the early 1990s [ 17 ], and the rate of carbapenem resistance in A. baumannii , mainly due to OXA-type (oxacillin-hydrolysing) carbapenemases, has increased rapidly [ 7 , 11 ]. (pfmjournal.org)
  • In South Korea, more than two-thirds of the A. baumannii isolates were resistant to imipenem on the basis of several surveillance studies [ 4 , 15 , 18 ]. (pfmjournal.org)
  • A. baumannii isolates (n = 83) originated from two hospital settings in central Ohio were used in this study. (biomedcentral.com)
  • Our phenotypic analysis clearly demonstrated that A. baumannii isolates obtained from different hospitals in central Ohio were resistant to all clinically significant antibiotics, including carbapenems (imipenem). (biomedcentral.com)
  • A. baumannii isolates (n = 83) that originated from two sources were investigated. (biomedcentral.com)
  • For Enterobacter infections caused by multidrug-resistant isolates, colistin (polymyxin E), a last-resort antibiotic, is a potential treatment option. (pataigin.com)
  • We showed previously that colistin heteroresistance can mediate the failure of colistin therapy in an in vivo infection model, even for isolates designated susceptible by clinical diagnostics. (pataigin.com)
  • It's really common now to find A. baumannii isolates that are resistant to nearly every antibiotic," Jonathan Stokes, a former MIT postdoc, said in a statement. (easterneye.biz)
  • The significance of Acinetobacter isolates from clinical specimens, such as respiratory secretions from intubated patients or specimens from open wounds, is difficult to determine because they often represent colonization. (msdmanuals.com)
  • On average, 21 hospitals as medical center/year participated in the survey, and 6803 A. baumannii isolates were identified. (jmedscindmc.com)
  • All isolates were health care-related infections. (jmedscindmc.com)
Pseudomonas7
  • These bacteriophages appear to be most similar to bacteriophages that infect Pseudomonas and Ralstonia rather than Enterobacteriales bacteria by protein similarity, however, we were only able to detect infection of Erwinia and the closely related strains of Pantoea . (frontiersin.org)
  • Their newest production discusses a bacterium known as Pseudomonas aeruginosa that can cause infections in the blood, lungs and potentially other parts of the body. (environmental-expert.com)
  • Pseudomonas aeruginosa is known to be a major cause of severe infections, including pneumonia, sepsis, wound and skin infections. (pall.com)
  • Pseudomonas aeruginosa wound infection involves activation of its iron acquisition system in response to fascial contact. (uchicago.edu)
  • Applying HClO CNFS/Ag NPs daily for 3 days and then cleansing with just pure water and covering with CNFS alone daily for 9 days were performed for Pseudomonas aeruginosa-infected wounds in db/db diabetic mice. (ewco.com)
  • Staphylococcus aureus and Pseudomonas aeruginosa were used for antimicrobial efficacy evaluation (based on DIN EN 13727). (ewco.com)
  • Klebsiella pneumoniae, Staphylococcus aureus, Pseudomonas and Proteus mirabilis are among the most important causes of nosocomial infections [10]. (jpmed.ir)
Bacteria17
  • The bacteria are multidrug-resistant, making infections very difficult to treat. (mn.us)
  • Complicated infections from multidrug-resistant Gram-negative bacteria (MDR-GNB) represent a serious problem presenting many challenges. (mdpi.com)
  • Although the first report of carbapenemases was registered with Enterobacteriaceae, the others Gram-nega- tive bacteria, such as A. baumannii and P. aeruginosa, can also produce this enzyme. (scirp.org)
  • It is a common bacteria in the environment meaning hosts can carry the virus without infection but can easily infect patients in a hospital. (rentokil-hygiene.co.uk)
  • Infection will normally begin in the lungs as the bacteria are inhaled or passed through a ventilator but it can be associated with a catheter infection. (rentokil-hygiene.co.uk)
  • There are many more ways to help cure infections, and we need to focus on them in the era of drug-resistant bacteria ," she added. (iflscience.com)
  • First up, A. baumannii (or "Iraqibacter", a reference to its association with troops wounded during the Iraq War), which shows resistance to the vast majority of frontline drugs - but , excitingly, not to white oak, whose application appeared to inhibit the growth of the bacteria. (iflscience.com)
  • While Acinetobacter as a broad class of bacteria is indeed found in soil, the particular species causing the epidemic among the troops, A. baumannii -- which has spread to and killed civilians in American and European military hospitals -- is not native to Iraqi soil, as the Pentagon has claimed and the press has repeated many times. (metafilter.com)
  • In other words, Iraqis didn't give us this bug -- we gave it to them, by creating conditions (i.e., massive amounts of wounded, unsterile conditions, and antibiotic overuse) in which the bacteria thrived and spread. (metafilter.com)
  • We found a significant enhancement of wound healing and a reduction of bacteria counts compared to the controls. (ewco.com)
  • A new type of antibiotic can effectively treat an antibiotic-resistant infection by disarming instead of killing the bacteria that cause it. (worldpharmatoday.com)
  • According to the U.S. Centers for Disease Control and Prevention, at least 23,000 people die each year in the U.S. from infections caused by resistant bacteria. (biopharmabusiness.com)
  • Prescribing antibiotics is the first way to treat the disease due to the important role of bacteria in causing nosocomial infections but the challenge in the treatment of these infections is the occurrence of antibiotic resistance [11]. (jpmed.ir)
  • AIM(s) In this study, frequency and risk factors and antibiotic resistance of nosocomial infections caused by gram positive bacteria were investigated during 6 years in Mustafa Khomeini Hospital in Iran RESEARCH TYPE The present study is a retrospective cross -sectional and descriptive analytical study. (jpmed.ir)
  • METHOD The information required for each patient (based on the Clinical Guidebook of nosocomial Infection in Iran) in the information form including: age, gender, hospitalization department, performing invasive procedures (endotracheal intubation, cathetering, venous catheter, arterial catheter) culture samples, sensitivity and resistance to antibiotics, type of antibiotic, type of infection and type of bacteria were recorded. (jpmed.ir)
  • Infections from the drug-resistant Shigella bacteria , often resulting in severe diarrhea and stomach pain, have been climbing at an alarming rate, too. (feedimo.com)
  • Conclusion High number of resistant microorganisms was isolated, and increased mortality was documented from infections caused by carbapenem-resistant bacteria. (who.int)
Pneumonia8
  • The treatment depends on the area of infection for example if you have pneumonia, you may need oxygen and medicines to help you breathe. (rentokil-hygiene.co.uk)
  • In this study, a novel A. baumannii lytic phage, the YMC 13/03/R2096 ABA BP (phage Βϕ-R2096), which specifically causes the lysis of CRAB strains, was characterized in detail in vitro and in silico, and the in vivo effectiveness of phage therapy was evaluated using Galleria mellonella and a mouse model of acute pneumonia. (biomedcentral.com)
  • This study is the first report to compare in vivo evaluations ( G. mellonella larvae and a mouse acute pneumonia model) of the therapeutic efficacy of a phage against CRAB infections. (biomedcentral.com)
  • followed by pneumonia 21.7% (5/130), 17.4% (4/130) surgical site infection, 13.0% (3/130) gastroenteritis, 13.0% (3/130) blood stream infection and meningitis. (amhsr.org)
  • 5 ] According to published literature the most prevalent nosocomial infections among patients in ICU are urinary tract infection (UTI), pneumonia, bloodstream infections, skin and soft tissue infections, gastroenteritis, hepatitis and central nervous system infections like meningitis. (amhsr.org)
  • Acinetobacter causes a variety of diseases, ranging from pneumonia to serious blood or wound infections, and the symptoms vary depending on the disease. (outbreaknewstoday.com)
  • This bacterium is commonly found in hospitals and can lead to severe infections like pneumonia and meningitis, making it a significant concern for healthcare settings and wounded soldiers. (easterneye.biz)
  • Community-acquired infections (mostly pneumonia) are more common in tropical climates. (msdmanuals.com)
Pathogen2
  • A. baumannii has become a representative pathogen that threatens human health. (pfmjournal.org)
  • Multidrug-resistant Acinetobacter baumanii is a major pathogen encountered in pyogenic infections, especially from burns patients in hospital settings. (medbc.com)
Open wounds6
  • In the present analysis, we researched the 535 botanical drugs included in the Chinese pharmacopeia and identified 183 medicinal plant species, 82 for treating open wounds caused by trauma and 101 for inflammatory skin conditions. (thieme-connect.de)
  • It can also live in a patient without causing infections or symptoms- this is especially common in open wounds and respiratory secretions. (sterifre.com)
  • Acinetobacter may also "colonize" or live in a patient without causing infection or symptoms, especially in tracheostomy sites or open wounds. (outbreaknewstoday.com)
  • Hospitalized patients, especially very ill patients on a ventilator, those with a prolonged hospital stay, those who have open wounds, or any person with invasive devices like urinary catheters are also at greater risk for Acinetobacter infection. (outbreaknewstoday.com)
  • A baumannii can infect hospitals, nursing homes, and patients who need ventilators and blood catheters, as well as those who have open wounds from surgeries. (ibtimes.sg)
  • These pathogens can cause a range of potentially severe infections in the lungs, urinary tract, ears, blood, open wounds, or even the brain and the spinal cord. (feedimo.com)
Pathogens9
  • Saiman L, Siegel J. Infection control recommendations for patients with cystic fibrosis: microbiology, important pathogens, and infection control practices to prevent patient-to-patient transmission. (cdc.gov)
  • When this barrier is damaged, pathogens can directly infiltrate the body, resulting in infection. (medscape.com)
  • Fungal pathogens also can infect burn wounds. (medscape.com)
  • Among the fungal pathogens, Candida albicans is the most common cause of infection. (medscape.com)
  • The World Health Organization lists A. baumannii in their highest category of pathogens posing an imminent threat to human health. (health.mil)
  • Comprehensive panel detecting, by Molecular Technique, the most common pathogens infecting wounds and soft skin. (syncierbiotech.com)
  • The frequency of clinical infection caused by these pathogens is low in LTCFs (77, 78). (cdc.gov)
  • The Infectious Diseases Society of America (IDSA) identified A. baumannii among the top seven pathogens threatening our healthcare-delivery system and as a crucial example of unmet medical need [ 18 ]. (biomedcentral.com)
  • Separately, or together, these effects may increase host susceptibility to infection by introduced pathogens. (biomedcentral.com)
Staphylococcus2
Prevalence6
  • Despite the low prevalence of A. baumannii infection in this hospital, the antibiotic resistance profile suggests that prevention of health-care-associated transmission of MDR Acinetobacter spp. (who.int)
  • The identification and characterization of Gram-negative microorganisms with resistance patterns to antimicrobials may improve the management of sources and spreading, enabling plans infection control measures plans in settings with important prevalence of these microorganisms. (scirp.org)
  • ICUs, especially those at tertiary care facilities, may have a higher prevalence of MDRO infections than do non-ICU settings (73, 74). (cdc.gov)
  • Assessing the prevalence and antibiotic resistance patterns of Neisseria gonorrhoeae in sexually transmitted infections. (dissertation-help.uk)
  • Hence, the objective of the present study is to know the prevalence and nature of nosocomial infections in ICU of a government district hospital. (amhsr.org)
  • This is the first report on the prevalence of health care-related A. baumannii infection in Taiwan in 2008-2019. (jmedscindmc.com)
Colonization4
  • Biofilm production facilitates microbial colonization of wounds and catheters. (bvsalud.org)
  • This resulted in an investigation that identified 34 patients with hospital-acquired multidrug-resistant CRAB infection or colonization from February to July 2020. (sterifre.com)
  • Analyzing the impact of prolonged hospitalization and interventions on microbial colonization and infections in COVID-19 patients. (dissertation-help.uk)
  • Mice were treated with either ciprofloxacin, penicillin, or water (control) for a 5-day period followed by a 5-day washout period prior to oral challenge with C. jejuni or A. baumannii to assess antibiotic effects on colonization susceptibility. (biomedcentral.com)
Antibiotics8
  • These infections more frequently occur after the use of broad-spectrum antibiotics. (medscape.com)
  • One of the primary concerns associated with burn injuries is the avascularity of eschar, preventing immune cells and systemically administered antibiotics from being delivered to the infection site. (medscape.com)
  • Carbapenems have been the most effective antibiotics against the serious infections caused by Acinetobacter spp. (biomedcentral.com)
  • Although β-lactam antibiotics are the preferred choice for susceptible A. baumannii infections, carbapenems have become the main therapeutic option because of an increase in resistance [ 2 , 6 ]. (pfmjournal.org)
  • Strains of A. baumannii have acquired resistance to a wide range of antibiotics, and some are resistant to every FDA-approved antibiotic, making them untreatable. (worldpharmatoday.com)
  • Since the use of antibiotics in various infections has increased, examining antibiotic resistance is a research priority in each region. (jpmed.ir)
  • Preliminary data from the report, released by the WHO this month, paint a dire picture: Just 27 new antibiotics for the most threatening infections are in the clinical trial stage of drug development. (feedimo.com)
  • In February, the CDC warned that last year, 5% of Shigella infections were "extensively drug-resistant" - meaning they didn't respond to a number of antibiotics - up from zero percent in 2015. (feedimo.com)
Resistance to carbapenems2
  • Also, a 3-month survey of 15 Brooklyn hospitals in 1999 found that 53% of A. baumannii strains exhibited resistance to carbapenems and 24% of P. aeruginosa strains were resistant to imipenem (10). (cdc.gov)
  • Increasing resistance to carbapenems in A. baumannii has been observed worldwide. (shengsci.com)
Antimicrobial5
  • Our research might one day benefit modern wound care, if we can identify which compounds are responsible for the antimicrobial activity," adds Micah Dettweiler, the first author of the paper. (labmanager.com)
  • It is imperative that all healthcare providers are cognizant of and learn the stewardship of the dwindling inventory of effective antimicrobial drugs given the rising global spread of antibiotic drugs resistance and incidence of hospital- and community-acquired infections. (cedevelopment.org)
  • We have previously reported a study of developing antimicrobial biomaterials made up of chitin-nanofiber sheet (CNFS) -immobilized silver nanoparticles (CNFS/Ag NPs) and showed that either cleansing with HClO or covering with CNFS/Ag NPs daily for more than 7 days resulted in delayed wound healing. (ewco.com)
  • To determine the cytotoxicity and antimicrobial efficacy of six NaClO/HClO wound irrigation solutions. (ewco.com)
  • Three bundled programmes will be sequentially implemented after a minimum 6-month baseline monitoring period - microbiology and diagnostic stewardship (MDS), infection prevention and control (IPC), and antimicrobial stewardship (ABS). (who.int)
Bloodstream Infections2
  • The bacterium can cause potentially lethal bloodstream infections. (worldpharmatoday.com)
  • Apart from causing bloodstream infections, it can also lead to infections in the urinary tract and lungs. (citytelegraph.com)
World Health Organ2
  • In 2011, the World Health Organization (WHO) reported that 63,000 patients die each year in US hospitals and 25,000 patients lose their lives annually in the European Union due to antibiotic-resistant infections. (cedevelopment.org)
  • It is a member of the ESKAPE group, which is the main bacterial group that causes infections in humans [ 12 ], and has been recently ranked as a bacterium that poses the greatest health threat by World Health Organization [ 13 ]. (pfmjournal.org)
Catheters1
  • Healthcare facilities, including hospitals and nursing homes, are particularly vulnerable to this bacterium, as it poses a risk to patients who require ventilators, blood catheters, or have surgical wounds. (citytelegraph.com)
Hospitals3
  • That is promising stuff - as Quave points out, A. baumannii is " emerging as a major threat for soldiers recovering from battle wounds and for hospitals in general. (iflscience.com)
  • Although the Intensive Care Units (ICUs) account for fewer than 10% of total beds in most hospitals, more than 20% of all nosocomial infections are acquired in ICUs. (amhsr.org)
  • In fact, A. baumannii is found most often in hospitals, particularly in ICUs. (metafilter.com)
Antibiotic-resistant1
  • Investigating the potential of phage therapy for the treatment of antibiotic-resistant respiratory tract infections. (dissertation-help.uk)
Aeruginosa1
  • The relationship between antibiotic resistance and virulence factors observed in this study could play an important role in outbreaks associated with P. aeruginosa infections. (ophrp.org)
Carbapenem resistance1
  • Several invasive diseases, such as urinary tract infections, are associated with higher rates of carbapenem resistance. (jmedscindmc.com)
CRAB5
  • In particular, carbapenem-resistant A. baumannii (CRAB) strains have been increasing in the past decade, and they have caused major medical problems worldwide. (biomedcentral.com)
  • The A. baumannii phage Βϕ-R2096 was isolated from sewage water using CRAB clinical strains selected from patients at a university hospital in South Korea. (biomedcentral.com)
  • The results of this study strongly suggest that phage Βϕ-R2096, a novel A. baumannii lytic phage, could be an alternative antibacterial agent to control CRAB infections. (biomedcentral.com)
  • On May 28, 2020, an anonymous 500-bed New Jersey hospital reported a cluster of CRAB infections during a surge in patients hospitalized with coronavirus (COVID-19). (sterifre.com)
  • This study determined the number of infection sites of A. baumannii and the resistance rates of carbapenem-resistant A. baumannii (CRAB) infections in ICUs in Taiwan, and identified trends over time, variations of infection site, and factors associated with resistance. (jmedscindmc.com)
Biofilm7
  • Candida albicans is another strong biofilm producer which may facilitate A. baumannii adhesion by providing hyphae-mediated OmpA-binding sites. (bvsalud.org)
  • Here we tested the potential of 2'-hydroxychalcones to inhibit dual-species biofilm production of A. baumannii and Candida spp. (bvsalud.org)
  • A. baumannii dual-species biofilm production. (bvsalud.org)
  • The most effective in the presence of biofilm was ClHO at 1500 mg/L. ClHO at mediumlow concentrations (300 or 500 mg/L) is a good antiseptic that can be used on wounds and mucous membranes for 510 min. (ewco.com)
  • Biofilm formation causes prolonged wound infections due to the dense biofilm structure, differential gene regulation to combat stress, and production of extracellular polymeric substances. (ewco.com)
  • This work describes a novel wound dressing in the form of an electrochemical scaffold (e-scaffold) that generates controlled, low concentrations of hypochlorous acid (HOCl) suitable for killing biofilm communities without substantially damaging host tissue. (ewco.com)
  • The described strategy may provide a novel antibiotic-free strategy for treating persistent biofilm-associated infections, such as wound infections. (ewco.com)
ICUs2
  • Background: Patients in Intensive Care Units (ICUs) are a significant subgroup of all hospitalized patients, accounting for about a quarter of all hospital infections. (amhsr.org)
  • Few studies from Taiwan have used national-level data to investigate antibiotic resistance rates of A. baumannii infections in the intensive care units (ICUs) of medical centers. (jmedscindmc.com)
Severe infections1
  • including A. baumannii , have long been known as colonizers in humans, but they do not cause severe infections [ 10 ]. (pfmjournal.org)
Colistin resistance3
Diseases2
  • Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America. (cdc.gov)
  • Other common diseases are urinary tract infections, wound infections, and sepsis. (acinetobacterbaumannii.com)
Resistant11
  • [ 7 ] More recently, a trend toward nosocomially acquired, intrinsically resistant fungal infections (eg, Candida krusei ) has been reported. (medscape.com)
  • Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (who.int)
  • Colistin (in Germany not commercially available) is used for treating infections caused by pan-resistant strains. (acinetobacterbaumannii.com)
  • The new generation of resistant infections is almost impossible to treat. (metafilter.com)
  • This study underscores the major role of carbapenem-hydrolyzing class D β-lactamases, and in particular the acquired OXA-23, in the dissemination of imipenem-resistant A. baumannii . (biomedcentral.com)
  • Here we report the clinical impact and mechanism of imipenem heteroresistance (imipenem minimum inhibitory concentration of 6-32 μg/mL with the presence of resistant cells inside the inhibition zone of Etest strips or disks) in multidrug-resistant A. baumannii (MDR-AB). (shengsci.com)
  • Eventually, they identified a drug called abaucin, which effectively treated wound infections caused by A. baumannii and exhibited activity against several drug-resistant infections. (easterneye.biz)
  • While the experimental data acquisition is ongoing, the findings so far offer promising prospects for addressing multidrug-resistant bacterial infections, especially those caused by Acinetobacter. (easterneye.biz)
  • Also, the number of multidrug-resistant AB infections has increased in service members who were injured and treated in Iraq, Kuwait, and Afghanistan. (msdmanuals.com)
  • But the infection, a drug-resistant strain of E. coli, surged on. (feedimo.com)
  • In the United States alone, the Centers for Disease Control and Prevention estimates more than 2.8 million people develop drug-resistant infections each year, and more than 35,000 people die as a result. (feedimo.com)
Lungs1
  • In addition to blood infections, A baumannii can cause infections in urinary tracts and lungs. (ibtimes.sg)
Species3
  • Resources of the Southern Fields and Forests," published in 1863, was a major compendium of uses for different plants, including a description of 37 species for treating gangrene and other infections. (futurity.org)
  • Further, higher OmpA-binding affinity was also calculated for p-CF3, which together with demonstrated significant ompA-downregulating activity, suggests that superior antibiofilm activity of this chalcone against the tested dual-species community of A. baumannii is mediated through the OmpA. (bvsalud.org)
  • After further screening for reports on the presence of known photoactive compounds, we determined a core group of 10 scientifically lesser-known botanical species that may potentially be developed into more widely used topical preparations for photodynamic treatment of infected wounds. (thieme-connect.de)
Burn wounds1
  • [ 1 ] Unlike other types of injury, burn wounds induce metabolic and inflammatory alterations that predispose the patient to various complications. (medscape.com)
Patients15
  • Recommendations for Preventing Transmission of Infections Among Chronic Hemodialysis Patients. (cdc.gov)
  • Through the Daly team's efforts, a protective vaccine has been developed that could potentially prevent battlefield infections, as well as hospital-acquired infections in patients going in for routine surgery. (health.mil)
  • Infections caused by this virus tend to occur in patients with an underlying disease. (rentokil-hygiene.co.uk)
  • Exploring the microbial co-infections in COVID-19 patients and their impact on disease severity. (dissertation-help.uk)
  • Aim: The aim was to study, the current status of nosocomial infection, rate of infection and distribution of infection among patients admitted in Medical Intensive Care Unit (MICU) of a District Hospital. (amhsr.org)
  • Results: Incidence of nosocomial infections in MICU patients was 17.7% (23/130). (amhsr.org)
  • Conclusion: The most frequent nosocomial infections (urinary, respiratory, and surgical site) were common in geriatric patients in the MICU setting and are associated with the use of invasive device. (amhsr.org)
  • 1 ] These infections are opportunistic, and microorganisms of low virulence can also cause disease in hospital patients whose immune mechanisms are impaired. (amhsr.org)
  • Outbreaks of Acinetobacter infections typically occur in intensive care units and healthcare settings housing very ill patients. (outbreaknewstoday.com)
  • Continuous versus intermittent infusion of cefepime in neurosurgical patients with post-operative intracranial infections. (shengsci.com)
  • AB infections typically occur in critically ill, hospitalized patients. (msdmanuals.com)
  • RESEARCH SOCIETY, PLACE & TIME This study was conducted on patients with the diagnosis of nosocomial infection during the years 2014 to 2019 at Shahid Mustafa Khomeini Hospital in Tehran, Iran. (jpmed.ir)
  • SAMPLING METHOD AND NUMBER Based on the census sampling method, 263 patients were identified by diagnosing infection at the time of the study (4 people have two different nosocomial infections and 2 have a common nosocomial infection with different risk factors). (jpmed.ir)
  • Late last year, one of Dr. Vance Fowler's patients - a man in his 60s who'd returned to North Carolina from visiting his family in Nepal - died of a bacterial infection. (feedimo.com)
  • 2023. Data from all hospitalized patients with culture-confirmed infection were analyzed. (who.int)
Aureus1
  • Next, S. aureus , widely considered to be the most dangerous common staph infection. (iflscience.com)
Outbreaks1
  • The links between casualties brought back from Iraq and outbreaks in the NHS have caused alarm within the health service and led to renewed demands for more dedicated wards for Britain's armed forces to enable wounded soldiers to be isolated more effectively. (sott.net)
Respiratory2
  • Nosocomial respiratory syncytial virus infections: the "Cold War" has not ended. (cdc.gov)
  • Evaluating the microbial composition of respiratory tract infections in immunocompromised individuals. (dissertation-help.uk)
Meningitis1
  • The virus can cause severe central nervous system infections, meningitis and ventriculitis. (rentokil-hygiene.co.uk)
Bacterium1
  • The researchers believe that the unique lipoprotein trafficking mechanism of A. baumannii makes abaucin specifically effective against this bacterium, giving it a narrow spectrum of activity. (easterneye.biz)
Sepsis2
  • New strategies need to be found to combat infection and sepsis in the burn ICU. (qmul.ac.uk)
  • and explores for the presence of the cathelicidin, LL-37 in the burn wound and examines it potential utility for treating infection and sepsis. (qmul.ac.uk)
Symptoms1
  • Subjects and Methods: Data were collected retrospectively from 130 patient's records presented with symptoms of nosocomial infection in MICU of a Tertiary Health Center, Tumkur from August 2012 to May 2013. (amhsr.org)
Opportunistic infections1
  • Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. (cdc.gov)
Therapeutic2
  • baumannii, the therapeutic possibilities of which should be proved in future in vivo studies. (bvsalud.org)
  • In the era of increasing antibiotic resistance it may provide a novel therapeutic role in treating MRAB infection. (qmul.ac.uk)
Clinical2
Microbial2
  • This undermines the effectiveness of the available treatment options and thus contributes to the persistence of microbial infections. (who.int)
  • Studying the microbial transmission dynamics within households post-COVID-19 infection. (dissertation-help.uk)
Prevention5
  • Factors associated with improved outcome and infection prevention include early burn eschar excision, topical antibiotic therapy, and aggressive infection-control measures. (medscape.com)
  • As a result, it was not possible for staff to follow conventional infection prevention and control practices. (sterifre.com)
  • However, in late May as COVID-19 hospitalizations decreased, the New Jersey hospital resumed normal operation and were able to follow standard infection prevention protocols. (sterifre.com)
  • Largeâ  scale studies are needed to be carried out in Indian population to plan longâ  term strategies for prevention and management of nosocomial infections. (amhsr.org)
  • Sodium hypochlorite (NaClO, SHC)/hypochlorous acid (HClO, HCA) wound irrigation solutions have experienced a renaissance in the prevention and treatment of low-level wound infections. (ewco.com)
Hospital16
  • The Hospital Infection Control Practices Advisory Committee. (cdc.gov)
  • Bent S, Shojania KG, Saint S. The use of systematic reviews and meta-analyses in infection control and hospital epidemiology. (cdc.gov)
  • It is crucial that the infection control and PPE supply chain becomes more reliable, to relieve some of the pressure from hospital staff and help combat MDROs. (sterifre.com)
  • Analyzing the effectiveness of infection control measures in reducing healthcare-associated infections in a tertiary care hospital. (dissertation-help.uk)
  • Infections in critical care unit are high, and of serious hospital problems. (amhsr.org)
  • Infections acquired during the hospital stay are generally called nosocomial infections, initially known as infections arising after 48 h of hospital admission. (amhsr.org)
  • 1 , 2 ] National Nosocomial Infections Surveillance system defines a nosocomial infection as a localized or systemic condition that results from adverse reaction to the presence of an infectious agent (s) or its toxin (s) that was not present or incubating at the time of admission to the hospital. (amhsr.org)
  • Hospital acquired infections involves yearly about 2 millions in US and accounts approximately for a cost of 4.5 billion dollars. (amhsr.org)
  • Even though, it is not possible to eradicate the nosocomial or hospital acquired infections entirely, many of them can be prevented by proper control measures. (amhsr.org)
  • Ten days in hospital, a month of twice-daily wound-cleaning after the hospital, plus I was the only one at my pharmacy with a prescription for Cipro that wasn't taking it 'cause I was scared of Terrorist Anthrax. (metafilter.com)
  • It has now become a major cause of hospital-acquired infections worldwide due to its remarkable propensity to rapidly acquire resistance determinants to a wide range of antibacterial agents [ 2 ]. (biomedcentral.com)
  • The Department has ordered a Directed Plan of Correction that requires University Hospital to employ a full-time Certified Infection Control Practitioner consultant, who will report to the Department on immediate actions taken in the coming days. (outbreaknewstoday.com)
  • Yearly, Taiwan Nosocomial Infections Surveillance System Surveys from 2008 to 2019 were analyzed, including data on the site of infection and resistance rates of A. baumannii and patient and hospital characteristics. (jmedscindmc.com)
  • Among the experts' and WHO's most pressing concerns were how deadly the infections were, whether treatment required a long hospital stay and how many current medicines exist. (biopharmabusiness.com)
  • Nosocomial infections is one of the problems of hospital environments, which in addition to economic costs, sometimes prolongs the patient's hospitalization [1]. (jpmed.ir)
  • We conducted a study on burn wound pus samples obtained from the burns unit of our hospital. (medbc.com)