Basic biophysical processes. Medical search. Frequent questions

To dissect the mechanics of translation initiation, Lorsch and collaborators developed a yeast-based system and a wide variety of biochemical and biophysical methods. (nih.gov)

Prior to his appointment at NIGMS, Dr. Berg directed the Institute for Basic Biomedical Sciences at the Johns Hopkins University School of Medicine in Baltimore, where he also served as professor and director of the Department of Biophysics and Biophysical Chemistry. (upmc.com)
Lorsch came to NIGMS from the Johns Hopkins University School of Medicine, where he was a professor in the department of biophysics and biophysical chemistry. (nih.gov)
The Chemical Biology Thematic Research Group is engaged in a diverse range of research topics, which span structural biology, enzymology, nucleic acid research, signalling pathways, single-molecule biophysics, and biophysical chemistry of living tissues. (mcgill.ca)
The research interests of the members of the Chemical Physics Thematic Research Group are diverse, with groups focusing on high-end laser and NMR spectroscopies, kinetics and modelling of atmospheric chemical reactions, experimental and theoretical biophysical chemistry, polymers at interfaces, and statistical and quantum mechanics. (mcgill.ca)
In the field of biophysical chemistry, single molecule spectroscopy is being used to probe enzyme function as well as DNA recombination and repair. (mcgill.ca)
In the area of atmospheric chemistry, the chemical transformation of the atmosphere is being modelled both experimentally and theoretically to understand how these processes are currently affecting and driving climate change. (mcgill.ca)

More physicists should be encouraged to become active in research and development in the growing application fields of biophysics including molecular genetics, biomedical imaging, tissue generation and regeneration, drug development, prosthetics, neural and brain function, kinetics of nonequilibrium open biological systems, metabolic networks, biological transport processes, large-scale biochemical networks and stochastic processes in biochemical systems to name a few. (aps.org)
This project is embedded in the already brilliant Muscle Biophysics section of the Randall Centre for Cell & Molecular Biophysics, who harness cutting edge biophysical methodology for their experiments in additional to conventional modern biological techniques. (kcl.ac.uk)

Basic principles of modern biophysical and structural methods used to interrogate macromolecules from the atomic to cellular levels, including light and electron microscopy, X-ray crystallography, NMR spectroscopy, single molecule techniques, circular dichroism, surface plasmon resonance, mass spectrometry, and molecular dynamics and systems biological simulations. (caltech.edu)
This proposal suggests a combined cell biological and biophysical approach to elucidate the molecular and mechanical principles underlying such plasticity. (europa.eu)
The course covers the basics, principles and limitations for the most common methods for multivariate statistics (analysis of variance, principal component analysis and partial least squares regression), experimental design (super-saturated and factorial designs) and method validation with a focus on practical use. (lu.se)

The overall goal of this proposal is to apply our diverse suite of genetic, molecular, and biophysical tools to gain mechanistic insights into normal sperm chromatin packaging, which is essential for genome fidelity and reproductive fitness of the species. (hhs.gov)
Lectures and recitation introducing the molecular basis of life processes. (caltech.edu)
Lectures and recitation introducing the molecular basis of life processes, with emphasis on the structure and function of proteins. (caltech.edu)
Our laboratories use biophysical, electrophysiological, molecular biological and histological methods to determine fundamental molecular mechanisms by which neurotransmitters are released from primary sensory cells ('hair cells') to excite second order neurons carrying information to the brain. (hopkinsmedicine.org)
Understanding the structure and dynamics of the muscle sarcomere, the small molecular machines that power heart and skeletal muscles, at unprecedented detail will boost our understanding of fundamental muscle biology and allow analysing processes like ageing and muscle diseases with previously unknown insight. (kcl.ac.uk)
Basic concepts of colloid science like the surface force issue has wide applications in biochemistry and molecular biology. (lu.se)

Biophysical/Structural Methods. (caltech.edu)
While the structures of the different domains have been solved, minimum structural and biophysical studies have been performed on the C-terminal tails. (wustl.edu)

However, the basic function of the perceptron, a linear summation of its inputs and thresholding for output generation, highly oversimplifies the synaptic integration processes taking place in real neurons. (biorxiv.org)
Various processes such as facilitation and depression alter effective synaptic strength over time scales similar to those of normal activity. (jneurosci.org)

Several cellular radioprotection mechanisms may be involved, such as alterations in the levels of some cytoplasmic and nuclear proteins and increased gene expression, DNA repair and other processes. (wikipedia.org)
This motility is involved in basic cellular processes such as organelle trafficking, and in more specialized functions such as the transport of vesicles along the extended axonal processes of the neuron. (nih.gov)
Dynein function is essential in higher eukaryotes, yet its basic mechanisms of action including coupling to cargo and cellular regulation remain to be determined. (nih.gov)
As knowledge of such topics as cellular processes and complex ecological systems advances, researchers have found that progress in understanding these and other systems requires application of more quantitative approaches. (aps.org)
These proteins are part of elaborate networks that interact with a myriad of other molecules to effect diverse signaling pathways and affect cellular processes such as migration, apoptosis, cell differentiation and so on. (wustl.edu)
Here we consider the example of monolayer growth in-vitro to illustrate how in a multi-step process starting from an single-cell based off-lattice-model that subsumes the information on the sub-cellular scale by characteristic cell-biophysical and cell-kinetic properties a cellular automaton may be constructed whose rules have been chosen based on the findings in the off-lattice model. (mpg.de)

It explains the basic concepts of protein structure and function, enzyme kinetics, energy metabolism and basic biosynthetic pathways. (lu.se)
Compared to non-living systems, living organisms have more complex biochemical processes, which can be comprehended by studying the most important metabolic pathways and their control mechanisms. (lu.se)
Asserting the right to participate in landscape production and thus to help steer landscape along desirable development pathways remains a core component of landscape politics and grows in importance as many societies experience widespread citizen withdrawal from engagement in political processes. (lu.se)

Research and education address theoretical and methodological basics of environmental development and risk management. (tu-dresden.de)

Using a modular approach to teaching sport and exercise science, Biophysical Foundations of Human Movement, Third Edition , offers students a structured understanding of how the subdisciplines work independently and in tandem. (humankinetics.com)
The group will solve the structure of the sarcomere at near-atomic resolution, unravel the fundamentals of its force-driven assembly and turnover in health and ageing, and develop the foundations for future basic and translational research including the design and development of new agents to mitigate muscle disease and ageing. (kcl.ac.uk)

The method has great potential for a wide range of applications in basic biological and biophysical research. (nanotech-now.com)
This institute is one of our most far-reaching basic and clinically applicable research efforts," said Arthur S. Levine, M.D. , senior vice chancellor for the health sciences and dean, School of Medicine. (upmc.com)
In this position, Lorsch oversees all of the Institute's mission-related activities, supporting basic research that increases understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. (nih.gov)
In addition to moving into basic research in these areas, there is increasing opportunity for physicists in industry beginning with entrepreneurial roles in taking research results out of the laboratory and in the industries who perfect and market the inventions and developments that physicists produce. (aps.org)
In this talk we will identify and discuss emerging opportunities for physicists in biophysical and biotechnological pursuits ranging from basic research through development of applications and commercialization of results. (aps.org)
The epidermal growth factor receptor and its three orthologues, HER2, HER3 and HER4 have been the subject of intensive basic, clinical and translational research due to their involvement in cancers. (wustl.edu)
The research profile is the development and application of label-free optical biosensors, the mathematical modeling of the relevant biological and biophysical processes. (hun-ren.hu)
Our results can find further applications in basic biological and biophysical research, biotechnology and medical diagnostics. (hun-ren.hu)
This technique is applied both to basic biophysical research and development of drugs and therapeutics. (ubc.ca)

This paper presents the results of evaluation of possible biophysical methods and approaches for registering of various non-ionizing radiation (NIR) wave types of the human body in the electromagnetic range after the influence of device ABIEM (Akszjonovics, 2006). (oaji.net)

Studying aggregate internalization, however, is often hampered by the complex kinetics of the aggregation process, resulting in the concomitant uptake of aggregates of different sizes by competing mechanisms, which makes it difficult to isolate pathway-specific responses to aggregates. (ugent.be)
The mechanisms of developmental bioelectricity - the ability of all cells to form electrical networks that process information - suggests a plausible set of gradual evolutionary steps that naturally lead from physiological homeostasis in single cells to memory, prediction, and ultimately complex cognitive agents, via scale-up of the drive of infotaxis. (philpapers.org)
While much is known about biochemical signaling, many of the mechanisms that drive cell outcome in response to biophysical influences remain to be uncovered. (5dok.org)
A commonly used tool to study basic control mechanisms are in-vitro experiments in which the growth conditions can be widely varied. (mpg.de)

The second is the essential eukaryotic process of protein glycosylation by which sugars are added specifically to proteins. (caltech.edu)

From this, the central role of the heart is explored in terms of biochemical, biophysical and energetic interactions. (heartmath.org)
Heart relaxation also stands out as an active process, dependent on the energetic output and on specific ion and enzymatic actions, with the role of sodium channel being outstanding in the functional process. (bvsalud.org)

Here we have investigated biophysical regulation of cell function. (5dok.org)
Functional states of the sodium channel (closed, open, and inactivated) and their structure help to understand the cardiac regulation processes. (bvsalud.org)

A world-renowned bioinorganic chemist, Dr. Berg investigates the processes by which biomolecules interact with one another inside cells using both experimental and computational methods. (upmc.com)
The candidate is expected to have experience in basic microbiology methods, animal infection studies. (fems-microbiology.org)
The practical elements aim at giving the participants basic knowledge in selecting and applying methods for different applications. (lu.se)

At the LP3 crystallisation and biophysical laboratory, you can carry out a wide variety of robot-assisted crystallisation experiments in nano volumes as well as screen for a large number of buffer conditions to stabilize their sample. (lu.se)

The team of researchers have been awarded a Synergy Grant to determine the high-resolution structure of sarcomeres, the basic unit that makes up muscles. (kcl.ac.uk)

Using the perspective of another clinical application, there's a dire have to boost and standardize cryopreservation and basic safety examining before using frozen-thawed TT of TCSs for fertility recovery. (iassist2012.org)
The BPP is a clinical tool that integrates levels of dynamic biophysical activities into a usable standard. (medscape.com)

These communication networks are examined from an information processing perspective and reveal a fundamental order in heart-brain interactions and a harmonious synchronization of physiological systems associated with positive emotions. (heartmath.org)

It investigates the chemical substances and processes that occur within plants, animals and microorganisms at all levels of organ. (bookrags.com)

Also biophysical models presented general basics for this phenomenon. (wikipedia.org)
She then ran a second set of models that incorporated indicators of human interventions - such as input use and crop insurance - that alter biophysical conditions to support cultivation. (newfoodmagazine.com)
Unlike traditional gap models, LPJ-GUESS employs process-based representations of canopy gas exchange, plant resource use, growth and phenology, soil biogeochemistry and ecosystem hydrology. (lu.se)
To contribute to discussions of rural gentrification, this study present a case study in which agricultural landscape can act as a replacement of natural amenities and create a similar process of landscape- specific gentrification models in the countryside. (lu.se)

The results obtained with the DNA-PAINT method revealed that variations in several physical parameters - such as the overall speed of structure formation - have little influence on the overall quality of the assembly process. (nanotech-now.com)
and (3) it should be possible to relate parameters extracted from fitting the data to the underlying biophysical processes governing the behavior of the synapse. (jneurosci.org)
Specifically, the statistics of the stimulus spike trains are restricted, and the method uses multivariable functions that are difficult to plot and describe and involves parameters that are not easily related to the relevant underlying biophysical processes. (jneurosci.org)

This multidisciplinary approach will generate an integrated view of locomotion-plasticity that will not only impact basic cell biology and immunology but also developmental and cancer biology. (europa.eu)

Finally, we have basic theory projects relating to the experimental work just described, as well as in transport and structure in complex colloidal or zeolite systems, protein dynamics, and fundamental issues in quantum and statistical mechanics. (mcgill.ca)

Our team employs home developed softwares to model biophysical processes (NBS tools). (hun-ren.hu)

Inter- and transdisciplinary knowledge on biophysical cause-effect interrelations of human-environmental systems as well as their integratability in management and governance on the local and regional level are in the centre. (tu-dresden.de)
Achievement in tissues and/or cell cryopreservation is made upon the knowledge of biophysical basics root any cryobiological process (Fuller and Paynter, 2004). (iassist2012.org)
Basic knowledge of biology and mathematics recommended. (tum.de)
By studying the integration of knowledge from a number of the biophysical subdisciplines, students will be better prepared for advanced study and careers reliant on the integration of knowledge from various disciplines and perspectives. (humankinetics.com)
The aim of the course is to offer recently accepted graduate students at KILU an introduction to the workplace with respect to general employment conditions, key tools for documentation of own work, basic level knowledge of academic code of conduct regarding academic honesty and interpersonal relations. (lu.se)

The lab is particularly interested in better understanding how plant structure and function impacts biophysical processes across scales. (ucdavis.edu)

Living systems are full of interfaces and they have adopted to regulate adsorption/ desorption processes. (lu.se)

It is clear that colloid science has reached such a level that it can contribute with much larger consequences to the understanding of a range of processes in biological systems, than was possible during the fi rst half of the previous century. (lu.se)

We're a group of scientists and engineers based at the University of Arizona-home to the mission's Principal Investigator's office and the Science Processing Operations Center-ready to answer your questions about OSIRIS-REx, EGA, and the mission to collect some of the oldest material in the solar system. (authorea.com)

After taking part in this course, students are familiar with basic neuroanatomy and the neural processes in different sensory systems (visual, auditory). (tum.de)

If we continue to push against biophysical realities, we will eventually reach ecological collapse. (newfoodmagazine.com)

In our case, the DNA strands self-assemble into a flat rectangular structure, which serves as the basic building block for many DNA origami-based studies at the moment," says Maximilian Strauss, joint first author of the new paper, together with Florian Sch der and Daniel Haas. (nanotech-now.com)
As such, we provide services and make equipment available in the areas of recombinant protein production, crystallisation, biophysical characterization, and structure determination. (lu.se)
LP3 and PPS offer services for the entire process chain of production, purification, characterization, protein crystallisation and protein structure determination and structure refinement, or each individual step in the chain. (lu.se)

Our results show that the biophysical properties of aggregates determine both their mechanism of internalization and proteostatic response. (ugent.be)
Our results demonstrate that cortical neurons can be conceptualized as multi-layered "deep" processing units, implying that the cortical networks they form have a non-classical architecture and are potentially more computationally powerful than previously assumed. (biorxiv.org)

The Bailey Lab is working to develop the next generation of high-performance computational tools that enable improved analysis and prediction of plant biophysical processes. (ucdavis.edu)

We are particularly interested in plastic changes in the brain that compensate for some aspects of altered auditory input, and how those changes relate to central auditory processing deficits, tinnitus, and hyperacusis. (hopkinsmedicine.org)

Furthermore, few to no data can be found on the basic safety aspects natural to offspring era with gametes produced from frozen-thawed TT or TCSs. (iassist2012.org)
This allows users to have their crystals rapidly evaluated for diffraction and LP3 can also offer the possibility to process data and solve structures. (lu.se)
LP3 can further process data, solve and refine protein structures. (lu.se)

and computational modelling, image processing and analysis. (ubc.ca)
The fast response probe can be used for preliminary analysis of physiological processes with instantaneous (millisecond) potential changes, such as nerve impulses. (creative-bioarray.com)

With the recent development of sophisticated genetical, optical and electrical techniques it has become clear that many key neuron types (e.g., cortical and hippocampal pyramidal neurons, cerebellar Purkinje cells) are highly complicated I/O information processing devices. (biorxiv.org)
Daffodil International University is committed to develop efficient human resources to foster the national development process through an academic institution of higher education. (hmamedicalclinic.com)
However, development of a therapeutic antibody remains a complex process. (bvsalud.org)

Nevertheless, inter-center variability must end up being overcome as well as the gametes created for reproduction reasons have to be subjected to basic safety L-Theanine studies. (iassist2012.org)
Following a general introduction to the field of human movement studies, readers are introduced to basic concepts, life-span changes, and adaptations arising in response to training in each of the five major biophysical subdisciplines of human movement. (humankinetics.com)

Second question: do you then, Professor, see growth as a continuing process, desirable in itself, or as a temporary process required to reach a sufficient level of wealth that would thereafter be maintained more or less in a steady state? (archleague.org)

Using a model synapse, we relate the functions used in the fit to underlying biophysical processes. (jneurosci.org)

The Acoustics of Speech and Hearing is an H-Level graduate course that reviews the physical processes involved in the production, propagation and reception of human speech. (oercommons.org)
The third edition of Biophysical FFoundations of Human Movement offers a comprehensive introduction for students, scientists, and practitioners involved in the many professions grounded in or related to human movement, kinesiology, and sport and exercise science. (humankinetics.com)
The traditional process of discovering previously unknown human viruses, or variants of known viruses, is neither rapid nor thoroughly systematic. (cdc.gov)
Schematic representation of a process for systematic discovery of human viruses. (cdc.gov)
These samples would be pooled and processed by using available technology to isolate virus particles en masse, recover viral nucleic acids, produce amplified shotgun libraries, carry out shotgun sequencing of the mixture of viral genomes, and reconstruct these genomes in silico with the techniques originally developed to sequence the entire human genome from random fragments. (cdc.gov)

A central objective is to continually repeat this monitoring process to determine which agents change in abundance over time, find undiscovered agents already present, and detect new viruses when they appear. (cdc.gov)

She stressed the need for US agricultural systems to diversify beyond the major commodity crops, most of which are processed into animal feed. (newfoodmagazine.com)
Surprisingly, most of the systems and technology to carry out this process exist in a basic form and have been successfully employed to survey the extremely varied DNA virus population of the oceans. (cdc.gov)

Sustainalink is a matchmaker between students and companies, check out their web page sv /en and take the chance to contact them with your cv. (lu.se)

In fact, infection is a multi-factorial process that depends largely on how contaminated a wound is, how large and deep it is, which bacteria are present and factors such as age and co-morbidities of the patient. (bath.ac.uk)
The basic process (left vertical series of steps) depends on physical isolation and shotgun sequencing to obtain sequences of frequent. (cdc.gov)

Starting with the basics regarding biophysical and energy requirements of all growth-processes, Røpke was quick to weave in critiques on the purely money-focused, supply side based macromodels in general (and the Danish one in particular). (degrowth.info)

Biochemical and biophysical1

Chemistry6

Biophysics2

Principles3

Molecular6

Structural2

Synaptic2

Cellular6

Pathways3

Theoretical1

Foundations2

Research9

Approaches1

Mechanisms4

Proteins1

Energetic2

Regulation2

Methods3

Laboratory1

Researchers1

Clinical2

Interactions1

Investigates1

Models4

Parameters3

Cell biology1

Fundamental1

Employs1

Knowledge5

Function1

Interfaces1

Biological systems1

System1

Neural1

Ecological1

Structure3

Results2

Tools1

Auditory1

Data3

Analysis2

Development3

Studies2

Desirable1

Relate1

Human5

Determine1

Systems2

Students1

Depends2

General1