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  • proteome
  • The failure of any single method to identify all sites in highly phosphorylated Net1N, however, raises significant concerns about how feasible it is to map phosphorylation sites throughout the proteome using existing technologies. (mcponline.org)
  • Molecular
  • Further studies on acid-labile [ 32 P]phosphate bound to high-molecular weight material from rat-liver cell sap after incubation with [ 32 P]adenosine triphosphate. (springer.com)
  • inactive
  • Another ancillary protein, Cdh1, which keeps the APC/C active in G1, is converted by phosphorylation to an inactive form in the G1 to S-phase transition ( 3 , 4 ). (pnas.org)
  • The path to myosin filament formation, which is shared by NM II and smooth muscle myosin, starts with a folded inactive conformation of the NM II monomer which, upon phosphorylation of the 20 KDa light chain unfolds the molecule to produce a globular head region followed by an extended alpha-helical coiled-coil tail. (wikipedia.org)
  • interaction
  • APC/C is activated in mitosis in a process initiated by the phosphorylation of several of its subunits ( 5 , 6 ), which is necessary for its interaction with the activatory protein Cdc20 ( 7 , 8 ). (pnas.org)
  • Mutations of two protein trafficking motifs within the 38-amino acid region in CFTR each disrupted the interaction. (jci.org)
  • near
  • Most notably, the presence of a basic residue near the phosphorylated residue significantly hampered the ability of alkaline phosphatase to hydrolyze the phosphate moiety. (mcponline.org)