• The epidermis primarily consists of keratinocytes (proliferating basal and differentiated suprabasal), which comprise 90% of its cells, but also contains melanocytes, Langerhans cells, Merkel cells,: 2-3 and inflammatory cells. (wikipedia.org)
  • granular layer (stratum granulosum) Keratinocytes lose their nuclei and their cytoplasm appears granular. (wikipedia.org)
  • spinous layer (stratum spinosum) Keratinocytes become connected through desmosomes and produce lamellar bodies, from within the Golgi, enriched in polar lipids, glycosphingolipids, free sterols, phospholipids and catabolic enzymes. (wikipedia.org)
  • basal/germinal layer (stratum basale/germinativum) Composed mainly of proliferating and non-proliferating keratinocytes, attached to the basement membrane by hemidesmosomes. (wikipedia.org)
  • Instead, the inflamed CK-positive parts resembled epidermal keratinocytes grown in organotypic culture, which can be induced to build a noncornifying epithelium and to express CK19 with the addition of retinoic acid to the culture medium. (medscape.com)
  • The epidermis is a stratified squamous epithelium, composed of proliferating basal and differentiated suprabasal keratinocytes which acts as the body's major barrier against an inhospitable environment, by preventing pathogens from entering, making the skin a natural barrier to infection.It also regulates the amount of water released from the body into the atmosphere through transepidermal water loss. (emergencyphysio.com)
  • The top layer of the skin can be thought of as a brick wall, with the corneocytes (the keratinocytes that have migrated to the stratum corneum) being the bricks and the lipids being the cement. (9skincare.nl)
  • This entity was first identified and documented by Headington 9 in 1976, who described an epidermal-based tumor composed of atypical clear cells derived from adnexal keratinocytes. (jcadonline.com)
  • IL-6 was immunologically detected in basal keratinocytes, endothelial cells and in a number of mononucleated cells and fibroblasts in normal skin and sudoriparous ducts. (medicaljournals.se)
  • The cells in all of the layers except the stratum basale are called keratinocytes. (assignguru.com)
  • The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from the deeper layers. (assignguru.com)
  • A basal cell is a cuboidal-shaped stem cell that is a precursor of the keratinocytes of the epidermis. (assignguru.com)
  • All of the keratinocytes are produced from this single layer of cells, which are constantly going through mitosis to produce new cells. (assignguru.com)
  • Keratinocytes make up the majority of epidermal cells, comprising 95% of the epidermis. (keratinocyte-transfection.com)
  • Skin is a multilayered organ and keratinocytes form the protective outer layer. (wsu.edu)
  • The epithelial cells are called keratinocytes and they have different structures within the different layers of the epidermis (from the deeper basal layer, to spinous, granular to the corny layer at the surface). (eczemablues.com)
  • Dry skin is partly due to a disrupted barrier and trans epidermal water loss (TEWL). (9skincare.nl)
  • The ceramides in the skin (the cement) are responsible for retaining water and preventing trans epidermal water loss (TEWL). (9skincare.nl)
  • Also known as vitamin B3, it boosts skin immunity, increases the production of ceramides (an essential component of the skin's lipid barrier) and prevents trans epidermal water loss, regulating oil flow. (plastic-surgery-brisbane.com.au)
  • Costa cross-section semicircular bulging dorsally, with a single layer of guide cells and with a strong dorsal stereid band but with the ventral area composed primarily of substereidal cells, with well differentiated epidermal cells on both surfaces. (berkeley.edu)
  • Melanoma is a different form of cancer from BCC and SCC, as it doesn't stem from the skin's epidermal layers. (dandelife.com)
  • Stratum corneum, uppermost layer, is made up of corneocytes (flat, dead skin cells) forming skin's barrier. (skinceuticals.sg)
  • More than just smoothing and plumping, this moisturiser takes a medical approach to restoring optimal skin health, improving epidermal balance, boosting the skin's immunity, regulating oil flow, reducing oxidative stress and stimulating collagen production. (plastic-surgery-brisbane.com.au)
  • It molecules are small enough to penetrate the skin's epidermis to reach the dermis layer of the skin, where lines and wrinkles form. (plastic-surgery-brisbane.com.au)
  • When delivered correctly, hyaluronic acid enhances the skin's moisture content, plumping from below while making the skin's outer layer softer, more hydrated and radiant. (plastic-surgery-brisbane.com.au)
  • Basal cell carcinomas (BCCs) arise in the skin's basal cells, which line the deepest layer of the epidermis, and are usually caused by a combination of cumulative and intense, occasional sun exposure. (celebhealth.com)
  • Compared with the normal epidermis and type I epithelium, types II and III epithelia have Dsc2 and Dsg3 in all layers, whereas Dsc3 is restricted to the basal and parabasal layers. (medscape.com)
  • The strongly inflamed CK19-positive parts of the sinus epithelium show no signs of terminal squamous differentiation (ie, nuclei were present in the highest suprabasal layers, and keratohyalin granules were absent). (medscape.com)
  • In both normal pilosebaceous duct epithelium and cornifying type I sinus epithelium, CK5 and CK14 are restricted to the basal layer, CK10 and Dsc1 antibodies label the suprabasal cells, Dsg1 and Dsg3 are present in an epidermislike pattern, and CK2e is absent. (medscape.com)
  • Figure 5.4 Epidermis The epidermis is epithelium composed of multiple layers of cells. (assignguru.com)
  • The basal layer consists of cuboidal cells, whereas the outer layers are squamous, keratinized cells, so the whole epithelium is often described as being keratinized stratified squamous epithelium. (assignguru.com)
  • The skin is ectodermal in origin, and composed of a several differentiated layers of epithelium. (keratinocyte-transfection.com)
  • Each layer is made up of flat, scale-like squamous cells which typify superficial epithelium. (keratinocyte-transfection.com)
  • It consists of the cellular epithelium, that has an outer extracellular matrix - the cuticula - and an inner extracellular matrix - the basement membrane. (collembola.org)
  • In entomology the cell layer of the body wall is commonly called the "hypodermis", but the term epidermis is preferable inasmuch as the integumental epithelium is the homologue of the ectodermal layer of the skin so designated in vertebrate anatomy, though either term is illogical when applied to invertebrates having no accompanying "dermis" (Snodgrass, 1935). (collembola.org)
  • Fig.2) There were cystic invaginations from the surface, lined by stratified sqaumous epithelium transforming into a double layered epithelium. (ijcrr.com)
  • Fig.3) Outer layer of epithelium was lined by cuboidal cells and the inner layer by columnar cells, a few of which showed decapitation secretion. (ijcrr.com)
  • The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. (wikipedia.org)
  • The epidermis is composed of the outermost layers of cells in the skin,"epi" in Greek meaning "over" or "upon", which together with the dermis forms the cutis. (emergencyphysio.com)
  • Our skin is composed of three layers: the epidermis, the dermis and the subcutis. (9skincare.nl)
  • The outer layer, the epidermis (epidermis), is separated from the dermis by a thin basal membrane. (9skincare.nl)
  • Figure 5.2 Layers of Skin The skin is composed of two main layers: the epidermis, made of closely packed epithelial cells, and the dermis, made of dense, irregular connective tissue that houses blood vessels, hair follicles, sweat glands, and other structures. (assignguru.com)
  • The stratum basale (also called the stratum germinativum) is the deepest epidermal layer and attaches the epidermis to the basal lamina, below which lie the layers of the dermis. (assignguru.com)
  • The outermost layer of the face is the skin, which comprises of the epidermis and the dermis. (beautytrainingportal.com)
  • This skin renewal is not related to wrinkles as wrinkles are primarily due to the loss of collagen , which is in the dermis (middle layer) of skin. (eczemablues.com)
  • The skin is composed of several layers (hypodermis, dermis, epidermis) and tegumentary appendages (hair, sebaceous gland). (cherrybiotech.com)
  • The three layers of the skin (hypodermis, dermis, and epidermis) are reconstituted by three supports of PDMS on which the cells are cultured. (cherrybiotech.com)
  • Skin gets its protective properties from its three-layer defense system: the epidermis (the outermost layer), the dermis and, below both, a fatty layer. (celebhealth.com)
  • Basal/germinal layer (stratum basale/germinativum). (emergencyphysio.com)
  • As I will lay out nekkid skin perhaps highly keratinized or fleshy - the most basal, germinal layer of all - on the head and even neck in many cases is a quite defensible option for theropods and perhaps even other dinosaurs. (blogspot.com)
  • The epidermis is composed of multiple layers of flattened cells that overlie a base layer (stratum basale) composed of columnar cells arranged perpendicularly. (wikipedia.org)
  • The layers of cells develop from stem cells in the basal layer. (wikipedia.org)
  • Epidermal cells are tightly interconnected to serve as a tight barrier against the exterior environment. (wikipedia.org)
  • The junctions between the epidermal cells are of the adherens junction type, formed by transmembrane proteins called cadherins. (wikipedia.org)
  • Langerhans cells, immunologically active cells, are located in the middle of this layer. (wikipedia.org)
  • Differentiating cells delaminate from the basement membrane and are displaced outward through the epidermal layers, undergoing multiple stages of differentiation until, in the stratum corneum, losing their nucleus and fusing to squamous sheets, which are eventually shed from the surface (desquamation). (wikipedia.org)
  • CK19 is commonly found in the basal cells of noncornifying stratified squamous epithelia, such as in the outer root sheath (ORS) of the hair follicle. (medscape.com)
  • Differentiated elongate basal cells markedly few in number, often present only near costa at extreme leaf base, arranged in regular rows, moderately thick-walled with the lumen/wall ratio about 2-4: 1, to 10 µm broad, 2-4: 1, with straight and not pitted lateral walls. (berkeley.edu)
  • Stem rounded pentagonal in cross-section, with central strand, and with thin-walled inner cortical cells grading to 1-3 layers of thicker walled, smaller outer cortical cells. (berkeley.edu)
  • The outer layer of skin, the epidermis, is made up of different types of cells. (findmeacure.com)
  • Basal cell carcinoma develops from abnormal growth of the cells in the lowest layer of the epidermis and is the most common type of skin cancer. (findmeacure.com)
  • Squamous cell carcinoma involves changes in the squamous cells, found in the middle layer of the epidermis. (findmeacure.com)
  • Melanoma occurs in the melanocytes (cells that produce pigment) and is less common than squamous or basal cell carcinoma, but more dangerous. (findmeacure.com)
  • BCC refers to abnormal lesions that arise in the basal cells that are found deep in the epidermal layer of the skin.Squamous cell carcinoma is another type of skin cancer. (goodlifechronicle.com)
  • It develops in the squamous cells that are on the outer part of the epidermis. (goodlifechronicle.com)
  • During the procedure, thin layers of skin tissue are removed and examined under a microscope,and this will show up any cancer cells present. (goodlifechronicle.com)
  • Another method that surgeons prefer is Mohs Surgery, in which the surgeon removes the mole and the affected skin along with the nearby tissues and skin layers to be more assured that the contamination of cancer cells won't spread. (dandelife.com)
  • The antheridial cavities are completely covered by a double layer of cells . (istudy.pk)
  • A space is produced between inner and outer cells. (istudy.pk)
  • 5. The jacket cells by further divisions produce a single layered wall. (istudy.pk)
  • Thus, it is important to understand the different skin layers and cells found in the skin. (9skincare.nl)
  • It is a single-layered and it is made up of columnar cells. (rbsesolutions.com)
  • Some of the epidermal cells modify to form sensory cells. (rbsesolutions.com)
  • In addition, the epidermis also has few basal cells which are small and round /cone-shaped. (rbsesolutions.com)
  • Basal cells produce new skin cells when the old ones die. (healthwire.pk)
  • Squamous cells make up the middle and outer layers of the skin. (healthwire.pk)
  • The hair matrix is the actively growing portion of the follicle consisting of a collection of epidermal cells that rapidly divide, move upward, and give rise to the hair shaft and the internal root sheath. (medscape.com)
  • Melanocytes can be found between the basal cells of the hair matrix. (medscape.com)
  • The hair matrix cells give rise to 6 different types of cells that make up the different layers of the hair shaft and the inner root sheath. (medscape.com)
  • The cells of the innermost layer (IRS cuticle) point downward and inward and interconnect with the cells of the hair cuticle. (medscape.com)
  • The skin is made of multiple layers of cells and tissues, which are held to underlying structures by connective tissue. (assignguru.com)
  • It is made of four or five layers of epithelial cells, depending on its location in the body. (assignguru.com)
  • Skin that has four layers of cells is referred to as "thin skin. (assignguru.com)
  • The stratum basale is a single layer of cells primarily made of basal cells. (assignguru.com)
  • Two other cell types are found dispersed among the basal cells in the stratum basale. (assignguru.com)
  • In a growing fetus, fingerprints form where the cells of the stratum basale meet the papillae of the underlying dermal layer (papillary layer), resulting in the formation of the ridges on your fingers that you recognize as fingerprints. (assignguru.com)
  • The epidermis is the skin, or, more specifically, the outer layer of mammalian skin cells. (keratinocyte-transfection.com)
  • This layer creates cells, which then differentiate and migrate towards the more superficial layers of the skin. (keratinocyte-transfection.com)
  • Further down lie the basal cells, some of which "button" the skin to underlying connective tissue by tiny structures called spot wells. (wsu.edu)
  • This process of shedding and renewing of epidermal cells is called desquamation. (beautytrainingportal.com)
  • The cells in this layer are dry and at. (beautytrainingportal.com)
  • This layer may have between 18-23 layers of at dry cells that are cemented together by lipids, peptides, sebum and ceramides. (beautytrainingportal.com)
  • In this layer the lipids separate from the keratin (a non-living substance), ands cells lose a considerable amount of fat and moisture. (beautytrainingportal.com)
  • This layer is called the spiny cell layer due to the spiky appearance of the cells. (beautytrainingportal.com)
  • The dermatological terms are ' epidermal cell proliferation ' which takes into account the turnover of cells and there are differences between normal adult, baby and eczema skin. (eczemablues.com)
  • The skin regenerate itself every 27 to 39 days, meaning that the cells from the lower layer of the epidermis (outer layer) move up to the surface and differentiate. (eczemablues.com)
  • In people with eczema, there is lower level of FLG, resulting in flatter skin surface cells, disrupted protective fatty layer, reducing the moisturizing function of the skin and increasing water loss from the skin. (eczemablues.com)
  • Receptor cell type 1 (two cells in cone-shaped sensilla, one cell in peg-shaped sensilla) possesses two long dendritic outer segments that project to the terminal pore. (biomedcentral.com)
  • The nearly identical configuration of receptor cells 1 with their long dendritic outer segments in both sensilla is similar to hexapod hygroreceptors. (biomedcentral.com)
  • It consists of a single layer of polyhedral cells. (collembola.org)
  • The pattern of these surface characters appears in some cases to have a relation to that of the underlying epidermal cells, but in others it seems to be entirely unrelated to the cell arrangement. (collembola.org)
  • Cuticular structures of this nature are hollow outgrowths of the entire body wall and are therefore lined by a layer of formative epidermal cells. (collembola.org)
  • These conserved families of secreted morphogens/signals, such as Fibroblast Growth Factor (FGF), Hedgehog (Hh), Wingless (Wg)/Wnt, Epidermal Growth Factor (EGF), and Decapentaplegic (Dpp - a BMP homolog), act away from their sources and, upon binding to receptors, activate gene regulatory pathways to induce functions in recipient cells 1 , 2 . (biorxiv.org)
  • If you zoom on the cells at the outermost layer of this section of skin, what do you notice about the cells? (edu.vn)
  • It is many-layer in thickness and composed of large parenchymatous cells. (biologylearner.com)
  • As the stem matures, the outer cells of the cortex become thick-walled and are reddish-brown in colour. (biologylearner.com)
  • The leaf lamina is made up of a single layer of parenchymatous polygonal cells. (biologylearner.com)
  • This book is about the phenotypic and functional features of epidermal Langerhans cells in experimental models and in clinical medicine. (netlify.app)
  • Langerhans cells (LC) are members of the dendritic cells family, residing in the basal and suprabasal layers of the epidermis and in the epithelia of the respiratory, digestive and urogenital tracts. (netlify.app)
  • Found largely in the epidermis, the outer layer of the skin, as well as in lymph nodes, Langerhans cells are an important element of the immune system. (netlify.app)
  • Langerhans cell histiocytosis (LCH) and In LCH, overproduced, immature Langerhans cells cluster together and Cytokine pattern of Langerhans cells isolated from murine epidermal cell cultures. (netlify.app)
  • The uppermost layer thickens, causing cells to stick together and clog pores. (skinceuticals.sg)
  • The cells are grown in 3D and have shown the ability to recreate the different layers of the skin (comparable to the human skin). (cherrybiotech.com)
  • Melanin is a pigment produced by cells in the epidermal layer. (celebhealth.com)
  • Ceruminoma (cancer of the cells that produce earwax) develops in the outer third of the ear canal. (msdmanuals.com)
  • Corneocytes contain a protein envelope (cornified envelope proteins) underneath the plasma membrane, are filled with water-retaining keratin proteins, attached together through corneodesmosomes and surrounded in the extracellular space by stacked layers of lipids. (wikipedia.org)
  • Peristome yellow- to reddish-brown, to 2 mm long, divided to base, without basal membrane, with the segments papillose-spiculose throughout, straight to several times spirally twisted. (berkeley.edu)
  • GAGs bound into PGs are located to the extracellular matrix, basal membrane, and cell surface [ 7 ]. (hindawi.com)
  • Each layer is separated by a porous membrane (PET, 0.4 μM pore). (cherrybiotech.com)
  • Advantages: the vascularization strengthens the basal lamina and allows the study of the interactions between the vascular compartment and the extracellular matrix. (cherrybiotech.com)
  • Trichilemmal carcinoma (TC) is a rare cutaneous tumor thought to be derived from the follicular outer root sheath (ORS). (jcadonline.com)
  • Trichilemmal carcinomas (TCs) are rare, malignant, adnexal neoplasms that differentiate from the outer root sheath (ORS) of the hair follicle. (jcadonline.com)
  • Pronounced nuclear staining was limited to the area below the critical line of Auber and the exterior part of the outer root sheath. (medicaljournals.se)
  • Many laymen and even professionals consider the basal cell carcinoma (BCC), the squamous cell carcinoma (SCC) and the malignant melanoma as one group - namely skin cancer. (findmeacure.com)
  • While moisturising and smoothing the skin, tentative research also shows that is may reduce the risk of non melanoma skin cancers among people who have previously had basal cell carcinoma or squamous cell carcinoma. (plastic-surgery-brisbane.com.au)
  • The majority of these are called Basal Cell Carcinomas . (findmeacure.com)
  • The three types of skin cancers (in order of the danger they pose to people of color) are malignant melanomas, squamous cell carcinomas and basal cell carcinomas. (celebhealth.com)
  • clear/translucent layer (stratum lucidum, only in palms and soles) This narrow layer is found only on the palms and soles. (wikipedia.org)
  • From bottom to top, these are: the stratum basal, stratum spinosum, stratum granulosum, stratum lucidum and the stratum corneum (the stratum corneum). (9skincare.nl)
  • It has a fifth layer, called the stratum lucidum, located between the stratum corneum and the stratum granulosum. (assignguru.com)
  • Figure 5.5 Layers of the Epidermis The epidermis of thick skin has five layers: stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum. (assignguru.com)
  • The main differentiating histological feature in a TC is the evidence of trichilemmal keratinization, where the tumor exhibits an absence of granular layer between the stratum spinosum and stratum corneum. (jcadonline.com)
  • Epidermal thickenings called Rete ridges (or rete pegs) extend downward between dermal papillae. (wikipedia.org)
  • The leaves of the monocot plants have a thick layering of cuticle on the upper epidermal surface. (biodifferences.com)
  • The middle layer (Huxley layer) keratinizes after the IRS cuticle and the hair cuticle. (medscape.com)
  • Beneath this is the subcutaneous layer, where the superficial fat pads are found. (beautytrainingportal.com)
  • It will also benefit patients with defects or damages to the upper layers of their skin including conditions such as superficial skin growths, small cysts, Bowen's disease (basal cell skin cancer) or epidermal nevi. (lgbti.org)
  • Several solitary recto-canal epidermal glands produce the secretion. (biomedcentral.com)
  • Corneocytes are surrounded by a protein envelope (cornified envelope proteins), filled with water-retaining keratin proteins, attached together through corneodesmosomes and surrounded in the extracellular space by stacked layers of lipids. (emergencyphysio.com)
  • In addition, inflammation of the mutant skin is evident, although not causative of the epidermal defects. (biologists.com)
  • Mice lacking the epidermal growth factor receptor (EGFR) develop epithelial defects and a neurodegenerative disease and die within the first month of birth. (silverchair.com)
  • The epidermis of these two areas is known as "thick skin" because with this extra layer, the skin has 5 epidermal layers instead of 4. (wikipedia.org)
  • Note the significant difference in the thickness of the epithelial layer of the thick skin. (assignguru.com)
  • Subcutaneous layer - a thick layer composed of fatty connective tissue that varies in thickness in each person. (beautytrainingportal.com)
  • The large basal ganglia subsequently differentiate from the striatal part of the cerebral vesicle. (ehd.org)
  • The epidermis layer provides a barrier to infection from environmental pathogens and regulates the amount of water released from the body into the atmosphere through transepidermal water loss. (wikipedia.org)
  • Most of the barrier functions of the epidermis localize to this layer. (wikipedia.org)
  • Outer layer of skin that acts as a barrier between the body and the environment. (skinceuticals.sg)
  • With a healthier epidermal lipid barrier, the skin is more resistant to environmental damage. (plastic-surgery-brisbane.com.au)
  • Langerhans Cell-Histiocytos Langerhans Cell-Histiocytos (LCH) är en ovanlig och gåtfull sjukdom som i huvudsak drabbar barn och som tidigare varit mest känd under beteckningen Histiocytosis X. Förekomst Enligt vad vi vet idag drabbas 5-10 barn i Sverige av sjukdomen varje år. (netlify.app)
  • 3 While the clinical differential diagnosis commonly includes basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and keratoacanthoma, the histopathological differential also includes trichilemmoma, trichoepithelioma, clear cell SCC, clear cell porocarcinoma, and clear cell hidradenocarcinoma. (jcadonline.com)
  • The most common benign and malignant neoplasms arising in this disorder include trichilemmoma, syringocystadenoma papilliferum, keratoacanthoma, apocrine cystadenoma and basal cell carcinoma. (ijcrr.com)
  • The deeper layer of skin is well vascularized (has numerous blood vessels). (assignguru.com)
  • We now understand that this deeper layer comprises of multiple discrete fat compartments (referred to as the deep fat pads) and facial muscles. (beautytrainingportal.com)
  • The outer cell divides to form roof of antheridial cavity . (istudy.pk)
  • Those layers from outermost to innermost are: cornified layer (stratum corneum) Composed of 10 to 30 layers of polyhedral, anucleated corneocytes (final step of keratinocyte differentiation), with the palms and soles having the most layers. (wikipedia.org)
  • Composed of 10 to 30 layers of polyhedral, anucleated corneocytes (final step of keratinocyte differentiation), with the palms and soles having the most layers. (emergencyphysio.com)
  • Keratinocyte differentiation throughout the epidermis is in part mediated by a calcium gradient, increasing from the stratum basale until the outer stratum granulosum, where it reaches its maximum, and decreasing in the stratum corneum. (emergencyphysio.com)
  • This calcium gradient parallels keratinocyte differentiation and as such is considered a key regulator in the formation of the epidermal layers. (emergencyphysio.com)
  • Receptor cell type 2 (one cell in both sensilla) possesses two shorter dendritic outer segments connected to the first (proximal) sheath cell that establishes a scolopale-like structure, documented for the first time in detail in a myriapod sensillum. (biomedcentral.com)
  • Water vapor may lead to swelling and subsequent elongation of the plug pin that enters the terminal pore, thus causing stimulation of the elongated dendritic outer segments. (biomedcentral.com)
  • The interconnection of receptor cell 2 with short outer dendritic segments to a scolopale-like structure potentially suits both sensilla for vibration or strain detection. (biomedcentral.com)
  • is based on an epidermal by exocytosis regulated receptor mediated deposition of lipocuticulin micellae. (collembola.org)
  • Thus, GAGs/PGs may modulate downstream signaling of key cellular mediators including insulin growth factor receptor (IGFR), epidermal growth factor receptor (EGFR), estrogen receptors (ERs), or Wnt members. (hindawi.com)
  • The noncornifying types II and III epithelia are characterized by the absence of the terminal differentiation markers CK10 and Dsc1 and by the strong expression of Dsg2 in the basal layer. (medscape.com)
  • It occurs on the epidermal (outer layer) and is very similar to basal cell carcinoma in many ways. (trustedhealthproducts.com)
  • Its health and surface appearance are determined by environmental factors as well as the function of the components that comprise the layers below. (skinceuticals.sg)
  • The uppermost layer is thin and jagged due to lack of water in certain areas of the face. (skinceuticals.sg)