• In addition, it is worth noting that the ligand-binding pocket of many receptors is located inside the cell membrane, due to which lipids can even modulate the binding of ligands to their receptors. (bvsalud.org)
  • The detection of harmful stimuli such as noxious chemicals and changes in temperature and pressure are fundamental biological processes carried out by numerous cell types through diverse specialized receptors. (elifesciences.org)
  • Notable human health toxicity effects identified from human and/or animal studies include respiratory cancer, non-cancer toxicity effects following inhalation, dermatitis, and reproductive effects. (mdpi.com)
  • The aim of this study was to determine if the inhibition of GJIC by PFOA but not perfluoropentanoate (PFPeA) observed in F344 rat liver cells in vitro also occurs in F344 rats in vivo and to determine mechanisms of PFOA dysregulation of GJIC using in vitro assay systems. (nih.gov)
  • Chronic exposure of rats resulted in increased thyroid follicular cell tumors from sustained perturbation of thyroid hormone homeostasis. (cdc.gov)
  • Al Ain, Ras Al Khaimah, and Fujairah have trying in some cells but get boldly before Keeping actually - they advance not the vulnerable as Dubai or Abu Dhabi. (freelanceadcopy.com)