• Geodon (ziprasidone HCl and ziprasidone mesylate) is an atypical antipsychotic used to treat symptoms of schizophrenia and acute manic or mixed episodes associated with bipolar disorder . (rxlist.com)
  • Back and forth, up and down you go … you cannot get relief …" Medication-induced akathisia is termed acute akathisia and is frequently associated with the use of antipsychotics. (wikipedia.org)
  • The acute movement disorders that occur as manifestations of effects of neuroleptics and other dopamine antagonists include akathisia, acute dystonia, and other hyperkinetic dyskinesias. (medscape.com)
  • Antipsychotics block dopamine receptors, but the pathophysiology is poorly understood. (wikipedia.org)
  • Since dopamine deficiency (or disruptions in dopamine signalling) appears to play an important role in the development of Restless Legs Syndrome (RLS), a form of akathisia focused in the legs,[medical citation needed] the sudden withdrawal or rapidly decreased dosage of drugs which increase dopamine signalling may create similar deficits of the chemical which mimic dopamine antagonism and thus can precipitate RLS. (wikipedia.org)
  • Antipsychotic medication, particularly the first generation antipsychotics, are a leading cause. (wikipedia.org)
  • Akathisia is usually grouped as a medication-induced movement disorder but is also seen to be a neuropsychiatric concern as it can be experienced purely subjectively with no apparent movement abnormalities. (wikipedia.org)
  • When due to psychiatric drugs, the symptoms are side effects that usually disappear quickly and remarkably when the medication is reduced or stopped. (wikipedia.org)
  • However, tardive akathisia which has a late onset, may go on long after the medication is discontinued, for months and sometimes years. (wikipedia.org)
  • Additionally, drugs with successful therapeutic effects in the treatment of medication-induced akathisia have provided additional insight into the involvement of other transmitter systems. (wikipedia.org)
  • TDs are most common in patients with schizophrenia, schizoaffective disorder, or bipolar disorder who have been treated with antipsychotic medication for long periods, but they occasionally occur in other patients as well. (medscape.com)
  • Taking antipsychotic medication such as Geodon during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms , breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. (rxlist.com)
  • Our Geodon Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • However, despite a lack of historical association between restless leg syndrome and akathisia, this does not guarantee that the two conditions do not share symptoms in individual cases. (wikipedia.org)
  • Symptoms of akathisia are often described in vague terms such as feeling nervous, uneasy, tense, twitchy, restless, and an inability to relax. (wikipedia.org)
  • When misdiagnosis occurs in antipsychotic-induced akathisia, more antipsychotic may be prescribed, potentially worsening the symptoms. (wikipedia.org)
  • If symptoms are not recognised and identified akathisia can increase in severity and lead to suicidal thoughts, aggression and violence. (wikipedia.org)
  • Treatment may include switching to an antipsychotic with a lower risk of the condition, if the akathisia was caused by an antipsychotic. (wikipedia.org)
  • Visible signs of akathisia include repetitive movements such as crossing and uncrossing the legs, and constant shifting from one foot to the other. (wikipedia.org)
  • Akathisia is also associated with threatening behaviour and physical aggression that is greatest in patients with mild akathisia, and diminishing with increasing severity of akathisia. (wikipedia.org)
  • Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. (rxlist.com)
  • The term was first used by Czech neuropsychiatrist Ladislav Haškovec, who described the phenomenon in 1901 long before the discovery of antipsychotics, with drug-induced akathisia first being described in 1960. (wikipedia.org)
  • Significant differences between the two groups were noted on the Barnes Rating Scale for Drug-Induced Akathisia and the Simpson-Angus Rating Scale for Drug-Induced Extrapyramidal Symptoms. (medscape.com)
  • Examples include recommendation of a slower taper and dosage-adjustment period when switching among antipsychotic agents, slower dosage adjustment of risperidone in patients susceptible to orthostatic hypotension or akathisia, and discontinuation of most selective serotonin-reuptake inhibitors over several days rather than abrupt discontinuation. (medscape.com)
  • Patients with a history of a clinically significant low white blood cell count (WBC) or a drug-induced leukopenia/neutropenia should have their complete blood count (CBC) monitored frequently during the first few months of therapy and discontinuation of INVEGA ® should be considered at the first sign of a clinically significant decline in WBC in the absence of other causative factors. (nih.gov)
  • This study aimed to investigate a possible association between the occurrence rates of HMB and different treatment methods such as antidepressant agents alone and in combination with other pharmacological agents. (bvsalud.org)
  • Ziprasidone is a psychotropic agent that is chemically unrelated to phenothiazine or butyrophenone antipsychotic agents. (rxlist.com)
  • Severe Cutaneous Adverse Reactions, su ch as Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) and Stevens-Johnson syndrome has been reported with ziprasidone exposure. (nih.gov)
  • Potentially fatal symptom complex has been reported with antipsychotic drugs. (nih.gov)
  • Treatment may include switching to an antipsychotic with a lower risk of the condition, if the akathisia was caused by an antipsychotic. (wikipedia.org)
  • Frmd8 deficiency in mice accelerates azoxymethane/dextran-sodium-sulfate-induced colorectal adenoma formation. (bvsalud.org)
  • Positive effects were observed with rating scales for drug-induced adverse events as well. (medscape.com)
  • The primary and secondary efficacy parameters were change from baseline to Week 3 in Young Mania Rating Scale (YMRS) and Clinical Global Impressions-Severity (CGI-S) scores, respectively. (nih.gov)