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Bacteroides fragilisBacteroidesBacteroides InfectionsBacteria, AnaerobicPrevotella melaninogenicaFusobacteriumClindamycinCefoxitinMicrobial Sensitivity TestsAbscessAnaerobiosisMetronidazoleDrug Resistance, MicrobialAnti-Bacterial AgentsImipenemCefotetanPrevotellaPeptostreptococcusBacteriaBacteria, AerobicAbdominal AbscessNaphthyridinesbeta-LactamasesDNA, BacterialGram-Negative Anaerobic BacteriaFecesSuppurationCephamycinsMoxalactamCephalosporinaseThienamycinsPorphyromonasFluoroquinolonesConjugation, GeneticAnti-Infective AgentsPolysaccharides, BacterialCephalosporinsPenicillanic AcidBacterial InfectionsCeftizoximeBacteroidaceaeGenes, BacterialTetracyclineClostridiumLactamsEscherichia coliBacterial ProteinsGram-Positive Bacteriabeta-LactamsCulture MediaDNA Transposable ElementsAza CompoundsCefmetazoleCedrusEnterotoxinsMetalloendopeptidasesPiperacillinSpecies SpecificityErythromycinMolecular Sequence DataSulbactamClavulanic AcidsPeptococcusFusobacterium InfectionsClavulanic AcidCefotaximeTicarcillinLincomycinColony Count, Microbial
BacteriaSpeciesPrevotellaGenusStreptococcusEnterotoxigenicESCHERICHIA COLICommensalBacteriumMelaninogenicaInfectionsStaphylococcusCefoxitinOrganismIntestinalToxinETBFAnaerobesFecalThetaiotaomicronAntibioticsMicrobiotaAerotolerantSpecimensImmunomodulatoryGenesOrganismsProteinsGroupInfectionAbnormalitiesSurviveCellsSignificantlyImportantHuman gutExpressionRoleAnalysisMedical
Bacteria7
  • Member of the genus Bacteroides are characterized with having the highest numbers of antibiotic resistance mechanisms accompanied by the highest resistance rates amongst anaerobic bacteria. (wikipedia.org)
  • This allows the genetic transfer of these genes to other Bacteroides species and possibly other more virulent bacteria leading to an overall increase in multi-drug resistance. (wikipedia.org)
  • citation needed] Although the B. fragilis group is the most common species found in clinical specimens, it is the least common Bacteroides present in fecal microbiota, comprising only 0.5% of the bacteria present in stool. (wikipedia.org)
  • B. fragilis is an aerotolerant anaerobic bacteria, which allows it to survive in environments with low levels of oxygen. (microchemlab.com)
  • Infections with bacteria of the genus BACTEROIDES . (lookformedical.com)
  • A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. (lookformedical.com)
  • in particular, the bacteria Bacteroides fragilis and Alistipes finegoldii have been found to cause CRC in mouse models, explained Gacesa. (medscape.com)
Species6
  • Resistance Reservoirs: Bacteroides species accumulate a variety of antibiotic/antimicrobial resistance genes as they reside in the gastrointestinal tract. (wikipedia.org)
  • Organisms of this genus had originally been classified as members of the BACTEROIDES genus but overwhelming biochemical and chemical findings in 1990 indicated the need to separate them from other Bacteroides species, and hence, this new genus was established. (lookformedical.com)
  • Of all species, B. fragilis causes most human Bacteroides infections. (unboundmedicine.com)
  • Other commonly encountered members of the B. fragilis group [BFG] include Bacteroides, Parabacteroides and Phocaeicola species: speciation has been aided by the employment of MALDI-TOF [3] . (unboundmedicine.com)
  • Resistance to β-lactam antibiotics in Bacteroides species. (microbiologyresearch.org)
  • Cultures revealed gram-negative Pseudomonas species and Bacteroides fragilis. (medscape.com)
Prevotella1
Genus4
  • Bacteroides fragilis is a member of the genus Bacteroides. (sound-pharmacy.com)
  • Inactivity and hypoxia resulted in a significant increase in the genus Bacteroides in HBR, in genes coding for proteins involved in iron acquisition and metabolism, cell wall, capsule, virulence, defense and mucin degradation, such as beta-galactosidase (EC3.2.1.23), α-L-fucosidase (EC3.2.1.51), Sialidase (EC3.2.1.18), and α-N-acetylglucosaminidase (EC3.2.1.50). (frontiersin.org)
  • The fact that the genus Bacteroides and proteins involved in iron acquisition and metabolism, cell wall, capsule, virulence and mucin degradation were enriched at the end of HBR suggest that both constipation and EC decreased intestinal metal availability leading to modified expression of co-regulated genes in Bacteroides genomes. (frontiersin.org)
  • In particular, diminished fecal abundance of Faecalibacterium prausnitzii and abnormalities in both directions in the abundance of the Bacteroides genus have been identified. (medscape.com)
Streptococcus1
  • Those microorganisms that are potential indicators of contamination in a dental environment include Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, Streptococcus mitis, Streptococcus salivarius, Corynebacterium diphtheriae, Bacteroides fragilis and Peptoestreptococus. (bvsalud.org)
Enterotoxigenic2
  • Enterotoxigenic Bacteroides fragilis (ETBF) causes diarrhea and is implicated in inflammatory bowel diseases and colorectal cancer. (elsevierpure.com)
  • Enterotoxigenic Bacteroides fragilis (ETBF) is a Gram-negative, obligate anaerobe member of the gut microbial community in up to 40% of healthy individuals. (bvsalud.org)
ESCHERICHIA COLI1
Commensal1
  • The gut commensal Bacteroides fragilis or its capsular polysaccharide A (PSA) can prevent various peripheral and CNS sterile inflammatory disorders. (nature.com)
Bacterium6
  • Bacteroides fragilis is an anaerobic, Gram-negative, pleomorphic to rod-shaped bacterium. (wikipedia.org)
  • Cells of B. fragilis are rod-shaped to pleomorphic with a cell size range of 0.5-1.5 x 1.0-6.0 μm.B. fragilis is a Gram-negative bacterium and does not possess flagella or cilia making it immotile. (wikipedia.org)
  • A Bacteroides fragilis gene (argF'(bf)), the disruption of which renders the bacterium auxotrophic for arginine, was expressed and its recombinant protein purified and studied. (nih.gov)
  • Bacteroides fragilis is an anaerobic bacterium naturally hosted in the human colon flora. (chemaxon.com)
  • Bacteroides fragilis is a Gram-negative, rod-shaped, non-motile bacterium found in the human colon. (microchemlab.com)
  • This is a scientifically proven instance where the bacterium Bacteroides fragilis prevents multiple sclerosis in mice. (kiyalongevity.com)
Melaninogenica1
  • Bacteroides melaninogenicus was later changed to Prevotela melaninogenica. (globalrph.com)
Infections4
  • The B. fragilis group is the most commonly isolated Bacteroidaceae in anaerobic infections, especially those that originate from the gastrointestinal microbiota. (wikipedia.org)
  • Bacteroides fragilis is involved in 90% of anaerobic peritoneal infections. (wikipedia.org)
  • Serological diagnosis of Bacteroides fragilis infections by a complement fixation test. (bmj.com)
  • B. fragilis is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality. (microchemlab.com)
Staphylococcus1
Cefoxitin1
Organism1
  • B. fragilis is the most prevalent organism in the B. fragilis group, accounting for 41% to 78% of the isolates of the group. (wikipedia.org)
Intestinal2
  • B. fragilis also utilizes a complex series of surface proteins, lipopolysaccharide chains, and outer membrane vesicles to help survive the volatile intestinal micro-environment. (wikipedia.org)
  • This system is composed of/designed to effectively handle: Bacteriocins: B. fragilis intestinal isolates secrete high levels of bacteriocin proteins and are resistant to other bacteriocins secreted by other closely related isolates. (wikipedia.org)
Toxin3
  • The only known ETBF virulence factor is the Bacteroides fragilis toxin (BFT), which induces E-cadherin cleavage, interleukin-8 secretion, and epithelial cell proliferation. (elsevierpure.com)
  • Epigenetic Changes Induced by Bacteroides fragilis Toxin. (bvsalud.org)
  • tumor formation is dependent on ETBF-secreted Bacteroides fragilis toxin (BFT). (bvsalud.org)
ETBF1
  • Specific pathogen-free (SPF) C57BL/6J or germfree 129S6/SvEv mice were orally inoculated with wild-type ETBF (WT-ETBF) strains, a nontoxigenic WT strain of B. fragilis (WT-NTBF), WT-NTBF overexpressing bft (rETBF), or WT-NTBF overexpressing a biologically inactive mutated bft (rNTBF). (elsevierpure.com)
Anaerobes1
  • Cytochrome bd oxidase is essential for oxygen consumption in B. fragilis and can allow other obligate anaerobes to survive in the now oxygen-reduced microenvironment. (wikipedia.org)
Fecal1
  • In contrast, the fecal abundance of Bacteroides fragilis was increased in ERA subjects (2.0 ± 4.0% versus 0.45 ± 0.7% of all sequences, p = 0.045), yet was diminished in adult subjects (0.2 ± % versus 1.0 ± % of all sequences, p = 0.106). (medscape.com)
Thetaiotaomicron1
Antibiotics3
  • The high resistance to antibiotics of B.fragilis is mainly attributed to genetic plasticity. (wikipedia.org)
  • Susceptibilities to β-lactam antibiotics and β-lactamase content of two groups of Bacteroides strains were compared. (microbiologyresearch.org)
  • Characterisation of a β-lactamase obtained from a strain of Bacteroides fragilis resistant to β-lactam antibiotics. (microbiologyresearch.org)
Microbiota1
  • B. fragilis and its OMVs have pivotal role in the cross talk between gut microbiota and the host especially in the modulation of the immune system. (celljournal.org)
Aerotolerant1
  • B. fragilis is an aerotolerant, anaerobic chemoorganotroph capable of fermenting a wide variety of glycans available in the human gut microenvironment including glucose, sucrose, & fructose. (wikipedia.org)
Specimens1
  • Paired specimens of serum from patients from whom Bacteroides fragilis had been isolated were tested by complement fixation against a crude B. fragilis antigen. (bmj.com)
Immunomodulatory1
  • Based on the last studies on immunomodulatory effect of B. fragilis derived OMVs on immune cells and our results, we postulate that B. fragilis derived OMVs could be possible candidates for the reduction of immune responses. (celljournal.org)
Genes1
  • In this study, we evaluated TLR2, TLR4 genes expression and cytokines concentration in Caco-2 cell line treated with Bacteroides fragilis (B. fragilis) and its OMVs. (celljournal.org)
Organisms1
  • The data provided herein suggest that B. fragilis uses N-succinyl-L-ornithine rather than N-acetyl-L-ornithine for de novo arginine biosynthesis and therefore that this pathway in Bacteroides is different from the canonical arginine biosynthetic pathway of most organisms. (nih.gov)
Proteins1
  • Maintaining a generally beneficial relationship with the host when retained in the gut, B. fragilis has adapted complex surface proteins and other molecular structures, such as lipopolysaccharide chains and outer membrane vesicles, in order to survive and thrive within the human gut environment. (microchemlab.com)
Group1
  • This group was formerly classified as subspecies of B. fragilis (i.e. (wikipedia.org)
Infection1
  • A high titre or a rise in titre to B. fragilis was obtained in each of five patients with infection after abdominal surgery but in none of 11 patients with postpartum pyrexia nor in nine with vaginitis. (bmj.com)
Abnormalities1
  • Treated with Bacteroides fragilis , these rodents were able to overcome their core abnormalities, including communication deficit, which is the diagnostic symptom of autism. (kiyalongevity.com)
Survive2
  • The complex environmental-sensory system allows B. fragilis to survive/adapt in the ever-changing human gut microbiome. (wikipedia.org)
  • B. fragilis has many mechanisms in place to survive its environment, which makes it a tricky microorganism to kill. (microchemlab.com)
Cells1
  • Caco-2 cells were treated with B. fragilis and its OMVs (180 and 350 µg/ml). (celljournal.org)
Significantly2
  • B. fragilis significantly decreased TLR2 and slightly increased TLR4 mRNA levels in Caco-2 cell line. (celljournal.org)
  • Furthermore, B. fragilis and its OMVs significantly increased and decreased IFNᵧ concentration, respectively. (celljournal.org)
Important2
  • Comparison of the structures of the new protein with those recently reported for N-acetyl-L-ornithine transcarbamylase indicates that amino acid residue 90 (B. fragilis numbering) plays an important role in conferring substrate specificity for N-succinyl-L-ornithine versus N-acetyl-L-ornithine. (nih.gov)
  • B. fragilis D‐lactate dehydrogenase (BfD‐LDH) is an important enzyme which catalyzes the conversion of D‐lactate to pyruvate and regulates anaerobic glycolysis. (chemaxon.com)
Human gut1
  • Genetic determinants of in vivo fitness and diet responsiveness in multiple human gut Bacteroides ," Science, doi:10.1126/science.aac5992, 2015. (the-scientist.com)
Expression1
  • 1. This protein is Bacteroides fragilis, protein from E.coli expression system maybe more suitable. (cusabio.com)
Role1
  • B. fragilis has been found to play a key role in food and nutrient breakdown during digestion, allowing for more efficient energy absorption for humans. (microchemlab.com)
Analysis1
  • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP346537BDP could indicate that this peptide derived from E.coli-expressed Bacteroides fragilis btfP. (cusabio.com)
Medical1
  • The " Bacteroides fragilis " healing sound from Sound-Pharmacy is an effective holistic medical practice with no side effects. (sound-pharmacy.com)