• The ability of many phages to remain in a bacterium in the form of a prophage and increase its adaptive potential, as well as to participate in the horizontal gene transfer between bacterial cells, a priori precludes their use in therapy due to safety concerns. (caister.com)
  • Bacteriophages (phages) are viruses that specifically attack and destroy bacteria. (bioquicknews.com)
  • Bacteriophages (phages) and their host bacteria follow predator-prey dynamics that drive co-evolution, resulting in the long-term persistence of both within ecosystems ( 7 ). (cdc.gov)
  • Dr. Jones, who led that initiative, said, "the UK's current phage source is limited, we need to establish a sustainable source of phages for the UK to maintain and expand phage therapy provision for NHS patients. (bacteriophage.news)
  • UK Phage Therapy will combine a clinical phage screening service with access to medical-grade phages (manufactured according to Good Manufacturing Practice [GMP]) to deliver sustainable phage therapy for the NHS. (bacteriophage.news)
  • CPI hopes to play a key role in developing GMP phage manufacturing, working with UK Phage Therapy and Fixed Phage to manufacture phages. (bacteriophage.news)
  • citation needed] Phages were discovered to be antibacterial agents and were used in the former Soviet Republic of Georgia (pioneered there by Giorgi Eliava with help from the co-discoverer of bacteriophages, Félix d'Hérelle) during the 1920s and 1930s for treating bacterial infections. (wikipedia.org)
  • From Feb 14th-16th, the who's who of the phage world is getting together to discuss everything from isolating phages from hospital wastewater to the role of the immune system in phage therapy! (phagedirectory.com)
  • This week, University of Vienna MSc student Jessica Neubauer explains why you should spend your Valentine's day cultivating your love of phages at the upcoming (virtual) Bacteriophage Therapy Summit! (phagedirectory.com)
  • Join the MICALIS Institute in Jouy-en-Josas, a south-east suburb of Paris, to explore the origin of spontaneous mutations in phages and bacteria. (phagedirectory.com)
  • My research interests are in the novel approaches to infection control in medical/agriculture/industrial settings using bacteriophages aka phages. (nottingham.ac.uk)
  • This DSMZ website will help to inform all those who are interested in phages and phage therapy. (dsmz.de)
  • What are bacteriophages (phages) and how do they work? (dsmz.de)
  • Bacteriophages, short form: phages (Greek: phagein = eat/swallow) are viruses in the wider biological sense. (dsmz.de)
  • The trial aims to determine whether the treatment is safe and if it reduces the amount of bacteria in trial volunteers, with investigators gathering data on safety and microbiologic activity, how the phages function in the body, how the therapy affects patients' lung function, and it s impact on overall quality of life. (umn.edu)
  • We cover the key points of the antibiotic resistance crisis and then explain the biological and evolutionary principles that support the use of phages, their interaction with the immune system, and a comparison with antibiotic therapy. (asm.org)
  • Bacteriophages (phages) are viruses capable of infecting and replicating within bacterial cells. (asm.org)
  • Felix d'Herelle first coined the term "bacteriophage" ( 4 ), literally meaning "bacterium eater," and began using phages to treat bacterial infections in human patients ( Fig. 1 ). (asm.org)
  • FIG 1 Timeline of major events in the history of research on phages, phage therapy, and antibiotics. (asm.org)
  • Control of bacterial diseases by bacteriophages (phages) is gaining more interest due to increasing antibiotic resistance. (jyu.fi)
  • To paraphrase the conclusion of Mallory's autopsy report: phage therapy is ideal to treat bacterial infections because phages are very specific and only kill the target bacteria, so they aren't dangerous or toxic. (cdc.gov)
  • His research led him to learn about bacteriophages (phages), naturally occurring viruses that have evolved to attack bacteria. (cdc.gov)
  • Bacteriophages, commonly known as phages, are viruses that selectively target and kill bacteria. (medscape.com)
  • These are called bacteriophages, or simply phages. (lu.se)
  • Bacterial viruses (bacteriophages) have significant impact on the evolution of bacteria and regulation of bacterial populations, including the microflora of the human body. (muni.cz)
  • Bacteriophages are viruses that can kill bacteria but are harmless to eukaryotic cells. (caister.com)
  • he studies immune shielding strategies for mitigating Covid-19 spread and how bacteriophage (bacterial viruses) therapy can treat antibiotic-resistant infections. (gatech.edu)
  • Bacteriophages are ubiquitous viruses, found wherever bacteria exist. (wikipedia.org)
  • Bacteriophages - viruses that kill bacteria-were successfully used for the first time to treat an antibiotic-resistant Mycobacterium abscessus lung infection to allow a cystic fibrosis patient to receive a life-saving lung transplant. (outbreaknewstoday.com)
  • Human waste is a rich source of organisms called bacteriophages - known as 'hunt and kill viruses' for their ability to bind to bacteria and destroy them. (abc.net.au)
  • The cocktail contains four bacteriophages (viruses that kill or neutralize bacteria) that target Pseudomonas aeruginosa , a multidrug-resistant bacterium that colonizes the lungs of CF patients and is the most common cause of CF exacerbations. (umn.edu)
  • The therapeutic use of bacteriophages, viruses that infect and kill bacteria, is well suited to be part of the multidimensional strategies to combat antibiotic resistance. (asm.org)
  • Bacteriophage are naturally occurring viruses that are highly specific for the bacterial hosts they infect. (businesswire.com)
  • Viruses of bacteria, bacteriophages, specifically infect their bacterial hosts with minimal effects on the surrounding microbiota. (jyu.fi)
  • Bacteriophages are good viruses! (abc-oriental-rug.com)
  • Bacteriophages are viruses that only attack bacteria. (abc-oriental-rug.com)
  • One type of bacteriophage, called T4, is one of nature's most efficient viruses and could offer a cheaper, safer, and more efficient gene therapy technique, according to a new study published in the journal Nature Communications . (inverse.com)
  • It is a fantastic recognition of the work that people in our lab have been doing for many years: first on protein synthesis, antibiotics targeting it and antibiotic resistance mechanisms that counter the antibiotics - and more recently, on bacterial viruses, bacteriophages. (lu.se)
  • [ 2 , 3 ] We are relatively ignorant of the functional and structural contributions of microorganisms outside of gut bacteria, with only a handful of publications looking at the gut virome (viruses and bacteriophages), mycome (fungi) and other micro-eukaryotes including protozoa. (medscape.com)
  • Assessment of the microbiome during bacteriophage therapy in combination with systemic antibiotics to treat a case of staphylococcal device infection, by Andre Mu et al. (phagedirectory.com)
  • Pioneered in Europe before the advent of antibiotics, bacteriophages, like Body Ecology's EcoPhage, selectively target specific, harmful bacteria while leaving beneficial microbes to flourish! (bodyecology.com)
  • Bacteriophages , like our EcoPhage , selectively target harmful bacteria (like E. coli ), and completely wipe them out (this was pioneered in Europe before the advent of antibiotics) 2,3,4 , leaving beneficial microbes to flourish, supporting the growth of beneficial bacteria and protecting against future infection. (bodyecology.com)
  • The discovery of penicillin in 1928 began the golden age of antibiotics, which pushed aside progress in treating infections with bacteriophages. (virology.ws)
  • Although phage therapy was first implemented almost a century ago, it was brought to a standstill after the successful introduction of antibiotics. (asm.org)
  • Finally, we discuss the benefits of phage therapy beyond the clinical perspective, including opportunities for scientific outreach and effective education, interdisciplinary collaboration, cultural and economic growth, and even innovative use of social media, making the case that phage therapy is more than just an alternative to antibiotics. (asm.org)
  • Background curves represent a qualitative measure of the overall interest, research, and use of phage therapy (yellow) and antibiotics (blue), showing how the introduction of antibiotics and the critical review of the early phage therapy studies coincided to bring phage therapy research and development to an almost complete standstill around the 1940s. (asm.org)
  • Also called phage therapy, it was developed in Eastern Europe in the early 20th century but largely dropped out of sight after antibiotics came on the market. (politico.com)
  • This type of therapy to destroy disease-causing bacteria may be useful as an alternative to antibiotics to fight antibiotic resistance or in conjunction with antibiotics to fight certain diseases. (abc-oriental-rug.com)
  • In the future, phage therapy may be used alone to eliminate antibiotic-resistant bacteria, or together with antibiotic therapy in cases where antibiotics still work. (bvsalud.org)
  • Stafford and his team discovered that the feces of several endangered animals harbored bacteriophages capable of killing bacterial strains resistant to antibiotics. (medscape.com)
  • A patient allergic to antibiotics showed significant improvement after treatment with several antistaphylococcal bacteriophage preparations. (medscape.com)
  • Used already in much genetic research, bacteriophage therapy was where the bacteriophage was used for the treatment of pathogenic bacterial infections. (cosmeticsdesign-europe.com)
  • With the rise of antibiotic-resistant infections, however, researchers have renewed their interest in phage therapy. (bioquicknews.com)
  • In limited cases, patients with life-threatening multidrug-resistant bacterial infections have been successfully treated with experimental phage therapy after all other alternatives were exhausted. (bioquicknews.com)
  • Rogelio Rodriguez Gonzalez passed his thesis proposal "Computational models to study phage therapy efficacy in multi-drug resistant Pseudomonas aeruginosa infections'' and was officially admitted for his PhD candidacy. (gatech.edu)
  • Bacteriophage (phage) therapy has the potential to transform our approach to treating bacterial infections. (bacteriophage.news)
  • As reported in the Mail on Sunday , phage therapy was recently made available to ten patients with diabetes in Edinburgh and Glasgow who were suffering from difficult-to-treat foot infections, with promising results. (bacteriophage.news)
  • Dr. Clare Trippett, Chief Technologist at CPI, said, "phage therapy is emerging as a powerful tool in the fight against antimicrobial resistance and treating bacterial infections. (bacteriophage.news)
  • This theme is highly relevant for potential clinical use of bacteriophages to treat infections by antibiotic resistant infectious bacteria. (tudelft.nl)
  • The Westmead Institute for Medical Research (WIMR) laboratory that Dr Lin is part of is the first in Australia to run a clinical trial of phage therapy for people with superbug infections. (abc.net.au)
  • SAN DIEGO & RICHMOND, Va. & LJUBLJANA, Slovenia & SYDNEY--( BUSINESS WIRE )--AmpliPhi BioSciences Corporation (OTCQB:APHB), a global leader in developing bacteriophage-based antibacterial therapies to treat drug resistant infections, today announced that M. Scott Salka has been appointed as the new CEO. (businesswire.com)
  • With a strong proprietary technology platform, first-in-class cGMP manufacturing capabilities and excellent lead pipeline candidates for addressing a major global health problem, AmpliPhi is strongly positioned to bring new therapies for treating deadly bacterial infections to market. (businesswire.com)
  • This dataset consists of three phage therapy experiments to prevent Flavobacterium columnare infections in rainbow trout. (jyu.fi)
  • We focus on (recurrent) UTI due to (particularly) resistant micro-organisms (BRMO), UTI in patients after renal transplantation, the role of the microbioma and complications of antibiotic therapy such as Clostridioides difficile infections. (lumc.nl)
  • Antimicrobial peptides (AMPs) and bacteriophages may offer a solution for treatment of drug-resistant infections in this era of antimicrobial resistance. (lumc.nl)
  • Promising strategies including bacteriophages and antimicrobial peptides are being tested for their efficacy against biofilm associated infections caused by different pathogens. (lumc.nl)
  • Innovative strategies like antimicrobial peptides and bacteriophages are urgently needed to improve outcome for patients with these complex infections. (lumc.nl)
  • d'Herelle suggested that the microscopic particles he called bacteriophages could be used to treat bacterial infections in humans and animals. (abc-oriental-rug.com)
  • Expansion of Human Microbiome-based Therapies: Several companies are developing microbiome-based therapies for a range of diseases and conditions, including cancer, autoimmune diseases, and infections. (biospace.com)
  • Constructing and Characterizing Bacteriophage Libraries for Phage Therapy of Human Infections. (cdc.gov)
  • Dr. Jacopo Marchi joined the Weitz Group where he'll work to advance bacteriophage therapy research. (gatech.edu)
  • In July 2021, the European Pharmacopoeia Commission launched work on new general chapter on phage therapy active substances and medicinal products for human and veterinary use, establishing harmonised quality standards for phage therapy products and providing a framework for their safe use in European countries. (muni.cz)
  • Focusing on human health and disease, the 4th Bacteriophage Therapy Summit is returning to help you advance your phage-based therapies through clinical development and commercialization beyond compassionate use. (phagedirectory.com)
  • AmpliPhi BioSciences Corporation (OTCQB:APHB) is a biotechnology company focused on the development and commercialization of novel bacteriophage-based antibacterial therapeutics. (businesswire.com)
  • The 4th Bacteriophage Therapy Summit , February 14-16, 2022 (online) is the definitive gathering for global phage experts. (phagedirectory.com)
  • Discussions in professional societies such as ESCMID Study Group for Non-traditional Antibacterial Therapy -ESGNTA are currently underway on setting the rules for production and safety of the use of bacteriophage preparations. (muni.cz)
  • Read the blog below authored by Diane Shader Smith, to learn more about antimicrobial resistance and the importance of investing in innovative treatments like phage therapy. (cdc.gov)
  • This is to discuss the recent documentary, Salt in My Soul, which follows Mallory Smith's life with cystic fibrosis and attempts to get phage therapy. (phagedirectory.com)
  • Panelists will be Will Battersby, director of the film, as well as Mallory's mother Diane Shader Smith, brother Micah Smith, and friend Maya Humes, as well as phage therapy scientist Ben Chan, Steffanie Strathdee, and Gunnar Esiason, a cystic fibrosis patient advocate. (phagedirectory.com)
  • The National Institutes of Health - supported trial is evaluating the experimental bacteriophage cocktail WRAIR-PM-CF1 in cystic fibrosis (CF) patients. (umn.edu)
  • Successful adjunctive use of bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa infection in a cystic fibrosis patient. (ucsd.edu)
  • This necessitates the use of alternatives such as bacteriophages in curbing zoonotic pathogens. (nih.gov)
  • Bacteriophage biocontrol of plant pathogens: fact or fiction? (cdc.gov)
  • Bacteriophage therapy represents a novel way to control the growth of plant-based bacterial pathogens. (cdc.gov)
  • Phage therapy, like other antibiotic alternatives, show great promise in many different applications including as treatment for extremely drug resistant pathogens, a potential decolonization method for patients carrying resistant germs, and potentially, the prevention of pathogen contamination in sterile devices. (cdc.gov)
  • In a systematic review of 15 systemic therapies in 48 patients, 27 of whom were children, immunoglobulins and biologicals, showed the best results. (medscape.com)
  • Bacteriophages' main advantages as therapeutics are their ability to target bacteria of certain strains or species, without any harmful effect on the rest of the bacterial microflora, as well as their self-limited propagation which is controlled by the availability of a sensitive host. (caister.com)
  • Adaptive Phage Therapeutics (APT) recently announced that the first patient in an early-stage clinical trial for its investigative bacteriophage therapy has been dosed. (umn.edu)
  • Since 2010, Mr. Salka has served as CEO of Aspyrian Therapeutics Inc., a company focused on developing near-infrared photoimmunotherapy (PIT) therapies. (businesswire.com)
  • Supported with a three-year, $1.2 million grant from the UCSD chancellor, the new Center for Innovative Phage Applications and Therapeutics (IPATH) is applying "the same principles of clinical evaluation and development to phage therapy that would be applied to any other therapeutic entity," says center co-director Robert Schooley, a physician and infectious disease specialist at UCSD. (nature.com)
  • We are national leaders in the delivery of Advanced Therapeutics through clinical trials and approved therapies to Australia children. (schf.org.au)
  • The strength and power of the translational pipeline of Advanced Therapeutics has never been more evident - our gene therapy trial success has changed the way we are able to treat children with Spinal Muscular Atrophy (SMA), our work in the gene therapy space has also been awarded the top project and idea by the National Health and Medical Research Council (NHMRC). (schf.org.au)
  • Technological Advancements: Advances in sequencing technologies and bioinformatics have made it easier to study the human microbiome, identify specific microbes, and develop targeted therapies. (biospace.com)
  • These therapies involve using live bacteria, bacteriophages, or microbial metabolites to modulate the microbiome and improve health outcomes. (biospace.com)
  • Advancements in Human Microbiome Research: Advances in human microbiome research are driving the development of new products and therapies. (biospace.com)
  • My research group at Delft University of Technology is built around the theme of microbe - bacteriophage interactions, and tackles important questions related to how bacteria become resistant to phage infection and how bacteriophages escape defense systems. (tudelft.nl)
  • Although this method shows promise, a recent paper by Gill and Abedon has shown that the complex bacteriophage-host interactions in the plant environment must be investigated further. (cdc.gov)
  • Bacteriophages, like EcoPhage selectively target specific, harmful bacteria while leaving beneficial microbes to flourish. (bodyecology.com)
  • The word, bacteriophage was coined by the person credited for their discovery, Felix D'Herelle, from the Greek 'phagein,' meaning 'to eat. (abc-oriental-rug.com)
  • Ciprofloxacin in combination with bacteriophage cocktails against multi-drug resistant Pseudomonas aeruginosa in ex vivo simulated endocardial vegetation models. (bvsalud.org)
  • George Eliava, a colleague of d'Herelle's at the Pasteur Institute, invited d'herelle to return to his native Georgia (Russia) and set up a 'bacteriophage' institute. (abc-oriental-rug.com)
  • Phage Therapy: Current Research and Applications (Edited by: Jan Borysowski, Ryszard Międzybrodzki and Andrzej Górski). (caister.com)
  • CPI is delighted to be collaborating with UK Phage Therapy and Fixed Phage on accelerating the translation of bacteriophage research into the clinic, enabling patients to access potentially life-saving phage therapies. (bacteriophage.news)
  • It was d'Hérelle who conducted much research into bacteriophages and introduced the concept of phage therapy. (wikipedia.org)
  • I am a member of the UK Food Safety Research Network and also the life member of Society For Bacteriophage Research and Therapy, India. (nottingham.ac.uk)
  • This review covers the underlying problems of antibiotic use and resistance associated with livestock farming in SSA, bacteriophages as a suitable alternative, what attributes contribute to making bacteriophages potentially valuable for SSA and recent research on bacteriophages in Africa. (nih.gov)
  • I have founded a national open source bacteriophage biobank ( www.fagenbank.nl ) that can serve as a resource for phage therapy research. (tudelft.nl)
  • As part of the Obama administration's National Action Plan for Combating Antibiotic Resistant Bacteria, NIH distributed $5 million to 24 research projects that are using unconventional, sometimes controversial therapies to try to beat bacteria. (politico.com)
  • Intellegens, a company applying machine learning (ML) to accelerate innovation in R&D, today announced that it has secured a £1.6m grant from Innovate UK, part of UK Research and Innovation (UKRI), to apply ML in the emerging field of oligonucleotide therapies. (news-medical.net)
  • Building on the extraordinary success of the national SMA trial, we are working with major industry partners, research institutes and the NSW government to develop our infrastructure, organisational frameworks and workforce in order to further expand on our capability to deliver these therapies to children nationally and internationally. (schf.org.au)
  • The resulting Eliava Institute has become a world leader in phage therapy, producing a great deal of research which, unfortunately, has basically been ignored in the West. (abc-oriental-rug.com)
  • While this work remains in the early stages, he thinks the new study could make waves in the research community and even inspire other teams to fast-track similar bacteriophage technologies. (inverse.com)
  • Although research centers in the United States, France, and former Soviet States never stopped conducting studies on phage therapy, this concept was only rediscovered in the 1980s, again drawing the interest of the global scientific community. (bvsalud.org)
  • They are seen as a possible therapy against multi-drug-resistant strains of many bacteria (see phage therapy). (wikipedia.org)
  • Within about two to three hours, Rao notes he can grow 100 trillion bacteriophage particles - pharmaceutical companies could accomplish this even faster with more complex equipment. (inverse.com)
  • Experimental bacteriophage therapy with the OMKO1 virus eliminated an antibiotic-resistant infection that was threatening the man's heart, according to a LiveScience article. (naturalnews.com)
  • Researchers at the University of California San Diego School of Medicine and their collaborators have now, for the first time, successfully applied phage therapy in mice for a condition that's not considered a classic bacterial infection: alcoholic liver disease. (bioquicknews.com)
  • We are delighted to announce that key infrastructure is being established for the provision of phage therapy in the UK through a new and exciting collaboration including UK Phage Therapy, technology innovation catalyst CPI, Fixed Phage and the University of Leicester. (bacteriophage.news)
  • Prof. Martha Clokie, University of Leicester, said, "we are enormously pleased by the support from the University of Leicester to build on our decades of expertise to establish a Phage Centre which we hope will act as a critical mass of expertise and biological resources to work across the UK to develop phage therapy for humans and other applications in a sustainable way. (bacteriophage.news)
  • AmpliPhi is collaborating with a number of leading organizations, including Intrexon Corporation (NYSE:XON), the U.S. Army, The Royal Brompton Clinic in London, UK and UK-based University of Leicester, to rapidly advance bacteriophage-based therapies. (businesswire.com)
  • More work is needed to fully understand the benefits of phage therapy. (cdc.gov)
  • The implication of this interplay between humans and microbes is that pharmacological therapies, nutrient modifications and associated interventions that are targeted at the host will also significantly impact on the gut microbiota. (medscape.com)
  • Bacteriophage are unaffected by antibiotic resistance and are able to disrupt bacterial biofilms. (businesswire.com)
  • Bacteriophage are able to penetrate biofilms and replicate locally to high levels, to produce strong local therapeutic effects. (businesswire.com)
  • The New York-based supplier had been conducting a series of studies on bacteriophage (live virus) therapy in blemish-prone skin, demonstrating the ability for a particular phage cocktail to reduce the levels of Cutibacterium acnes, a gram-positive bacterium linked to the skin condition of acne, as well as lower other inflammatory factors associated with this condition. (cosmeticsdesign-europe.com)
  • A bacteriophage is a live virus which parasitizes a bacterium by infecting it and reproducing inside. (cosmeticsdesign-europe.com)
  • Biocogent, therefore, had decided to invest in "embracing a more-than-century old therapy" ​ long discarded by many antibiotic-consuming nations - bacteriophage therapy - for "very precise and targeted" ​ work to target this bacterium. (cosmeticsdesign-europe.com)
  • The article is titled "Bacteriophage Targeting of Gut Bacterium Attenuates Alcoholic Liver Disease. (bioquicknews.com)
  • Bacteriophages can only multiply and grow inside a bacterium. (abc-oriental-rug.com)
  • A bacteriophage can be used to directly target certain disease-causing bacteria because each kind of phage will only attack a certain bacterium, not any other kinds of bacteria. (abc-oriental-rug.com)
  • Biofilm and Wax Moth (Galleria mellonella) Models Reveal New Insights into the Therapeutic Potential of Clostridium difficile Bacteriophages. (bodyecology.com)
  • Are antibiotic treatment and phage therapy contradictory? (dsmz.de)
  • Our results show that successful phage therapy treatment in the aquaculture setting requires optimisation of phage delivery methods in vivo. (jyu.fi)
  • Bacteriophage T4 therapy could therefore be engineered to benefit people with rare conditions, who often must seek out very expensive therapies - or may not have any treatment options at all. (inverse.com)
  • Compassionate use , which is also known as expanded access, is a potential pathway for patients with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product, like a drug, for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available. (cdc.gov)
  • Rao and his team think bacteriophage T4 could revolutionize gene therapy. (inverse.com)
  • One main issue is that these gene therapy vehicles can travel to the wrong places and damage healthy cells. (inverse.com)
  • Doctors typically give patients the gene therapy vehicle, referred to as a vector, by injection or through an IV. (inverse.com)
  • If it succeeds in trials, bacteriophage T4 could offer some distinct advantages over existing gene therapy methods, Rao says. (inverse.com)
  • Bacteriophage T4 may also prove safer than current gene therapy options. (inverse.com)
  • The unexpected ingredient in this potentially transformative therapy? (medscape.com)
  • To get therapies into the brain after a stroke, researchers are increasingly making use of the blood-brain barrier, which allows only certain molecules to pass from the blood into the brain. (news-medical.net)
  • A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)-;specialized molecules that can modulate RNA and alter protein production-;directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord. (news-medical.net)
  • Rao and his team can "mix and match" many types of molecules into bacteriophage T4 based on the specific condition being targeted in each patient and their genetic makeup. (inverse.com)
  • When Mallory received phage therapy via compassionate use on November 14, 2017, there was not one institution in the United States offering it. (cdc.gov)
  • The irreversible increase in drug-resistant bacteria is cause for concern and has created a new role for phage therapy, especially in cases where the alternatives to control the signs and symptoms of drug-resistant infectious processes have been exhausted. (bvsalud.org)
  • Evaluation of Bacteriophage-Antibiotic Combination Therapy for Biofilm-Embedded MDR Enterococcus faecium . (bvsalud.org)
  • What Can We Learn from a Metagenomic Analysis of a Georgian Bacteriophage Cocktail? (mdpi.com)
  • A century-old method using live virus bacteriophages has the potential to make its revival in skin care via formulations designed to target blemish-prone skin, says US supplier Biocogent. (cosmeticsdesign-europe.com)
  • Today's gene therapies have huge potential - they have worked in treating certain cancers , along with blood and vision diseases - but they can come with major downsides. (inverse.com)
  • Now, scientists think that a type of virus with an appetite solely for bacteria - known as a bacteriophage - could overcome these obstacles. (inverse.com)
  • A catalyst for this collaboration has been the pioneering work of Dr. Josh Jones who has helped pave the way to make phage therapy available to patients in the NHS. (bacteriophage.news)
  • Gene therapies work by manipulating the genes that cause or lead to certain diseases and restore cells' normal functioning. (inverse.com)
  • Now four universities have established phage therapy centers with others doing the work in a less formalized way. (cdc.gov)
  • Development of Host Immune Response to Bacteriophage in a Lung Transplant Recipient on Adjunctive Phage Therapy for a Multidrug-Resistant Pneumonia. (ucsd.edu)
  • Early clinical experience of bacteriophage therapy in 3 lung transplant recipients. (ucsd.edu)
  • Our experience with phage therapy started after Mallory was rejected as a candidate for a double lung transplant. (cdc.gov)
  • Bacteriophage resistance occurred in distinct clades along both internal and external branches of the cholera phylogeny. (cdc.gov)