They determined the relationship between Salmonella phage P22 and coliphage lambda, and discovered that bacteriophage genomes had a modular structure. (wikipedia.org)
Whole genome sequencing of bacteriophages suitable for biocontrol of pathogens in food products is a pre-requisite to any phage-based intervention procedure. (biomedcentral.com)
This phage was sequenced and analysis of its 157,785 bp circular dsDNA genome revealed a number of interesting features. (biomedcentral.com)
At the nucleotide level ΦSH19 is highly similar to phage Vi01 (80-98% pairwise identity over the length of the genome), with the major differences lying in the region associated with host-range determination. (biomedcentral.com)
Here, we reported the first Oceanospirillum phage, vB_OliS_GJ44, which was assembled into a 33,786 bp linear dsDNA genome, which includes abundant tail-related and recombinant proteins. (biomedcentral.com)
A search of human gut metagenomes for circular contigs encoding phage hallmark genes resulted in the identification of 3738 apparently complete phage genomes that represent 451 putative genera. (biomedcentral.com)
Comparative genomic analysis of the three candidate phage families revealed features without precedent in phage genomes. (biomedcentral.com)
Analysis of phage genomes identified in whole-community human gut metagenomes resulted in the delineation of at least three new candidate families of Caudovirales and revealed diverse putative mechanisms underlying phage-host interactions in the human gut. (biomedcentral.com)
The rapid growth of the public whole-community metagenomic data offers the opportunity to identify numerous novel phage genomes lurking in metagenomes. (biomedcentral.com)
Tailed dsDNA phages encapsidate their genome as a linear molecule, but depending on the terminal genomic arrangement, many complete phage genomes assemble into a "circular" contig (i.e., a contig with direct terminal repeats) [ 12 ]. (biomedcentral.com)
Thus, circularity can be used as one feature to identify putative complete phage genomes in viromes and metagenomes. (biomedcentral.com)
Double-stranded2
Molecular analyses indicated that FC, FP, and FQ contained double-stranded DNA genomes, of sizes similar to bacteriophage P22, and distinct recognition sites for the restriction endonucleases HaeIII and HindIII. (ejbiotechnology.info)
lt;p>Tailed bacteriophages containing double-stranded DNA phylogenetically represent the oldest and most widespread group of bacterial viruses. (crie.ru)
Phages2
The use of virulent bacteriophages (phages) as biological control (biocontrol) agents against bacterial pathogens is an expanding field of research aimed at producing sustainable solutions for the control of these pathogens, and to circumvent problems such as those associated with the development of multidrug-resistant bacteria [ 1 ]. (biomedcentral.com)
lt;p>Bacteriophages (or phages) are viruses that infect bacteria and use their resources to reproduce. (crie.ru)
Capsids3
Finally, we comment on a combined AFM/ fluorescence application to study the influence of crowding on GFP packed within individual P22 bacteriophage capsids . (bvsalud.org)
In the study presented, we adapted this technique for much smaller objects, namely the capsids of phiKZ-like bacteriophages. (crie.ru)
Combined with the eight environmental viral contigs from metagenomics, this study helps fill the gap in our understanding of the isolation, genomic and evolutionary development of Oceanospirillum bacteriophages and provides new insights into the interactions between hosts and bacteriophages for these important marine hydrocarbon-degrading microbial populations. (biomedcentral.com)
They contain most or all of the molecular machinery necessary for efficient and specific packaging of viral genomes, escape from an infected cell, survival of transfer to a new host cell, attachment, penetration, and initiation of a new replication cycle. (basicmedicalkey.com)
A variety of techniques have been used to examine plant viral genomes, the functions of virus-encoded proteins, plant responses induced by virus infection and plant-virus interactions. (springer.com)
Biocontrol1
Thus, accidental infection by the original host can be avoided when bacteriophage lysates are used in biocontrol protocols. (ejbiotechnology.info)
Proteins2
Of the three tail spikes, two have protein domains associated with the pectate lyase family of proteins (Tsp2) and P22 tail spike family (Tsp3) with the prospect that these enable Salmonella O antigen degradation. (biomedcentral.com)
Of note, the genes encoding these effectors and immunity proteins are widely distributed in Salmonella genomes, suggesting a relevant role in interbacterial competition and virulence. (frontiersin.org)
Gene4
They showed that the expression of bacteriophage lambda's late genes was controlled by the product of the Q gene, late in the life cycle of the virus by the site. (wikipedia.org)
Marine bacteriophages play key roles in the community structure of microorganisms, biogeochemical cycles, and the mediation of genetic diversity through horizontal gene transfer. (biomedcentral.com)
The shell of a nonenveloped virus with even a very small genome must therefore contain a large number of identical protein subunits-at least 60, if the coat-protein gene is to use up less than 25% of the coding capacity in the enclosed nucleic acid. (basicmedicalkey.com)
Post-doctoral years with Mike Levine: P22 and the Int gene -- Scene 4. (cshl.edu)
Genes2
A single site in the genome was used by Q to activate all of the late genes, which were transcribed into a single, long messenger RNA. (wikipedia.org)
These studies showed that P100 had no undesirable genes within its genome, and caused no ill effects when administered to rats. (biomedcentral.com)
Viruses3
Enveloped viruses have, in their lipid bilayer, an impermeable barrier between their genomes and the outside environment, reducing the need for continuity of any protein layer. (basicmedicalkey.com)
Atomic Force Microscopy of Viruses: Stability, Disassembly, and Genome Release. (bvsalud.org)
Ideally, bacteriophages of pathogenic bacterial hosts should be polyvalent to be able to replicate in an alternative nonpathogenic bacterium. (ejbiotechnology.info)
Details1
However, until now there has been no isolate of an Oceanospirillum bacteriophage, and so details of their metagenome has remained unknown. (biomedcentral.com)
Found1
By transmission electron microscopy (TEM) observation, the bacteriophages were found to belong to the order Caudoviridae. (ejbiotechnology.info)
Structure1
For the structure of any virus particle, a central constraint is that the information needed to specify its macromolecular components must not exhaust the genetic capacity of the packaged genome. (basicmedicalkey.com)
Food2
Only in the last few years has there been an extension of lab-based trials into the food production environment, where perhaps the best example is the recognition of the efficacy and the granting of 'generally recognized as safe' (GRAS) status to bacteriophages targeting Listeria monocytogenes by the United States Food and Drug Administration [ 11 ]. (biomedcentral.com)
Bacteriophages for potential food safety. (umd.edu)
Potential1
We have isolated new bacteriophages of the serovar Choleraesuis with various potential applications in relation to this pathogenic bacterium. (ejbiotechnology.info)
Region1
From 15 wastewater samples, collected at different sites in the V Region in Chile, we selected three bacteriophages (FC, FP, and FQ) capable of productively infecting Salmonella enterica serovar Choleraesuis. (ejbiotechnology.info)
Salmonella3
Genome ejection proteins are required to facilitate transport of bacteriophage P22 double-stranded DNA safely through membranes of Salmonella. (nih.gov)
A species of temperate bacteriophage in the genus P22-like viruses, family PODOVIRIDAE , that infects SALMONELLA species. (nih.gov)
Especie de bacteriófago temperado del genero de virus similares a P22, familia PODOVIRIDAE, que infecta a especies de Salmonella. (bvsalud.org)
Virulent bacteriophage and type species of the genus T4-like phages, in the family MYOVIRIDAE. (lookformedical.com)
Virulent bacteriophage and type species of the genus T7-like phages, in the family PODOVIRIDAE, that infects E. coli. (lookformedical.com)
Infects2
A bacteriophage is type of virus, which can infects bacteria, either kill a bacterial cell or integrate its DNA into the host bacterial chromosome. (scialert.net)
Virulent bacteriophage and sole member of the genus Cystovirus that infects Pseudomonas species. (lookformedical.com)
Viruses1
Virus-like particles (VLPs) are self-assembled protein structures that mimic native viruses or bacteriophages but lack the replicative material. (bvsalud.org)
BACTERIOPHAGE T7) are called "dependent virulent" because they depend on continued bacterial metabolism during the lytic cycle. (lookformedical.com)
Recombinant2
Here, we report molecular weight (MW) distributions measured for HAdV5 and for 11 recombinant AdV vectors with genomes of varying lengths. (nih.gov)
Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell. (wikidata.org)
Protein1
Human adenovirus 5 (HAdV5) contains over 2500 protein molecules and has a 36 kbp genome. (nih.gov)
Pathogenic1
In this study we characterized thirteen Escherichia coli strains from patients with IBD by comparative genomic hybridization employing a microarray based on 31 sequenced E. coli genomes from a wide range of commensal and pathogenic isolates. (biomedcentral.com)