• Lactobacillus plantarum and Lactococcus lactis were separately able to detoxify aflatoxin B_1 in solutions. (tubitak.gov.tr)
  • Cloning and expression of the gene for lactacin F, a Lactobacillus acidophilus bacteriocin, using an amino acid sequence-derived DNA probe. (ncsu.edu)
  • CLONING, EXPRESSION, AND NUCLEOTIDE-SEQUENCE OF THE LACTOBACILLUS-HELVETICUS-481 GENE ENCODING THE BACTERIOCIN HELVETICIN-J. JOURNAL OF BACTERIOLOGY, 172(11), 6339–6347. (ncsu.edu)
  • Lactobacillus helveticus 481 produces a 37-kDa bacteriocin called helveticin J. Libraries of chromosomal DNA from L. helveticus were prepared in lambda gt11 and probed for phage-producing fusion proteins that could react with polyclonal helveticin J antibody. (ncsu.edu)
  • Lactobacillus, Lactococcus, Leuconostoc, and Enterococcus are the most common genera of LAB tested towards L. garvieae either in in vitro or in vivo assays, and the obtained results are promising. (ac.ir)
  • Like other lactobacilli, Lactobacillus rhamnosus A also releases acids, bacteriocins, and hydrogen peroxide which inhibit the growth of pathogens. (nexabiotic.com)
  • Methods are described for increasing levels of healthy vaginal bacteria by treating the vaginal mucosa with bacteriocins derived from Lactobacillus paragasseri, Lactobacillus gasseri, and other bacterial strains. (justia.com)
  • The bacteriocins are surprisingly advantageous as being selectively active against Lactobacillus iners but relatively inactive against H2O2-producing Lactobacillus species. (justia.com)
  • Nisin is the only bacteriocin approved by US-FDA for commercial application in food products. (researchsquare.com)
  • Nisin is a natural antimicrobial peptide used as food preservative produced by Lactococcus lactis , that inhibits the outgrowth of spores, the growth of a variety of Gram-positive and Gram-negative bacteria. (usp.br)
  • Lactococcus lactis ATCC 11454 was developed in a rotatory shaker (30°C/36 h/100 rpm) in diluted skimmed milk and nisin expression, growth parameters and media components were also studied. (usp.br)
  • Only one bacteriocin (nisin from Lactococcus lactis) has been used commercially, but it has had a variety of applications (food safety and preservation, animal growth promotion, industrial fermentations and human disease treatment). (usda.gov)
  • Because resistance has stymied nisin use, researchers have screened a variety of bacteriocins to see if better ones that remain active for longer periods of time can be found. (usda.gov)
  • The green consumerism is the basis for the development of alternative approaches for food preservation, like the use of natural compounds (essential oils, lysozyme, nisin and other bacteriocins, chitosan) and nonthermal treatments (high hydrostatic pressures, homogenization, microwave, irradiation). (eurekaselect.com)
  • Numerous bacteriocin have been reported to be produced by probiotic microorganisms namely Acidophilin, Bifidin and Nisin ( Klaenhammer, 1988 ). (scialert.net)
  • Nisin is part of a class of antimicrobial peptides known as bacteriocins, which are naturally produced by bacteria to defend against competitors. (dachengpharma.com)
  • C. Nájera-Domínguez and N. Gutiérrez-Méndez, "Autolytic and Proteolytic Properties of Strains of Lactococcus lactis Isolated from Different Vegetables, Raw-Milk Cheeses and Commercial Starter Cultures," Food and Nutrition Sciences , Vol. 4 No. 11A, 2013, pp. 21-26. (scirp.org)
  • 1992. Identification and characterization of two bacteriocin-producing strains of Lactococcus lactis isolated from vegetables. (unl.edu)
  • Bacteriocins are ribosomally synthesized proteinaceous compounds produced by bacteria to protect themselves as well as to competitively colonize in the gut through elimination of undesirable organisms. (researchsquare.com)
  • Bacteriocins are ribosomally synthesized antimicrobial peptides produced by bacteria, which have the ability to kill or inhibit other bacteria. (ucc.ie)
  • The bacteriocins are very small ribosomally synthesized peptide molecules secreted by archea, gram-positive and some of gram-negative bacteria (Klaenhammer et al. (bbrc.in)
  • The molecular approach of using Geneious Prime software and protein prediction data base for characterization of bacteriocin is novel and predicts " KSSAYSLQMGATAIKQVKKLFKKWGW " as peptide responsible for antimicrobial activity. (researchsquare.com)
  • Thus, understanding the mechanisms by which bacteriocins exert their sporostatic/sporicidal activity against bacterial spores will ultimately facilitate their optimal use in food. (ucc.ie)
  • Fish lactococcosis, particularly caused by Lactococcus (L.) garvieae, has become a serious recurring bacterial disease in farmed fish, and due to the disease pathogenesis, its treatment is often temporary and, in some cases, ineffective. (ac.ir)
  • Most surprisingly, one-third of pneumococcal genomes also possessed a cassette encoding a novel circular bacteriocin that we called pneumocyclicin, which shared a similar genetic organisation to well-characterised circular bacteriocin cassettes in other bacterial species. (biomedcentral.com)
  • Given that the producer and target strains are often of the same bacterial species, the bacteriocins are largely believed to be involved in competition for limited resources within an ecological niche, but they may also be contributing to the maintenance of microbial diversity at a population level [ 14 - 16 ]. (biomedcentral.com)
  • This is another important reason to study bacteriocins and tap their therapeutic potential to combat drug resistant bacterial infections. (bbrc.in)
  • Aggregation-Promoting Factor Production in Lactococcus lactis ssp. (com.hr)
  • Dos 20 isolados, 19 apresentaram halos de inibição sobre as três bactérias patogênicas, com zonas de inibição de 2 a15 mm, e os maiores halos foram formados por Lactococcus lactis ssp lactis sobre S. enterica e S. aureus. (bvsalud.org)
  • Of 20 bacteria isolated, 19 showed inhibition halos on the three pathogenic bacteria with diameter of 2 to 15 mm, and the largest halos were formed by Lactococcus lactis ssp lactis on S. enterica and S. aureus. (bvsalud.org)
  • LAB that are usually designated as generally recognized as safe (GRAS) status in foods can also exert a biopreservative effect against other microorganisms as a result of competition for nutrients and/or of the production of antagonistic compounds such as organic acids, diacetyl, acetoin, hydrogen peroxide, antibiotics, and bacteriocins (Schillinger et al. (e-fas.org)
  • J. Ramírez-Nunez, R. Romero-Medrano, G. V. NevárezMoorillon and N. Gutiérrez-Méndez, "Effect of pH and Salt Gradient on the Autolysis of Lactococcus lactis Strains," Brazilian Journal of Microbiology, Vol. 42, No. 4, 2011, pp. 1495-1499. (scirp.org)
  • These LAB produced bacteriocin-like inhibitory substances (BLIS) and proteinases. (edu.mk)
  • Bacteriocins from LAB are low molecular peptides which vary in their size, post-translation modifications, stability and mode of action (Amortegui et al. (researchsquare.com)
  • Bacteriocins are small, ribosomally-synthesised antimicrobial peptides or proteins produced by bacteria to inhibit other bacteria, and the producer strain has a dedicated immunity system that protects it from its own bacteriocin. (biomedcentral.com)
  • Bacteriocins are powerful bactericidal peptides produced and secreted by a varied group of micro- organisms including yeast, protozoa and of course bacteria and they cause death and removal of non bacteriocin producing pathogenic bacteria. (bbrc.in)
  • These bacteriocin treatments offer more benefits over antibiotic therapies in present time as they are natural bioactive peptides having no side effects. (bbrc.in)
  • Dobson et al 2012 reviewed the role of antimicrobial peptides, or bacteriocins, produced by bacteria in establishing competitive exclusion of pathogenic strains. (drvitaminsolutions.com)
  • Abstract The longevity of mesophilic lactococci in dairy fermentations depends to a large extent on whether or not the strains carry effective phage-resistance mechanisms. (ncsu.edu)
  • Therefore, in the present study, a new human skin-derived Lactococcus paracasei strain, HS-05, was isolated, and its morphological characteristics were investigated. (springeropen.com)
  • In the experiment, two different strains of bacteria are used to make reduced-fat cheddar cheese: a strain of Lactococcus lactis and a strain of S. thermophilus . (wikipedia.org)
  • Bacteriocins also show additive/synergistic effects when used in combination with other treatments, such as heating, high pressure, organic compounds, and as part of food packaging. (ucc.ie)
  • Bacteriocins are a diverse group of compounds in terms of size, mode of action and immunity mechanisms, and are produced by both Gram-positive and Gram-negative bacteria. (biomedcentral.com)
  • Pathogens' inhibition was mostly mediated by the production of organic acids, but neutralization experiments strongly suggested the presence of additional antimicrobial compounds in probiotic culture supernatants such as the bacteriocin Lantibiotic B, whose gene was detected in the genome of B. longum KABP042. (frontiersin.org)
  • This work aimed to investigate the effect of dietary Lactococcus lactis and Bacillus subtilis on the immune responses, intestinal microbiota, and resistance to pathogens of Oscar, Astronotus ocellatus . (ij-aquaticbiology.com)
  • The study provides information about broad spectrum bacteriocin in native probiotic culture and paves a way towards its application in functional foods as biopreservative agents. (researchsquare.com)
  • Some bacteriocins have a broad spectrum, but many are highly selective and can only inhibit closely related species or strains. (usda.gov)
  • 2015) as well as synthesized by ribosomes with antimicrobial properties against various groups of microorganisms (Chikindas, et a., 2017).The activity of bacteriocins is influenced by temperature, pH, and composition of culture medium (Guinane et al. (bbrc.in)
  • Immunity proteins that sequester the bacteriocins from the cell membrane or expel them protect the bacteriocin-producing bacteria. (usda.gov)
  • Bacteriocin-sensitive bacteria can become resistant, but this characteristic is distinctly different from immunity. (usda.gov)
  • Pneumococci reside in the paediatric nasopharynx, where they compete for space and resources, and one competition strategy is to produce a bacteriocin (antimicrobial peptide or protein) to attack other bacteria and an immunity protein to protect against self-destruction. (biomedcentral.com)
  • The composition of the 'bacteriocin/immunity region' of the blp cassette was highly variable: one cassette possessed six bacteriocin genes and eight putative immunity genes, whereas another cassette had only one of each. (biomedcentral.com)
  • The potential of Bacteriocins as an alternate or adjuvant to antibiotics needs to be studied and made available to the medical community. (bbrc.in)
  • Recent trends suggest that if an effective alternate to antibiotics is not found quickly then the very existence of mankind could come under threat .The safety profile of bacteriocins is much superior to antibiotics. (bbrc.in)
  • The growth kinetic assay revealed 24 h of incubation to be optimum for bacteriocin production. (researchsquare.com)
  • With consumers becoming more concerned about the levels of chemical preservatives present in food, bacteriocins offer an alternative, more natural approach, while ensuring both food safety and product shelf life. (ucc.ie)
  • Bacteriocins represent one potential treatment as they may inhibit spores in the post-germination/outgrowth phase of the spore cycle. (ucc.ie)
  • This review will focus on the use of bacteriocins alone, or in combination with other innovative processing methods to control spores in food, the current knowledge and gaps therein with regard to bacteriocin-spore interactions and discuss future research approaches to enable spores to be more effectively targeted by bacteriocins in food settings. (ucc.ie)
  • Characteristics of phage abortion conferred in lactococci by the conjugal plasmid pTR2030. (ncsu.edu)
  • Transformants carrying pTRK135 produced a bacteriocin that was heat labile and exhibited an acitivity spectrum that was the same as that of helveticin J. (ncsu.edu)
  • E. H. E. Ayad, A. Verheul, J. T. M. Wouters and G. Smit, "Antimicrobial-Producing Wild Lactococci Isolated from Artisanal and Non-Dairy Origins," International Dairy Journal, Vol. 12, No. 2-3, 2002, pp. 145-150. (scirp.org)
  • N. Gutiérrez-Méndez, B. Vallejo-Cordoba, A. F. González-Córdova, G. V. Nevárez-Moorillon and B. RiveraChavira, "Evaluation of Aroma Generation of Lactococcus lactis with an Electronic Nose and Sensory Analysis," Journal of Dairy Science, Vol. 91, No. 1, 2008, pp. 49-57. (scirp.org)
  • This paper is a review of MDR (Multiple rug Resistance) related issues which have become a global problem and on the possible role of bacteriocins as an effective option for fighting against MDR disease causing bacteria. (bbrc.in)
  • Bonhi K. L. R, Imran S. Role of Bacteriocin in Tackling the Global Problem of Multi-Drug Resistance : An Updated Review. (bbrc.in)
  • We analysed a collection of 336 diverse pneumococcal genomes dating from 1916 onwards, identified bacteriocin cassettes, detailed their genetic composition and sequence diversity, and evaluated the data in the context of the pneumococcal population structure. (biomedcentral.com)
  • Infection by prolate phage c2 and small isometric phage p2 of derivatives of Lactococcus lactis LM2301 with or without pTR2030, and infection by small isometric phage o31 of derivatives of L. lactis NCK202 with or without pTR2030 was studied. (ncsu.edu)