• Bacterial pathogens that can cause ANI originating from humans include the group-A streptococci, Staphylococcus-aureus, and Mycobacterium- tuberculosis. (cdc.gov)
  • Fungal pathogens that can cause ANI include Aspergillus and Zygomyces species. (cdc.gov)
  • The most commonly encountered mycobacterium pathogens, however, are species of MAC. (wcponline.com)
  • Finally, we discuss the opportunities and challenges of autophagy manipulation in improving therapeutics and vaccines against bacterial pathogens. (frontiersin.org)
  • Here, we review the many functions of autophagy in bacterial infections with a focus on macrophages, the first line of host defenses, and the replicative niche of numerous pathogens. (frontiersin.org)
  • Among the Gram-negative cocci, two specific bacterial species stand out as important human pathogens. (livestrong.com)
  • A complete list of bacterial human pathogens numbers in the hundreds. (livestrong.com)
  • Although the majority of microbes succumb to the microbicidal environment within the phagolysosome, some pathogens (including Mycobacterium tuberculosis and Salmonella Typhimurium ) can survive and replicate within this harsh environment ( 11 , 12 ). (frontiersin.org)
  • In contrast, some bacterial pathogens (including Listeria monocytogenes and Shigella flexneri ) have mechanisms to escape from the phagosome and proliferate in the cytosol ( 13 ). (frontiersin.org)
  • Targeting of bacterial pathogens by the autophagy machinery is often mediated by ubiquitination, a posttranslational modification ( 16 , 17 ). (frontiersin.org)
  • This process of "molecular mimicry" may help explain why bacterial human pathogens, many of which were at one time easily treatable with antibiotics, have re-emerged in recent years as highly infectious public health threats, according to the study appearing in the online journal PLoS ONE , published by the Public Library of Science. (sciencedaily.com)
  • Using genomic sequencing, the spelling out of billions of genetic instructions stored in DNA, the study identified several methyltransferase protein families that are very similar in otherwise very distantly related human bacterial pathogens. (sciencedaily.com)
  • In general, these bacterial pathogens are considered "highly clonal," meaning that the overall gene content of each species is very similar. (sciencedaily.com)
  • Upon infection, bacterial pathogens dump more than 200 proteins into human macrophage cells called 'effector proteins. (sciencedaily.com)
  • The progressive increase in resistances to antibiotics in bacterial human pathogens is a worldwide public health concern. (mdpi.com)
  • The aim of this topic is to provide an up-to-date overview of the current situation of antimicrobial resistances in human bacterial pathogens. (mdpi.com)
  • The Reference Bacteriology Laboratory offers identification of selected bacterial pathogens from human sources which are of public health importance. (in.gov)
  • And she gained a new appreciation for the myriad other types of intracellular bacteria, a diverse group that includes many medically significant pathogens such as Salmonella , Listeria, and Chlamydia , as well as the causative agents of tuberculosis and leprosy. (the-scientist.com)
  • Our work investigates the prevalence of resistance in bacterial pathogens, and models covariates relating to the spread of AMR, including global antibiotic consumption and household crowding. (ox.ac.uk)
  • Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019. (emedinexus.com)
  • Mycobacterium tuberculosis (MTB) and Mycobacterium avium complex (MAC) are two distinct types of bacteria that can cause infections in the lungs and other parts of the body. (medicalnewstoday.com)
  • Tuberculosis is a highly contagious disease caused by the bacteria Mycobacterium tuberculosis (M. tuberculosis) , which is believed to be present in the nature for at least 15,000 years. (news-medical.net)
  • Certain species of Clostridium bacteria induce disease by producing powerful toxins. (livestrong.com)
  • A related species called Bacillus cereus causes food poisoning mediated by toxins the bacteria produce. (livestrong.com)
  • Researchers at Albert Einstein College of Medicine of Yeshiva University have found two novel ways of killing the bacteria that cause tuberculosis (TB), a disease responsible for an estimated two million deaths each year. (rdworldonline.com)
  • The GlgE research, done in collaboration with Dr. Stephen Bornemann at the John Innes Centre (UK), revealed a previously unknown enzymatic pathway by which TB bacteria convert the sugar trehalose (consisting of two glucose molecules) into longer sugar molecules known as alpha glucans - building blocks that are essential for maintaining bacterial structure and for making new microbes through cell division. (rdworldonline.com)
  • Sure enough, when the researchers inhibited GlgE, the bacteria underwent "suicidal self-poisoning": a sugar called maltose 1-phosphate accumulated to toxic levels that damaged bacterial DNA, causing the death of TB bacteria grown in Petri dishes as well as in infected mice. (rdworldonline.com)
  • Similar methyltransferase proteins are found in other highly infectious bacteria, including the pathogen Mycobacterium tuberculosis that causes Tuberculosis, a disease that results in more than 1 million deaths annually. (sciencedaily.com)
  • With many species of bacteria including Escherichia coli and Mycobacterium tuberculosis, PCR performed on plated colonies have been successful thereby reducing the assay time previously needed to isolated genomic DNA. (vin.com)
  • The most common acid-fast staining method for M. tuberculosis is the Ziehl-Neelsen stain method, in which a bacteria specimen is fixed, stained with carbol-fuchsin dye, and decolorized with an acid-alcohol mixture. (gideononline.com)
  • Similar ferredoxin encoding genes were identified across Mycobacterium species, including in the pathogenic M. tuberculosis and M. ulcerans , as well as in a wide range of other bacteria such as Rhodococcus and Streptomyces . (rsc.org)
  • November 28, 2022 - Dr. Christoph Grundner and CGIDR colleagues have discovered how nutrients traverse the fortress-like outer cell wall of Mycobacterium tuberculosis , shedding light on a longstanding mystery in the biology of the bacteria that causes tuberculosis, a potentially life-threatening disease primarily of the lungs. (seattlechildrens.org)
  • By contrast, obligate intracellular bacteria such as Chlamydia trachomatis and Mycobacterium leprae do, and this trait makes them a challenge to culture and study in the lab. (the-scientist.com)
  • These bacterial proteins could be used by the bacteria to help them escape their clearance. (plcontracts.com)
  • Dr Ioannis Nezis commented: "Our systems-level analysis has highlighted the complex interplay between host autophagy and bacteria to inspire future experimental studies to elucidate the detailed molecular mechanisms of autophagy in the pathogenesis of bacterial infections. (plcontracts.com)
  • Of these, nearly 8 million deaths were associated with the 33 species of bacteria examined. (emedinexus.com)
  • Amongst all the bacterial species evaluated, five bacteria namely Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae, Klebsiella pneumoniae, and Pseudomonas aeruginosa accounted for nearly 55% of deaths. (emedinexus.com)
  • When there is no evidence of person- tubes (160 mm size), followed by the slow- and rapid-growing bacteria from to-person transmission, it can be assumed introduction of 2 mL of tuberculosis 30 districts in Basra. (who.int)
  • The slow-growing that humans are infected with nontuber- (TB) broth to cover the lower portion of bacteria included: photochromogens, culous mycobacteria from environmen- the slant only. (who.int)
  • Examination of direct smears for acid fast bacilli is the widely used method for the detection of mycobacteria, but lacks the desired specificity and relatively large number of bacteria is needed for detection. (who.int)
  • A growing pool of evidence suggests that the current strains of M. tuberculosis is originated from a common ancestor around 20,000 - 15,000 years ago. (news-medical.net)
  • DNAs prepared from bacterial strains and animal tissues. (vin.com)
  • The unique inserts in CRISPR show virtually no similarity even between closely related bacterial strains which suggests their rapid turnover, on evolutionary scale. (biomedcentral.com)
  • Gene-based testing and nuclear amplification to identify the bacterial strains using DNA-based molecular techniques, such as GeneXpert [7]. (gideononline.com)
  • Maximum activity was observed on bacterial strains compared with fungal strains. (journaltocs.ac.uk)
  • Minimum inhibitory concentrations and minimum bactericidal and fungicidal concentrations of the seed oil varied between 3 to 10 mg/50 μL against all bacterial and fungal strains used in this study. (journaltocs.ac.uk)
  • Although metagenomic tools exist to classify strains in a metagenomic sample, most tools have been developed for more divergent species, and therefore cannot provide the sensitivity required to disentangle strains within closely related bacterial species such asM. (9lib.org)
  • tuberculosis strains in whole genome sequencing data. (9lib.org)
  • Here we report that members of the family, ivermectin, selamectin, and moxidectin, are bactericidal against mycobacterial species, including multidrug-resistant and extensively drug-resistant clinical strains of Mycobacterium tuberculosis. (nih.gov)
  • Patients have been reported to present with symptoms and signs of bacterial tracheitis and multiorgan failure due to exotoxin-producing strains of Staphylococcus aureus or Streptococcus pyogenes in the trachea. (medscape.com)
  • Results obtained from Restriction fragment length polymorphism typing show that the mahority of circulating Mycobacterium tuberculosis strains in Sri Lanka belong to a limited number of families, but the degree of IS6160 DNA polymorphism among strains were high. (who.int)
  • In bacterial isolates of prisoners and ex-prisoners from the general population, there were 2 strains, which had identical banding patterns, while there were clear similarities between several isolates. (who.int)
  • More than 68 percent had less than 5 copies of the IS sequence suggesting that our local M.tuberculosis strains have a fewer number of copies compared to data shown in most countries. (who.int)
  • Drug resistant M. tuberculosis strains were examined by RFLP typing to determine whether a significant association between specific RFLP types and drug resistance is present. (who.int)
  • The emergence of MdR-TB and extensively drug-resistant TB (XdR-TB) has raised special concerns in relation to the international spread of par- ticularly dangerous strains of Mycobacterium tuberculosis . (bvsalud.org)
  • However, the study said, "The evolution of pathogenic bacterial species from nonpathogenic ancestors is … marked by relatively small changes in the overall gene content. (sciencedaily.com)
  • An interdisciplinary team of researchers led by Dr Ioannis Nezis from the School of Life Sciences, University of Warwick, and Dr Tamas Korscmaros from Earlham Institute and Quadram Institute, Norwich, UK screened the proteome from 56 pathogenic bacterial species - to see how autophagy reacts with them. (plcontracts.com)
  • The following is a review of an opportunistic pathogen of primary concern-Mycobacterium avium complex (MAC). (wcponline.com)
  • ABSTRACT This study aimed to determine the occurrence of Mycobacterium avium complex and other nontuberculous mycobacteria in drinking-water in Basra governorate, Iraq and their susceptibility to several antibiotics and the effect of 0.5 mg/L of chlorine on their survival. (who.int)
  • Bacillus subtilis sRNAs Bacterial small RNA Brucella sRNA Bacteroides thetaiotaomicron sRNA Caenorhabditis elegans sRNA Escherichia coli sRNA Pseudomonaa sRNA Arnvig KB, Young DB (August 2009). (wikipedia.org)
  • These ferredoxin systems are important in controlling electron transfer across bacterial secondary metabolite production processes which include antibiotic and pigment formation among others. (rsc.org)
  • Many other bacterial species have developed antibiotic resistances. (mdpi.com)
  • Background: Mixed infections ofMycobacterium tuberculosis and antibiotic heteroresistance continue to complicate tuberculosis (TB) diagnosis and treatment. (9lib.org)
  • In most cases, if you have a bacterial infection, your doctor will prescribe an antibiotic medication to treat and cure the infection. (umiamihealth.org)
  • Emerging bacterial antimicrobial (antibiotic) resistance (AMR) is a global threat to human health. (who.int)
  • In conclution, DNA amplification is a rapid, reliable and accurate method with a high degree of sensitivity and specificity for the detection of Mycobacterium tuberculosis DNA sequences and it can replace the conventional culture method in the diagnosis of extra pulmonary tuberculosis and tuberculosis meningitis except in the situation when antibiotic sensitivity results are required. (who.int)
  • Bacterial species devoid of ubiquinone, such as Staphylococcus aureus and Mycobacterium tuberculosis , can efficiently respire aerobically using naphthoquinone. (ucsd.edu)
  • In the Middle Ages, a new clinical form of tuberculosis was described as scrofula, which is a disease of cervical lymph nodes. (news-medical.net)
  • At the completion of this learning activity, participants should be familiar with the clinical presentations, epidemiologies, diagnoses, therapies, and preventions of bacterial tropical diseases. (unboundmedicine.com)
  • The laboratory also offers direct microscopic examination and culture of clinical specimens for primary identification of Mycobacterium species in cases referred by local health departments or the TB control program, (317) 233-7434. (in.gov)
  • Knowledge of bacterial antimicrobial susceptibility testing (AST) patterns is the cornerstone of an effective clinical and public health response to AMR. (who.int)
  • The objective of the study was to develop a rapid method to detect Mycobacterium tuberculosis from clinical samples and the applicability of DNA amplification techniques to a developing country like Sri Lanka. (who.int)
  • In this study 465 clinical samples were tested using PCR and the results obtained indicates that this approach offers may advantages over conventional methods and could be used to detect Mycobacterium tuberculosis in clinical samples. (who.int)
  • Bacterial, fungal, and viral infections may involve the pericardium (pericarditis), although viral pericarditis is more common than bacterial pericarditis in both children and adults. (medscape.com)
  • Here, we discuss the latest developments using zebrafish models of bacterial and fungal infection. (frontiersin.org)
  • We create personalized treatment plans based on the cause of your infection and your health to prevent and fight bacterial, fungal, and viral infections. (umiamihealth.org)
  • 2 The use of the polymerase chain reaction (PCR) in identifying bacterial species using unique sequences of 16s ribosomal DNA have been successful in confirming the identity of E. rhusiopathiae . (vin.com)
  • Nucleoid-associated proteins (NAPs) regulate multiple cellular processes such as gene expression, virulence, and dormancy throughout bacterial species. (bvsalud.org)
  • The proteins responsible for controlling electron transfer in bacterial secondary metabolism are not always known or characterised. (rsc.org)
  • Discovering the function of unknown proteins is difficult, particularly for species-specific proteins, for which sequence-based methods of annotation fail. (seattlechildrens.org)
  • We hypothesized that Clp is required for the physiologic turnover of mycobacterial proteins whose accumulation is deleterious to bacterial growth and survival. (cornell.edu)
  • They found that host cells use autophagy to target specific bacterial proteins for recycling. (plcontracts.com)
  • The genomes of MAC species are large, containing thousands of genes involved in various cellular processes and adaptations to different environments. (medicalnewstoday.com)
  • All archaeal and many bacterial genomes contain Clustered Regularly Interspaced Short Palindrome Repeats (CRISPR) and variable arrays of the CRISPR-associated ( cas ) genes that have been previously implicated in a novel form of DNA repair on the basis of comparative analysis of their protein product sequences. (biomedcentral.com)
  • The functioning of this system seems to involve integration of fragments of foreign genes into archaeal and bacterial chromosomes yielding heritable immunity to the respective agents. (biomedcentral.com)
  • His main research interests concern the identification of genes and enzymes involved in this pathway, the regulation of this metabolism, the mode of action of antibiotics and bacteriocins interfering with this pathway and the corresponding resistance mechanisms, as well as the molecular bases for the recognition of bacterial cell-wall peptidoglycan by host innate immunity mechanisms. (degruyter.com)
  • 3] In fact a quick BLAST search of Propionibacterium acnes genes for 16S ribosomal RNA (GenBank: AB097215.1) against M. tuberculosis shows an 88% identity within the first 100 hits. (j-alz.com)
  • He also identified that M. tuberculosis can infect the gastrointestinal tract, bones, joints, nervous systems, lymph nodes, genital and urinary tracts, and skin (extra-pulmonary tuberculosis), in addition to the respiratory tract (pulmonary tuberculosis). (news-medical.net)
  • Based on this study PCR was found to be more sensitive than culture or microscopy in those with a final diagnosis of extra pulmonary tuberculosis. (who.int)
  • The MAC is a group of closely related mycobacterial species that share similar characteristics and cause similar infections. (medicalnewstoday.com)
  • Autophagy is a well-conserved lysosomal degradation pathway that plays key roles in bacterial infections. (frontiersin.org)
  • A number of bacterial species in the broad category of Gram-negative rods can cause human infections, which range in severity and site of the body affected. (livestrong.com)
  • Bacterial infections are common in tropical parts of the world and can include those species also seen regularly in temperate climates. (unboundmedicine.com)
  • quiz 578-80 JF - Journal of the American Academy of Dermatology JO - J Am Acad Dermatol VL - 54 IS - 4 N2 - UNLABELLED: Bacterial infections are common in tropical parts of the world and can include those species also seen regularly in temperate climates. (unboundmedicine.com)
  • With drug resistance being on the rise worldwide, bacterial infections pose one of the greatest global threats to human health. (plcontracts.com)
  • In this first-time audit of deaths published in The Lancet, bacterial infections were found to be the second most important cause of death after ischemic heart disease. (emedinexus.com)
  • Prevention of infection, rational use of antibiotics, improved microbiological testing and vaccination are few approaches to tackle this high burden of bacterial infections and prevent mortality. (emedinexus.com)
  • Mutagenesis of cysQ (Rv2131c) was initially unsuccessful, but was possible when a porin-like gene of Mycobacterium smegmatis was expressed, and also by gene switching in the merodiploid strain. (biomedcentral.com)
  • PI-containing molecules have been demonstrated as essential for growth in the fast-growing species Mycobacterium smegmatis , as mutants lacking PI synthase are not viable [ 8 ]. (biomedcentral.com)
  • Our study identified a novel mechanism maintaining Bacillus subtilis and Mycobacterium smegmatis biofilms-active production of calcite minerals. (nature.com)
  • Furthermore, we show that calcite-dependent morphogenesis is a conserved phenomenon, occurring in an additional genetically distant soil bacterium, Mycobacterium smegmatis . (nature.com)
  • Only pure viable cultures of clinically significant bacterial isolates are accepted. (in.gov)
  • In this study, researchers assessed the infection-related deaths that occurred in 2019 in 204 countries in 11 infectious diseases caused by 33 clinically significant bacterial species. (emedinexus.com)
  • State law requires laboratories to submit isolates of Mycobacterium tuberculosis to the Mycobacteriology laboratory for confirmation and susceptibility testing. (in.gov)
  • A total of 252 isolates were identi- ria such as M. abscessus , M. mucogenicum , using the monophasic-biphasic culture fied as Mycobacterium spp. (who.int)
  • However, several studies test-tube represents a biphasic environ- M. simiae (comprising 25.8% of total have failed to identify nontuberculous ment (a liquid phase in contact with isolates), scotochromogens, identified mycobacteria in water samples, often be- solid one), while the upper portion is as M. szulgai (7.5% of total isolates) and cause of unsuitable isolation techniques single phase (solid only). (who.int)
  • Typing of Mycobacterium tuberculosis isolates is of great potential value for basic and epidemiological studies on tuberculosis. (who.int)
  • The pathophysiology of erythema multiforme (EM) is still not completely understood, but it is probably immunologically mediated and appears to involve a hypersensitivity reaction that can be triggered by a variety of stimuli, particularly bacterial, viral, or chemical products. (medscape.com)
  • A high index of suspicion for bacterial tracheitis is needed in children with viral croup-like symptoms who do not respond to standard croup treatment or clinically worsen. (medscape.com)
  • Hospitalized croup (bacterial and viral): the role of rigid endoscopy. (medscape.com)
  • Transport media are usually not used for throat culture, which is principally performed for bacterial isolation, but are essential for the handling of specimens to identify viral antigens and immunoglobulins. (medscape.com)
  • MTB and MAC are diseases caused by mycobacteria but differ in several ways. (medicalnewstoday.com)
  • Dr. Jacobs adds that findings from this study could also enhance treatment of diseases caused by other species of mycobacteria. (rdworldonline.com)
  • Diabetes weakens the immune system and makes individuals more prone to infectious diseases such as, tuberculosis. (who.int)
  • 1. Dunn J. Bacterial and mycotic diseases of cetaceans and pinnipeds. (vin.com)
  • Some tropical bacterial diseases, eg, plague and anthrax, are associated with high mortality rates and are of potential use in bioterrorism. (unboundmedicine.com)
  • Some tropical bacterial diseases are closely associated with specific activities such as hunting (ie, tularemia) or eating raw seafood (Vibrio vulnificus infection). (unboundmedicine.com)
  • The bacterial diseases having the most severe medical impact in the tropics are those caused by members of the Mycobacterium genus. (unboundmedicine.com)
  • Because of the increasing frequency of travel to tropical parts of the world for tourism and work as well as the increasing number of immigrants and adoptees from these areas, it is imperative that physicians practicing in temperate climates be able to recognize the signs and symptoms of tropical bacterial diseases, carry out the proper diagnostic tests, and initiate appropriate therapy and prevention. (unboundmedicine.com)
  • TY - JOUR T1 - Tropical dermatology: bacterial tropical diseases. (unboundmedicine.com)
  • Tuberculosis (TB) - one of the oldest diseases in the world - continues to devastate the lives of millions per year. (9lib.org)
  • The links in this section will take you to a list of other diseases for that same category (e.g. diseases affecting that species, in a specific region, etc. (iastate.edu)
  • Mycobacterial diseases other than those caused by M. tuberculosis complex should not be counted in tuberculosis morbidity statistics unless there is concurrent tuberculosis. (cdc.gov)
  • DMT adjuvanted WH121 vaccinated C57BL/6 mice could confer persistent and significant protection against the respiratory challenge with 80 CFU of virulent M. tuberculosis H37Rv at 9 and 18 weeks after immunization, as the BCG vaccine did. (oncotarget.com)
  • Belonging to the same genus, Mycobacteria, they also share some features. (medicalnewstoday.com)
  • It is believed that the genus Mycobacterium was present in the environment about 150 million years ago, and an early variant of M. tuberculosis was originated in East Africa about 3 million years ago. (news-medical.net)
  • M. tuberculosis causes TB and is a highly contagious respiratory infection, primarily affecting the lungs. (medicalnewstoday.com)
  • San Diego, Calif., Nov. 25, 2019 -- A new study provides a fundamental understanding of the diversification of small molecules called respiratory quinones and its adaptive consequences in bacterial species. (ucsd.edu)
  • However, a large number of bacterial species still respire aerobically using the ancient respiratory quinone, naphthoquinone. (ucsd.edu)
  • To examine metabolic limitations of aerobic naphthoquinone usage in bacterial species with the ability to produce both types of respiratory quinones, researchers engineered a ubiquinone-deficient strain of E. coli to force it to respire aerobically using the ancient respiratory quinone. (ucsd.edu)
  • AND 3) Positive growth of bacterial pathogen(s) identified from respiratory specimen(s) taken on or after day 3 of ventilation. (who.int)
  • This distinction is important as it reflects differences in the bacterial wall, which influences its susceptibility to different antibiotics. (livestrong.com)
  • This study confirms the high susceptibility of HIV-infected individuals to infection with different Cryptosporidium species and subtypes, and further stresses the importance of surveillance for opportunistic intestinal protozoans. (biomedcentral.com)
  • Drug susceptibility testing will be repeated if the patient is still culture positive for M. tuberculosis after 3 months of therapy. (in.gov)
  • Susceptibility testing for other Mycobacterial species is not performed. (in.gov)
  • This presents the problem of whether candidates such as cell-wall-deficient filamentous forms of a microbe like those of M. tuberculosis would or could through existing known sequences even be considered. (j-alz.com)
  • Due to various factors including socioeconomic factors, compliance is poor to anti-tuberculosis drugs, leading to resistance. (preprints.org)
  • We aim to determine the prevalence of Multidrug resistance (MDR) tuberculosis in Pakistani population. (preprints.org)
  • Conclusion Multi-drug resistance tuberculosis is very prevalent in Pakistan, which may increase burden on health care system and may lead to various complications of tuberculosis. (preprints.org)
  • I am looking for a straight-forward way to compare metabolic pathways (presence and absence enzymes) in several annotated but not yet published bacterial genomes, it should be non-commercial and can be command-line based. (biostars.org)
  • M. tuberculosis has a unique cell wall structure composed of mycolic acids, contributing to its potential to become resistant to certain antibiotics . (medicalnewstoday.com)
  • Hélène Barreteau is assistant professor at the University Paris-Sud, Orsay, and a member of the Laboratory of Bacterial Envelopes and Antibiotics. (degruyter.com)
  • She joined the Laboratory of Bacterial Envelopes and Antibiotics as an engineer in 2007. (degruyter.com)
  • He is director of research at CNRS and, since 2001, is the head of the Laboratory of Bacterial Envelopes and Antibiotics which, for more than 30 years, has been studying the biochemistry, genetics and physiology of the bacterial cell-wall peptidoglycan biosynthesis pathway as a whole. (degruyter.com)
  • Didier Blanot is director of research at CNRS and a member of the Laboratory of Bacterial Envelopes and Antibiotics, University Paris-Sud, Orsay. (degruyter.com)
  • Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak. (cdc.gov)
  • In 1720, a British physician, Benjamin Marten, first described the infectious origin of tuberculosis in his publication entitled 'A new theory of Consumption. (news-medical.net)
  • The most highly infectious patients are those who develop cavitatory lung disease [ 1 ], since each cavity may contain up to 10 9 mycobacteria [ 5 ], and these patients can be regarded as the aerosol supershedders that drive the global pandemic. (ersjournals.com)
  • The team is adapting and refining methodologies established in the Institute for Health Metrics and Evaluation (IHME)'s ongoing Global Burden of Disease (GBD) study to build an evidence base of bacterial AMR across the globe, with corresponding visualisations. (ox.ac.uk)
  • While this study used cultured cells, it is hypothesized that the PCR may be sensitive enough to allow detection of bacterial directly from slime coat samples further reducing the time needed for detection. (vin.com)
  • We evaluated the feasibility of an early prototype ligand-coated magnetic bead technology to concentrate M. tuberculosis prior to detection by LED-based fluorescence microscopy compared with direct Ziehl-Neelsen microscopy and direct and concentrated fluorescence microscopy in a reference laboratory in Kampala, Uganda. (biomedcentral.com)
  • A recent study reported encouraging performance of ligand-coated magnetic beads in combination with FM, in detection of M. tuberculosis in a panel of frozen sputum samples, with good correlation reported between magnetic bead concentration and centrifugation [ 7 ]. (biomedcentral.com)
  • Neisseria meningitidis, or meningococcus, is a leading cause of bacterial meningitis -- a life-threatening infection of membranes brain and spinal cord, which can spread throughout the body via the bloodstream. (livestrong.com)
  • In 1843, Philipp Friedrich Hermann Klencke, a German physician, experimentally produced the human and bovine forms of tuberculosis for the first time by inoculating extracts from a miliary tubercle into the liver and lungs. (news-medical.net)
  • Bovine tuberculosis is a chronic, bacterial disease of cattle that occasionally affects other species of mammals. (iastate.edu)
  • A Greek physician, Clarissimus Galen, who became the physician of the Roman Emperor Marcus Aurelius in 174 AD, described the symptoms of tuberculosis as fever, sweating, coughing and blood-stained sputum. (news-medical.net)
  • Symptoms of bacterial tracheitis may be intermediately between those of epiglottitis and croup. (medscape.com)
  • Recent reports suggest it is a leading cause of bacterial tracheitis and associated with increased intubation. (medscape.com)
  • Pam Barrett Scanlon, LBSW, CPM, Tuberculosis Controller, Alabama Department of Public Health, spoke about experiences with a "Tuberculosis Outbreak in Perry County, Alabama, and the Implementation of Interventions to Contain. (cdc.gov)
  • In a separate session on Genomic Epidemiology, Ben Silk, PhD, Lead of the Molecular Epidemiology Activity Team, DTBE, presented, "Data Integration and Visualization for Tuberculosis Outbreak Investigations. (cdc.gov)
  • Through PFGE, a unique bacterial DNA fingerprint is obtained, analyzed, and submitted to the PulseNet National Database at the Centers for Disease Control to track for local and national outbreak patterns. (in.gov)
  • The synthesis of the peptide stem of bacterial peptidoglycan involves four enzymes, the Mur ligases (MurC, D, E and F). Among them, MurD is responsible for the ATP-dependent addition of d -glutamic acid to UDP-MurNAc- l -Ala, a reaction which involves acyl-phosphate and tetrahedral intermediates. (degruyter.com)
  • Approximately one-third of the world's population is thought to be infected with the causative organism, Mycobacterium tuberculosis (Mtb) [ 3 ]. (ersjournals.com)
  • In Sri Lanka definitive diagnosis of tuberculosis depends on the culture of mycobacteria, but the slow growth of the organism delays the diagnosis. (who.int)
  • 3 The protocol was then repeated using intact bacterial cells from broth culture and from plated colonies of the same isolate of E. rhusiopathiae . (vin.com)
  • PCR products of the anticipated size were amplified using genomic DNA, dilutions of bacterial broth cultures and plated colonies as template. (vin.com)
  • Use of a quantitative TaqMan-PCR for the fast quantification of mycobacteria in broth culture, eukaryotic cell culture and tissue. (vin.com)
  • Filtered samples were incubated for 7 days or less in a monophasic-biphasic culture setup of tuberculosis broth and Lowenstein-Jensen agar. (who.int)
  • In 2007, approximately 1.7 million deaths were caused by tuberculosis (TB) and an estimated 9.3 million people acquired the infection [ 1 ]. (biomedcentral.com)
  • Occurrence studies of mycobacteria in water have found variable results. (wcponline.com)
  • Nucleic acid amplification (NAA) tests must be accompanied by culture for mycobacteria species. (cdc.gov)
  • These species commonly exist in the water and soil. (medicalnewstoday.com)
  • a hypersensitivity reaction to Aspergillus species that occurs most commonly in people with asthma, but sometimes in patients with CF, can cause or contribute to bronchiectasis. (msdmanuals.com)