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  • etiology
  • Purpose Timely knowledge of the bacterial etiology and localization of infection are important for empirical antibiotic therapy. (lu.se)
  • article{fc527924-b535-486a-a1ed-82b56234d51a, abstract = {Purpose Timely knowledge of the bacterial etiology and localization of infection are important for empirical antibiotic therapy. (lu.se)
  • However, they can be useful in establishing the etiology of the infection only in specific cases (e.g. procalcitonin in sepsis), but generally they are not sensitive and specific enough to make an unambiguous decision [1- (termedia.pl)
  • On the other hand, tests which are known as a gold standard for confirmation of bacterial or viral etiology of infection (microbiological culture or polymerase chain reaction - PCR, respectively) are laborious and, what is more important, time-consuming. (termedia.pl)
  • acute infection
  • We performed double-blind, multicenter assay evaluation using serum remnants collected at 5 pediatric emergency departments and 2 wards from children ≥3 months to ≤18 years without ( n = 68) and with ( n = 529) suspicion of acute infection. (aappublications.org)
  • Of 529 potentially eligible patients with suspected acute infection, 100 did not fulfill infectious inclusion criteria and 68 had insufficient serum. (aappublications.org)
  • The discriminatory power of HNL concentrations in serum was seen in additional studies on children and adults, indicating that HNL measurements in serum might be a clinically useful biomarker for the distinction between bacterial or viral causes of acute infection ( 9 , 10 ). (asm.org)
  • immune system
  • Nonetheless, a child who is around other children will inevitably be exposed to infections, which will over time help strengthen their immune system. (robbreport.com)
  • Specifically, in findings published in the Nov. 14 issue of Science , the researchers described that activation of the innate immune system with the bacterial protein flagellin could prevent and cure rotavirus infection, which is amongst the most common causes of severe diarrhea. (psu.edu)
  • Generally viral infections are controlled by immune system molecules called interferons, which interfere with viral replication, or by specific antibodies from preimmunized conditions which neutralize the virus," Vijay-Kumar said. (psu.edu)
  • Such unnecessary antibiotic treatment can cause severe side effects like toxicity, allergic reactions, suppression of immune system, intestinal bacterial flora disruption or even, according to the latest studies, obesity. (termedia.pl)
  • Gene expression in the blood changes when the immune system is fighting off a bacterial or viral infection. (wired.co.uk)
  • When infected by a virus, a person's immune system responds differently than when fighting a bacterial infection. (medindia.net)
  • differentiation
  • A novel assay that integrates measurements of blood-borne host-proteins (tumor necrosis factor-related apoptosis-inducing ligand, interferon γ-induced protein-10, and C-reactive protein [CRP]) was developed to assist in differentiation between bacterial and viral disease. (aappublications.org)
  • Conclusions From the novel potential biomarkers, only PCT demonstrated superiority over the routine parameters in the differentiation of bacterial from viral infections. (lu.se)
  • discriminate
  • But Storch and his colleagues at the universitys Genome Institute and the Genome Technology Access Center wanted to know whether a test called a gene expression microarray could identify patterns of gene activity in white blood cells that could discriminate children with viral infections from those with bacterial infections. (infectioncontroltoday.com)
  • intestinal
  • Matam Vijay-Kumar's colleagues in the Department of Nutritional Sciences are thrilled with his research accomplishments focused on the preventing intestinal viral infections by harnessing host innate immunity via exploiting bacterial product," said Gordon Jensen, professor and head of nutritional sciences at Penn State. (psu.edu)
  • humans
  • At a side event of the 66th WHA entitled 'Antibiotic Resistance - a threat to Global Health Security and a Case for Action' 12 countries outlined their strategies to address the problem, strategies that essentially involve: severely reducing antibiotic use in the humans and animals, preventing drug-resistant microbial infections and researching new pharmaceutical products. (homeopathy-ecch.org)
  • area under
  • Results The highest sensitivity and specificity (expressed as the area under the curve [AUC]) for bacterial infection were observed in serum concentration of PCT (0.952), neutrophil and lymphocyte counts (0.852 and 0.841, respectively), and serumlevels of HBP (0.837), IL-6 (0.830), and Cort (0.817). (lu.se)
  • clinical
  • The distinction between causes of acute infections is a major clinical challenge. (asm.org)
  • Finally, it should be remembered that the whole clinical situation should be taken into consideration, and that blood counts and their characteristcs are only an aid, as the kinetics of the PMN in response to infections are extremely complex. (nus.edu.sg)
  • The team gathered clinical data, took blood from each patient, and conducted a battery of microbiologic tests to determine which individuals had a bacterial infection (41 patients) and which had a non-bacterial or viral infection (53 patients). (eurekalert.org)
  • Childhood Infections
  • While more work is needed, the studys results support the notion that analyzing the activity of the bodys genes in response to childhood infections could help to identify the cause of illness and ensure that children get the right treatment. (infectioncontroltoday.com)
  • organisms
  • The organisms causing infection may originate from the victim's own resident flora, either on the skin or on adjacent mucous membranes, but many come from other people, animals, or the environment. (doctorlib.info)
  • infants
  • Dr. Ramilo and a team of more than 50 physicians across the United States are investigating the use of novel technologies for distinguishing between bacterial and viral infections in infants with fevers within emergency departments. (bio-medicine.org)
  • In fact, 6 to 10 percent of these infants arrive with serious, bacterial infections. (bio-medicine.org)
  • We plan to determine the host response to infection using RNA biosignatures that could help address some very challenging problems when evaluating these young, vulnerable infants," said Dr. Ramilo, also a faculty member at The Ohio State University College of Medicine. (bio-medicine.org)
  • In a cohort of 2945 infants, 61.6% underwent viral testing, with 48.1% (n=1200) of participants demonstrating a positive test result. (clinicaladvisor.com)
  • illness
  • Common viral infections in children usually last only a short time and are best treated by insuring adequate fluid intake, the restriction of strenuous exercise and allowing the illness to run its course. (robbreport.com)
  • Most virus infections cause a short illness of 3-5 days and then go away on their own. (healthtap.com)
  • In instances such as pandemic flu or the corona-virus that has erupted in the Middle East, it's extremely important to diagnose a viral illness far more accurately and speedier than can be done using traditional diagnostics," said co-senior author Geoffrey S. Ginsburg, M.D., Ph.D., director of Genomic Medicine and professor of medicine at Duke University School of Medicine. (medindia.net)