Bacterial nucleoid proteins. Medical search. Frequent questions

We propose that the presence of a compact, incompletely replicated nucleoid or unsegregated chromosome masses at the normal mid-cell division site inhibits Z-ring formation and that the SOS system, SlmA, and MinC are not required for this inhibition. (nih.gov)
Timely assembly of polar Z rings and precise capture of the chromosome in the forespore both require the DNA-binding protein RefZ. (tamu.edu)
We propose that RBM-bound RefZ complexes function as a developmentally regulated nucleoid occlusion system for fine-tuning the position of the septum relative to the chromosome during sporulation.IMPORTANCE The bacterial nucleoid forms a large, highly organized structure. (tamu.edu)
During B. subtilis sporulation, the nucleoid undergoes reorganization, and the cell division protein FtsZ assembles polarly to direct septation over one chromosome. (tamu.edu)
Our data suggest that RefZ exploits nucleoid organization by associating with polarly localized RBMs to modulate the positioning of FtsZ relative to the chromosome during sporulation. (tamu.edu)
popZ proteins anchors the chromosome at its parS sequence (near oriC ) to the old pole, which is mediated by parB. (hideyuki-ts.com)
The bacterial chromosome is compacted in a manner optimal for DNA transactions to occur. (ucm.es)
The single, circular DNA chromosome of bacteria is not enclosed in a nucleus, but instead occupies a specific location, the nucleoid, within the cell. (opentextbooks.org.hk)
The packing proteins of bacteria are, however, related to some of the proteins involved in the chromosome compaction of eukaryotes. (opentextbooks.org.hk)
The single, circular chromosome exists in a region of cytoplasm called the nucleoid. (opentextbooks.org.hk)
A prokaryotic chromosome is oblique and lives within the nucleoid. (differencey.com)
The Escherichia coli chromosome or nucleoid consists of the genomic DNA, RNA, and protein. (mygentaur.com)
4) The DNA inside the chromosome appears to have a condition-dependent 3-D development that is linked to gene expression so that the nucleoid construction and gene transcription are tightly interdependent, influencing each other reciprocally. (mygentaur.com)
The bacterial DNA is very much simple and is contained totally equipped within a single circular molecule, called the bacterial chromosome. (onlyzoology.com)
In fact, these are irregularly shaped nucleus-like primitive holding of the genetic materials that include one or two circular chromosomes (mostly a single circular chromosome) that are made up of DNA, RNA, histones, and other cellular proteins. (onlyzoology.com)
13. Viruses have (AIPMT 2014) (a) DNA enclosed in a protein coat (b) prokaryotic nucleus (c) single chromosome (d) both DNA and RNA. (recruitmenttopper.com)
Finally, we confirm that the observed nucleoid size stems from a balance between the forces that the chromosome and mRNAs exert on each other. (princeton.edu)
In Escherichia coli and related bacteria, we believe that both plasmids and the bacterial chromosome use site-specific recombination to convert multimers to monomers. (gla.ac.uk)
It is shown that the only DNA sequences required for wild-type dif function in the terminus region of the chromosome are contained within 33 bp known to bind XerC and XerD, and that certain active site residues of the Xer proteins known to be involved in the catalysis of recombination are required for normal chromosome segregation. (gla.ac.uk)

The Golgi body receives proteins, synthesized by ribosomes on the rough endoplasmic reticulum, via transport vesicles. (visiblebody.com)
Ribosomes are made mostly of rRNA (ribosomal ribonucleic acid), and bacterial cells contain more than 50 associated proteins, whereas plant and animal cells contain 80 associated proteins. (visiblebody.com)
The primary function of ribosomes is protein synthesis. (visiblebody.com)
Proteins synthesized by ribosomes are used by organelles in the cell, by the plasma membrane, or by structures outside the cell. (visiblebody.com)
Rough ER is continuous with the outer nuclear membrane, and it has numerous, protein-synthesizing ribosomes attached to it. (visiblebody.com)
Ribosomes deposit proteins into the lumen of the rough ER, where they can be modified. (visiblebody.com)
Additionally, bacteria also have other structures such as ribosomes for protein synthesis, a cell wall for protection, and in some cases, flagella for movement. (goodsiteslike.com)
They use the host's nucleotides to replicate their genetic material and the host's ribosomes to synthesize their proteins. (goodsiteslike.com)
No such protective membrane can be seen around the single circular loop of DNA in the bacterial cell, and also that the single circular loop of DNA is not separated at all from the other cellular components of the bacterial prokaryotic cells like cytoplasm, plasmids, mitochondria, chloroplasts, ribosomes, etc. (onlyzoology.com)
In bacteria such as Escherichia coli, DNA is compacted into a nucleoid near the cell center, whereas ribosomes-molecular complexes that translate mRNAs into proteins-are mainly localized to the poles. (princeton.edu)
In addition, our analysis reveals a "circulation" of ribosomes driven by the flux of mRNAs, from synthesis in the nucleoid to degradation at the poles. (princeton.edu)

Z-ring inhibition occurred independently of SOS, SlmA-mediated nucleoid occlusion, and MinCDE proteins and did not result from a decreased FtsZ protein concentration. (nih.gov)
The TetR family protein RefZ binds DNA motifs (RBMs) localized near the poles at the time of division and is required for both timely FtsZ assembly and precise capture of DNA in the future spore compartment. (tamu.edu)
This essay introduces FtsZ as a highly conserved protein involved in septum formation and its regulation in model organsisms, and gives examples on diviations from these rules that mainly comes from studies on nonmodel organisms. (hideyuki-ts.com)
Central to almost all bactrial division is the FtsZ protein. (hideyuki-ts.com)
The FtsZ ring then recruits other proteins of the divisome, allowing division to proceed. (hideyuki-ts.com)
However, the FtsZ protein that plays such a vital role in prokaryotic cytokinesis is structurally and functionally very similar to tubulin, the building block of the microtubules that make up the mitotic spindle fibers that are necessary for eukaryotes. (opentextbooks.org.hk)
The formation of a ring composed of repeating units of a protein called FtsZ directs the partition between the nucleoids in prokaryotes. (opentextbooks.org.hk)
Formation of the FtsZ ring triggers the accumulation of other proteins that work together to recruit new membrane and cell-wall materials to the site. (opentextbooks.org.hk)
FtsZ proteins can form filaments, rings, and other three-dimensional structures resembling the way tubulin forms microtubules, centrioles, and various cytoskeleton components. (opentextbooks.org.hk)
In this example, FtsZ is presumed to be similar to the ancestor protein to both the modern FtsZ and tubulin. (opentextbooks.org.hk)
While both proteins are found in extant organisms, tubulin function has evolved and diversified tremendously since the evolution from its FtsZ-like prokaryotic origin. (opentextbooks.org.hk)
The FtsZ protein active in prokaryote cell division is very similar to tubulin in the structures it can form and its energy source. (opentextbooks.org.hk)
FtsZ proteins assemble into a ring that pinches the cell in two. (opentextbooks.org.hk)
Unlike some other partition mutants, FtsZ ring formation was inhibited in such cells and the first division of nucleoids following induction resulted in their accumulation transverse to the cell's length rather than longitudinally in the usual way. (ucl.ac.uk)

Examples include the HU protein in Escherichia coli, a dimer of closely related alpha and beta chains and in other bacteria can be a dimer of identical chains. (wikipedia.org)
HU-type proteins have been found in a variety of bacteria (including cyanobacteria) and archaea, and are also encoded in the chloroplast genome of some algae. (wikipedia.org)
Histone-like proteins were unknown to be present in bacteria until similarities between eukaryotic histones and the HU-protein were noted, particularly because of the abundancy, basicity, and small size of both of the proteins. (wikipedia.org)
Upon further investigation, it was discovered that the amino acid composition of HU resembles that of eukaryotic histones, thus prompting further research into the exact function of bacterial DNA binding proteins and discoveries of other related proteins in bacteria. (wikipedia.org)
Currently, many more functions of bacteria DNA binding proteins have been discovered, including the regulation of gene expression by histone-like nucleoid-structuring protein, H-NS. (wikipedia.org)
H-NS is about 15.6 kDa and assists in the regulation of bacterial transcription in bacteria by repressing and activating certain genes. (wikipedia.org)
Because of the speed of bacterial cell division, populations of bacteria can grow very rapidly. (opentextbooks.org.hk)
Do Bacteria have Nucleus or Nucleoid? (onlyzoology.com)
Unlike the true nucleus of eukaryotic cells, the prokaryotic cells of bacteria have a nucleoid that is not membrane-bound. (onlyzoology.com)
This central portion contains all or most of the genetic materials that bacteria need in order to synthesize proteins and survive. (onlyzoology.com)
But, if you want to see the nucleoid part of the bacteria with the single circular DNA loop, then you will definitely need an electron micrograph at a high magnification between 1 and 50 million times depending on which type you use and how precise you want to see. (onlyzoology.com)
Yes, bacteria have nucleoids but no nucleus because they are prokaryotic cells. (onlyzoology.com)
So, this very clearly indicates that nucleoid is present in bacteria, and not the nucleus. (onlyzoology.com)
What is a Nucleoid in bacteria? (onlyzoology.com)
Nucleoids in bacteria or in other prokaryotes like Archaea are not true-nucleus. (onlyzoology.com)
Nucleoid in bacteria is very poorly organized, irregularly shaped, very small, lacks a protective membrane to hold the genetic materials inside. (onlyzoology.com)

They are commonly referred to as histone-like and have many similar traits with the eukaryotic histone proteins. (wikipedia.org)
Eukaryotic histones package DNA to help it to fit in the nucleus, and they are known to be the most conserved proteins in nature. (wikipedia.org)
In these high salt concentrations, the eukaryotic histone protein is eluted from a DNA solution in which single stranded DNA is bound covalently to cellulose. (wikipedia.org)
HU is a small (10 kDa) bacterial DNA-binding protein, which structurally differs from a eukaryotic histone but functionally acts similarly to a histone by inducing negative supercoiling into circular DNA with the assistance of topoisomerase. (wikipedia.org)
in eukaryotic cells the most important of these proteins are the histones . (wikipedia.org)
To our knowledge, p11.6 is the first bacterial histone-like DNA-binding protein found in an animal virus or eukaryotic cell system. (illinois.edu)
The types of proteins present on prokaryotic chromosomes, typically known as nucleoid-related proteins, They vary from the histone proteins found on eukaryotic chromosomes and form prokaryotic chromosomes. (differencey.com)
The chromosomal DNA is present in cells in a extraordinarily condensed, organized sort known as nucleoid (nucleus-like), which is not encased by a nuclear membrane as in eukaryotic cells. (mygentaur.com)
Bacterial cells are those ancestor cells from where the present-day eukaryotic cells have evolved over the course of millions of years of evolution. (onlyzoology.com)

We investigate the mobility of proteins in the bacterial cytoplasm and cytoplasmic membrane as well as membrane model systems, using optical microscopy-based techniques such as fluorescence correlation spectroscopy (FCS) and pulsed-FRAP (panel a). (rug.nl)

ParABS partition systems, comprising the centromere-like DNA sequence parS, the parS -binding ParB-CTPase and the nucleoid-binding ParA-ATPase, ensure faithful segregation of bacterial chromosomes and low-copy-number plasmids. (biorxiv.org)

The role of single-stranded DNA binding (SSB) protein during DNA replication in Escherichia coli cells has been studied, specifically the interactions between SSB and the χ subunit of DNA polymerase III in environments of varying salt concentrations. (wikipedia.org)
Here, using cryo soft X-ray tomography imaging of native unlabeled cells and using a semi-automatic analysis and segmentation procedure, we show that Hfq significantly remodels the Escherichia coli nucleoid. (cea.fr)
The modes of bacterial cell division vary, but the most common one is binary fission (Stahl 2019) , and its mechanism, especially in rod-shaped model organisms Escherichia coli and Bacillus subtilis , has been studied extensively. (hideyuki-ts.com)

As shown in Figure 3.1 , this is typically achieved using two mechanisms, nucleoid occlusion (NO), and the Min system, which are well characterised in E. coli and B. subtilis . (hideyuki-ts.com)
Nuclear occlusion prevents Z-ring formation atop of nucleoids. (hideyuki-ts.com)

Kocer, A., Walko, M., and Feringa, B.L. (2007) Synthesis and utilization of reversible and irreversible light-activated nanovalves derived from the channel protein MscL. (rug.nl)
Protein synthesis is crucial for cell growth and survival yet one of the most energy-consuming cellular processes. (yale.edu)
How, then, do cells sustain protein synthesis under starvation conditions when energy is limited? (yale.edu)
EF-G2's singular ability to sustain protein synthesis, albeit at slow rates, is crucial for bacterial gut colonization. (yale.edu)
Moreover, we uncover a 26-residue region unique to EF-G2 that is essential for protein synthesis, EF-G2 dissociation from the ribosome, and responsible for the absence of GTPase activity. (yale.edu)
Our findings reveal how cells curb energy consumption while maintaining protein synthesis to advance fitness in nutrient-fluctuating environments. (yale.edu)
catalyzes the synthesis (creation) of proteins are composed of two subunits that come together to form a functi-oning structure. (cheatography.com)

When replication elongation was blocked by hydroxyurea or nalidixic acid, arrested cells contained one partially replicated, compact nucleoid located mid-cell. (nih.gov)
Crenarchaeal genomes are organized into a compact nucleoid by a set of small chromatin proteins. (silverchair.com)

In prokaryotes, only two proteins are required to begin replication, although eukaryotes benefit from constructs made up of completely different protein subunits. (differencey.com)

Despite its small genome and limited number of effector proteins, Ehrlichia efficiently establishes an intracellular infection and avoids immune defenses in vertebrate and invertebrate hosts through complex molecular and cellular reprogramming strategies. (frontiersin.org)
Transcriptomic studies on the human pathogen Streptococcus pneumoniae, which has a relatively small genome (∼2 Mb) and few nucleoid-binding proteins, have been performed under conditions of local and global changes in supercoiling. (ucm.es)
This approach will allow comparison of nucleoid proteins, and any modifications thereof, associated with transcriptionally active and inactive regions of the bacterial genome. (uea.ac.uk)
2017. Nucleoid-Associated Proteins: Genome Level Occupancy and Expression Analysis. . (ncbs.res.in)
Although genome-wide mRNA-nucleoid segregation still lacks experimental validation, our model predicts that ∼90%of mRNAs are segregated to the poles. (princeton.edu)

Our results indicate that Hfq could regulate nucleoid compaction directly via its interaction with DNA, but also at the post-transcriptional level via its interaction with RNAs. (cea.fr)
The degree of compaction results from the level of DNA-supercoiling and the presence of nucleoid-binding proteins. (ucm.es)
This suggests a potential global feedback circuit in which gene expression feeds back on itself via nucleoid compaction. (princeton.edu)

In molecular biology, bacterial DNA binding proteins are a family of small, usually basic proteins of about 90 residues that bind DNA and are known as histone-like proteins. (wikipedia.org)
These dinoflagellate histone-like proteins replace histone in some dinoflagellates and package DNA into a liquid-crystalline state. (wikipedia.org)
Histone-like proteins are present in many Eubacteria, Cyanobacteria, and Archaebacteria. (wikipedia.org)
Here we describe an African swine fever virus (ASFV) protein encoded by the open reading frame 5-AR that shares structural and functional similarities with the family of bacterial histone-like proteins which include histone-like DNA binding proteins, integration host factor, and Bacillus phage SPO1 transcription factor, TF1. (illinois.edu)
The histone-like nucleoid structuring protein (H-NS) functions as a transcriptional silencer by binding to AT-rich sequences at bacterial promoters. (healthcarecoremeasures.com)
The forming of biofilm neighborhoods is crucial for survival and persistence in character as well such as disease transmitting [5 9 The histone-like nucleoid structuring proteins (H-NS) is certainly a nucleoid linked DAPK Substrate Peptide proteins and transcriptional repressor [12]. (healthcarecoremeasures.com)

Instead, they are essentially nucleic acid (DNA or RNA) enclosed in a protein coat called a capsid. (goodsiteslike.com)
E. coli is a most popular host for the look at of phage biology due to the detailed knowledge of its nucleic acid and protein biosynthetic pathways. (mygentaur.com)
c) They have ability to synthesize nucleic acids and proteins. (recruitmenttopper.com)

Regulation of gene expression by proteins and small RNAs. (otago.ac.nz)
The involvement of viral DNA-binding proteins in the regulation of virulence genes, transcription, DNA replication, and repair make them significant targets. (mdpi.com)
The identified inversions had more overlap than expected with nucleoid-associated protein binding sites, which assist in the regulation of genomic gene expression . (bvsalud.org)
3 The tandem CBS domain 4 , which is linked to the nucleotide binding protein, plays a pivotal role in the regulation. (rug.nl)
Although there is little knowledge of chromatin structure in Archaea, similarities between crenarchaeal and bacterial chromatin proteins suggest that organization and regulation could be achieved by similar mechanisms. (silverchair.com)
In the present review, we describe the molecular properties of crenarchaeal chromatin proteins and discuss the possible role of these architectural proteins in organizing the crenarchaeal chromatin and in gene regulation. (silverchair.com)
In this review, regulation of V. vulnificus VVP, VVH and VvsA is clarified in terms of expression at the mRNA and protein levels. (elsevierpure.com)
cAMP is generated by adenylate cyclase CyaA, and in complex with cAMP receptor protein (CRP), this nucleotide has been shown to upregulate HapR production through the positive regulation of the CAI-I synthase CqsA and the negative regulation of Fis. (kegg.jp)

in these processes, bacterial DNA binding proteins have an architectural role, maintaining structural integrity as transcription, recombination, replication, or any other DNA-dependent process proceeds. (wikipedia.org)
In DNA replication at the lagging strand site, DNA polymerase III removes nucleotides individually from the DNA binding protein. (wikipedia.org)
Twinkle ( T7 gp4-like protein with intramitochondrial nucleoid localization, also known as C10orf2, PEO1, SCA8, ATXN8, IOSCA, PEOA3 or SANDO) is a homohexameric DNA helicases which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. (nih.gov)
2022. Replication-dependent organisation constrains positioning of long DNA repeats in bacterial genomes. . (ncbs.res.in)
Growing evidence is suggesting that specific proteins and sub-cellular components(e.g. the nucleoid) need to be highly organized both on the membrane and inside the cellularvolume in order to carry out vital tasks like cell replication or chemotaxis and to respond toexternal changes in the environment. (amolf.nl)

a plastid-encoded bacterial-type RNA polymerase (PEP) and a nuclear-encoded phage-type RNA polymerase (NEP), which recognize distinct types of promoters. (frontiersin.org)
We show here that PLASTID REDOX INSENSITIVE 2 (PRIN2) and CHLOROPLAST STEM-LOOP BINDING PROTEIN 41 kDa (CSP41b), two proteins identified in plastid nucleoid preparations, are essential for proper plant embryo development. (frontiersin.org)

The three proteins MinCDE form an oscillation cycle from pole to pole (driven by MinDE), causing the time-averaged concentration of MinCD complexes to be lowest at the midcell, which favours Z-ring formation there. (hideyuki-ts.com)

The bacterial nucleoid and its influence on gene expression. (otago.ac.nz)
alter gene expression and are associated with nucleoid protein binding sites. (bvsalud.org)
The co-occurrence analysis of core concepts in this stringent response, i.e. the (p)ppGpp nucleotides with gene products was also inspected and suggest that besides the enzymes RelA and SpoT that control the basal levels of (p)ppGpp nucleotides, many other proteins have a key role in this response. (biomedcentral.com)

Taken together, our findings reveal a new role for this protein in nucleoid remodeling in vivo, that may serve in response to stress conditions and in adapting to changing environments. (cea.fr)

In fact, they have a nucleoid which is a thin and transparent area within the bacteria's prokaryotic cell, that contains loops of circular DNA. (onlyzoology.com)
This nucleoid is an irregularly shaped region within the central portion of the prokaryotic cell. (onlyzoology.com)

The bacterial chromosomic DNA is packed within a membrane-less structure, the nucleoid, due to the association of DNA with proteins called Nucleoid Associated Proteins (NAPs). (cea.fr)
We have proposed that under conditions of severe osmotic stress (panel b, lower figure), the cell membrane contacts the nucleoid, which creates pools of proteins and hinders free diffusion through the cell. (rug.nl)
A bacterial genomic DNA resides inside cells in a extraordinarily condensed and functionally organized sort known as nucleoid (nucleus-like development with out a nuclear membrane). (mygentaur.com)
In fact, they have an irregularly shaped nucleoid that contains their genetic materials within no definite membrane-bound boundary. (onlyzoology.com)
Over-expression of ycf 24 in E. coli using the pMAL-c2 vector resulted in moderate filamentation, the fusion protein localizing as a band on either side of the nucleoid, sometimes extending along the membrane to the cell poles. (ucl.ac.uk)

The integration host factor (IHF), a dimer of closely related chains which is suggested to function in genetic recombination as well as in translational and transcriptional control is found in Enterobacteria and viral proteins including the African swine fever virus protein A104R (or LMW5-AR). (wikipedia.org)
This group also contains viral GP4-like and related bacterial helicases. (nih.gov)
Understanding these differences is not only crucial for academic purposes but also plays a significant role in the development of effective strategies for combating bacterial and viral infections. (goodsiteslike.com)
This fundamental difference in metabolism is one reason why antibiotics, which target bacterial metabolic processes, are ineffective against viral infections. (goodsiteslike.com)

E. coli is a most popular host for protein manufacturing as a consequence of its quick progress and the facility to particular proteins at very extreme ranges. (mygentaur.com)
The flexibleness of E. coli to develop on chemically outlined media coupled with its intensive genetic toolbox make it a key system in look at of bacterial metabolic pathways. (mygentaur.com)

Figure 7.1 (a) Nasal sinus cells (viewed with a light microscope), (b) onion cells (viewed with a light microscope), and (c) Vibrio tasmaniensis bacterial cells (seen through a scanning electron microscope) are from very different organisms, yet all share certain characteristics of basic cell structure. (infolearners.com)
The cyclic AMP receptor protein modulates colonial morphology in Vibrio cholerae. (kegg.jp)
The small nucleoid protein Fis is involved in Vibrio cholerae quorum sensing. (kegg.jp)

The possible roles of molecular hydrogen, a common by-product of bacterial fermentation, are also addressed. (techscience.com)
Current advents of high-resolution microscopy, single-molecule analysis and molecular development willpower of the elements are anticipated to reveal the complete development and efficiency of the bacterial nucleoid. (mygentaur.com)

Microtubules are polymers of the protein tubulin. (opentextbooks.org.hk)

In this thesis I investigated experimentally the spatialorganization of different sub-cellular components (nucleoid) and protein species (NAPs andchemoreceptors) and its importance for physiological processes inside living bacterial cells.Most of the experiments presented here are carried out in living cells, and our results thusprovide insights also into the spatio-temporal organization and the dynamics of the responseto controlled perturbations. (amolf.nl)

A DNA-Binding Protein Tunes Septum Placement during Bacillus subtilis Sporulation. (tamu.edu)
A septum is formed between the nucleoids from the periphery toward the center of the cell. (opentextbooks.org.hk)

Thus, in addition to storing the genetic code, the nucleoid harbors positional information that can be leveraged by DNA-binding proteins to spatially constrain cellular activities. (tamu.edu)
This nucleoid can in no way be compared with a nucleus because it is that central region of the bacterial cell that stores all the genetic material and controls cellular activities within a no boundary region. (onlyzoology.com)

Genomic reorganization, such as rearrangements and inversions, influences how genetic information is organized within the bacterial genomes . (bvsalud.org)
Type I toxin-antitoxin (TA) systems are widespread genetic modules in bacterial genomes. (mdpi.com)

F-plasmid partition complexes containing ParB F and parS F move by generating and following a local concentration gradient of nucleoid-bound ParA F . However, the process through which ParB F activates ParA F -ATPase has not been defined. (biorxiv.org)
It is a bacterial and infectious intervened transduction, plasmid intervened conjugation and frequent change. (differencey.com)

In this review, we assess the potential role of putative gut microbiota products in the etiopathogeny of Parkinson's disease, with a special emphasis on functional bacterial amyloid proteins, bacterial biosurfactants, endotoxins and short-chain fatty acids. (techscience.com)

The PEP enzyme recognizes the -10 and -35 cis -elements, similar to those found in bacterial promoters whereas the NEP enzyme recognizes the YRTA-motif, which can also be found upstream of several genes with PEP promoters indicating that these genes can be transcribed by both polymerases ( Pfannschmidt and Liere, 2005 ). (frontiersin.org)

Bacterial conjugation will be utilized to change large DNA fragments from one bacterium to a distinct. (mygentaur.com)

These proteins, aided by chaperone proteins , bind to and condense the DNA molecule to maintain its integrity. (wikipedia.org)
As in eukaryotes, the DNA of the nucleoid is associated with proteins that aid in packaging the molecule into a compact size. (opentextbooks.org.hk)

Although studies suggest that αSyn and its missense mutant, A53T, preferentially accumulate in the mitochondria, the mechanisms by which αSyn and mitochondrial proteins regulate each other to trigger mitochondrial and neuronal toxicity are poorly understood. (springer.com)

We have shown that, in the open state MscL, forms pores with a diameter of 3 nm 1 , which allows passage of small proteins. (rug.nl)

the protein is involved in stabilizing the lagging strand as well as interacting with DNA polymerase III. (wikipedia.org)

Overexpression of the enhanced intracellular survival (Eis) protein by Mtb confers resistance to the second-line antibiotic kanamycin (KAN). Eis is an acetyltransferase that acetylates KAN, inactivating its antimicrobial function. (cdc.gov)
Mechanisms by which E. chaffeensis establishes intracellular infection, and avoids host defenses are not well understood, but involve functionally relevant host-pathogen interactions associated with tandem and ankyrin repeat effector proteins. (frontiersin.org)
One of the ABC transporters that is studied in detail is the osmoregulatory ABC transporter OpuA (class D). Osmotic control of OpuA involves gating by intracellular ionic strength and is mediated by lipid-protein interactions. (rug.nl)

Here, we show that the protein level of ClpP is selectively decreased in αSyn-expressing cell culture and neurons derived from iPS cells of PD patient carrying αSyn A53T mutant, and in dopaminergic (DA) neurons of αSyn A53T mice and PD patient postmortem brains. (springer.com)
This envelope often contains proteins that are crucial for the virus to infect host cells. (goodsiteslike.com)
Strains mutant in dif, xerC, or xerD, share a characteristic phenotype, containing a variable fraction of filamentous cells with aberrantly positioned and sized nucleoids. (gla.ac.uk)

The nucleoid varieties by condensation and purposeful affiliation of a single chromosomal DNA with the help of chromosomal architectural proteins and RNA molecules along with DNA supercoiling. (mygentaur.com)

They form one of the largest known protein families and are found in organisms from all kingdoms of life. (rug.nl)
Instead, the bacterial DNA is found in a region of the cell called the nucleoid. (goodsiteslike.com)
But, nucleoplasm and nucleolus can in no way be found in the nucleoid. (onlyzoology.com)

The MinC, MinD and MinE proteins interact to prevent Z-ring formation at the poles (Ghosal et al. (hideyuki-ts.com)

To accelerate the translocation of mRNA-tRNAs through the ribosome, bacterial elongation factor G (EF-G) hydrolyzes energy-rich guanosine triphosphate (GTP) for every amino acid incorporated into a protein. (yale.edu)

Anatomy12

Organisms12

Chemicals and Drugs45

Analytical, Diagnostic and Therapeutic Techniques and Equipment15

Phenomena and Processes40

Disciplines and Occupations2

Information Science3

Health Care2

Chromosome19

Ribosomes11

FtsZ14

Bacteria16

Eukaryotic9

Cytoplasm1

Chromosomes1

Escherichia3

Occlusion2

Synthesis7

Compact nucleoid2

Prokaryotes1

Genome5

Compaction3

Histone6

Nucleic3

Regulation8

Replication5

Plastid2

MinCDE1

Gene3

Vivo1

Prokaryotic2

Membrane5

Viral4

Coli2

Vibrio3

Molecular2

Tubulin1

NAPs1

Septum2

Cellular2

Genetic2

Plasmid2

Functional1

Promoters1

Conjugation1

Molecule2

Regulate1

Small1

Polymerase1

Intracellular3

Cells3

Architectural1

Found3

Poles1

Amino1