• 4. Verification of isochromosome 12p and identification of other chromosome 12 aberrations in gonadal and extragonadal human germ cell tumors by bicolor double fluorescence in situ hybridization. (nih.gov)
  • Preliminary results on a broad series of compounds belonging to different biological classes (herbicide, insecticide, fungicide) seem to indicate that pesticides are toxic but are poor initiating agents, as shown by negative or weak positive results on different genetic end points (gene mutations, DNA effects, and chromosome aberrations in vitro and in vivo). (nih.gov)
  • Chromosomal aberrations in lymphocytes were evaluated by fluorescence in situ hybridization with painting probes for chromosomes 1, 2, 3, and 4 in spring and autumn. (bvsalud.org)
  • An increase in the frequency of unstable chromosome aberrations, that is, dicentric chromosomes and acentric fragments, was observed in spring samples from Ostrava (p = .014 and p = .044, respectively) and Prague (p = .002 and p = .006, respectively) in comparison with Ceske Budejovice. (bvsalud.org)
  • Our study showed, that air pollution increased the frequency of unstable chromosome aberrations, especially dicentric chromosomes. (bvsalud.org)
  • The introduction of FISH (fluorescence in situ hybridization) marked the beginning of a new era for the study of chromosome structure and function. (biosyn.com)
  • 5. Identification of multiple chromosome 12 abnormalities in human testicular germ cell tumors by two-color fluorescence in situ hybridization (FISH). (nih.gov)
  • 7. Fluorescence in situ hybridization of 12p in germ cell tumors using a bacterial artificial chromosome clone 12p probe on paraffin-embedded tissue: clinical test validation. (nih.gov)
  • 9. Fluorescence in situ hybridization analysis of chromosome 12p in paraffin-embedded tissue is useful for establishing germ cell origin of metastatic tumors. (nih.gov)
  • 11. Interphase fluorescence in situ hybridization analysis of chromosome 12p abnormalities is useful for distinguishing epidermoid cysts of the testis from pure mature teratoma. (nih.gov)
  • 14. Overrepresentation of chromosome 12p sequences and karyotypic evolution in i(12p)-negative testicular germ-cell tumors revealed by fluorescence in situ hybridization. (nih.gov)
  • 16. Triple-color FISH analysis of 12p amplification in testicular germ-cell tumors using 12p band-specific painting probes. (nih.gov)
  • More breakpoints were observed on chromosome 1 than on the other chromosomes examined (p (bvsalud.org)
  • The number of breakpoints in the heterochromatin region 1p11-q12 was lower than in other parts of chromosome 1 (p (bvsalud.org)
  • In order to check the types and extent of evolutionary conserved breakpoints we studied here for the first time the chromosomes of Hylobates pileatus (HPI) compared to HSA and Hylobates lar (HLA) by means of molecular cytogenetics. (biomedcentral.com)
  • In this study, we compared chromosome damage in city policemen from three cities in the Czech Republic: industrial Ostrava characterized by high levels of benzo[a]pyrene, Prague with heavy traffic emitting nitrogen oxides, and relatively clean Ceske Budejovice located in an area with predominantly agricultural activity. (bvsalud.org)
  • This study provides full karyotypic data and previously not available data on heterochromatin-syntenies of HPI and HSA. (biomedcentral.com)
  • The diploid chromosome number of M. simplicicornis argentina topotype corresponded with the karyotypical pattern of S. gouazoubira with 2n = 70 and FN = 70, showing a great similarity in all classic and molecular cytogenetic results and revealing the homologies between karyotypes. (bvsalud.org)
  • Later in 1909, with the help of the microscopy technology at the time, Theodor Boveri coined the termed chromosome territories after observing that chromosomes occupy individually distinct nuclear regions. (wikipedia.org)
  • Moreover, entire chromosomes segregate into distinct regions called chromosome territories. (wikipedia.org)
  • The organization of chromosomes into distinct regions within the nucleus was first proposed in 1885 by Carl Rabl. (wikipedia.org)
  • Additionally, high-throughput sequencing technologies such as Chromosome Conformation Capture-based methods can measure how often DNA regions are in close proximity. (wikipedia.org)
  • Understanding genomes of other species and comparing them to HSA needs full karyotypic and high resolution genomic data to approach both: euchromatic and heterochromatic regions of the studied chromosome-content. (biomedcentral.com)