• To assess clinician experience with transfusion-associated bacterial infections and knowledge of the new AABB standard, the Infectious Diseases Society of America (ISDA) conducted a survey of infectious-disease consultants in the United States. (cdc.gov)
  • Infectious Diseases Society of America Emerging Infections Network, Alexandria, Virginia. (cdc.gov)
  • This report summarizes two fatal cases of transfusion-associated sepsis in platelet recipients in 2004 and describes results of a 2004 survey of infectious-disease consultants regarding their knowledge of transfusion-associated bacterial infections and the new AABB standard. (cdc.gov)
  • However, health-care providers also should be able to diagnose transfusion-associated infections, because even when testing complies with the new standard, false negatives can occur and fatal bacterial sepsis can result. (cdc.gov)
  • The survey was distributed via e-mail and fax during July 27--August 24, 2004, to all 870 infectious-disease consultant members of the Emerging Infections Network, a sentinel provider network of ISDA ( 4 ). (cdc.gov)
  • Bacterial infections. (medlineplus.gov)
  • Superficial bacterial skin infections and cellulitis. (medlineplus.gov)
  • Although previously considered a mere nuisance infection, untreated bacterial vaginosis may cause increased susceptibility to sexually transmitted infections, including HIV, and pregnancy complications. (wikipedia.org)
  • BV is a risk factor for pelvic inflammatory disease, HIV, sexually transmitted infections (STIs), endometriosis, and reproductive and obstetric disorders or negative outcomes. (wikipedia.org)
  • The main limitations of this study were the exclusion of certain infectious diseases due to data availability issues, not considering the impact of co-infections and co-morbidity, and the inability to assess the burden of milder infections that do not result in healthcare utilization. (nih.gov)
  • Our investigators study all aspects of infectious disease ranging from the fundamental science of microbial pathogens to the clinical outcomes of the infections they cause. (imperial.ac.uk)
  • The scientists were also able to show in mice that these bacteria help the bacterial composition inside the intestines regenerate more quickly after antibiotic therapy and ensure that protection against infections is restored. (eurekalert.org)
  • About 90% of those infected result in latent infections, and about 10% of latent infections develop active diseases when their immune system is impaired due to the age, other diseases such as AIDS or exposure to immunosuppressive drugs. (genome.jp)
  • Autophagy is a well-conserved lysosomal degradation pathway that plays key roles in bacterial infections. (frontiersin.org)
  • Here, we review the many functions of autophagy in bacterial infections with a focus on macrophages, the first line of host defenses, and the replicative niche of numerous pathogens. (frontiersin.org)
  • July 20, 2017 - The Foundation for the NIH (FNIH) Biomarkers Consortium (BC) has met a critical milestone that could improve clinical trials and accelerate treatment approvals for hospital-acquired bacterial infections. (fnih.org)
  • In particular, the FDA recently updated guidance based on the BC's recommendations for endpoints in clinical trials of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI). (fnih.org)
  • PHAXIAM is a biopharmaceutical company developing innovative treatments for resistant bacterial infections, which are responsible for many serious infections. (krqe.com)
  • Over the last decade, research on antimicrobials has shifted towards an alternative approach to combat pathogens using anti-infective drugs that selectively interrupt virulence pathways to help prevent or cure bacterial infections. (nature.com)
  • A particulate matter: How environmental irritants and particulate matter increase sensitivity to bacterial respiratory tract infections. (lu.se)
  • Vaccine-preventable disease control is continually strengthening in NSW with notable successes in invasive bacterial infections. (who.int)
  • Bacterial vaginosis (BV) is an infection of the vagina caused by excessive growth of bacteria. (wikipedia.org)
  • So far, three cases of infection from the bacteria Burkholderia pseudomallei have been reported to the U.S. Centers for Disease Control and Prevention. (infectiousdiseaseadvisor.com)
  • As many risk factors for the disease are associated with advanced medical care, a direct relationship between the availability of these technologies and the frequency of this infection is likely. (medscape.com)
  • Does This Patient With Acute Infectious Conjunctivitis Have a Bacterial Infection? (jamanetwork.com)
  • 4 Section of Infectious Diseases and Center for Prostheses Infection, Baylor College of Medicine, Houston, Texas. (nih.gov)
  • Project SummaryImmune defense against bacterial infection requires activation of conserved signaling pathways that upregulateproduction of inflammatory mediators to clear infection. (usda.gov)
  • How CARD19-induced cell death is coupled to inflammatoryresponses and host defense against bacterial infection is not known. (usda.gov)
  • Chronic active Epstein-Barr virus (EBV) infection is a severe systemic disease associated with high rates of mortality and morbidity. (researchgate.net)
  • Infectious mononucleosis owing to primary Epstein-Barr virus (EBV) infection sometimes causes hepatitis, which is usually self-limiting with mildly elevated transaminases, but can rarely develop into severe hepatitis with jaundice. (researchgate.net)
  • However, EBV has been linked to several refractory diseases such as EBV-associated hemophagocytic syndrome(EBV-AHS) and chronic active EBV infection (CAEBV). (researchgate.net)
  • Brucellosis is a zoonotic bacterial infection. (medicinenet.com)
  • Brucellosis is a zoonotic infection (meaning the disease occurs mainly in animals but is occasionally transferred to humans). (medicinenet.com)
  • Viral and Bacterial Adhesion Network Training (ViBrANT) places adhesion at the heart of virulence: it plays the first and decisive role in the infection process of pathogens. (europa.eu)
  • Pediatric bacterial meningitis is a life-threatening illness that results from bacterial infection of the meninges and leaves some survivors with significant sequelae. (medscape.com)
  • This report describes case notification data for measles, pertussis, rubella, Haemophilus influenzae type b invasive infection, invasive meningococcal disease (IMD), mumps, tetanus and invasive pneumococcal disease (IPD) in NSW, Australia, in 2012 and provides comparison with recent trends. (who.int)
  • The Broad Institute's Genomic Center for Infectious Diseases (GCID) was established in 2014 by the National Institute of Allergy and Infectious Diseases (NIAID) to to apply innovative genomic technologies to address fundamental gaps in our knowledge of the basic biology that underlies the interactions between hosts and pathogens. (broadinstitute.org)
  • A major focus is the evolution and spread of bacterial pathogens (and antibiotic resistance) including the interactions that these pathogens have with their host and host-associated microbiota. (broadinstitute.org)
  • Some tests (eg, Gram stain, routine aerobic culture) can detect a large variety of pathogens and are commonly done for many suspected infectious illnesses. (msdmanuals.com)
  • Marked sex-specific differences in disease burden were observed for some pathogens. (nih.gov)
  • But which bacterial species are 'good', or 'commensal' in technical terms, and how can they protect against colonisation, i.e. how can they prevent pathogens from settling? (eurekalert.org)
  • Finally, we discuss the opportunities and challenges of autophagy manipulation in improving therapeutics and vaccines against bacterial pathogens. (frontiersin.org)
  • Infectious diseases, particularly drug resistant pathogens, are a key global health issue. (europa.eu)
  • Anti-infective drugs that do not perturb survival or viability of bacterial pathogens should be less likely to promote resistance than conventional antibiotics 1 , 2 . (nature.com)
  • Organism-specific therapeutic regimens for bacterial meningitis are outlined below, including those for Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, Listeria monocytogenes, Streptococcus agalactiae, Enterobacteriaceae organisms, and Pseudomonas aeruginosa . (medscape.com)
  • Beside high mortality, acute bacterial meningitis may lead to a high frequency of neuropsychological sequelae. (biomedcentral.com)
  • The aim of this study was to estimate the frequency of neuropsychological sequelae after acute bacterial meningitis in four of the eight regions of Niger. (biomedcentral.com)
  • Subjects exposed to acute bacterial meningitis were enrolled into a cohort with non exposed subjects matched on age and gender. (biomedcentral.com)
  • The comparison of the frequency of sequelae between non exposed and exposed subjects to bacterial meningitis was also calculated using the Fisher exact test. (biomedcentral.com)
  • This study carried out in Niger confirms two serious neurological sequelae occurring at high frequencies after bacterial meningitis: severe and profound hearing loss and motor impairment. (biomedcentral.com)
  • In the perspective of physical rehabilitation, the most serious sequelae after acute bacterial meningitis are neurological including motor impairment, epilepsy, cecity or vision loss, speech disorder and hearing loss. (biomedcentral.com)
  • In Africa, studies of bacterial meningitis sequelae have been mainly conducted more within hospital wards than in peripheral and remote health care centres usually located far from reference hospitals. (biomedcentral.com)
  • In a retrospective study of children with bacterial meningitis complicated by stroke, treatment with heparin or aspirin appeared to be safe and to discourage stroke recurrence, with heparin possibly being the more effective of the two medications. (medscape.com)
  • See Clinical Presentation for more specific information on the signs and symptoms of pediatric bacterial meningitis. (medscape.com)
  • See Workup for more specific information on testing and imaging modalities for pediatric bacterial meningitis. (medscape.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • Several thousand cases of encephalitis are reported to the Centers for Disease Control and Prevention (CDC) every year. (kidshealth.org)
  • I received the Centers for Disease Control and Prevention Immunization Champion Award for the state of Ohio in 2018. (cincinnatichildrens.org)
  • According to the U.S. Centers for Disease Control and Prevention (CDC), brucellosis is only weakly contagious because person-to-person spread of brucellosis is rare. (medicinenet.com)
  • You'll also have the opportunity to use our specialist facilities, including computational methods to analyse large biological datasets to answer the 'big' questions in microbiology, from bacterial epidemiology to evolution. (bath.ac.uk)
  • We aim to describe the epidemiology of selected vaccine-preventable diseases in New South Wales (NSW) for 2012. (who.int)
  • Before transfusion, the pooled platelet unit had been tested for bacterial contamination with a reagent strip test (Multistix ® , Bayer Diagnostics, Tarrytown, New York) to determine the pH level, a means for detecting the presence of bacteria. (cdc.gov)
  • The mission of the Bacterial Genomics Group at Broad is to develop and implement 'omics methodologies to answer pressing questions related to bacteria and their role in human health. (broadinstitute.org)
  • When germ-free mice were colonised with different groups of bacteria (12 bacterial strains in total), three additional strains cooperated with K. oxytoca for the protective effect. (eurekalert.org)
  • Under normal conditions, the immune system reacts to the presence of a viral or bacterial illness by producing a variety of immune cells designed to attack the invading viruses or bacteria. (encyclopedia.com)
  • Brucellosis is in infectious disease caused by bacteria in the genus Brucella . (medicinenet.com)
  • Unfortunately, people can easily get the disease from eating or drinking unpasteurized or raw dairy products and can even become infected by inhaling aerosolized bacteria or become infected through breaks in the skin or mucous membranes. (medicinenet.com)
  • In addition, the bacteria have been documented to survive in the environment for up to two years under favorable conditions (darkness, cold temperatures, and relatively high CO2 concentrations) and still cause disease. (medicinenet.com)
  • Kuhn C, Disque C, Muhl H, Orszag P, Stiesch M, Haverich A. Evaluation of commercial universal rRNA gene PCR plus sequencing tests for identification of bacteria and fungi associated with infectious endocarditis. (medscape.com)
  • To develop the recommendations, the BC convened a project team that includes experts from the National Institute of Allergy and Infectious Diseases (NIAID), the FDA, not-for-profit organizations and pharmaceutical companies. (fnih.org)
  • Evans, TD & Zhang, F 2020, ' Bacterial metabolic heterogeneity: origins and applications in engineering and infectious disease ', Current Opinion in Biotechnology , vol. 64, pp. 183-189. (wustl.edu)
  • Dr Teresa Thurston, Advanced Research Fellow in the Department of Infectious Disease, discusses her journey to obtaining a Fellowship. (imperial.ac.uk)
  • UKRI Future Leaders Fellow Vanessa Sancho-Shimizu talks about the challenges and highlights of her Fellowship journey so far, and what she enjoys about working in the Department of Infectious Disease. (imperial.ac.uk)
  • 6 Department of Infectious Disease, Cleveland Clinic, Ohio. (nih.gov)
  • Evidence-based tools to aid the clinical diagnosis of viral vs bacterial conjunctivitis are lacking and may contribute to overprescribing of topical antibiotics. (jamanetwork.com)
  • We examined the relationship between serum Bb fragment concentration at IgAN diagnosis with disease activity and outcomes. (bvsalud.org)
  • Patients have been reported to present with symptoms and signs of bacterial tracheitis and multiorgan failure due to exotoxin-producing strains of Staphylococcus aureus or Streptococcus pyogenes in the trachea. (medscape.com)
  • A synthetic cocktail of 12 bacterial strains colonises germ-free mice stably over several generations and forms an intestinal microbiota representative of mice. (eurekalert.org)
  • Any drug impairing crucial processes for bacterial life will inevitably lead to the development of drug-resistant strains, whereas the inhibition of biofilm formation might prevent the onset of bacterial resistance. (intechopen.com)
  • The CVI988 strain of Marek's disease virus (MDV) is a highly effective vaccine to protect chicken against very virulent strains of MDV. (thepoultrysite.com)
  • Shanika Kurukulasuriya of the Western College of Veterinary Medicine at the University of Saskatchewan in Canada explained recent studies have demonstrated that the majority of Infectious Bursal Disease Viruses (IBDVs) circulating in Canada are 'variant' strains and capable of immunosuppression in broilers. (thepoultrysite.com)
  • also, this was to help only Before and skip a view an atlas of the clinical microbiology of infectious diseases volume 1 on the Employees. (testblog.eu)
  • Notably, the most prominent bacterial phyla are Bacteroides, Firmicutes, Proteobacteria, and Actinobacteria , and the Prevotella, Veillonella, but Streptococcus and Pseudomonas were also commonly isolated bacterial genera in the respiratory samples of TB patients and controls. (springer.com)
  • The remaining 106 respiratory samples represented all specimens submitted for investigation of bacterial pneumonia during a one-week period in August 1999, at the Department of Clinical Microbiology, Herlev University Hospital. (biomedcentral.com)
  • We search been to Using slides by According our view an atlas of the clinical microbiology of infectious and material to articulate our stakeholders. (testblog.eu)
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  • The global Veterinary Infectious Disease Diagnostics Market boasts a total value of $1.7 billion in 2021 and is projected to register a growth rate of 9.0% to reach a value of $2.6 billion by 2026. (marketsandmarkets.com)
  • The increasing pet population is expected to drive the demand for pet care products and services, which, in turn, will support the growth of dependent industries such as veterinary infectious disease diagnostics. (marketsandmarkets.com)
  • ABSTRACT Bacterial vaginosis (BV) is the most prevalent form of vaginal disturbances in women of child- bearing age. (who.int)
  • Bacterial vaginosis (BV) is a change in vag- in the evaluation of asymtomatic women inal ecosystem where the normally domi- because this organism is carried by 30%- nant lactobacilli are greatly reduced and 40% of women who do not have bacterial replaced with a number of other organ- vaginosis [ 8 ]. (who.int)
  • It has been shown that HIV-infected women with bacterial vaginosis (BV) are more likely to transmit HIV to their sexual partners than those without BV. (wikipedia.org)
  • In addition, bacterial vaginosis as either pre-existing, or acquired, may increase the risk of pregnancy complications, most notably premature birth or miscarriage. (wikipedia.org)
  • Fungi cause 0-12% (average 1.1%) of infectious endocarditis cases in children worldwide. (medscape.com)
  • Fungal endocarditis is often difficult to diagnose because the presentation may be nonspecific, and the disease typically occurs in otherwise critically ill patients with confusing clinical pictures. (medscape.com)
  • Candida endocarditis: contemporary cases from the International Collaboration of Infectious Endocarditis Merged Database (ICE-mD). (medscape.com)
  • We used health-adjusted life years (HALYs), a composite measure comprising premature mortality and reduced functioning due to disease, to estimate the burden of 51 infectious diseases and associated syndromes in Ontario using 2005-2007 data. (nih.gov)
  • Finally, we provide a discussion of recent studies examining the importance of metabolic heterogeneity in applied settings such as infectious disease and metabolic engineering. (wustl.edu)
  • Deaths were estimated from vital statistics data and disease incidence was estimated from reportable disease, healthcare utilization, and cancer registry data, supplemented by local modeling studies and national and international epidemiologic studies. (nih.gov)
  • Growth can largely be attributed to the growth in the companion animal population, increasing incidence of transboundary and zoonotic diseases, rising demand for animal-derived food products, rising demand for pet insurance, growing animal health expenditure, and growth in the number of veterinary practitioners and income levels in developed economies. (marketsandmarkets.com)
  • History Bacterial keratitis is a significant ocular infectious disease that may lead to serious visual impairment. (biotech-angels.com)
  • Meaning Among patients presenting with ocular redness and discharge suggestive of infectious conjunctivitis, certain clinical findings may suggest viral vs bacterial conjunctivitis, although no single symptom or sign differentiated the 2 conditions with high certainty. (jamanetwork.com)
  • Importance Acute infectious conjunctivitis is characterized by ocular redness and discharge, and is a common clinical entity. (jamanetwork.com)
  • To investigate the clinical importance of a positive Pneumocystis -PCR among HIV-uninfected patients suspected of bacterial pneumonia, a retrospective matched case-control study was conducted. (biomedcentral.com)
  • The aim of the current study was to evaluate the clinical significance and prevalence of a PCR positive signal in a broad spectrum of clinical samples from HIV-negative patients with suspected bacterial pneumonia by means of an age and sex matched nested case-control study. (biomedcentral.com)
  • Question Which clinical findings differentiate patients with viral conjunctivitis from those with bacterial conjunctivitis? (jamanetwork.com)
  • clinical findings associated with a higher likelihood of bacterial conjunctivitis included mucopurulent discharge and otitis media. (jamanetwork.com)
  • The Department of Infectious Disease's mission is to apply excellent science and develop new approaches to address the unmet clinical needs for the control of infectious disease, both here in the UK and internationally. (imperial.ac.uk)
  • As an infectious disease physician and director of Adult Clinical Services, I treat each patient as I would want to be treated. (cincinnatichildrens.org)
  • [8] Biofilms can form on the teeth of most animals as dental plaque , where they may cause tooth decay and gum disease . (wikipedia.org)
  • Respiratory samples from 367 patients suspected of bacterial pneumonia were analysed by PCR amplification of Pneumocystis jiroveci . (biomedcentral.com)
  • Upon request from the U.S. Food and Drug Administration (FDA), the FNIH submitted recommendations to the FDA to guide drug development for hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP). (fnih.org)
  • Genomic technologies are providing infectious disease researchers an unprecedented capability to study at a genetic level the viruses that cause disease and their interactions with infected hosts. (broadinstitute.org)
  • Viruses and other germs transmitted by insects, like West Nile virus (spread through a mosquito bite) and the germs that cause Lyme disease and Rocky Mountain spotted fever (spread through tick bites). (kidshealth.org)
  • The company is building on an innovative approach based on the use of phages, natural bacterial-killing viruses. (krqe.com)
  • The goals of the Broad Viral Genomics Group are to pioneer the application of these technologies to address the crucial unanswered biological questions in viral disease, and to foster a community of research leaders focused on using genomics to advance preventative and therapeutic strategies for viral diseases. (broadinstitute.org)
  • 20%-60% in patients visiting services of naecology Clinic of Bahonar Hospital, Ker- sexually transmitted diseases [ 3 ]. (who.int)
  • These guidelines are intended for use by infectious disease specialists, orthopedic surgeons, neurosurgeons, radiologists, and other healthcare professionals who care for patients with native vertebral osteomyelitis (NVO). (nih.gov)
  • Symptoms of bacterial tracheitis may be intermediately between those of epiglottitis and croup. (medscape.com)
  • A high index of suspicion for bacterial tracheitis is needed in children with viral croup-like symptoms who do not respond to standard croup treatment or clinically worsen. (medscape.com)
  • Objective To determine the relative prevalence of viral vs bacterial conjunctivitis in adults and children, and to determine which symptoms or signs are suggestive of a viral vs bacterial etiology. (jamanetwork.com)
  • The Parasite and Vector Genomics group applies genomic and transcriptomic sequencing data to profile variation among individuals and divergence among species to understand the basic biology underlying vector-borne disease transmission, with a focus on malaria. (broadinstitute.org)
  • The most pathogenic (likely to cause disease) species are B. melitensis and B. suis . (medicinenet.com)
  • This course provides you with a broad understanding of the molecular basis of biological systems, with a focus on microbes and their role in disease, developing new medicines, improving food biosecurity and environmental sustainability. (bath.ac.uk)
  • The objectives of vaccine-preventable disease surveillance in NSW are, at an individual level, to identify events that may require immediate public health control measures and, at a population level, to identify risk factors such as age and geographic location that inform better targeted immunization efforts. (who.int)
  • Mostly in subtropical and tropical climates," Julia Petras, an epidemic intelligence service officer with the CDC National Center for Emerging and Zoonotic Infectious Diseases, told HealthDay . (infectiousdiseaseadvisor.com)
  • and deadly infectious diseases are (re)emerging - the most recent being of course Covid-19. (europa.eu)
  • Findings In this systemic review, the relative prevalence of bacterial conjunctivitis was higher than viral conjunctivitis in children, and the prevalence of viral conjunctivitis was higher than bacterial conjunctivitis in adults, but the underlying prevalence data were limited. (jamanetwork.com)
  • Lewy body (ies) (disease) (G31.8) · multiple sclerosis (G35) · neurosyphilis (A52.1) · niacin deficiency [pellagra] (E52) · polyarteritis nodosa (M30.0) · systemic lupus erythematosus (M32. (who.int)
  • Immunizations are also an important way to protect people from diseases like chickenpox and measles. (kidshealth.org)
  • To reduce this risk, AABB (formerly the American Association of Blood Banks) adopted a new standard on March 1, 2004, that requires member blood banks and transfusion services to implement measures to detect and limit bacterial contamination in all platelet components ( 3 ). (cdc.gov)
  • Before transfusion, platelets from the unit bag were tested for bacterial contamination with liquid culture media (BacT/Alert ® , BioMerieux Inc., Durham, North Carolina) by using 4 mL in a standard aerobic blood culture bottle and were found to be negative after 5 days' incubation. (cdc.gov)
  • A total of 143 (36%) respondents reported they were aware that bacterial contamination of platelets is one of the most common infectious risks of transfusion therapy. (cdc.gov)
  • Viral diseases have an enormous impact on human health worldwide. (broadinstitute.org)
  • Viral Diseases of Invertebrates Other Than Insects. (epa.gov)