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MezlocillinAzlocillinPenicillinsTicarcillinCarbenicillinMicrobial Sensitivity TestsPiperacillinPseudomonas aeruginosaEnterobacteriaceaeTobramycinPenicillinaseMeningitis, ListeriaAmpicillinAminoglycosidesCephalosporinsAnti-Bacterial AgentsBacteriaCefsulodinHalf-LifePenicillin ResistancePseudomonas InfectionsAztreonambeta-Lactams

AmpicillinPiperacillinMethicillinBroad spectrum aCarbenicillinPenicillinsPseudomonasBroad-spectrumCephalosporinsStrainsConcentration

Ampicillin1

• Azlocillin is an acyl ampicillin antibiotic with an extended spectrum of activity and greater in vitro potency than the carboxy penicillins. (wikipedia.org)

Piperacillin2

• Azlocillin is similar to mezlocillin and piperacillin. (wikipedia.org)
• Azlocillin and mezlocillin are no longer on the market, having been replaced in clinical practice by ticarcillin-clavulanate and piperacillin-tazobactam, and are not discussed further. (rwmansiononpeachtree.com)

Methicillin1

• Methicillin "Azlocillin sodium salt Susceptibility and Minimum Inhibitory and Concentration (MIC) Data" (PDF). (wikipedia.org)

Broad spectrum a1

• Azlocillin is considered a broad spectrum antibiotic and can be used against a number of Gram positive and Gram negative bacteria. (wikipedia.org)

Carbenicillin2

• Azlocillin was more active against Pseudomonas than was ticarcillin, carbenicillin, or mezlocillin. (nih.gov)
• Such incompatibilities are critical because they often affect vital drugs such as aminoglycoside antibiotics, which are known to be inactivated by carbenicillin, azlocillin, or mezlocillin [ 23 ] or precipitated by heparin. (medscape.com)

Penicillins2

• The activity of azlocillin and mezlocillin, new semisynthetic ureido penicillins, was investigated and compared with that of other known beta-lactam antibiotics. (nih.gov)
• Azlocillin is an acyl ampicillin antibiotic with an extended spectrum of activity and greater in vitro potency than the carboxy penicillins. (wikipedia.org)

Pseudomonas3

• At a concentration of 25 mug/ml, azlocillin inhibited 74% of Enterobacter, 97% of Proteus mirabilis, 64% of Citrobacter, 91% of Pseudomonas aeruginosa, and 82% of Bacteroides strains tested. (nih.gov)
• Mezlocillin inhibited 86% of Shigella, 96% of Enterobacter, 80% of indole-positive Proteus, 88% of Bacteroides, and 63% of Pseudomonas strains tested. (nih.gov)
• 0.03 μg/mL - 2 μg/mL Pseudomonas aeruginosa 4 μg/mL - 6.25 μg/mL An interesting alternative synthesis of azlocillin involves activation of the substituted phenylglycine analogue 1 with 1,3-dimethyl-2-chloro-1-imidazolinium chloride (2) and then condensation with 6-APA. (wikipedia.org)

Broad-spectrum1

• Azlocillin is considered a broad spectrum antibiotic and can be used against a number of Gram positive and Gram negative bacteria. (wikipedia.org)

Cephalosporins1

• Synergy of azlocillin and mezlocillin combined with aminoglycoside antibiotics and cephalosporins. (nih.gov)

Strains1

• Azlocillin and mezlocillin were less active than cefazolin against beta-lactamase-producing E. coli and Klebsiella strains but more active than cefazolin against Enterobacter, indole-positive Proteus, Acinetobacter, Citrobacter, and Serratia strains. (nih.gov)

Concentration1

• Methicillin "Azlocillin sodium salt Susceptibility and Minimum Inhibitory and Concentration (MIC) Data" (PDF). (wikipedia.org)