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  • Development
  • 2005, "TGFb/Activin/Nodal Signaling is Necessary for the Maintenance of Pluripotency in Human Embryonic Stem Cells," Development, 132:1273-1282. (patentgenius.com)
  • The organizer factors chordin and noggin are required for mouse forebrain development," Nature, 403:658-661,2000. (patentgenius.com)
  • Rachel L. Carson studied biology at Johns Hopkins University in Maryland and graduated in 1933 with an MA upon the completion of her thesis, The Development of the Pronephros during the Embryonic and Early Larval Life of the Catfish (Ictalurus punctatus). (asu.edu)
  • However, our knowledge on how DNA methylation regulates early embryonic development is still limited. (embopress.org)
  • The broad and dynamic expression pattern of Zic3 provides further evidence for a complex role in embryonic development. (pubmedcentralcanada.ca)
  • The utility of C. fornicata as a model system is augmented by a wealth of comparative information on the systematic relationships, variation in embryonic development, and life histories (reviewed below). (thefreelibrary.com)
  • skeleton
  • Accordingly, the notochord serves as the axial skeleton of the embryo until other elements, such as the vertebrae, form. (biologists.org)
  • Targeted disruption of the mouse Sonic hedgehog gene shows that Shh plays a critical role in patterning of embryonic tussues, including the brain and spinal cord, the axial skeleton and limbs. (sdbonline.org)
  • structures
  • Dorsal injection of VP16-Gsc resulted in loss of head structures anterior to the hindbrain, while axial structures were unaffected, suggesting a requirement for Gsc function in head formation. (biologists.org)
  • progenitors
  • We have used conditional gene deletion of mouse β-catenin in Sox17-positive embryonic and extra-embryonic endoderm as well as vascular endothelial progenitors to address the function of canonical Wnt signalling in cell lineage formation and patterning. (biologists.org)
  • DNA methylation controls specification and clustering of the laterality organizer progenitors during early embryogenesis. (embopress.org)
  • Pathways
  • 2004, "BMP4 Supports Self-Renewal of Embryonic Stem Cells by Inhibiting Mitogen-Activated Protein Kinase Pathways," PNAS, 101(16):6027-6032. (patentgenius.com)
  • signals
  • Signals emanating from this small graft were able to divide the embryonic morphogenetic field of the host into two almost equal parts, which formed a Siamese twin. (gatech.edu)
  • Developmental
  • Organizers, which comprise groups of cells with the ability to instruct adjacent cells into specific states, represent a key principle in developmental biology. (biologists.org)
  • Proteins
  • Although most of these secreted factors bind to and antagonize the activity of Wnt and/or BMP proteins produced by non-organizer cells, these factors do not repress Wnt or BMP transcription, and are therefore not sufficient to exclude Wnt and BMP expression from the organizer. (biologists.org)
  • cells
  • The mudpuppy is an aquatic salamander commonly used by embryologists because its large embryonic cells and nuclei are easy to see. (asu.edu)
  • molecular
  • The availability of two assembled Ciona genomes, of powerful molecular tools and of extensive gene expression atlases make Ciona intestinalis a seducing model to address how chordate anteroposterior patterning can be achieved in absence of an organizer. (biologists.org)