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  • gene
  • Conditions leading to the establishment of the N (a gene dependent) and A (a gene independent) transformed states after polyoma virus infection of rat fibroblasts. (asm.org)
  • This family was identified during our investigation into the origin of the novel subgroup J envelope gene that was found several years ago in unusual strains of avian leukosis virus (ALV) (called ALV-J) in England ( 46 ). (asm.org)
  • The SU-coding region of the subgroup J env gene, in contrast, shows only 40% identity to those of the subgroup A to E viruses ( 4 , 5 , 9 , 58 ). (asm.org)
  • This suggestion was based on the fact that the subgroup J env gene included regions that showed a high degree of identity to the env gene of a previously identified avian endogenous virus called E51, a member of the ancient endogenous virus family (EAV) (see below and references 13 , 14 and 22 ). (asm.org)
  • For example, the myc gene was first identified in an avian myelocytoma virus and the ras gene was first identified in rat sarcoma virus long before they became associated with human malignancies. (rupress.org)
  • 9. The DNA of claim 5 wherein said foreign DNA sequence is an avian gene capable of being amplified concurrent with formation of concatemers by said amplicon. (patentgenius.com)
  • Analysis of the glycoprotein gene of Tacaribe virus and neutralization-resistant variants. (springer.com)
  • Retro-viruses are also valuable research tools in molecular biology and gene therapy. (encyclopedia.com)
  • The gag (group antigen) gene encodes proteins that make up the nucleocapsid of the virus as well as a matrix layer, the two of which surround the RNA. (encyclopedia.com)
  • genetic
  • His work has helped define the barriers faced by viruses as they emerge in new hosts, determine the range of transmission patterns exhibited by emerging viruses, and establish genetic models for host switching. (edu.au)
  • K. Bister, G. Ramsay, M. J. Hayman, and P. H. Duesberg, 0K10, an avian acute leukemia virus of the MC29 subgroup with a unique genetic structure, Proc. (springer.com)
  • RNAs
  • Translation of type C viral RNAs in Xenopus laevis oocytes: evidence that the 120,000-molecular-weight polyprotein expressed in Abelson leukemia virus-transformed cells is virus coded. (asm.org)
  • Evolution of virus and defective-interfering RNAs in BHK cells persistently infected with Sindbis virus. (asm.org)
  • leukemia
  • Identification of a cellular cofactor required for infection by feline leukemia virus. (springer.com)
  • Sherr C. J. Benveniste R. E., Lieber M. Type С viruses from Kirsten sarcoma - transformed mink cells со - cultivated with primate cells and expressing p30 antigens related to feline leukemia virus. (medkursor.ru)
  • In agreement with the essential role of the PBS in initiation and completion of reverse transcription ( 35 , 47 , 62 ), we previously observed a strong restriction in transduction of Akv murine leukemia virus (MLV) vectors with PBSs having only partial (PBS-XXX) or no [PBS-UMU and PBS-Met(i)int] homology with the 3′ end of any known murine tRNA molecule ( 32 ). (asm.org)
  • The family Retroviridae includes such important human pathogens as human immunodeficiency virus ( HIV ) and human Tlymphotropic virus (HTLV), the causes of AIDS and adult T-cell leukemia respectively. (encyclopedia.com)
  • subgroup
  • None of the 61 alv6 chickens contained detectable virus or produced antibody against subgroup A ALV. (mysciencework.com)
  • Virus and/or antibody against subgroup A ALV was detected in 34 of the 43 alv11 chickens, whereas 51 of 52 line 0 birds were viremic and/or produced antibody. (mysciencework.com)
  • Strand M., August J. T. Purification and analysis of a gross murine oncornavirus protein with a molecular weight of about 12 000 specific for the gross virus subgroup. (medkursor.ru)
  • glycoprotein
  • Normal DBA/2 mouse cells synthesize a glycoprotein which interferes with MCF virus infection. (springer.com)
  • Hexagonal glycoprotein arrays from Sindbis virus membranes. (asm.org)
  • Anti-idiotypic antibodies induce neutralizing antibodies to rabies virus glycoprotein. (asm.org)
  • influenza
  • He has studied the emergence and spread of avian influenza virus, dengue virus, HIV, hepatitis C virus, myxoma virus, RHDV and Yersinia pestis . (edu.au)
  • In this study, we show that insertion of the SIINFEKL peptide into the stalk of influenza A virus neuraminidase (NA) does not detectably modify NA folding, degradation, transport, or sp. (jimmunol.org)
  • Marek's
  • 1. A substantially biologically pure amplicon derived from a Marek's disease virus as a DNA fragment thereof, wherein said amplicon contains all cis-acting functions required for DNAreplication, and in the presence of helper virus, said amplicon infects host cells and replicates, thereby forming high molecular weight concatemers of DNA. (patentgenius.com)
  • 4. An amplicon as described in claim 1 wherein said Marek's disease virus is strain 281 MI/1. (patentgenius.com)
  • 12. The method of claim 11 wherein said Marek's disease virus is strain 281 MI/1. (patentgenius.com)
  • mammary
  • Superantigens of mouse mammary tumor virus. (springer.com)
  • Expression of mouse mammary tumor virus superantigen mRNA in the thymus correlates with kinetics of self-reactive T-cell loss. (springer.com)
  • B cells are essential for murine mammary tumor virus transmission, but not for presentation of endogenous superantigens. (springer.com)
  • Sarkar N. H., Taraschi N. E., Pomenti A. A. Polypeptides of the mous mammary tumor virus. (medkursor.ru)
  • Taraschi N. Effect of trypsin on mouse mammary tumo virus. (medkursor.ru)
  • Modulation of mouse mammary tumor virus production in the MJY-alpha cell line. (asm.org)
  • Discovery
  • Tumor virologists additionally recognized that viruses could serve as powerful discovery tools, leading to revolutionary breakthroughs in the 1970s and 1980s that included the concept of the oncogene, the identification of the p53 tumor suppressor, and the function of the retinoblastoma tumor suppressor. (aacrjournals.org)
  • The study of this virus family has led to the discovery of oncogenes , resulting in a quantum advance in the field of cancer genetics. (encyclopedia.com)