AutophagyLysosomesLysosomal-Associated Membrane Protein 2EndosomesCathepsin DEndocytosisLysosome-Associated Membrane GlycoproteinsChloroquineCathepsin BProteasome Endopeptidase ComplexProteolysisProtein TransportPhagosomesUbiquitinMicrotubule-Associated ProteinsModels, BiologicalSignal TransductionApoptosisCell LineCell Line, TumorCells, CulturedCytosolProteinsHeLa CellsApoptosis Regulatory ProteinsBiological TransportMutationUbiquitin-Activating EnzymesLiverTOR Serine-Threonine KinasesClass III Phosphatidylinositol 3-KinasesVacuolesAdenineSirolimusMembrane ProteinsMitochondrial DegradationCell SurvivalMicroscopy, Electron, TransmissionCell DeathRNA, Small InterferingMitochondriaEndoplasmic Reticulum StressRNA InterferenceReactive Oxygen SpeciesGene Knockdown TechniquesMultiprotein ComplexesCytoprotectionStarvation