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  • 2017
  • In 2017, two CAR T-cell therapies were approved by the Food and Drug Administration (FDA), one for the treatment of children with acute lymphoblastic leukemia (ALL) and the other for adults with advanced lymphomas. (cancer.gov)
  • 1949
  • Opinions on the origin of the muscle car vary, but the 1949 Oldsmobile Rocket 88 , created in response to public interest in speed and power, is often cited as the first muscle car. (wikipedia.org)
  • asserts
  • Henshaw further asserts that the muscle car was designed for straight-line speed, and did not have the "sophisticated chassis", "engineering integrity", or "lithe appearance" of European high-performance cars. (wikipedia.org)
  • Another version of the story asserts that the Auto-Icon does vote, but only on occasions when the votes of the other Council members are equally split. (ucl.ac.uk)
  • muscle cars
  • The Merriam-Webster dictionary defines muscle cars as "any of a group of American-made 2-door sports cars with powerful engines designed for high-performance driving. (wikipedia.org)
  • Sold at an affordable price, muscle cars are intended for street use and occasional drag racing . (wikipedia.org)
  • According to Muscle Cars , a book written by Peter Henshaw, a "muscle car" is "a product of the American car industry adhering to the hot rodder 's philosophy of taking a small car and putting a large-displacement engine in it. (wikipedia.org)
  • "From the mid-sixties to the mid-seventies, what we now think of as muscle cars were more commonly called 'Supercars,' often (though not always) spelled with a capital S." This term described the " dragstrip bred" affordable mid-size cars of the 1960s and early 1970s that were equipped with large, powerful V8 engines and rear-wheel-drive . (wikipedia.org)
  • Opinions vary as to whether high-performance full-size cars , compacts , and pony car qualify as muscle cars. (wikipedia.org)
  • mechanics
  • Info concerning Elgin Community College auto mechanics, registering for elective courses, and taking free tests online. (auto-mechanics.net)
  • If you complete the auto mechanics major, for example, there are a variety of specializations that may appeal to you such as gasoline engine repair, racing engine design, or mechanical engineering. (auto-mechanics.net)
  • Further, due to advances in automotive engineering, there is a growing shortage of auto mechanics graduates, and highly-skilled engineers in general. (auto-mechanics.net)
  • industry
  • "In 1966, the supercar became an official industry trend" as the four domestic automakers "needed to cash in on the supercar market" with eye-catching, heart-stopping cars. (wikipedia.org)
  • Our road cars have to meet all the regulations, but they also need other distinct capabilities like being able to be driven on a race track, and there are very stringent safety regulations," continues Mr Grose, who has worked in the industry for more than a quarter of a century and is based at McLaren's Woking campus. (telegraph.co.uk)
  • The automobile industry, mainly in the beginning of the 20th century when the high motorization rates were not an issue, had also an important public role, which was the creation of jobs. (wikipedia.org)
  • After in-depth analysis of our specific market area, national statistics on the car wash industry, and detailed evaluation of nine car wash operations in the area, we expect to generate sales revenues of $667,508 in the first year of operation. (encyclopedia.com)
  • Because there are no other car wash operations within a four mile radius of our site location, we feel confident our predicted growth will, ataminimum, follow industry trends. (encyclopedia.com)
  • moves
  • With the new chart, no slower vehicle moves when a faster vehicle does not, so the collision cannot happen, since, as with the first edition, a faster car always moves first in a phase. (sjgames.com)
  • commonly
  • One of the most commonly recounted is that the Auto-Icon regularly attends meetings of the College Council, and that it is solemnly wheeled into the Council Room to take its place among the present-day members. (ucl.ac.uk)
  • debut
  • Mazda CEO Takashi Yamanouchi is interviewed while the Mazda6 is shown during it's North American debut at the LA Auto Show in Los Angeles, Thursday, Nov. 29, 2012. (yahoo.com)
  • The all-new sports car will make its world debut in Paris alongside the redesigned Range Rover from its sister brand Land Rover. (edmunds.com)
  • road
  • Examples of the use of the supercar description for the early muscle models include the May 1965 Car Life road test of the Pontiac GTO along with how " Hurst puts American Motors into the Supercar club with the 390 Rogue" (the SC/Rambler ) to fight in "the Supercar street racer gang" market segment. (wikipedia.org)
  • The 75,000sq ft MCTC, which will be fully operational in 2020, currently has around 50 engineers working on the in-house manufacturing of carbon-fibre "tubs" for the company's road cars. (telegraph.co.uk)
  • This automobile was a symbol of status, at a time where most vehicles on the road would be Ford Model T, any car on the road was a luxury in the early 1900's specified for that of the upper class. (uvic.ca)
  • Every time we head out on the road, we check our kiddo's car seat once, then check it twice to make sure it's properly. (inhabitat.com)
  • largely
  • Until recently, the use of CAR T-cell therapy has been restricted to small clinical trials, largely in patients with advanced blood cancers. (cancer.gov)
  • Dr. June has led a series of CAR T cell clinical trials, largely in patients with leukemia. (cancer.gov)
  • Similarly, though personal experiences can change your outlook towards an automobile, the era upon which my parents and their siblings grew up, an overwhelming influence of Though taken largely from a personal perspective, these stories are windows of insight that provide a personal history for future generations to enjoy. (uvic.ca)
  • years
  • In just the last few years, progress with CAR T cells and other ACT approaches has greatly accelerated, with researchers developing a better understanding of how these therapies work in patients and translating that knowledge into improvements in how they are developed and tested. (cancer.gov)
  • Bentham had originally intended that his head should be part of the Auto-Icon, and for ten years before his death (so runs another story) carried around in his pocket the glass eyes which were to adorn it. (ucl.ac.uk)
  • The wax head was therefore substituted, and for some years the real head, with its glass eyes, reposed on the floor of the Auto-Icon, between Bentham's legs. (ucl.ac.uk)
  • When you lease a car for two years, you are paying for two years of depreciation in monthly payments plus interest. (in.gov)
  • Leasing puts the driver in a new car every two or three years. (in.gov)
  • The property on which The Dirt Buster is to be located was the site of a car wash approximately ten years ago. (encyclopedia.com)
  • service
  • There is a distinct difference, to the attuned ear, between the highly respectful honk used in a service station during an annual car inspection in response to the command 'Sound your horn' and the just perceptibly more urgent, less deferential beep that announces to the inhabitants of a domicile that a summoned taxi or car-pool van impatiently awaits. (newyorker.com)
  • The new problems and how AirBnB are doing service auto discovery. (slideshare.net)
  • The Dirt Buster was designed by entrepreneurs wishing to provide a high quality car wash service in a virtually untapped market. (encyclopedia.com)
  • The original tunnel's one hundred-twenty foot length, versus today's standard ninety foot tunnel length, provides a significant service advantage over other car washes in the area. (encyclopedia.com)
  • The bottom line is that most car wash operators sacrifice service to minimize costs. (encyclopedia.com)
  • To capitalize on these demographic factors and concentrate on the unique demands each group asks of the market, our facility will incorporate both a full-service tunnel operation (for those who wish to allow our service team to clean their car) and a self-service facility (for those who wish to take a more active role in their car's maintenance). (encyclopedia.com)
  • world
  • 137 PS) at 3,600 rpm and 263 pound force-feet (357 N⋅m) of torque at a lazy 1800 rpm [and] no mid-range car in the world, except the Hudson Hornet , came close to the Rocket Olds performance potential. (wikipedia.org)
  • Nidec's electric motors are already used in tens of millions of automobiles across the world and Auto China 2018 provides an excellent opportunity for the company to showcase its latest technologies. (mynewsdesk.com)
  • Once
  • Once the collected T cells have been engineered to express the antigen-specific CAR, they are "expanded" in the laboratory into the hundreds of millions. (cancer.gov)
  • Flashed lights, for instance, once only hinted that a police car was lurking around the corner, but now, flicked demurely, say 'Do it' and 'Thank you,' much as the Italian word prego says both 'Please' and 'You're welcome. (newyorker.com)
  • type
  • The advantages of car usage include on-demand and door-to-door travel, and are not easily substituted by cheaper alternative modes of transport, with the present level and type of auto specific infrastructure in the countries with high auto usage. (wikipedia.org)
  • This type of car wash operation will be one of only three such facilities in the area. (encyclopedia.com)
  • roads
  • the social construction within the cities they resided, revolved around the automobile, this in turn paved new roads upon which both could travel. (uvic.ca)
  • normal car
  • Additionally, our vehicles have to be designed for serviceability and repairability, and other demands that you would expect from a normal car. (telegraph.co.uk)
  • Brands
  • Look for notable debuts from Audi, BMW and Volkswagen, too, in addition to groundbreaking, new cars from the brands we don't get here in the U.S. Check back here for full coverage starting September 27. (edmunds.com)
  • According
  • According to a survey by research group Gartner Inc., these are the top 10 electronic features people want in cars. (latimes.com)
  • According to the Department for Transport , the real cost of running a car has dropped by 9% between 1980 and 2007. (wikipedia.org)
  • another
  • CAR T cells are the equivalent of "giving patients a living drug," explained Renier J. Brentjens, M.D., Ph.D., of Memorial Sloan Kettering Cancer Center in New York, another early leader in the CAR T-cell field. (cancer.gov)
  • When the Paris show opens its doors in late September, the world's automakers will have had seven months since the Geneva show in early March to prepare another wave of interesting new production cars and never-before-seen concepts. (edmunds.com)
  • Another private benefit car owners enjoy, is comfort . (wikipedia.org)
  • market
  • The manufacturing rights for the pre-war Perry car were for sale so in January 1919 A. Harper & Sons & Bean bought them for £15,000, giving it a quick entry into the car market. (wikipedia.org)
  • popular
  • Leasing became popular when businesses wanted to operate automobile fleets while avoiding the high cost of ownership and maintenance. (in.gov)
  • Compared to other popular modes of passenger transportation, the car has a relatively high cost per person-distance traveled. (wikipedia.org)
  • Year
  • Kyoto, Japan: Today, Nidec Corporation announced that its automotive division will exhibit at Auto China 2018 to be held in Beijing, China in April - May this year. (mynewsdesk.com)
  • Edition
  • A 3-page article from 1920 on technical aspects of the Standard Steam Car appears in Floyd Clymer's Historical Motor Scrapbook, Steam Car Edition, published in 1945. (wikipedia.org)
  • full
  • With the new chart a car moving at the same speed will move full inches on the first and third phases of the turn and a half-inch on the sixth phase. (sjgames.com)
  • known
  • Part of the explanation lies with a phenomena known as ' molecular mimicry ,' defined as the possibility that the immune system will mistake a self-structure with a foreign (usually pathogen derived) peptide and thereby cause auto-immune harm. (greenmedinfo.com)
  • company
  • The company began making cars in 1919 and diversified into light commercial vehicles in 1924. (wikipedia.org)
  • The launch of an under-developed new model in 1928 worsened sales, and the company stopped making cars in 1929. (wikipedia.org)
  • The Standard Steam Car was an American steam car manufactured by the Standard Engineering Company of St Louis, Missouri from 1920 until 1921. (wikipedia.org)
  • The company that owns the automobile. (in.gov)
  • Sold
  • There's about a million and a half cars that won't be sold (in the United States in 1994). (latimes.com)
  • At the end of the lease, the automobile can be either sold to you or someone else for its value at that point. (in.gov)
  • Show
  • The Los Angeles Auto Show opened to the public Nov. 30. (yahoo.com)
  • As the first major European show of the season, the 2012 Paris Auto Show is guaranteed to have its share of big-time debuts and significant showcars. (edmunds.com)
  • public
  • Public costs related to the car are several including congestion and effects related to emissions. (wikipedia.org)
  • In countries deprived from wide door-to-door public transport and with low density, such as Australia , the automobile plays an important role on the mobility of citizens. (wikipedia.org)
  • Hence cars tend to dominate in rural and suburban environments with public economic gains. (wikipedia.org)
  • companies
  • Car companies are constantly devising new ways to entice parents to buy their vehicles -- but that usually means. (inhabitat.com)
  • maker
  • GM Recalls Blazers and Jimmys: The auto maker said it is recalling 111,000 1995 Chevrolet Blazer and GMC Jimmy sport utility vehicles to fix a problem that could lead to fuel-tank leakage. (latimes.com)
  • personal
  • Even though both parents came from completely different upbringings, they both shared foundational personal experiences and similarities, in regards to automobiles. (uvic.ca)
  • next
  • Next, using a disarmed virus, the T cells are genetically engineered to produce receptors on their surface called chimeric antigen receptors, or CARs. (cancer.gov)
  • The next month, auto workers at Chrysler won recognition of the UAW as their representative in a sit-down strike. (wikipedia.org)
  • cells
  • Co-stimulatory signaling domains have been added to newer generations of CAR T cells to improve their ability to produce more T cells after infusion and survive longer in the circulation. (cancer.gov)
  • Driving CAR T cells forward. (cancer.gov)
  • Nevertheless, researchers caution that, in many respects, it's still early days for CAR T cells and other forms of ACT, including questions about whether they will ever be effective against solid tumors like breast and colorectal cancer. (cancer.gov)
  • The different forms of ACT "are still being developed," said Steven Rosenberg, M.D., Ph.D., chief of the Surgery Branch in NCI's Center for Cancer Research (CCR), an immunotherapy pioneer whose lab was the first to report successful cancer treatment with CAR T cells . (cancer.gov)
  • As its name implies, the backbone of CAR T-cell therapy is T cells , which are often called the workhorses of the immune system because of their critical role in orchestrating the immune response and killing cells infected by pathogens. (cancer.gov)
  • These receptors are "synthetic molecules, they don't exist naturally," explained Carl June, M.D., of the University of Pennsylvania Abramson Cancer Center, during a recent presentation on CAR T cells at the National Institutes of Health campus. (cancer.gov)
  • The final step is the infusion of the CAR T cells into the patient (which is preceded by a "lymphodepleting" chemotherapy regimen). (cancer.gov)