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  • cells
  • Bone-marrow was collected from in the antero-superior iliac crest and mononuclear stem-cells were isolated by centrifugation in the density rate Ficoll-Hypaque 1.077 media. (clinicaltrials.gov)
  • bone marrow cells) in a randomized, placebo controlled trial. (bioportfolio.com)
  • In order to study the transplantation effect of hematopoetic stem cells from beta-thalassemia induced pluripotent stem cells. (bioportfolio.com)
  • After desirable blood-forming cells with this antigen are removed from the patient's blood, high-dose chemotherapy, monoclonal antibody therapy, or radiation may be used to purge the marrow of diseased cells. (thefreedictionary.com)
  • Healthy CD34+ cells capable of rebuilding the bone marrow are then returned to the patient and stimulated to reproduce. (thefreedictionary.com)
  • Hepatosplenic T-cell lymphoma is a systemic neoplasm comprising medium-sized cytotoxic T-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow. (wikipedia.org)
  • These agents, however, cannot discriminate between the leukaemia or neoplastic cells, and the hematopoietic stem cells within the bone marrow. (wikipedia.org)
  • a donor's healthy bone marrow reintroduces functional stem cells to replace the cells lost in the host's body during treatment. (wikipedia.org)
  • citation needed] Possible mechanisms of recovery include: Generation of heart muscle cells Stimulation of growth of new blood vessels to repopulate damaged heart tissue Secretion of growth factors Assistance via some other mechanism It may be possible to have adult bone-marrow cells differentiate into heart muscle cells. (wikipedia.org)
  • Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells. (wikipedia.org)
  • The crowding that results from such cells makes the bone marrow unable to produce healthy blood cells. (wikipedia.org)
  • This divides leukemias into lymphoblastic or lymphocytic leukemias and myeloid or myelogenous leukemias: In lymphoblastic or lymphocytic leukemias, the cancerous change takes place in a type of marrow cell that normally goes on to form lymphocytes, which are infection-fighting immune system cells. (wikipedia.org)
  • In myeloid or myelogenous leukemias, the cancerous change takes place in a type of marrow cell that normally goes on to form red blood cells, some other types of white cells, and platelets. (wikipedia.org)
  • Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells. (wikipedia.org)
  • Katakowski's current work hypothesizes that rejuvenating the bone marrow by autologous heterochronic transplantation of cells could extend healthy lifespan. (wikipedia.org)
  • Stem cells from the bone marrow, which is derived from mesoderm, can differentiate into liver, lung, GI tract and skin, which are derived from endoderm and mesoderm. (wikipedia.org)
  • leukemic
  • Rarely, the first sign of leukemia may be the development of a solid leukemic mass or tumor outside of the bone marrow, called a chloroma. (wikipedia.org)
  • Tumors
  • Leukemias and lymphomas both belong to a broader group of tumors that affect the blood, bone marrow, and lymphoid system, known as tumors of the hematopoietic and lymphoid tissues. (wikipedia.org)
  • Wright's group were the first to demonstrate use of the drug in solid tumors, as opposed to leukemias, which are a cancer of the marrow. (wikipedia.org)
  • group
  • Working under the supervision of Bruce (AACR Award), and in association with Till and McCulloch and a vibrant group of graduate students and post-doctoral fellows, Eaves completed his PhD in Medical Biophysics at the University of Toronto with a thesis entitled Studies on the Control of Murine Bone Marrow Function (1974). (wikipedia.org)
  • doses
  • The dose of chemotherapy that can be given to an individual is limited because it is unsafe in high doses and can seriously damage the bone marrow, creating high risk of serious infection. (cochrane.org)
  • years
  • As Head of Hematology at the British Columbia Cancer Agency and the University of British Columbia for 18 years (1985-2003) he engineered the building of one of the first and largest bone marrow transplant programs in Canada. (wikipedia.org)