• Currently, the only FDA-approved cell-based therapy for cartilage defects involves autologous chondrocyte implantation: chondrocytes harvested from low-contact areas are expanded in vitro and then re-injected directly into the damaged site 1 . (nature.com)
  • Autologous chondrocyte implantation (ACI) involves harvesting healthy cartilage cells from the patient, which are then cultured and expanded in the laboratory. (surgeonsync.com)
  • Matrix-assisted autologous chondrocyte implantation (MACI) is a variation of ACI that involves seeding the expanded chondrocytes onto a biocompatible scaffold before implantation. (surgeonsync.com)
  • Autologous chondrocyte implantation involves harvesting chondrocytes from healthy tissue, expanding the cells in vitro, and implanting the expanded cells into the chondral defect. (arkansasbluecross.com)
  • Osteochondral grafts and autologous chondrocyte implantation (ACI) attempt to regenerate hyaline-like cartilage and thereby restore durable function. (arkansasbluecross.com)
  • Methods to improve the first-generation ACI procedure have been developed, including the use of a scaffold or matrix-induced autologous chondrocyte implantation (MACI) composed of biocompatible carbohydrates, protein polymers, or synthetics. (arkansasbluecross.com)
  • In this interview, Dr. Katz discusses why third-generation autologous chondrocyte implantation (ACI) is superior to microfracture for focal chondral defects of the knee joint - a topic applied to the generation of thought provoking NBME style questions for self-evaluation. (finfactbuddy.com)
  • Various surgical techniques and interventions are utilized to achieve this goal, including autologous chondrocyte implantation (ACI), microfracture, osteochondral grafting, and other emerging technologies. (finfactbuddy.com)
  • Regenerative medicine approaches, including autologous chondrocyte implantation (ACI) and matrix-assisted autologous chondrocyte transplantation (MACT), involve harvesting healthy cartilage cells from the patient, expanding them in the lab, and then implanting them into the damaged area. (spinewala.com)
  • Autologous chondrocyte implantation (ACI) involves the removal of cartilage cells from your own body. (activeoa.com)
  • 2011). The technique of matrix-induced autologous chondrocyte implantation (MACI) involves two surgical procedures. (thesportsphysiotherapist.com)
  • Hambly K, Bobic V, Wondrasch B, Van Assche and Marolvits S. Autologous Chondrocyte Implantation Postoperative Care and Rehabilitation. (thesportsphysiotherapist.com)
  • ACI is a two-step surgical procedure which necessitates chondral harvesting from a non-weight-bearing area of the knee and external chondrocytes expansion in a dedicated laboratory [ 9 , 10 ]. (springer.com)
  • Second- and third-generation techniques include combinations of autologous chondrocytes, scaffolds, and growth factors. (arkansasbluecross.com)
  • The culturing of chondrocytes is considered by the U.S. Food and Drug Administration (FDA) to fall into the category of manipulated autologous structural cells, which are subject to a biologic licensing requirement. (arkansasbluecross.com)
  • MACI® consists of autologous chondrocytes which are cultured onto a bioresorbable porcine-derived collagen membrane. (arkansasbluecross.com)
  • A number of other second-generation methods for implanting autologous chondrocytes in a biodegradable matrix are currently in development or testing or are available outside of the United States. (arkansasbluecross.com)
  • The first involves arthroscopic debridement of the lesion back to a stable edge and an initial harvest of healthy cartilage, the chondrocytes of which are then isolated and expanded ex-vivo. (thesportsphysiotherapist.com)
  • Fat transfer to the breasts, also known as autologous fat grafting or fat transfer breast augmentation, is a popular procedure that offers a natural alternative to traditional breast augmentation with implants. (divinecosmeticsurgery.com)
  • Facial fat grafting, also known as autologous fat transfer or fat injection, is a cosmetic procedure that involves the removal of excess fat from one area of the body, typically through liposuction, and then transferring that fat to enhance or rejuvenate the face. (fortlauderdaleplasticsurgery.com)
  • Harvesting of fat - Liposuction from abdomen, back or thighs is commonly done to collect fat. (drpreetishbhavsar.com)
  • The fat tissue is harvested by liposuction, washed, and liquified so that it can be injected into the area of interest. (breastcancertalk.net)
  • This procedure involves harvesting autologous fat (fat from the patient's own body) using liposuction techniques and then injecting it into the trunk, breasts, scalp, arms, and/or legs. (codingahead.com)
  • CPT code 15771 should be used when billing for a fat grafting procedure involving the harvesting of autologous fat using liposuction techniques and injecting it into the trunk, breasts, scalp, arms, and/or legs, with 50 cc or less of fat injectate. (codingahead.com)
  • In this technique, healthy cartilage and bone are harvested from a non-weight-bearing area of the joint and transplanted into the defect. (surgeonsync.com)
  • Similar to autograft transplantation, allograft transplantation involves transplanting cartilage and bone from a donor. (surgeonsync.com)
  • Débridement involves the removal of synovial membrane, osteophytes, loose articular debris, and diseased cartilage and is capable of producing symptomatic relief. (arkansasbluecross.com)
  • Desired features of articular cartilage repair procedures are the ability (1) to be implanted easily, (2) to reduce surgical morbidity, (3) not to require harvesting of other tissues, (4) to enhance cell proliferation and maturation, (5) to maintain the phenotype, and (6) to integrate with the surrounding articular tissue. (arkansasbluecross.com)
  • In addition to the potential to improve the formation and distribution of hyaline cartilage, use of a scaffold with MACI eliminates the need for harvesting and suture of a periosteal or collagen patch. (arkansasbluecross.com)
  • The initial stage is an arthroscopic procedure where healthy cartilage is harvested from a non-weight bearing joint of your own body and sent to the laboratory, where the cartilage cells are extracted and cultured (multiplied) for a period of 3 to 5 weeks. (activeoa.com)
  • These procedures can be performed in one stage as they do not require harvesting of healthy cartilage tissue. (activeoa.com)
  • Microfracture involves the creation of multiple holes at the damaged site to introduce blood supply and stimulate new cartilage to grow. (activeoa.com)
  • This article will discuss a relatively new technique, Matrix-induced autologous cartilage implantation or MACI, including an overview of technique, mid-term outcomes and of course the rehabilitation implications for physiotherapists. (thesportsphysiotherapist.com)
  • What Is Matrix-Induced Autologous Cartilage Implantation (MACI)? (thesportsphysiotherapist.com)
  • This paper describes successful treatment in three patients with Achilles tendonosis and interstitial tears using with non-manipulated autologous adipose derived stem/stromal cells and high-density platelet rich plasma concentrates (or bone marrow/platelet concentrate combination). (journalofprolotherapy.com)
  • Introduce a safe, practical, and effective protocol for minimally invasive treatment of Achilles tendon tears using non-manipulated autologous adipose-derived tissue stromal vascular fraction with additive of high-density platelet-rich plasma or bone marrow concentrates. (journalofprolotherapy.com)
  • Autologous AD-MSC [adipose-derived MSC (mesenchymal stem cell)] involves harvesting fat from the patient by isolating the stem and regenerative cells and administering the cells back to the patient. (drcalapai.com)
  • Expanded natural killer cells killed both allogeneic and autologous primary myeloma cells avidly via a perforin-mediated mechanism in which the activating receptor NKG2D, natural cytotoxicity receptors, and DNAX-accessory molecule-1 played a central role. (haematologica.org)
  • This article contains highlights of "Guidelines for Pre- allogeneic or autologous, depending on the source of venting Opportunistic Infections among Hematopoi- the transplanted hematopoietic progenitor cells. (cdc.gov)
  • For the purposes of this document, HSCT is defined of the CDC, the Infectious Diseases Society of America, as any transplantation of blood or marrow-derived he- and the American Society of Blood and Marrow Trans- matopoietic stem cells, regardless of transplant type plantation," which was published in the Morbidity and (allogeneic or autologous) or cell source (bone marrow, Mortality Weekly Report [1]. (cdc.gov)
  • There pediatric and adult autologous and allogeneic HSCT patients. (cdc.gov)
  • Dr. Freytes explained that bone reconstructions, such as craniofacial reconstruction, often involve "autologous tissue grafting, a method limited by harvesting difficulties, donor site morbidity, and the clinicians' ability to contour delicate 3-D shapes. (genengnews.com)
  • Foothill Ranch, CA, June 06, 2008 --( PR.com )-- A traditional, "open" surgical spine procedure typically involves the surgeon making a long incision, from either an anterior or posterior approach, dissecting and retracting layers of tissue as needed to provide both visualization and access to the affected area. (pr.com)
  • The rate of fat "take" is normally 70-90% but this can vary between 30-90%, depending on the quality of the fat harvest, blood supply of the recipient tissue, technique used, density and amount of scarring present at the recipient site. (cranfordhouseplasticsurgery.com.au)
  • Another option worth considering is autologous tissue transfer, a procedure in which a skilled plastic surgeon uses your own tissue to recreate the breasts. (plasticsurgery.org)
  • Mastectomy patients could choose to rebuild the breast with an implant or to have autologous tissue transfer, depending on their preference and individual case. (plasticsurgery.org)
  • With the latter, autologous tissue - another way to say your own tissue - is taken from a donor site on your abdomen, back, buttocks or thighs to reconstruct your breast. (plasticsurgery.org)
  • Depending on your unique needs and preferences, there are several varieties of autologous tissue transfer. (plasticsurgery.org)
  • A transverse rectus abdominis myocutaneous flap harvests tissue from your lower abdomen, incorporating skin, fat and sometimes part of your abdominal muscle. (plasticsurgery.org)
  • A newer type of breast reconstruction technique involves the transfer of fat tissue from one part of the body to the reconstructed breast. (breastcancertalk.net)
  • Autologous tissue breast reconstruction is usually reserved for after radiation therapy, so that the breast and chest wall tissue damaged by radiation can be replaced with healthy tissue from elsewhere in the body. (breastcancertalk.net)
  • The aim of this paper is to discuss the general overview of the quality assurance and quality control implemented in the manufacturing of cell and tissue product, with emphasis on our experience in the manufacturing of MyDerm ® , an autologous bilayered human skin substitute. (biomedcentral.com)
  • For grafting of autologous soft tissue (fat, dermis, or fascia) harvested by direct excision, use code 15769 . (codingahead.com)
  • A disposable, closed syringe microcannula system was employed to harvest the adipose tissue complex via standard lipoaspiration techniques. (journalofprolotherapy.com)
  • The percutaneous use of a combination of autologous adipose tissue complex (inclusive of its heterogeneous cell populations and native bioactive scaffold) and either HD-PRP or HD-PRP/BMAC combination appear as promising options for non-surgical management of Achilles tendonosis and partial thickness interstitial tears. (journalofprolotherapy.com)
  • PRP involves injecting a concentrated solution of the patient's own platelets into the injured area, releasing growth factors and stimulating tissue regeneration. (spinewala.com)
  • Increasingly, minimally invasive techniques are becoming the preferred method for autologous bone graft procedures. (pr.com)
  • The present gold standard in bone grafting is autologous bone taken from the iliac crest or ribs, however, this process is related to significant morbidity and postoperative pain owing to an added graft harvesting process. (industryarc.com)
  • Additional bone graft substitutes and biologics involve allografts, demineralized bone matrix, bone morphogenetic protein, and bioactive glass. (industryarc.com)
  • For the lacrimal groove, hyaluronic acid and autologous fat graft can be used as fillers. (forbeautylove.com)
  • Utilising the patient's own stem cells and growth factors harvested from the scalp, this autologous stem-cell hair-restoration treatment stimulates the existing hair follicles to grow hair shafts faster and thicker, while reducing hair loss. (expatliving.sg)
  • However, lymph stasis is probably not involved significantly in angiosarcoma of the scalp. (medscape.com)
  • This procedure involves transplanting blood stem cells, which travel to the bone marrow where they produce new blood cells and promote growth of new marrow. (medicaljump.com)
  • This minimally invasive procedure involves harvesting fat from one area of your body and carefully re-implanting it in the target area, guaranteeing a safe and natural solution. (mindful-minerals-store.com)
  • The procedure involves injecting the filler into specific areas of the cheeks to restore lost volume and create a fuller appearance. (docvatsa.com)
  • The fat harvested from donor areas is carefully selected to improve body proportions and create a more sculpted physique. (divinecosmeticsurgery.com)
  • Fat grafting requires a sufficient amount of donor fat to be harvested from other areas of your body. (divinecosmeticsurgery.com)
  • In autologous stem cell transplants, the patient is their own stem cell donor. (leukaemia.org.au)
  • involves the use of stem cells from a donor, which can either be a related or unrelated individual. (rx-longevity.com)
  • When a person needs a bone marrow transplant, doctors must retrieve and harvest stem cells from that individual or a donor. (popsci.com)
  • A multiport cannula, 2 to 6 mm in diameter, connected to a syringe is used to harvest the autologous fat from one or more donor sites. (codingahead.com)
  • Patients with initial Stage III or IV or UH Wilms Tumor who relapse can still be cured, with use of intense chemotherapy followed by an autologous stem cell transplant (this involves harvesting the patient's blood or marrow stem cells, followed by very high dose chemotherapy, and finally re-infusion of the patient's own stem cells to rescue the blood counts). (hopkinsmedicine.org)
  • What's the Process Involved in a Stem Cell Transplant? (dana-farber.org)
  • What is an autologous stem cell transplant? (leukaemia.org.au)
  • It's important to realise that the processes involved in a stem cell transplant are often long and complex. (leukaemia.org.au)
  • This process is called stem cell mobilisation and usually involves the use of chemotherapy in combination with colony stimulating growth factor injections - usually G-CSF. (leukaemia.org.au)
  • Stem cell therapy involves the use of stem cells to restore, regenerate, or repair tissues or organs that have been damaged due to injury or disease. (rx-longevity.com)
  • The team found that a combination of Viagra and a stem cell mobilizer called Plerixafor were able to pull stem cells out of the bone marrow and into the bloodstream (like GCSF's do), where they could be easily harvested. (popsci.com)
  • Right now, GCSFs don't work for some patients who might benefit from autologous stem cell transplants-a procedure where doctors harvest a person's own stem cells and use them to replace their unhealthy bone marrow, that's used in conditions like Hodgkin's lymphoma-because they often don't work in people who have had chemotherapy in the past. (popsci.com)
  • 1. What are the therapeutic advantages of an autologous stem cell transplant on Charlie's bone marrow and immune system? (studentsolutionsusa.com)
  • Microfracture is a technique that involves creating small holes in the subchondral bone beneath the defect. (surgeonsync.com)
  • Autologous transplants involve the use of a person's own stem cells. (medicaljump.com)
  • Autologous transplants are used to treat a number of different blood cancers. (leukaemia.org.au)
  • Autologous transplants allow the use of high-dose chemotherapy, which provides some patients with a better chance of cure or long-term control of their disease. (leukaemia.org.au)
  • It involves harvesting small grafts which are disaggregated through the Regenera Activa device. (expatliving.sg)
  • Stem cells harvested from a person's own bone marrow or blood, can safely slow progression of the most common form of the autoimmune disease, multiple sclerosis, or MS as it's usually known, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry. (news-medical.net)
  • Explanation of use of a protocol termed "Autologous Regenerative Matrix" (ARM) is explained for guided, percutaneous placement into damaged tendinous tissues. (journalofprolotherapy.com)
  • The method is safe, very well tolerated by patients, uses readily available autologous sources, and utilizes non-manipulated autologous tissues. (journalofprolotherapy.com)
  • Platelet-rich plasma (PRP) is an autologous blood concentrate that includes a natural concentration of autologous development factors and cytokines. (industryarc.com)
  • This innovative technique involves harvesting fat from one area of the patient's body, typically the abdomen, thighs, or buttocks, and then injecting it into the breasts to enhance their size, shape, and contours. (divinecosmeticsurgery.com)
  • The PETLIF surgical technique involves three steps to acquire disc height under general anesthesia. (londonspine.com)
  • Tattooing (Micropigmentation): This technique involves implanting pigment into the skin to match the surrounding areas, creating a more uniform skin tone. (thesshclinic.com)
  • Most clinical trials which utilize ADSCs for OA treatment have been based on the autologous cells from the stromal vascular fraction, as have most of the in vivo studies ( 6 , 7 ). (spandidos-publications.com)
  • The breast augmentation by fat transfer procedure begins with the harvesting of fat cells from another part of your body, such as your thighs, abdomen, or buttocks. (cranfordhouseplasticsurgery.com.au)
  • This involves harvesting fat cells from your body. (achaobgyn.com)
  • In such cases, stem cells can be harvested, or grown, before you start chemotherapy or radiation treatment. (medicaljump.com)
  • They typically involve harvesting your cells before beginning a damaging therapy to cells like chemotherapy or radiation. (medicaljump.com)
  • In some cases, stem cells are harvested from a patient's own blood to be transplanted back after conditioning treatment that kills cancerous cells. (dana-farber.org)
  • involves the use of a patient's own stem cells, which are harvested and then transplanted back into the patient's body. (rx-longevity.com)
  • It takes multiple days of injections with GCSF before stem cells can be harvested, under current clinical practice. (popsci.com)
  • 2. Before harvesting stem cells, a cytokine growth factor is administered to the patient. (studentsolutionsusa.com)
  • If the tumor is too large to resect or involves both kidneys, we will take a small biopsy and then use chemotherapy to shrink the tumor(s), followed by a second surgery 6-9 weeks later. (hopkinsmedicine.org)
  • Fat transfer to the breasts typically involves small incisions that result in minimal scarring. (divinecosmeticsurgery.com)
  • Arthroscopy involves making small incisions and using a tiny camera called an arthroscope to visualize the joint. (surgeonsync.com)
  • Autologous fat transfer, also known as fat grafting, is a technique that harnesses your body's natural fat to restore volume and enhance features. (mindful-minerals-store.com)
  • At One Skin Clinic, our skilled practitioners excel in autologous fat transfer, delivering stunning results tailored to your unique facial anatomy and desired outcome. (mindful-minerals-store.com)
  • Autologous Fat Grafting, also know as Fat Transfer, involves harvesting the patient's fat from one area of the body and injecting it into another part of the body. (kdsaesthetics.com)
  • Facial fat grafting, also called autologous fat grafting and micro-lipoinjection, involves harvesting fat from other areas of the body such as your abdomen, thighs, or buttocks, which are most similar to the texture of your face. (shinecosmeticsurgery.com)
  • For under-eye bags, many techniques can be used, involving making an incision inside or outside the eyelids, or lipolysis. (forbeautylove.com)
  • The procedure is appropriate for cases where 50 cc or less of autologous fat is used for injection. (codingahead.com)
  • For many, the road to recovery might involve a mastectomy, a surgical procedure that removes one or both breasts. (plasticsurgery.org)
  • In short, the investigators suggested that antiretroviral therapy-associated lipodystrophy, including lipoatrophy, is the result of a complex remodeling process of adipocytes involving variable combinations of apoptosis, defective lipogenesis, and increased metabolic activity in different adipose areas of the body. (prn.org)
  • If the Wilms Tumor involves only one kidney and is not excessively large or extending far into major blood vessels, surgery will entail removal of the entire tumor along with the involved kidney. (hopkinsmedicine.org)
  • Disseminated Intravascular Coagulation (DIC) Disseminated intravascular coagulation (DIC) involves abnormal, excessive generation of thrombin and fibrin in the circulating blood. (msdmanuals.com)
  • The second surgery (generally months later and via arthrotomy) involves the re-implantation into the knee as a cell-scaffold construct and held in place with a fibrin glue. (thesportsphysiotherapist.com)
  • Skin Grafting: This involves taking healthy, pigmented skin from one area of the body and transplanting it to the affected areas. (thesshclinic.com)
  • This involves tightening loose skin, smoothing wrinkles and fine lines, improving facial contours, and addressing sagging or drooping in the lower face and neck areas. (fortlauderdaleplasticsurgery.com)
  • Although it's too early to say if this treatment will work in humans, it's a logical approach, says David Porter, the Jodi Fisher Horowitz Professor in Leukemia Care Excellence at the Perelman School of Medicine at the University of Pennsylvania, who wasn't involved in the study. (popsci.com)
  • Phototherapy: This involves exposing the skin to ultraviolet A or B light, either alone or in combination with medications known as psoralens (PUVA treatment). (thesshclinic.com)
  • The procedure takes approximately 2-3 hours to harvest the fat, which will then be processed before being re-injected into the breasts. (cranfordhouseplasticsurgery.com.au)
  • Traditional procedures involve the surgeon making a 3- to 5-inch incision to harvest bone from the patient's hip area, and some studies have shown that complications arise in nearly a third (31%) of these patients. (pr.com)