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  • Procedure
  • A procedure in which a patient receives healthy stem cells to replace their own cells destroyed by disease or high doses of anticancer drugs or by the radiation that are given as part of the procedure. (conferenceseries.com)
  • spinal cord i
  • Its beneficial influence is important for regeneration after trauma, for example, in spinal cord injury or Huntington's and Parkinson's diseases. (umdnj.edu)
  • Diseases such as stroke and spinal cord injury, myocardial infarction might possibly be treated with greater efficacy using cord blood stem cell therapy based approaches rather than current treatment options. (cordbloodcenter.com)
  • It is hoped and expected that, in the future, cord blood stem cells will be used to treat many other disorders, including Alzheimer's disease, diabetes , heart disease, liver disease, muscular dystrophy, Parkinson's disease (a neurological illness), spinal cord injury and stroke. (womenfitness.net)
  • Regenerative Medicine
  • The self-renewal and differentiation status of a stem cell is very important in the applications concerning regenerative medicine. (ebscohost.com)
  • The initial finding that pluripotency could be induced in human somatic cells revolutionized the field of regenerative medicine, since patient-specific stem cells can now be generated to further examine the causes and mechanisms of various human diseases. (sanguinebio.com)
  • therapies
  • This large share can primarily be attributed to the rising commercialization of allogeneic stem cell therapy products, wider therapeutic applications of allogeneic stem cells, easy production scale-up process, and growing number of clinical trials related to allogeneic stem cell therapies. (marketsandmarkets.com)
  • Cord blood is not just a ''bag of blood stem cells,'' and newer therapies are leveraging the activities of monocytes and other cells in the mix. (cryo-save.co.za)
  • While these results are preliminary, they create hope for cord blood-derived cellular therapies as novel treatments for diseases that cause life-long disabilities and currently have no curative options. (cryo-save.co.za)
  • Researchers at UC San Diego Moores Cancer Center have launched three clinical trials to test the safety and efficacy of a novel cellular-immunotherapy that uses modified T cells - one of the immune system's primary weapons - to treat three different types of blood cancer that often defy existing therapies. (cordbloodresearchnews.com)
  • Plasticell is a biotechnology company developing therapies through precise manipulation of stem cells and more differentiated cell types using award-winning combinatorial screening technology. (todayinscience.com)
  • disorders
  • There have been several allogeneic uses of CBE stem cells for leukemia and other cancers , as well as immune disorders. (howstuffworks.com)
  • Gene-therapy research involving modification of autologous cord blood stem cells for the treatment of childhood genetic disorders, although experimental at the present time, may prove to be of value. (aappublications.org)
  • Umbilical cord blood from public registers is used especially for treating leukemia in children and adults or genetic disorders of blood formation and metabolism in child patients. (cordbloodcenter.com)
  • The company s product portfolio includes allogeneic stem cell-based products for musculoskeletal disorders (such as Bio4) and wounds and injuries application (such as Grafix, Stravix, and TruSkin). (marketsandmarkets.com)
  • On the basis of therapeutic application, the global stem cell therapy market is segmented into musculoskeletal disorders, wounds and injuries, cardiovascular diseases, surgeries, gastrointestinal diseases, and other applications. (marketsandmarkets.com)
  • The musculoskeletal disorders segment is expected to command the largest share of the global stem cell therapy market in 2016. (marketsandmarkets.com)
  • This large share can be attributed to the rising availability of stem cell-based products for the treatment of musculoskeletal disorders, high prevalence of musculoskeletal disorders and bone & joint diseases, and growing patient preference for effective & early treatment strategies. (marketsandmarkets.com)
  • Our team performs blood and marrow transplants to treat a wide range of cancers and blood disorders. (carolinashealthcare.org)
  • graft
  • I. Estimate the incidence and severity of acute and chronic graft-versus-host disease (GVHD) in patients receiving Notch-expanded cord blood cells. (clinicaltrials.gov)
  • Determine the incidence of neutrophil engraftment, primary and secondary graft failure, platelet engraftment, and red blood cell engraftment in patients treated with this regimen. (clinicaltrials.gov)
  • The donated stem cells may replace the patient's immune cells and help destroy any remaining cancer cells (graft-versus-tumor effect). (clinicaltrials.gov)
  • Even in the mismatched setting, cord blood caused fewer incidences of graft-versus-host disease without losing leukaemia fighting activities. (cryo-save.co.za)
  • The results are excellent when the stem cell donor is a matched sibling: less than 5% mortality, 5-10% incidence of graft rejection, and close to 90% SCD-free survival. (smartcells.com)
  • Cord blood is readily available and is thought to be antigenically naive, thus hopefully minimizing the incidence of graft-versus-host disease (GVHD) and permitting the broader use of unrelated cord blood transplants. (docplayer.net)
  • clinical
  • Umbilical cord blood (UCB) has been shown to lessen the clinical and radiographic impact of hypoxic brain injury and stroke in animal models. (clinicaltrials.gov)
  • Presenting new technologies, specific case studies, updates on GMP, MHRA regulatory guidelines, quality control and therapeutic applications of stem cells, pre-clinical and clinical trial design, advanced cell engineering technologies, commercialisation of ATMPs, global pricing, ethical overviews and many more. (smi-online.co.uk)
  • Allogeneic (donated) cord blood stem cells recently became being used in clinical trials for medicine regenerative applications. (cordbloodcenter.com)
  • There is currently a clinical trial that is transplanting umbilical cord stem cells into the retina of those who have an advanced form of macular degeneration, called geographic atrophy. (enhancedvision.com)
  • Tracy is responsible for assessing, analyzing, and recommending quality and clinical performance improvement processes for the Sarah Cannon Blood Cancer Network and Sarah Cannon Research Institute. (factwebsite.org)
  • Sue established and managed a stem cell laboratory within the National Blood Service, providing clinical service to local London hospitals, including stem cell assays and cryopreservation. (factwebsite.org)
  • The use of stem cells of different origin, including autologous and allogeneic cord blood, which contains stem cells of various types, in experimental and clinical practice has demonstrated positive results. (org.ua)
  • Clinical use of umbilical cord blood in hypoxic-ischemic encephalopathy in newborns. (org.ua)
  • Dr. Dzhiun Lee (Singapore) and Dr. Dariusz Boruczkowski (Poland) also shared experience of clinical application of stem cells. (org.ua)
  • Factors such as growing awareness related to the therapeutic potency of stem cells, increasing number of clinical trials for stem cell-based products, and increasing public-private funding & research grants are driving the growth of this market. (marketsandmarkets.com)
  • And a clinical trial to see whether cord blood transplants improve symptoms of children with autism spectrum disorder should wrap up in the summer of 2018, says pediatric researcher and clinician Joanne Kurtzberg of Duke University, who helped establish a not-for-profit umbilical cord bank in North Carolina. (spiritofilithyia.com)
  • or if: an affected biological parent is enrolled in a clinical or research trial that would accept a haploidentical, related, allogeneic cord blood unit as a treatment option. (docplayer.net)