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Transplantation, AutologousBone Marrow TransplantationStem Cell TransplantationHematopoietic Stem Cell TransplantationBone Marrow CellsBone MarrowTransplantation, HomologousStem CellsHematopoietic Stem CellsTransplantation ConditioningBone Marrow PurgingPeripheral Blood Stem Cell TransplantationCombined Modality TherapyMesenchymal Stem Cell TransplantationHematopoietic Stem Cell MobilizationGraft SurvivalTreatment OutcomeCell DifferentiationWhole-Body IrradiationGraft vs Host DiseaseLiver TransplantationMelphalanCyclophosphamideGranulocyte Colony-Stimulating FactorLymphoma, Non-HodgkinCarmustineHematopoiesisMultiple MyelomaColony-Forming Units AssayAntigens, CD34Remission InductionAntineoplastic Combined Chemotherapy ProtocolsAdult Stem CellsTransplantation ChimeraCells, CulturedTime FactorsRecurrenceBusulfanHematologic NeoplasmsKidney TransplantationMice, Inbred C57BLMesenchymal Stromal CellsBone and BonesEtoposideCell TransplantationCell SeparationHodgkin DiseaseSalvage TherapyFlow CytometryRegenerationTissue DonorsSurvival AnalysisCytarabineLeukemia, Myeloid, AcuteDisease-Free SurvivalRetrospective StudiesLeukemiaRadiation ChimeraSurvival RateCell LineageCord Blood Stem Cell TransplantationHeart TransplantationMyeloablative AgonistsImmunosuppressive AgentsFollow-Up StudiesBone Marrow DiseasesLung TransplantationVincristineProto-Oncogene Proteins c-kitRecovery of FunctionCell SurvivalLiver RegenerationHistocompatibility TestingThiotepaNeovascularization, PhysiologicMyelodysplastic SyndromesTransplantation, IsogeneicT-LymphocytesLymphomaMultipotent Stem CellsTransplantation ImmunologyGraft RejectionDisease Models, AnimalPrognosisPrecursor Cell Lymphoblastic Leukemia-LymphomaAntigens, CDOrgan TransplantationHistocompatibilityEmbryonic Stem CellsHematologic DiseasesMyocardial InfarctionBlood Transfusion, AutologousLeukemia, MyeloidLeukapheresisGraft vs Tumor EffectNeoplasm, ResidualMice, TransgenicImmunosuppressionMice, Inbred BALB CCell Division
TransplantChemotherapyTransplantsASCTRemissionAllogeneic hematopoietic stem cClinicalFollicular lymphomaProgenitor cellsMesenchymalPatient's own bloodLymphomaDonorEfficacyMyelomaSurvivalMSCsTherapy2000ProcedureHSCTAdultPatientsImmunologyAplasticLymphoproliferative disordersDiffuseHaematologicalInfectionsProliferationUmbilicalCancersSpleenPeripheral Blood Stem CellCancerous cellsAspirationComplicationsTreatmentLymphImmuneMononuclearEmbryonic stemDifferentiationInfiltration
Transplant37
  • We present an unusual case of monomorphic T cell PTLD with features of angioimmunoblastic T cell lymphoma in an 8-year-old heart transplant patient, presenting with cranial nerve palsy. (karger.com)
  • Blaes AH, Morrison VA: Post-transplant lymphoproliferative disorders following solid-organ transplantation. (karger.com)
  • Morovic A, Jaffe ES, Raffeld M, Schrager JA: Metachronous EBV-associated B-cell and T-cell posttransplant lymphoproliferative disorders in a heart transplant recipient. (karger.com)
  • Lundell R, Elenitoba-Johnson KS, Lim MS: T-cell posttransplant lymphoproliferative disorder occurring in a pediatric solid-organ transplant patient. (karger.com)
  • Yang F, Li Y, Braylan R, Hunger SP, Yang LJ: Pediatric T-cell post-transplant lymphoproliferative disorder after solid organ transplantation. (karger.com)
  • Williams KM, Higman MA, Chen AR, Schwartz CL, Wharam M, Colombani P, Arceci RJ: Successful treatment of a child with late-onset T-cell post-transplant lymphoproliferative disorder/lymphoma. (karger.com)
  • note = "Funding Information: Acknowledgements The authors would like to thank all the physicians and data managers at each transplant center and the staff members of the Japanese Data Center for Hematopoietic Cell Transplantation. (elsevierpure.com)
  • High-risk patients do not benefit from stem cell transplant and should be offered alternative therapies. (elsevierpure.com)
  • Your child had a bone marrow transplant. (medlineplus.gov)
  • Tell your child's dentist that your child has had a bone marrow transplant. (medlineplus.gov)
  • When considering a bone marrow transplant in Durban, exploring different hospitals and doctors to find the right treatment and care for your specific needs is important. (yapitahealth.com)
  • What is a bone marrow transplant? (yapitahealth.com)
  • In bone marrow transplant or stem cell transplant, healthy blood-forming stem cells replace damaged bone marrow that cannot produce enough healthy blood cells. (yapitahealth.com)
  • Why would someone need to have a bone marrow transplant? (yapitahealth.com)
  • Bone marrow transplant is recommended when bone marrow lacks stem cell production. (yapitahealth.com)
  • What conditions can a bone marrow transplant treat? (yapitahealth.com)
  • Patients are explained thoroughly regarding Bone marrow transplant including the evaluation process, treatment side effects, cost of treatment, and associated complications. (yapitahealth.com)
  • Finding accommodation in a hotel because patients for autologous transplants need to stay for 30 days locally and allogenic transplant patients need to stay for 100 days. (yapitahealth.com)
  • In autologous transplant- the patient's own stem cells are collected and stored before conditioning. (yapitahealth.com)
  • Data have been limited to this point, prompting us to take a closer look at this issue in a larger, more diverse group of autologous and allogeneic transplant survivors over an extended period. (science20.com)
  • Participants completed two questionnaires that together evaluated specific areas of sexual function (sexual cognition/fantasy, sexual arousal, sexual behavior/experience, orgasm, and drive/relationship) as well as sexual satisfaction at a median time of 17 days pre-transplant and at six, 12, 24, and 36 months post-transplant. (science20.com)
  • During the three-year post-transplant analysis period, the percentage of men who self-reported being "sexually active" (defined as having sex with a partner at least once in the preceding month) declined 7 percentage points, with 61 percent of men reporting sexual activity pre-transplant and 54 percent reporting activity post-transplant. (science20.com)
  • Any organ transplant program with lower-than-expected outcomes for respective 1-month and 1-year periods will be subject to a participation warning. (humana.com)
  • Programs that perform fewer than 35 annual autologous or 35 annual allogeneic transplants will be required to submit data from the immediately preceding year's transplants in order to obtain a statistically significant number of transplant cases (35). (humana.com)
  • Arvin AM . Varicella-zoster virus: pathogenesis, immunity, and clinical management in hematopoietic cell transplant recipients. (nature.com)
  • This is the 35th transplant case to be discharged from the hospital and singnifies the anniversary of 35th successful autologous stem cell transplants in children. (baothuathienhue.vn)
  • The patient having bone marrow transplant is Phan D. D., 4 years old, from Dac Lac province. (baothuathienhue.vn)
  • After the course of treatment, he had a partial response and was indicated for a bone marrow transplant. (baothuathienhue.vn)
  • After more than 3 years, the Pediatric Center performed stem cell transplant for 35 cases (31 cases of high-risk neuroblastoma, 2 cases of metastatic retinoblastoma and 2 cases of recurrent non-Hodgkin lymphoma). (baothuathienhue.vn)
  • Hue Central Hospital is equipped with modern machinery and instruments, and an international standard stem cell transplant room. (baothuathienhue.vn)
  • What is an autologous stem cell transplant? (leukaemia.org.au)
  • Most people have a single autologous transplant. (leukaemia.org.au)
  • It's important to realise that the processes involved in a stem cell transplant are often long and complex. (leukaemia.org.au)
  • Forty-two female patients (median age of 46 years) with breast cancer refractory to neoadjuvant chemotherapy received HDCT (cyclophosphamide, carmustine and thiotepa) supported by an autologous peripheral blood stem cells transplant. (elsevierpure.com)
  • Hopefully, following the recommendations made in the guidelines will reduce morbidity and mortality from opportunistic infections in hematopoietic stem cell transplant recipients. (cdc.gov)
  • For the purposes of this document, HSCT is defined of the CDC, the Infectious Diseases Society of America, as any transplantation of blood or marrow-derived he- and the American Society of Blood and Marrow Trans- matopoietic stem cells, regardless of transplant type plantation," which was published in the Morbidity and (allogeneic or autologous) or cell source (bone marrow, Mortality Weekly Report [1]. (cdc.gov)
  • 202. Autologous stem cell transplant within 6 weeks of planned KTE-X19 or axicabtagene ciloleucel infusion. (who.int)
Chemotherapy30
  • Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma. (smw.ch)
  • High-dose therapy and autologous bone marrow transplantation after failure of conventional chemotherapy in adults with intermediate-grade or high-grade non-Hodgkin's lymphoma. (smw.ch)
  • High-dose sequential chemotherapy followed by autologous stem cell transplantation in relapsed and refractory aggressive non-Hodgkin's lymphoma: results of a multicenter phase II study. (smw.ch)
  • High dose sequential chemotherapy and autologous stem cell transplantation in patients with relapsed/refractory lymphoma. (smw.ch)
  • The role of intensive therapy and autologous blood and marrow transplantation for chemotherapy-sensitive relapsed and primary refractory non-Hodgkin's lymphoma: identification of major prognostic groups. (smw.ch)
  • High-dose chemotherapy with autologous bone marrow transplantation: 11 years' experience in Zurich. (smw.ch)
  • At 1 and 6 months after completion of chemotherapy, she presented with anasarca and was diagnosed with relapse exclusively in the bone marrow twice. (karger.com)
  • Consequently, we proceeded with salvage chemotherapy followed by autologous stem cell transplantation. (karger.com)
  • [ 2 ] Options for second-line therapy in patients with relapsed/refractory disease include chemotherapy-free regimens with biologic targeted agents such as covalent Bruton tyrosine kinase (BTK) inhibitors, lenalidomide,venetoclax, and chimeric antigen receptor (CAR) T-cell therapy. (medscape.com)
  • 5 Combining rituximab, a monoclonal antibody targeting the CD20 antigen on B cells, with standard chemotherapy has improved NHL treatment outcomes. (haematologica.org)
  • In the present study, the case of a patient diagnosed with diffuse large B‑cell lymphoma, who received chemotherapy and autologous hematopoietic stem cell transplantation is presented. (spandidos-publications.com)
  • He was treated with chemotherapy (8 R-CHOP protocols) with partial response, followed by high-dose chemotherapy and autologous hematopoietic stem cell transplantation, with a complete response, and was stable for the previous 4 years. (spandidos-publications.com)
  • For example, people who have stem cell transplantation go through intensive chemotherapy before treatment. (clevelandclinic.org)
  • RATIONALE: Drugs used in chemotherapy, such as idarubicin and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. (stanford.edu)
  • Miyazaki K, Masuya M, Yamaguchi M, Isaka S, Nakase K, Kobayashi T, Nakamura S, Shiku H: Angioimmunoblastic T-cell lymphoma occurring four months after autologous peripheral blood stem cell transplantation with high-dose chemotherapy for follicular lymphoma. (karger.com)
  • They then injected the patients with their own immune stem cells, obtained from the patients' blood before the chemotherapy, to create a new immune system. (scienceblog.com)
  • We focus on destroying only the immune component of the bone marrow and then regenerate the immune component, which makes the procedure much safer and less toxic than traditional chemotherapy for cancer," Burt said. (scienceblog.com)
  • Autologous HSCT following high-dose chemotherapy, the standard treatment for adult patients with relapsed HL, is also effective in paediatric patients, but randomized trials showing its superiority to conventional therapy are lacking. (nih.gov)
  • Conditioning Process: Chemotherapy, radiotherapy or both are carried out before BMT to eliminate cancer or diseased cells. (yapitahealth.com)
  • Then the doctors will deal with the Myeloma and give me a different type of chemotherapy for another 2 months. (munirapremji.com)
  • Stem cells from my own bone marrow and in my blood will be extracted, frozen, stored and, after a high-dose chemotherapy treatment (where all good and bad cells in my bone marrow will be destroyed), will be infused back into me. (munirapremji.com)
  • Varicella zoster virus infection associated with high-dose chemotherapy and autologous stem-cell rescue. (nature.com)
  • They are used to replace stem cells that have been damaged by high doses of chemotherapy , used to treat the patient's underlying disease. (leukaemia.org.au)
  • Autologous transplants allow the use of high-dose chemotherapy, which provides some patients with a better chance of cure or long-term control of their disease. (leukaemia.org.au)
  • This process is called stem cell mobilisation and usually involves the use of chemotherapy in combination with colony stimulating growth factor injections - usually G-CSF. (leukaemia.org.au)
  • Purpose: To determine the tolerability and feasibility of double-cycle, high-dose chemotherapy followed by peripheral blood stem-cell transplantation (PBSCT) after conventional chemotherapy or chemoradiotherapy for small cell lung cancer (SCLC). (the-medical-dictionary.com)
  • Combination chemotherapy with cisplatin and etoposide (cisplatin-etoposide [PE]) has long been the mainstay of treatment for small cell lung cancer (SCLC). (the-medical-dictionary.com)
  • Further, cancer treatment often involves radiotherapy and chemotherapy, which not only kills cancer cells but also affects healthy cells. (aspetjournals.org)
  • Hematopoietic stem cell transplantation is also sometimes used for solid tumors (eg, some germ cell tumors) that respond to chemotherapy. (msdmanuals.com)
  • Opportunistic infections (OIs) are defined as any in- the infusion of hematopoietic stem cells from a donor fections that occur with increased frequency or severity into a patient who has received chemotherapy, which in HSCT patients. (cdc.gov)
Transplants8
  • 0.001).DiscussionThe use of AHSCT in people with active SPMS is associated with a slowing of disability progression and a higher likelihood of disability improvement compared with standard immunotherapy.Classification of EvidenceThis study provides Class III evidence that autologous hematopoietic stem cell transplants prolonged the time to CDP compared with other DMTs. (mssm.edu)
  • Overall, Durban offers a range of specialized hospitals and experienced medical professionals for bone marrow transplants, making it a viable option for individuals seeking this procedure. (yapitahealth.com)
  • Blood and bone marrow transplants have been done for decades and have always had risks of complications, like virtually any treatment for serious diseases, but a new study has found an additional one for the list: sexual health. (science20.com)
  • among them, the first cases of autologous stem cell transplants in Vietnam were performed in Hue, which were for patients with metastatic retinoblastoma and recurrent Burkitt Lymphoma. (baothuathienhue.vn)
  • In autologous stem cell transplants, the patient is their own stem cell donor. (leukaemia.org.au)
  • Autologous transplants are used to treat a number of different blood cancers. (leukaemia.org.au)
  • Others, particularly those with myeloma or some solid tumours, may have two or more sequential (one after the other) transplants, over a period of a few months. (leukaemia.org.au)
  • The idea to use transplants of dopa- ment of protocols that allow generation of fully functional mine-producing cells to substitute for the lost midbrain and safe midbrain dopamine neurons from stem cells. (lu.se)
ASCT6
  • OBJECTIVE: To assess the prognostic value of various parameters including positron emission tomography / computed tomography (PET/CT) and identify risk factors for survival of patients with non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL) treated with autologous stem cell transplantation (ASCT). (smw.ch)
  • High-dose melphalan and autologous stem cell transplantation (HDM/ASCT) is widely used in immunoglobulin light chain (AL) amyloidosis, but the benefit is debated mainly because of the high treatment-related mortality (24% in a randomised study comparing HDM/ASCT with oral melphalan/dexamethasone). (lu.se)
  • Treatment selection takes into account patient age, fitness, and whether autologous stem cell transplantation (ASCT) is planned. (medscape.com)
  • The occurrence of varicella zoster virus (VZV) reactivation is increased after allogeneic transplantation, whereas limited data are available for herpes zoster (HZ) after autologous SCT (ASCT). (nature.com)
  • We found that VZV reactivation occurred in 57 (30%) patients, in 8.5% during induction and in 21.5% after ASCT peaking at 8 months after ASCT. (nature.com)
  • Lower specific antibody titers at transplantation were observed in patients with HZ after ASCT than in those without reactivation ( P =0.009). (nature.com)
Remission6
  • Complete remission was achieved in 84% of dogs for a median of about 9 months. (vin.com)
  • People in remission from AML may be candidates for allogeneic stem cell transplantation. (clevelandclinic.org)
  • ADDITIONAL BACKGROUND: S0919 was initially designed for patients with relapsed acute myeloid leukemia (AML), where the patient's preceding remission had lasted ≥ 3 months. (stanford.edu)
  • They must have achieved complete remission (CR), lasting at least three months with their last induction regimen and they must have relapsed after the last regimen. (stanford.edu)
  • These cells are collected in advance (while they are in remission ) and returned to the patient at a later stage. (leukaemia.org.au)
  • Stem cells are usually collected when the patient's disease is in remission or their disease is in a more stable state. (leukaemia.org.au)
Allogeneic hematopoietic stem c2
Clinical19
  • Low-dose filgrastim significantly enhances neutrophil recovery following autologous peripheral-blood stem-cell transplantation in patients with lymphoproliferative disorders: evidence for clinical and economic benefit. (smw.ch)
  • To our knowledge, this is the first reported case of primary pituitary lymphoma that relapsed exclusively in the bone marrow and presented with clinical findings of idiopathic anasarca. (karger.com)
  • All he has to do is succeed in his ongoing clinical trials using cell therapy in congestive heart failure. (cellmedicine.com)
  • The U.S. Food and Drug Administration (FDA) has made Amit the only individual in the entire nation to gain its endorsement to undertake clinical trials for treating heart patients by directly injecting adult stem cells into the heart. (cellmedicine.com)
  • The clinical trial for 'Autologous Bone Marrow Progenitor Cell Treatment for Heart Failure,' at the University of Pittsburgh Medical Center is lead by Dr. Amit. (cellmedicine.com)
  • Clinical manifestations include bone pain, renal impairment, recurrent infections and anaemia. (bmj.com)
  • Preclinical and some small-scaled clinical trials have suggested feasibility and safety of cardiac stem cell therapy. (escardio.org)
  • Cell therapy is currently emerging as a potential new treatment for post MI patients with the assumption that recolonization of the areas of scarred myocardium with exogenously supplied surrogates or precursors of cardiomyocytes can restore function and ultimately affect clinical outcomes. (escardio.org)
  • Various cell types have been tested experimentally for cardiac repair so far, but only those of autologous origin have yet undergone clinical testing due to immune competency. (escardio.org)
  • In experimental and clinical studies unselected mononuclear bone marrow cells as well as specific subpopulations have been used for transplantation. (escardio.org)
  • Genetic aberrations have emerged as major prognostic factors for patients with multiple myeloma (MM). We evaluated 126 MM patients for t(4;14) or t(11;14), 13q or p53 deletions and correlated the number of genetic aberrations with patient's clinical outcome following undergoing autologous stem cell transplantation. (elsevierpure.com)
  • The extension of bone marrow and extramedullary involvement should be carefully evaluated to establish prognosis and clinical management [ 4 ]. (hindawi.com)
  • This success opens the door to a phase II clinical trial that can test the efficacy of autologous bone marrow SCs. (parentsguidecordblood.org)
  • National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines also recommend the use of serum free light chain assay and plasma cell fluorescence in situ hybridization (FISH) on bone marrow: del 13, del 17p13, t(4;14), t(11;14), t(14;16), t(14;20), 1q21 amplification, 1p deletion as part of the initial diagnostic workup. (medscape.com)
  • Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. (lookformedical.com)
  • Varicella zoster virus infections following allogeneic bone marrow transplantation: frequency, risk factors, and clinical outcome. (nature.com)
  • Also, the multidisciplinary coordination exercise needed to develop this clinical trial protocol will undoubtfully be useful to conduct academic clinical trials in the field of cell therapy in the near future. (unav.edu)
  • Methods: A phase I multicentre clinical trial (ClinicalTrials.gov NCT01919827) with a single endobronchial administration of autologous adult BM-MSCs in patients diagnosed with mild-to-moderate IPF. (unav.edu)
  • The clinical manifestations of Waldenström macroglobulinemia result from the presence of the IgM paraprotein and malignant lymphoplasmacytic cell infiltration of the bone marrow and other tissue sites. (medscape.com)
Follicular lymphoma4
Progenitor cells5
  • The bone morrow contains several stem cell types including hematopoetic stem cells, endothelial progenitor cells, mesenchymal (stromal) stem cells and multipotent adult progenitor cells. (escardio.org)
  • Although there is no definitive evidence, combinations of progenitor cells seem to be more benefical than specific stem cell type for cardiac repair (3). (escardio.org)
  • Interestingly, contradictory data exist for transformation of bone marrow derived progenitor cells (BMPC) into new cardiomyocytes and alternative mechanisms as enhanced neovascularization, enhanced scar tissue formation due to augmented inflammatory response and decreased apoptosis have been suggested for the benefical effects of these cells on myocardial function after myocardial infarction (4). (escardio.org)
  • This article contains highlights of "Guidelines for Pre- allogeneic or autologous, depending on the source of venting Opportunistic Infections among Hematopoi- the transplanted hematopoietic progenitor cells. (cdc.gov)
  • The allogeneic HSCT was the most frequently performed (57.14%) and the most used source of Hematopoietic progenitor cells (HPC) was the peripheral blood (54.29%) and 5.71% of these patients developed the Graft versus Host Disease (GVHD), of which one was affected by acute GVHD and another by chronic GVHD. (bvsalud.org)
Mesenchymal11
  • While the origin of these tumors is still not definitively known, the two theories with the most support suggest that these tumors arise from a primitive cell derived either from an embryologic tissue called the neural crest, or from resident cells in the body (called mesenchymal stem cells) that have a capability to become one of a variety of tissue types. (sarcomahelp.org)
  • We have isolated a cardiomyogenic cell line (CMG cell) from murine bone marrow mesenchymal stem cells. (elsevierpure.com)
  • Fukuda, K 2002, ' Reprogramming of bone marrow mesenchymal stem cells into cardiomyocytes ', Comptes Rendus - Biologies , vol. 325, no. 10, pp. 1027-1038. (elsevierpure.com)
  • Mesenchymal stem cells (MSCs) can differentiate into chondrocytes, while mechanical loading has been proposed as alternative strategy to induce chondrogenesis excluding the use of exogenous factors. (nature.com)
  • Accordingly, investigations on cellular therapies have therefore moved to progenitor cell populations such as bone marrow derived mesenchymal stem cells (BMSCs), which have the ability to differentiate into cartilage cells 4 . (nature.com)
  • These studies have demonstrated that mechanical forces are able to shape the mesenchymal stem cell (MSC) fate when appropriately applied in in vitro models of cartilage regeneration. (nature.com)
  • Both in animal models and humans, it has been shown that cell therapy can induce therapeutic angiogenesis, making mesenchymal stromal cell-based therapy one of the most promising therapeutic alternatives. (unav.edu)
  • The aim of this study is to evaluate the feasibility, safety, and efficacy of cell therapy based on mesenchymal stromal cells derived from adipose tissue intramuscular administration to patients with type 2 diabetes mellitus with critical limb ischemia and without possibility of revascularization. (unav.edu)
  • Mesenchymal stromal cells (MSCs) have shown benefit in other inflammatory diseases. (unav.edu)
  • DOI:10.1371journal.pone.0113936 December 1,2 Mesenchymal Stem Cells in MSMSCs or equivalent volume of suspension media at baseline. (ephb4inhibitor.com)
  • Mesenchymal stem cells (MSCs) are ASCs, and were first described in 1966 by Friedenstein et al. (bvsalud.org)
Patient's own blood2
Lymphoma27
  • Of the NHL patients, 59 (44%) had diffuse large B-cell lymphoma (DLBCL). (smw.ch)
  • Anaplastic large-cell lymphoma (ALCL) refers to a group of non-Hodgkin lymphomas in which aberrant T cells proliferate uncontrollably. (wikipedia.org)
  • These tissues have lymphoma-like infiltrates that have variable numbers of ALCL "hallmark" cells, i.e. cells with kidney- or horseshoe-shaped nuclei that strongly express CD30 as detected by immunohistochemistry and an ALK fusion protein as detected by fluorescence in situ hybridization. (wikipedia.org)
  • We report a case of primary large B cell-type pituitary lymphoma in a 47-year-old immunocompetent female who presented with headache and cranial nerve palsy. (karger.com)
  • Liu JK, Sayama C, Chin SS, Couldwell WT: Extranodal NK/T-cell lymphoma presenting as a pituitary mass. (karger.com)
  • Aho R, Ecfor T: Pathogenesis of primary central nervous lymphoma: invasion of malignant lymphoid cells into and within the brain parenchyma. (karger.com)
  • Fleming WH, Murphy PR, Murphy LJ, Hatton TW, Matusik RJ, Friesen NG: Human growth hormone induces and maintains cmyc gene expression in Nb2 lymphoma cells. (karger.com)
  • Mantle cell lymphoma (MCL) is a lymphoproliferative disorder derived from a subset of naive pregerminal center cells localized in primary follicles or in the mantle region of secondary follicles. (medscape.com)
  • Mantle cell lymphoma (MCL) is recognized in the Revised European-American Lymphoma and World Health Organization classifications as a distinct clinicopathologic entity. (medscape.com)
  • it was frequently categorized as diffuse small-cleaved cell lymphoma (by the International Working Formulation) or centrocytic lymphoma (by the Kiel classification). (medscape.com)
  • two patients (one each with diffuse large B-cell lymphoma and mantle cell lymphoma) achieved a complete response. (haematologica.org)
  • For the gene family, see B-cell CLL/lymphoma . (wikipedia.org)
  • [9] If enlarged lymph nodes are caused by infiltrating CLL-type cells, a diagnosis of small lymphocytic lymphoma (SLL) is made. (wikipedia.org)
  • Untreated lymphoma progresses rapidly (1-2 months) from presentation to terminal stages. (vin.com)
  • Although children, adolescents, and young adults with newly diagnosed B-cell non-Hodgkin's lymphoma enjoy excellent overall survival with current chemoimmunotherapy, those with relapsed and/or refractory disease have a dismal prognosis. (jnccn.org)
  • Children, adolescents, and young adults (CAYAs) with newly diagnosed B-cell non-Hodgkin's lymphoma (B-NHL) enjoy excellent overall survival (OS) with current frontline chemoimmunotherapy. (jnccn.org)
  • Kaplan-Meier curve showing probability of overall survival in children and adolescents with mature B-cell non‐Hodgkin's lymphoma with refractory or relapsed disease during or after therapy in the FAB/LMB96 international study. (jnccn.org)
  • Overall survival of children and adolescents with mature B cell non-Hodgkin lymphoma who had refractory or relapsed disease during or after treatment with FAB/LMB 96: a report from the FAB/LMB 96 study group. (jnccn.org)
  • de Leval L, Gisselbrecht C, Gaulard P: Advances in the understanding and management of angioimmunoblastic T-cell lymphoma. (karger.com)
  • Data suggest that young patients with recurring disease following autologous HSCT, as well as some patients with multiple relapses and selected patients with refractory lymphoma, might benefit from allogeneic HSCT, but relapse remains the major challenge. (nih.gov)
  • Bone marrow transplantation is a complex yet life-saving procedure that can benefit individuals with a wide range of diseases, including blood cancers like leukemia and lymphoma, aplastic anemia, immune deficiencies, and genetic disorders. (yapitahealth.com)
  • Stem cell transplantation is an increasingly effective form of treatment for patients with blood cancer such as leukemia, lymphoma, and myeloma. (science20.com)
  • Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. (lookformedical.com)
  • Myeloproliferative disorders (MPD) with eosinophilia (or chronic eosinophilic leukemia (CEL) and sporadic cases with acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia (ALL) or lymphoma. (atlasgeneticsoncology.org)
  • 2015), 1 mantle cell lymphoma (MCL) (Le Baccon et al. (atlasgeneticsoncology.org)
  • 2001) and 1 diffuse large B-cell lymphoma (DLBCL) (Le Baccon et al. (atlasgeneticsoncology.org)
  • Hue Central Hospital Pediatric Center has implemented autologous stem cell transplantation for patients with solid tumors and lymphoma since November 2019. (baothuathienhue.vn)
Donor8
  • Strikingly, 12 cases occurred in 1997 with the majority in recipients of allogeneic matched sibling donor stem cells. (nih.gov)
  • Allogeneic stem cell transplantation uses donor stem cells to treat and sometimes cure certain blood disorders and blood cancers. (clevelandclinic.org)
  • While both treatments help your bone marrow to develop new blood cells, studies show allogeneic stem cell transplantations work by causing the donor cells to attack unhealthy cells. (clevelandclinic.org)
  • The authors confirm chronic graft-versus-host disease (GVHD), a serious complication that occurs when donor cells attack the recipient's cells, as a potential source of sexual dysfunction and say they are the first to demonstrate an association between total body irradiation and sexual dysfunction in men. (science20.com)
  • eg, bone, bone marrow, and skin grafts) Genetically identical (syngeneic [between monozygotic twins]) donor tissue (isografts) Genetically. (msdmanuals.com)
  • Hematopoietic stem cell transplantation may be autologous (using the patient's own cells) or allogeneic (using cells from a donor). (msdmanuals.com)
  • Although previous recommendations for preventing transmission of human immunodeficiency virus (HIV) through transplantation of human tissue and organs have markedly reduced the risk for this type of transmission, a case of HIV transmission from a screened, antibody-negative donor to several recipients raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
  • the donor.4,11 In the case of nerve cells obtained from either delivery of dopamine released from cells the developing central nervous system (CNS), the opti- implanted into the ventricle, adjacent to the stria- mal age was shown to be at, or close to, the cell-cycle tum,6,7 or restoration of synaptic dopamine release exit. (lu.se)
Efficacy3
  • To determine the safety and efficacy of intramyocardial autologous blood stem cell injection for cardiomyopathy. (tci-thaijo.org)
  • Ruengsakulrach P, Visudharom K, Chaothawee L, Belkin M. Safety and Efficacy of Intramyocardial Implantation of Peripheral Blood Stem Cell for Cardiomyopathy. (tci-thaijo.org)
  • Understanding the molecular mechanisms governing mIBG transport in cancer and normal cells is a critical step for developing strategies to optimize the efficacy of 131 I-mIBG while minimizing toxicity in normal tissues. (aspetjournals.org)
Myeloma10
  • Validation of prognostic factors and survival of patients with multiple myeloma in a real-life autologous stem cell transplantation setting: a Swiss single centre experience. (smw.ch)
  • Myeloma is a B-cell malignancy that is characterised by the monoclonal expansion and accumulation of abnormal plasma cells within the bone marrow. (bmj.com)
  • Within 15 months, the patient had rapidly progressed to ISS stage 3 myeloma with M-protein 49 g/L, urinary protein 1.3 g/24-hour, Bence-Jones protein 1.0 g/24-hour, Hb 9.7 g/dL and increasing back pain. (bmj.com)
  • This was the first example of a successful SC therapy, and is still commonly used today for blood and bone-marrow-related cancers such as leukemia and myeloma. (parentsguidecordblood.org)
  • Multiple myeloma (MM) is a plasma cell malignancy in which monoclonal plasma cells proliferate in bone marrow, resulting in an overabundance of monoclonal paraprotein (M protein), destruction of bone, and displacement of other hematopoietic cell lines. (medscape.com)
  • Bone marrow aspirate demonstrating plasma cells of multiple myeloma. (medscape.com)
  • For the Myeloma, the plan is to do what is known as an Autologous stem cell transplantation. (munirapremji.com)
  • The same words also underpin this year's Myeloma Action Month (MAM) , which is the same month that EBMT's 48th Annual Meeting takes place. (janssen.com)
  • ABSTRACT Multiple myeloma (MM) is a systemic malignancy of pathologic plasma cells that is treat able with chemotherapeutic agents and irradiation, but rarely curable. (who.int)
  • Multiple myeloma (MM) is a cancer of the The largest series, 23 patients with lepto- plasma cells. (who.int)
Survival11
  • Activations of these signaling pathways and genes may stimulate cell growth, proliferation, survival, and/or other behaviors that promote malignancy. (wikipedia.org)
  • In patients with cardiac involvement or multiple organ involvement, survival was significantly shorter, median overall survival 49 and 56 months, respectively. (lu.se)
  • Cell therapy is a potential new treatment for post MI patients, but the main challenges are : the necessity to preserve immune competency and to gain adequate nutrition and homing signals necessary for stem cells' engraftment and survival. (escardio.org)
  • Repair of scar tissue constitutes a challenge for cardiac stem cell therapy due to lack of adequate nutrition and homing signals necessary for stem cells' engraftment and survival. (escardio.org)
  • Although most clinicians would agree that hematopoietic progenitor cell transplantation after reinduction therapy is frontline therapy for these patients, there is no consensus as to what type of hematopoietic progenitor cell transplantation promises the best event-free and overall survival. (jnccn.org)
  • According to patient selection criteria, overall and disease-free survival rates after autologous HSCT are 43-95% and 31-70%, respectively. (nih.gov)
  • As blood or bone marrow transplantation survival rates have steadily increased, researchers are seeking to study and maximize survivors' quality of life. (science20.com)
  • American Society for Blood and Marrow Transplantation (ASBMT) statistics/forms (including the 100-day survival statistics) must be received by NTN no later than Oct. 1 of each calendar year. (humana.com)
  • Response rates in extensive disease (ED) range from 51 to 78%, including a 7 to 13% rate of complete response (CR) and a median survival of 8 to 9 months. (the-medical-dictionary.com)
  • In patients with limited disease (LD), the CR rate is 16 to 18%, with a median survival of 11.7 to 12.4 months. (the-medical-dictionary.com)
  • Hematopoietic stem cell transplantation not responded to other therapeutic modalities, with (HSCT) is used in children as a definitive treatment an increase in survival after transplantation, for different oncological, immune deficiencies, contributing to its use (YEILIPEK, 2014). (bvsalud.org)
MSCs3
  • Objectives: To evaluate the safety and feasibility of endobronchial administration of bone marrow autologous MSCs (BM-MSC) in patients with mild-to-moderate IPF. (unav.edu)
  • At 6 months since the 1st infusion, remedy was reversed (i.e., sufferers who received initial suspension media received cryopreserved MSCs and vice versa). (ephb4inhibitor.com)
  • MSCs can be isolated from different locations, such as bone marrow, umbilical cord, placenta, adipose and dental tissues. (bvsalud.org)
Therapy23
  • The place of high-dose BEAM therapy and autologous bone marrow transplantation in poor-risk Hodgkin's disease. (smw.ch)
  • He is the director of the Center for Cardiac Cell Therapy at the university. (cellmedicine.com)
  • Prognostic factors include stage and substage of disease, histologic type, immunophenotype (B-cell versus T-cell), presence of hypercalcemia, response to therapy, pre-treatment steroid therapy, and possibly gender. (vin.com)
  • Although there was evidence of a response to CTD (M-protein 34 g/L), bortezomib and dexamethasone treatment was initiated as an alternative, but this was discontinued after three cycles due to progressive disease (M-protein 49 g/L). The patient was then treated with lenalidomide and dexamethasone with the aim of reducing disease burden prior to high-dose therapy and autologous stem cell transplantation. (bmj.com)
  • As such, stem cell therapy cannot be regarded as a valid therapeutic option for patients with cardiovascular disease in the present era of evidenced-based medicine, yet it holds great hope for the future. (escardio.org)
  • This review outlines the disparate types of stem cell therapy that have been used in this difficult-to-treat population as well as the role of maintenance and CAR T-cell therapy in conjunction with stem cell therapy. (jnccn.org)
  • 1 - 3 However, those with relapsed and/or refractory (R/R) disease have had a historically dismal OS of ≤30% despite reinduction therapy and autologous hematopoietic progenitor cell transplantation (autoHCT) ( Figure 1 ). (jnccn.org)
  • HCT, whether it be autologous, allogeneic, or tandem, has been and continues to be an integral part of therapy, with varying outcomes as delineated in Table 2 . (jnccn.org)
  • and the role of CAR T-cell therapy as it relates to HCT as therapies for R/R B-NHL. (jnccn.org)
  • He observed that this highly aggressive bone cancer was remarkably sensitive to radiation therapy. (sarcomahelp.org)
  • One area where cell therapy has generated hope is neurology. (parentsguidecordblood.org)
  • Cell therapy protocols for cerebral palsy are an example of a new approach to a condition that is difficult to treat. (parentsguidecordblood.org)
  • Salvage therapy options include further chemo-radiotherapy and autologous or allogeneic haematopoietic SCT (HSCT). (nih.gov)
  • 12 months after completion of therapy) may be cured with conventional therapy, those with progressive disease or early relapse (3-12 months) are considered candidates for autologous HSCT. (nih.gov)
  • These findings indicated that cell transplantation therapy for the patients with heart failure might possibly be achieved using the regenerated cardiomyocytes from autologous bone marrow cells in the near future. (elsevierpure.com)
  • Currently, the only FDA-approved cell-based therapy for cartilage defects involves autologous chondrocyte implantation: chondrocytes harvested from low-contact areas are expanded in vitro and then re-injected directly into the damaged site 1 . (nature.com)
  • Conditioning therapy is used to help destroy any leftover cancer cells in your body and to make or create a space in your bone marrow for the new stem cells to grow. (leukaemia.org.au)
  • Sufferers were excluded if they had any active or chronic infection, treatment with any immunosuppressive therapy inside the earlier 3 months or interferon-beta, glatiramer acetate or corticosteroids within 30 days before randomization. (ephb4inhibitor.com)
  • The best response after surgery, HDCT, and radiation therapy was assessed 60 days after transplantation. (elsevierpure.com)
  • HSCT patients are presumed immunocompetent if they are at least 24 months post-HSCT, are not receiving immunosuppressive therapy, and do not have graft- versus-host disease (GVHD). (cdc.gov)
  • 205. Prior chimeric antigen receptor therapy or other genetically modified T cell therapy 206. (who.int)
  • Thus, evaluation of the plasma cell compartment in the bone marrow at baseline and after therapy may be helpful. (medscape.com)
  • Cell Therapy for Parkinsons Disease: What Next? (lu.se)
20001
  • Malignant plasma cells in meningeal MM out of 2000 patients with bone marrow produce an immunoglobulin, MM, was reported was by Schluterman et al. (who.int)
Procedure8
  • The patients in the small phase I/II trial continued to improve for up to 24 months after the transplantation procedure and then stabilized. (scienceblog.com)
  • The procedure is called autologous non-myeloablative haematopoietic stem-cell transplantion. (scienceblog.com)
  • The patients enrolled in our trial received a subcutaneous medication for 4 consecutive days to stimulate their bone marrow to produce SCs, their bone marrow was then harvested, SCs were concentrated at the laboratory, and then they were delivered through the patient's cerebrospinal fluid on the fifth day of the procedure. (parentsguidecordblood.org)
  • Even with this small group, less than 20 patients seen over 36 months, we were able to reach our goal, which was to demonstrate the safety of the procedure. (parentsguidecordblood.org)
  • The procedure involves replacing the damaged or diseased bone marrow with healthy blood-forming stem cells. (yapitahealth.com)
  • Central Line/Catheter Placement: This is an outpatient procedure that facilitates the infusion of cells, blood products, and IV medicines. (yapitahealth.com)
  • One concern about the procedure is that immune cells in cord blood do not have experience with the viruses responsible for latent infections, leading to a higher percentage of naive T cells and thus increased vulnerability to reactivation of cytomegalovirus or Epstein-Barr virus infection. (msdmanuals.com)
  • Two died while receiving high-dose systemic corticosteroids, methotrexate, and after recent exposure to anti-tumor necrosis factor-α biological DMARDs, and 2 during hematopoietic stem cell transplantation procedure. (cdc.gov)
HSCT5
  • Short time to relapse and refractory disease at the time of autologous HSCT remain the most important risk factors. (nih.gov)
  • There pediatric and adult autologous and allogeneic HSCT patients. (cdc.gov)
  • are basically 3 phases of immune recovery for HSCT patients, The purposes of the guidelines are (1) to summarize the beginning at day 0, the day of transplantation. (cdc.gov)
  • The Hematopoietic stem cell transplantation (HSCT) is used in children as a definitive treatment for various oncological, immune deficiencies, hemoglobinopathy, and malignancies diseases that involve the hematological system, congenital metabolism disorders, among others. (bvsalud.org)
  • This is a quantitative, retrospective, observational, descriptive and analytical quantitative approach approaching the medical records of children and adolescents submitted to HSCT in a referral hospital service for this type of transplantation in the state of Rio Grande do Sul North (RN). (bvsalud.org)
Adult5
Patients25
  • Most patients, including up to 90% of young children and adolescents, have circulating autoantibodies directed against the ALK fusion protein expressed by their tumor cells. (wikipedia.org)
  • Six patients are alive with a median follow-up of 18 months (range 12-60). (nih.gov)
  • Patients on stable doses of medications for past 3 months were recruited. (drcalapai.com)
  • Our observations indicate that SCT is a safe and effective modality of results to improve β-cell function in patients with T2DM. (drcalapai.com)
  • In an earlier study he had shown that "Autologous stem cell transplantation led to significant improvement in cardiac function in patients undergoing off-pump coronary artery bypass grafting for ischemic cardiomyopathy. (cellmedicine.com)
  • Several preliminary reports have demonstrated that local stem cell transplantation in patients with acute myocardial infarction is safe and may lead to improved myocardial function and perfusion. (escardio.org)
  • 1 , 2 , 4 - 6 Specifically, patients with lactate dehydrogenase ≥2 times the upper limit of normal (ULN) at diagnosis, R/R disease within 6 months of diagnosis, multisite relapse, and/or R/R disease with bone marrow involvement experience a significantly decreased OS ( Table 1 ). (jnccn.org)
  • Refractory patients and patients who have received autologous or allogeneic stem cell transplantation are not eligible. (stanford.edu)
  • T cell PTLD is rare, particularly in pediatric patients. (karger.com)
  • Researchers from Northwestern University's Feinberg School of Medicine appear to have reversed the neurological dysfunction of early-stage multiple sclerosis patients by transplanting their own immune stem cells into their bodies and thereby "resetting" their immune systems. (scienceblog.com)
  • The 21 patients in the trial, ages 20 to 53, had relapsing-remitting multiple sclerosis that had not responded to at least six months of treatment with interferon beta. (scienceblog.com)
  • After an average follow-up of three years after transplantation, 17 patients (81 percent) improved by at least one point on a disability scale. (scienceblog.com)
  • In previous studies, Burt had transplanted immune stem cells into late-stage MS patients. (scienceblog.com)
  • Disability worsening was assessed by the cumulative proportion of patients with a 6-month confirmed disability progression (CDP) according to the Expanded Disability Status Scale (EDSS) score. (mssm.edu)
  • Currently, whole-body X-ray scan is the most commonly used diagnostic tool in the evaluation of bone involvement in patients with MM, due to the rare occurrence of extraosseous sites. (hindawi.com)
  • In the meantime, we believe that patients with cerebral palsy can be treated with their own bone marrow SCs when their cord blood SCs were not preserved. (parentsguidecordblood.org)
  • Between May 2005 and February 2010, 126 consecutive patients underwent intramyocardial cell injection. (tci-thaijo.org)
  • In the coming time, the hospital will continue to carry out autologous stem cell transplantation for pediatric patients with solid tumors and to implement allogeneic stem cell transplantation in the treatment of bone marrow failure, blood cancer or Thalassemia. (baothuathienhue.vn)
  • Ninety eligible patients will be randomly assigned at a ratio 1:1:1 to one of the following: control group (n = 30), low-cell dose treatment group (n = 30), and high-cell dose treatment group (n = 30). (unav.edu)
  • Treatment will be administered in a single-dose way and patients will be followed for 12 months. (unav.edu)
  • In a first escalating-dose phase, three patients were included sequentially in three dose cohorts (10×106, 50×106 and 100×106 cells). (unav.edu)
  • Results: 21 bone marrow samples were obtained from 17 patients. (unav.edu)
  • After a median follow-up of 42 months, 21 patients were alive, and 15 remained disease free. (elsevierpure.com)
  • Jalali et al reported that levels of soluble programmed cell death protein 1 (PD-1) ligands are elevated in patients with Waldenström macroglobulinemia and, in addition to surface-bound ligands in bone marrow, could regulate T-cell function. (medscape.com)
  • Patients with APL may be stratified into 3 risk categories on the basis of white blood cell (WBC) count and platelet count. (medscape.com)
Immunology1
  • This work was supported in part by the Practical Research Project for Allergic Diseases and Immunology (Research Technology of Medical Transplantation) from the Japan Agency for Medical Research and Development, AMED, under Grant Number 19ek0510023h0002. (elsevierpure.com)
Aplastic2
Lymphoproliferative disorders1
  • Draoua HY, Tsao L, Mancini DM, Addonizio LJ, Bhagat G, Alobeid B: T-cell post-transplantation lymphoproliferative disorders after cardiac transplantation: a single institutional experience. (karger.com)
Diffuse2
  • Diffuse alveolar hemorrhage (DAH) is a non-infectious pulmonary complication of bone marrow transplantation (BMT) with resultant high mortality. (nih.gov)
  • Ewing's sarcoma (ES) was first described by James Ewing in 1921 as a 'diffuse endothelioma of bone' (Ewing 1921). (sarcomahelp.org)
Haematological1
  • MM is considered relative paucity of CNS invasion by MM an incurable disease despite various meth- in comparison with other tumours, whether ods of treatment, including autologous bone solid or haematological, remain unknown, marrow transplantation [ 3 ]. (who.int)
Infections3
  • Allogeneic stem cell transplantation treats the recurring and life-threatening infections this condition causes. (clevelandclinic.org)
  • With damaged bone marrow, the body's immune system becomes weak and it increases the patient's risk of infections. (yapitahealth.com)
  • During this time you will be more at risk of infections (due to the lack of infection-fighting white blood cells ) and bleeding (due to a lack of platelets ). (leukaemia.org.au)
Proliferation2
  • There are multiple mechanisms and differential diagnosis includes: artifactual thrombocytopenia, accelerated platelet destruction (intra- or extra-corpuscular anomalies), deficient production (bone marrow failure, disordered proliferation or thrombopoietin deficiency), and abnormal distribution (disorders associated with splenomegaly or dilution in massive transfusions) ( 1 ). (spandidos-publications.com)
  • They are regulators of transmembrane Ca2+ conductance and thought to play a role in B-cell activation and proliferation. (lookformedical.com)
Umbilical2
Cancers2
Spleen2
  • [2] [9] Enlargement of the spleen and low red blood cells ( anemia ) may also occur. (wikipedia.org)
  • Involvement of other organs, such as spleen, liver, or bone marrow is an indication of advanced disease. (vin.com)
Peripheral Blood Stem Cell1
Cancerous cells2
  • [17] Less commonly, the disease comes to light only after the cancerous cells overwhelm the bone marrow, resulting in low red blood cells, neutrophils, or platelets. (wikipedia.org)
  • The conditioning method suppresses the immune system and destroys cancerous cells. (yapitahealth.com)
Aspiration1
  • Individuals underwent bone marrow aspiration (80 to 100 ml) from the posterior-superior iliac spine below short general anaesthesia. (ephb4inhibitor.com)
Complications3
  • Han CS, Miller W, Haake R, Weisdorf D . Varicella zoster infection after bone marrow transplantation: incidence, risk factors and complications. (nature.com)
  • The cer is about 2%-5% and as high as 26% in most common complications include renal small-cell lung carcinoma [ 5 ]. (who.int)
  • The use of ASCs in regenerative medicine and tissue engineering research has important advantages in comparison with ESCs, since there are no ethical complications and the process of differentiation of these cells is better controlled. (bvsalud.org)
Treatment7
  • An inexorable pattern of progression is characteristic, with a median time to treatment failure of less than 18 months. (medscape.com)
  • She initially declined antimyeloma treatment but 6 months later, following vertebral collapse at T5 and T12, started cyclophosphamide, thalidomide and dexamethasone (CTD) treatment. (bmj.com)
  • Treatment was frequently interrupted and dose adjusted to account for neutropenia and despite a minor response after six cycles (starting M-protein 47 g/L, finishing M-protein 34 g/L), in October 2009, she proceeded with stem cell mobilisation. (bmj.com)
  • Before starting cancer treatment, doctors remove stem cells from your blood or bone marrow. (yapitahealth.com)
  • After you have finished this treatment, your stem cells are thawed and reinfused through a vein into your bloodstream. (leukaemia.org.au)
  • These cells have been studied for the treatment of periodontitis, bone repair, regeneration of the pulp after necrosis as well as the development of new teeth. (bvsalud.org)
  • 8,9 Because dental stem cells (DSCs) are easy to obtain and present a great potential of differentiation, there has been a growing interest in their use in regenerative medicine for treatment of various human diseases. (bvsalud.org)
Lymph1
Immune4
  • This is a group of rare disorders caused by mutations in different genes involved in the development and function of infection-fighting immune cells. (clevelandclinic.org)
  • Chronic Granulomatous Disease , autoimmune diseases Autoimmune diseases Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. (lecturio.com)
  • After the transplantation, the patient's new lymphocytes or immune cells are self-tolerant and do not attack the immune system. (scienceblog.com)
  • It will take 6 to 12 months or more for your child's blood counts and immune system to fully recover. (medlineplus.gov)
Mononuclear2
  • Reduction in insulin doses correlated with stimulated C-peptide response at the baseline ( r = 0.83, P = 0.047) and mononuclear cell count of infused stem cells ( r = 0.57, P = 0.04). (drcalapai.com)
  • Briefly, the mononuclear cell fraction was isolated by Ficoll density gradient. (ephb4inhibitor.com)
Embryonic stem1
Differentiation1
  • Moreover, it seems that paracrine action of skeletal myoblasts facilitate neighboring cardiomyocytes to maintain their replicative potential and/or stimulate differentiation of native cardiac stem cells (8,9). (escardio.org)
Infiltration2
  • A study by Pasricha et al found that bone marrow features, particularly the degree of plasma cell infiltration, correlates with IgM paraprotein concentration at diagnosis. (medscape.com)
  • The prevalence production, lytic lesions and increased of leptomeningeal infiltration in breast can- plasma cells in the bone marrow [ 1 ]. (who.int)