A 31-year-old woman with no history of systemic autoimmune disease developed bilateral pain, redness, periorbital edema, and proptosis while being hospitalized for mild coronavirus disease 2019 (COVID-19) pneumonia. (jhsmr.org)
Disease1
Primary Sjögren's syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation. (biomedcentral.com)
Sicca4
Either suture or pocket techniques are recommended to allow for proper function of the gland and to decrease the incidence of keratoconjunctivitis sicca (KCS). (msdvetmanual.com)
2009. A new model of experimental autoimmune keratoconjunctivitis sicca (KCS) induced in Lewis rat by the autoantigen Klk1b22. (nih.gov)
In an attempt to define the molecular bases underlying onset of dacryoadenitis and subsequently keratoconjunctivitis sicca (or xerophthalmia) in the C57BL/6.NOD-Aec1Aec2 mouse model, we have carried out a study utilizing microarray technology. (elsevierpure.com)
DES is also called keratoconjunctivitis Sicca (KCS), keratitis sicca, sicca syndrome, xerophthalmia, Dry Eye Disease (DED), Ocular Surface Disease (OSD), or Dysfunctional Tear Syndrome (DTS), or simply dry eyes [1]. (crimsonpublishers.com)
Systemic3
Although multiple mouse strains have been advanced as models for Sjögren's syndrome (SS), which is a human systemic autoimmune disease characterized primarily as the loss of lacrimal and salivary gland functions, the C57BL/6.NOD- Aec1Aec2 recombinant inbred (RI) mouse derived from the NOD/ShiLtJ line is considered one of the more appropriate models exhibiting virtually all the characteristics of the human disease. (nih.gov)
[1] CRION is a diagnosis of exclusion, and other demyelinating, autoimmune, and systemic causes should be ruled out. (mdwiki.org)
[2] Corticosteroid responsive optic neuritis not associated with demyelinating disease should also be ruled out, including sarcoidosis , systemic lupus erythematosus , or other systemic autoimmune disease. (mdwiki.org)
Lacrimal gland1
MATERIALS AND METHODS: We retrospectively reviewed 91 consecutive patients who underwent surgical biopsy for chronic diffuse lacrimal gland enlargement and were diagnosed with non-specific dacryoadenitis (DA) (n = 42), immunoglobulin G4-related dacryoadenitis (IgG4-RD) (n = 33), and lymphoma (n = 16). (bvsalud.org)