Loading...
  • clinical
  • This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. (routledge.com)
  • Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. (routledge.com)
  • As the embryonic stem cell-related ethical issues involving creation and destruction are resolved, their clinical application may follow the clinical paths, trails, and trials already being explored with hematopoietic stem cells. (routledge.com)
  • Abrogation of new clinical relapses and brain lesions can be seen after ablative aHSCT, accompanied by significant reductions in Th17, but not Th1, cell populations and activity. (frontiersin.org)
  • Epidemiology, pathogenesis, and potential treatment options for the various clinical syndromes that are associated with CKD in hematopoietic cell transplantation patients is reviewed. (asnjournals.org)
  • The promising preclinical and clinical data that we review below suggest that cell therapy could represent a major advance in the clinical management of this difficult problem. (intechopen.com)
  • Regenerative medicine represents a new interdisciplinary field of clinical science focused on the development and implementation of novel strategies to enhance the process of regeneration of impaired cells, tissues and organs as well as replacing damaged cells with new, fully functional cells of the required phenotype [ 1 , 2 ]. (intechopen.com)
  • The first cell based approach for the treatment of full-thickness cartilage or osteochondral lesions was performed in 1994 by Lars Peterson and Mats Brittberg who pioneered clinical autologous chondrocyte implantation (ACI) 5 . (jove.com)
  • reconstitution
  • We identified an increase in the kinetics of natural killer (NK) cell reconstitution, relative to CD4 + T cells, in MS patients post-aHSCT, resulting in an increased NK cell:CD4 + T cell ratio that correlated with the degree of decrease in Th17 responses. (frontiersin.org)
  • Together these data suggest that rapid reconstitution of NK cells following aHSCT contribute to the suppression of the re-emergence of Th17 cells. (frontiersin.org)
  • progenitor cells
  • The purpose of this study is to measure and characterize the circulating endothelial progenitor cells from the blood of 30 participants and also to determine the extent of vascular cell apoptosis and proliferation in cutaneous microvasculature in these participants before and after the receipt of the two SCOT treatment regimens. (clinicaltrials.gov)
  • 1996
  • Araga S, Galin FS, Kishimoto M, Adachi A, Blalock JB (1996) Prevention of experimental autoimmune myasthenia gravis by a monoclonal antibody to a complementary peptide for the main immunogenic region of the acetylcholine receptors. (springer.com)
  • immunosuppression
  • Although iatrogen immunosuppression took away the fatality of many autoimmune skin disorders, there are several pitfalls associated with longterm immunosuppression. (springer.com)
  • myeloablative
  • Prophylactic drugs against GVHD typically continue to day 80 after transplantation after myeloablative conditioning regimens but may be tapered earlier than this after nonmyeloablative conditioning to promote a graft- versus -tumor effect. (asnjournals.org)
  • infusion
  • With the infusion of 5 million CD34+ cells, the recovery time for platelets to a target of 20,000/μL is possible within 2 weeks. (medscape.com)
  • Pathogenesis
  • This translocation involved rearrangement of a proto-oncogene called BCL-1 for B-cell leukemia-1 [46, and called later PRADI , a proto-oncogene involved in the pathogenesis of mantle-cell lymphoma. (cancernetwork.com)
  • subsets
  • In autoimmunity, the balance of different helper T (Th) cell subsets can influence the tissue damage caused by autoreactive T cells. (frontiersin.org)
  • disorders
  • Haemolytic anaemia in early infancy is often a result of blood group incompatibility, hereditary red cell morphological disorders such as congenital spherocytosis and elliptocytosis, and in certain Mediterranean and Asian regions, red cell enzyme abnormalities, including glucose-6-phosphate dehydrogenase deficiency. (bmj.com)
  • The medical management of autoimmune skin disorders is complex. (springer.com)
  • therapy
  • It's encouraging to see that stem cell therapy is gaining favor in light of several new reports showing promise, and even better than pharmaceutical drugs that can cost over $10,000 a month. (mystemcellusa.com)
  • Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes. (gulfcoaststemcell.com)
  • In this scenario, cell therapy is envisaged as an effective alternative to surgery. (intechopen.com)
  • It is as a result of these inadequacies in current treatment strategies that cell therapy has arisen as a complementary option [ 14 ]. (intechopen.com)
  • In a list of individuals treated in their "stem cell therapy data" cerebral palsy is listed. (spiritofilithyia.com)
  • To improve the effectiveness of such regeneration processes, one of the potential approaches is application of stem cell (SC)‐based therapy. (intechopen.com)
  • This study aimed to evaluate the long term economic impact of autologous transplantation with respect to conventional therapy. (jove.com)
  • immunotherapy
  • Type of passive immunotherapy (treatment that is prepared outside the body) that involves the transfer of immune cells to a patient. (themmrf.org)
  • tissue
  • Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. (routledge.com)
  • Placenta tissue stem cells can also be used to benefit the mother. (spiritofilithyia.com)
  • In contrast to other surgical techniques, which often lead to the formation of fibrous or fibrocartilaginous tissue, Tissue Engineering aims at fully restoring the complex structure and properties of the original articular cartilage by using the chondrogenic potential of transplanted cells. (jove.com)