Neurodegenerative DiseasesNerve DegenerationAmyotrophic Lateral SclerosisNeuronsAlzheimer Diseasetau ProteinsHuntington DiseaseBrainParkinson Diseasealpha-SynucleinNerve Tissue ProteinsTauopathiesNeuroprotective AgentsDisease Models, AnimalInclusion BodiesHeredodegenerative Disorders, Nervous SystemProteostasis DeficienciesMicrogliaPrionsPrion DiseasesMice, TransgenicSynucleinsAmyloid beta-PeptidesSpinocerebellar AtaxiasFrontotemporal Lobar DegenerationCell DeathOxidative StressMutationTrinucleotide Repeat ExpansionFrontotemporal DementiaFriedreich AtaxiaMitochondriaAutophagyNeuronal Ceroid-LipofuscinosesGuamAmyloidAgingDementiaProtein FoldingCells, CulturedNeurofibrillary TanglesLewy Body DiseaseAstrocytesPeptidesNeurotoxinsParkinsonian DisordersSuperoxide DismutaseMice, Inbred C57BLModels, BiologicalLewy BodiesAxonal TransportCentral Nervous SystemTrinucleotide RepeatsMotor Neuron DiseaseSupranuclear Palsy, ProgressiveMitochondrial DiseasesMotor NeuronsUbiquitinCentral Nervous System DiseasesHippocampusCycasIron-Binding ProteinsProteasome Endopeptidase ComplexMuscular Atrophy, SpinalCerebral CortexPick Disease of the BrainSignal TransductionCell SurvivalRNA-Binding Protein FUSNeurogliaGliosisApoptosisGene Expression RegulationNervous System DiseasesPlaque, AmyloidReactive Oxygen SpeciesMultiple System AtrophyNuclear ProteinsAnimals, Genetically ModifiedSubstantia NigraMolecular ChaperonesPrPSc ProteinsImmunohistochemistrybeta-SynucleinRotarod Performance TestAmino Acids, DiaminoParkinson Disease, SecondaryAxonsIntranuclear Inclusion BodiesDNA Repeat ExpansionSpinal CordDopaminergic NeuronsAtrophyBlotting, WesternCorpus StriatumTDP-43 ProteinopathiesAntioxidantsCyclin-Dependent Kinase 5PhenotypeNeurofilament Proteins