Autocrine CommunicationExtracellular Signal-Regulated MAP KinasesEnzyme ActivationMAP Kinase Signaling SystemMitogen-Activated Protein KinasesMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Signal TransductionButadienesPhosphorylationMitogen-Activated Protein Kinase KinasesFlavonoidsMAP Kinase Kinase 1NitrilesEnzyme InhibitorsCells, CulturedProto-Oncogene Proteins c-rafCell Lineras ProteinsCell DivisionMAP Kinase Kinase 2Paracrine CommunicationBlotting, WesternReceptor, Epidermal Growth FactorCell Line, TumorCell ProliferationEpidermal Growth FactorJNK Mitogen-Activated Protein KinasesRNA, MessengerTransfectionProtein-Serine-Threonine KinasesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins A-rafraf KinasesTumor Cells, CulturedProtein Kinase CArrestinsProtein-Tyrosine Kinasessrc-Family KinasesApoptosisCalcium-Calmodulin-Dependent Protein KinasesAminoacetonitrileCell SurvivalReceptors, Autocrine Motility FactorRNA, Small InterferingProto-Oncogene Proteins c-aktAdaptor Proteins, Signal TransducingCell MovementFibroblastsModels, BiologicalUp-RegulationDose-Response Relationship, DrugGene Expression RegulationProto-Oncogene ProteinsRats, Sprague-DawleyCell DifferentiationTime FactorsReverse Transcriptase Polymerase Chain ReactionTransforming Growth Factor alphaDual Specificity Phosphatase 6ets-Domain Protein Elk-1Platelet-Derived Growth FactorProtein Tyrosine PhosphatasesMAP Kinase Kinase KinasesProtein BindingProto-Oncogene Proteins B-rafEpithelial Cellsp38 Mitogen-Activated Protein KinasesSon of Sevenless Protein, DrosophilaTyrosineMice, KnockoutDown-RegulationPC12 CellsReceptor Cross-TalkImmunoblottingIntracellular Signaling Peptides and Proteins3T3 CellsProtein Tyrosine Phosphatase, Non-Receptor Type 11COS CellsProtein Kinase InhibitorsShc Signaling Adaptor ProteinsGRB2 Adaptor ProteinMAP Kinase Kinase Kinase 1Phospholipase C gammaMice, Inbred C57BLTyrphostinsGlucose-6-Phosphate IsomeraseInterleukin-1Dual Specificity Phosphatase 1Gene ExpressionMitogen-Activated Protein Kinase 7ImmunohistochemistryTransforming Growth Factor betaPrecipitin TestsImmunoprecipitationGene Expression Regulation, EnzymologicMutationGrowth SubstancesCell Line, TransformedRecombinant Proteins