Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter. (lookformedical.com)
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. (lookformedical.com)
Histamine1
Mast cells and histamine are triggering the NF-?B-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation. (ucdenver.edu)
Cells3
Primary reports also have provided evidence that PEA downregulates hyperactive mast cells in a dose-dependent manner, and that it alleviates pain elicited in mouse models. (wikipedia.org)
For example, macrophages predominantly generate PGE 2 and TXA 2 , whereas mast cells produce PGD 2 [ 12 ]. (biomedcentral.com)
When an allergen is encountered, it binds to IgE, which excessively activates the mast cells or basophils, leading them to release massive amounts of histamines. (slideshare.net)
Infiltration1
In a spinal trauma model, PEA reduced the resulting neurological deficit via the reduction of mast cell infiltration and activation. (wikipedia.org)
Peripheral1
The cat lung strip as an in vitro preparation of peripheral airways: a comparison of beta-adrenoceptor agonists, autacoids and anaphylactic challenge on the lung strip and trachea. (lookformedical.com)
Cell2
non-primary source needed] the expression of mast cell receptors sensitive to the two molecules was demonstrated by Levi-Montalcini and coworkers. (wikipedia.org)
Notably, high B cell counts and low Mast cell counts were connected to a poor prognosis in KIRC patients. (bvsalud.org)