• Perform active surveillance testing for methicillin-resistant S. aureus (MRSA) colonization in neonatal intensive care unit patients when there is evidence of ongoing healthcare-associated transmission within the unit. (cdc.gov)
  • Appropriate procedures to allow discontinuation of Contact Precautions for individual neonatal intensive care unit patients who have a history of colonization or infection with methicillin-resistant S. aureus (MRSA) is an unresolved issue. (cdc.gov)
  • Both community-associated and hospital-acquired infections with Staphylococcus aureus have increased in the past 20 years, and the rise in incidence has been accompanied by a rise in antibiotic-resistant strains-in particular, methicillin-resistant S aureus (MRSA) and, more recently, vancomycin-resistant strains. (medscape.com)
  • CA-MRSA) infections have rapidly emerged in Canada ( 1 ). (cdc.gov)
  • These CA-MRSA strains are causing infections in often young otherwise healthy persons with no traditional health care- associated risk factors ( 2 ), linked with increased illness severity and deaths ( 3 ), and now entering and being disseminated within health care facilities ( 4 ). (cdc.gov)
  • has been directed at the emerging problem of CA-MRSA or CA-methicillin-susceptible S. aureus (MSSA) in rural and northern communities of Canada. (cdc.gov)
  • In this study, active surveillance was undertaken in 3 remote northern communities to assess the prevalence and effects of MRSA and MSSA infections. (cdc.gov)
  • Over the 2-year study period, rates of MRSA and MSSA infections in the 3 communities ranged from 146-482/10,000 and 112-329/10,000 population, respectively. (cdc.gov)
  • Trends of seasonality were apparent for MRSA infections, with the highest rates being observed in the third and fourth quarters of the year (Figure 1). (cdc.gov)
  • Overall, the highest quarterly rates of MRSA and MSSA infections were observed at site C, with 738/10,000 and 610/10,000 population, respectively. (cdc.gov)
  • Both bacterial and host factors contribute to complicated bloodstream infection (BSI) caused by Staphylococcus aureus including methicillin-resistant S . aureus (MRSA). (scirp.org)
  • Methicillin-resistant Staphylococcus aureus (MRSA) remains an important nosocomial pathogen, although the organism has increasingly been recognized as a significant cause of community-acquired infection around the world. (canada.ca)
  • Surveillance for MRSA in sentinel Canadian hospitals participating in the Canadian Nosocomial Infection Surveillance Program (CNISP) has been ongoing since its inception in January 1995. (canada.ca)
  • The presence of infection caused by MRSA was determined according to standard definitions (4) . (canada.ca)
  • MRSA colonization was defined as the presence of MRSA without any clinical signs or symptoms of infection. (canada.ca)
  • MRSA was thought to have been hospital-acquired if, in the judgment of the infection control professional, there was no evidence that the organism was present at the time of admission to hospital, or if there was evidence that it was likely to have been acquired during a previous hospital admission. (canada.ca)
  • A total of 6,435 (38%) patients were thought to have had an MRSA infection. (canada.ca)
  • Despite decreasing incidence in many countries, severe infections caused by methicillin-resistant Staphylococcus aureus ( S aureus, MRSA) continue to pose therapeutic challenges. (bmj.com)
  • Lane JW, Tang J, Taggard D, Byun R. Successful use of daptomycin and linezolid, without surgical intervention, in the treatment of extensive epidural abscess and bacteremia due to methicillin-resistant Staphylococcus aureus (MRSA). (medscape.com)
  • Given that vitamin D (25(OH)D) contributes to immunity, we sought to determine if 25(OH)D deficiency was significantly associated with Methicillin-resistant Staphylococcus aureus (MRSA) infection. (emory.edu)
  • These patients were matched with an on-going study of patients with well-characterized MRSA infection (2005-10). (emory.edu)
  • Patients with 25(OH)D determinations without an MRSA infection served as controls. (emory.edu)
  • A total of 6405 patients with 25(OH)D determinations were included in the analyses, of which 401 (6.3%) experienced an MRSA infection during the study period. (emory.edu)
  • Further study is necessary to investigate this association in other populations and to determine if optimization of 25(OH)D levels could potentially be useful for prevention or treatment of MRSA infection. (emory.edu)
  • Season of MRSA Infection. (emory.edu)
  • In November 2012, an outbreak of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections affecting students at a boarding school in Hong Kong (China) was detected. (who.int)
  • A case was defined as any student or staff notified with MRSA infection from 25 October 2012 to 5 July 2013 with the clinical isolate being of staphylococcal cassette chromosome mec type IV or V and positive for Panton-Valentine leukocidin gene. (who.int)
  • Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) outbreaks in schools usually affect members of sports teams who come into bodily contact with one another. (who.int)
  • Medical practitioners are required to report any patient with confirmed MRSA infection fulfilling the surveillance definition and to submit the culture isolate to a government public health laboratory for CA-MRSA confirmatory testing. (who.int)
  • A case was defined as any student or staff member of School X who was notified with SSTIs (e.g. boil, abscess and pustule) or other infections (e.g. pneumonia, sepsis) from 25 October 2012 to 5 July 2013, with MRSA isolated from any clinical specimen with the isolate being of staphylococcal cassette chromosome mec (SCC mec ) type IV or V and positive for Panton-Valentine leukocidin (PVL) gene. (who.int)
  • A carrier was any student or staff member of School X, without a clinical infection, who had MRSA isolated from any screening specimen collected from 25 October 2012 to 5 July 2013 with the isolate being of SCCmec type IV or V and positive for PVL gene. (who.int)
  • Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly common multidrug-resistant clinical pathogen responsible for increasing health costs and for patient morbidity and mortality. (psu.edu)
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a strain of Staph that is resistant to certain antibiotics, which can make MRSA infections more difficult to treat. (massgeneral.org)
  • MRSA can cause serious bloodstream infections and is often spread through direct contact with an infection or contaminated hands. (massgeneral.org)
  • The Centers for Medicare and Medicaid Services (CMS) reports MRSA using a standardized infection ratio (SIR). (massgeneral.org)
  • S. aureus is one of the leading pathogens for deaths associated with antimicrobial resistance and the emergence of antibiotic-resistant strains, such as methicillin-resistant S. aureus (MRSA), is a worldwide problem in clinical medicine. (wikipedia.org)
  • Methicillin-resistant Staphylococcus aureus (MRSA) colonization leads to increased infection rates and mortality. (lumc.nl)
  • Obtain the MRSA typing that caused invasive infections in children by using the automated multi-locus variable number of tandem repeats (MLVA) analysis technique. (una.py)
  • In particular, methicillin-resistant S. aureus (MRSA) has emerged as a major clinical and epidemiological problem in hospitals. (biomedcentral.com)
  • MRSA strains have the ability to be resistant to most β-lactam antibiotics, but also to a wide range of other antimicrobials, making infections difficult to manage and very costly to treat. (biomedcentral.com)
  • Methicillin resistant S. aureus (MRSA) has become a major public health predicament worldwide. (who.int)
  • Health facilities in the state should institute effective antimicrobial stewardship, intensify surveillance and screening of Staphylococcus aureus for MRSA strains to guard against dissemination of multidrug resistant strains in both hospital and community settings because of the clinical implications. (who.int)
  • This was a cross sectional hospital- vancomycin as the drug of choice in the treatment of based study involving 300 patients of all ages with 6 infections caused by MRSA. (who.int)
  • Rates of methicillin-resistant infections were extremely high (146-482/10,000 population), and most (98.2%) were caused by USA400 strains. (cdc.gov)
  • A novel class of small amphipathic peptides with strong surfactant-like properties, the phenol soluble modulins, particularly PSMα as well as the leukocidin LukAB, are involved in phagosomal escape of the clinical S. aureus strains LAC, MW2 and 6850 in non-professional and professional phagocytes. (uni-wuerzburg.de)
  • This could be confirmed by an infection assay including S. aureus knockout mutants in psmα or lukAB which were significantly less cytotoxic, compared with those infected with escape-positive wild type strains. (uni-wuerzburg.de)
  • This review will focus on the most relevant components of UPEC arsenal of pathogenicity together with the major host responses to infection, the current approved treatment and the emergence of resistant UPEC strains, the vaccine strategies, the natural antimicrobial compounds along with innovative anti-adhesive and prophylactic approaches to prevent UTIs. (scienceopen.com)
  • Staphylococcus aureus strains that produce Panton-Valentine leukocidin are known to cause community infections . (bvsalud.org)
  • Pathogenic strains often promote infections by producing virulence factors such as potent protein toxins, and the expression of a cell-surface protein that binds and inactivates antibodies. (wikipedia.org)
  • Only a few strains of S. aureus are associated with infections in humans. (wikipedia.org)
  • In noncorrected follow-up analysis, the investigators found greater efficacy against methicillin-sensitive compared with methicillin-resistant strains, in superficial vs deep surgical site infections, and in patients who already had nasal S aureus colonization vs those who did not. (medscape.com)
  • In this study, we analysed the antimicrobial susceptibility patterns of biofilm-producing S. aureus strains isolated from diabetic foot infections. (biomedcentral.com)
  • Nasal ointments or sprays and oral antibiotics have variable efficacy, and their use frequently results in antimicrobial resistance among S aureus strains. (johnshopkins.edu)
  • Nearly all strains of Staphylococcus aureus in the United States are resistant to penicillin, and many are resistant to newer methicillin-related drugs. (mo.gov)
  • Since 1997, strains of S. aureus have been reported to have a decreased susceptibility to vancomycin, which has been the last remaining uniformly effective treatment. (mo.gov)
  • LL-37 susceptibility among S. aureus isolates causing uncomplicated and complicated BSI was investigated. (scirp.org)
  • S. McNicholaswhj, H. Humphreys and D. Hughes, "Susceptibility of Staphylococcus aureus Isolates Causing Bloodstream Infection to the Antimicrobial Peptide LL-37," Open Journal of Medical Microbiology , Vol. 3 No. 1, 2013, pp. 80-83. (scirp.org)
  • S. McNicholas, A. C. Shore, D. C. Coleman, H. Humphreys and D. F. Hughes, "DNA Microarray Genotyping and Virulence and Antimicrobial Resistance Gene Profiling of Methicillin-Resistant Staphylococcus aureus Bloodstream Isolates from Renal Patients," Journal of Clinical Microbiology, Vol. 49, No. 12, 2011, pp. 4349-4351. (scirp.org)
  • Bacterial isolates from infected wounds and their antibiotic susceptibility pattern: some remarks about wound infection. (scienceopen.com)
  • OBJECTIVES: To determine the usefulness of flucloxacillin as empirical therapy for putative Staphylococcus aureus infections in intensive care unit (ICU) patients in the Netherlands, the antibiotic resistance of S. aureus isolates from ICUs over a 13 year period was investigated. (ru.nl)
  • METHODS: From 1996 to 2008, 1146 consecutive S. aureus isolates from ICU patients in 14 large referral hospitals were collected. (ru.nl)
  • In vitro, AB-SA01 killed 94.5% of 401 clinical Staphylococcus aureus isolates, including methicillin-resistant and vancomycin-intermediate ones for a total of 95% of the 205 known multidrug-resistant isolates. (pacb.com)
  • Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus Aureus Infections in Adults and Children. (medscape.com)
  • A variety of infections are caused by S aureus but origins of this bacteria from the biliary tract is rare and there are scant case reports and no clinical studies available to provide any data on the involvement of the biliary tract. (infectiousdiseaseadvisor.com)
  • Our research focuses on promoting good use of antibiotics through clinical and epidemiological research on the treatment of infections. (lumc.nl)
  • This research is closely connected with our clinical and epidemiological research regarding biofilm-associated infections, e.g. prosthetic joint infection and fracture-related infection ( www.protheseinfectie.nl ). (lumc.nl)
  • Tsukayama et al based their treatment of infections after total hip arthroplasty (THA) on the clinical presentation-that is, positive intraoperative cultures, early postoperative infection, acute hematogenous infection, or late chronic infection. (medscape.com)
  • resistant S. aureus (VRSA) in clinical samples The study was approved by the Health Ethics impacted negatively on the efficacy of vancomycin Committee of the State Ministry of Health and the 6 leading to treatment failures. (who.int)
  • SNAP is a multicentre, pragmatic, multi-arm, open-label adaptive platform trial which aims to identify the effects of a range of clinical interventions on patients with Staphylococcus aureus Bacteraemia (SAB) in order to improve clinical outcomes. (who.int)
  • Perform active surveillance testing for S. aureus colonization in neonatal intensive care unit patients when there is an increased incidence of S. aureus infection or in an outbreak setting. (cdc.gov)
  • The use of active surveillance testing for methicillin-sensitive S. aureus (MSSA) colonization in neonatal intensive care unit patients to detect ongoing healthcare-associated MSSA transmission is an unresolved issue. (cdc.gov)
  • If active surveillance testing for S. aureus colonization is implemented for neonatal intensive care unit patients, test at regular intervals to promptly identify newly colonized patients. (cdc.gov)
  • If active surveillance testing for S. aureus colonization in neonatal intensive care unit patients is implemented, consider testing outborn infants or infants transferred from other newborn care units on admission to promptly identify newly admitted colonized patients. (cdc.gov)
  • Consider targeted decolonization for S. aureus- colonized neonatal intensive care unit patients in addition to the implementation of, and adherence to, appropriate infection prevention and control measures in an outbreak setting, or when there is ongoing healthcare-associated transmission, or an increase in the incidence of infection. (cdc.gov)
  • The use of universal decolonization for S. aureus- colonized neonatal intensive care unit patients is an unresolved issue. (cdc.gov)
  • ESKD patients on dialysis are at increased risk for Staphylococcus aureus bloodstream infections, but racial, ethnic, and socioeconomic disparities associated with this outcome are not well described. (medscape.com)
  • Among seven EIP sites, the S. aureus bloodstream infection rate during 2017-2020 was 100 times higher among hemodialysis patients (4,248 of 100,000 person-years) than among adults not on hemodialysis (42 of 100,000 person-years). (medscape.com)
  • Unadjusted S. aureus bloodstream infection rates were highest among non-Hispanic Black or African American (Black) and Hispanic or Latino (Hispanic) hemodialysis patients. (medscape.com)
  • Infections are a leading cause of morbidity and mortality in hemodialysis patients. (medscape.com)
  • [ 11 ] Higher rates of invasive S. aureus infections have been observed in dialysis patients compared with nondialysis patients. (medscape.com)
  • In the study group, the presence of severe sepsis in all patients, and of septic shock in six of the 14, indicated the severity of PVL-positive S aureus bone and joint infections. (contemporarypediatrics.com)
  • In the study group, most patients failed to improve after initial treatment with intravenous (IV) antibiotics active against S aureus , after which various combinations were tried. (contemporarypediatrics.com)
  • Eculizumab and anakinra should be considered in critically ill patients with severe infections that require immunomodulating therapies for life-threatening dysregulation, according to a poster session at the 2023 American Academy of Pediatrics National Conference & Exhibition. (contemporarypediatrics.com)
  • Staphylococcus aureus Infections in Pediatric Oncology Patients: High Rates of Antimicrobial Resistance, Antiseptic Tolerance and Complications. (medscape.com)
  • Methods: Over a 5-year interval, patients in whom either E. coli or S. aureus was detected in superficial or primary sterile compartments were assessed for the primary endpoint death during hospital stay and the secondary endpoints duration of hospital stay and infectious disease as the main diagnosis. (scienceopen.com)
  • The hospital stay of patients with E. coli was increased due to third-generation cephalosporin and ciprofloxacin resistance, and in the case of patients with S. aureus due to tetracycline and fusidic acid resistance. (scienceopen.com)
  • CONCLUSIONS: The empirical choice of flucloxacillin in the case of putative S. aureus infections in patients admitted to ICUs in the Netherlands is still justified. (ru.nl)
  • Objectives: Patients with Staphylococcus aureus bacteraemia (SAB) at risk for infective endocarditis (IE) need to be identified because they should undergo echocardiography. (lu.se)
  • The measure takes into account risk factors that may impact the number of infections at a facility, including facility size, the types of patients treated and kinds of procedures performed. (massgeneral.org)
  • Each year, around 500,000 hospital patients in the United States contract a staphylococcal infection, chiefly by S. aureus. (wikipedia.org)
  • Prior to the 1940s, S. aureus infections were fatal in the majority of patients. (wikipedia.org)
  • After exclusion of patients with primary postoperative infections, the risk of a prosthesis becoming infected by means of hematogenous seeding after SAB was 34% (15 of 44 patients) for prosthetic joints and 7% (1 of 15 patients) for other orthopedic prostheses. (duke.edu)
  • We focus on (recurrent) UTI due to (particularly) resistant micro-organisms (BRMO), UTI in patients after renal transplantation, the role of the microbioma and complications of antibiotic therapy such as Clostridioides difficile infections. (lumc.nl)
  • Innovative strategies like antimicrobial peptides and bacteriophages are urgently needed to improve outcome for patients with these complex infections. (lumc.nl)
  • A vaccine to prevent postoperative infection with Staphylococcus aureus in patients undergoing cardiothoracic surgery is associated with an overall lack of efficacy and a higher mortality rate among patients who become infected, according to a study published in the April 3 issue of JAMA . (medscape.com)
  • Case-fatality ratios approach 50% in patients with S aureus infection after bypass surgery or valve replacement. (medscape.com)
  • The vaccine elicited antibodies but was not significantly more effective in preventing infection than placebo (22/3528 for recipients included in the analysis vs 27/3517 for control patients) at any time during the trial. (medscape.com)
  • The objective of this review of the English language literature and a MEDLINE search was to describe recent advances in the prevention of S aureus health care-related infections that are attributable to patients ' endogenous colonization. (johnshopkins.edu)
  • Given the importance of S aureus nosocomial infections and the increased risk of S aureus nasal carriage in patients with health care-related infections, investigators must study cost-effective strategies to further prevent certain types of health care-related infections or nosocomial infections that occur in specific settings. (johnshopkins.edu)
  • Perl, TM 2003, ' Prevention of Staphylococcus aureus infections among surgical patients: Beyond traditional perioperative prophylaxis ', Surgery , vol. 134, no. 5 SUPPL. (johnshopkins.edu)
  • A prospective trial is not feasible in military patients owing to dangerous conditions of injury but a trial examining infection pathogenesis and bacterial pathogen-specific outcomes by evaluating host immune response using modern genomic and proteomic molecular techniques would provide valuable information and could be carried out at a large academic trauma center. (medscape.com)
  • Patients who had an early postoperative infection are managed with débridement, replacement of the polyethylene (PE) insert of the acetabular/tibial component, retention of the prosthesis, and IV administration of antibiotics for 6 weeks. (medscape.com)
  • Patients who have an acute hematogenous infection are also managed with débridement, replacement of the PE insert, retention of the prosthesis if it is not loose, and IV administration of antibiotics for 6 weeks. (medscape.com)
  • Certain necessary treatments (including antibiotics, chemotherapy, surgery, and catheters) can make patients more vulnerable to germs that cause these infections. (oregon.gov)
  • This study was conducted to investigate the prevalence of methicillin resistance Staphylococcus aureus among patients in two health facilities in Akwa Ibom State, Nigeria. (who.int)
  • Meticillin-Resistant Staphylococcus Aureus Infection -- the Infectious Stigma of Our Time? (georgetown.edu)
  • The aim of this paper is to complement this knowledge by investigating the worm's response to a Staphylococcus aureus infection through a 2-dimensional differential proteomics approach. (biomedcentral.com)
  • Outbreak of Panton-Valentine Leukocidin-Associated Methicillin-Susceptible Staphylococcus aureus Infection in a Rugby Team, France, 2010-2011. (bvsalud.org)
  • In an in vivo rabbit model, subtherapeutic (15-mg/kg) and therapeutic (30- or 45-mg/kg) doses of telavancin were demonstrated to be noninferior and superior to vancomycin (20 mg/kg), respectively, for preventing subcutaneous implant colonization and infection by Staphylococcus aureus. (nih.gov)
  • Staphylococcus aureus is a major pathogen that can cause a broad spectrum of serious infections including skin infections, pneumonia and sepsis. (uni-koeln.de)
  • Two reports are scheduled for revision, namely, those on prevention of intravascular infections, and prevention of nosocomial pneumonia. (cdc.gov)
  • In both neutropenic and immunocompetent mouse models of acute pneumonia, AB-SA01 reduced lung S. aureus populations equivalently to vancomycin. (pacb.com)
  • S. aureus is an important nosocomial pathogen that can cause several infections such as: bacteraemia, osteomyelitis, skin infections, pneumonia, meningitis and endocarditis. (biomedcentral.com)
  • It is recognized as one of the most important causes of both acute and chronic cases of community-acquired and hospital-associated infections including urinary tract infections, blood stream infections, soft tissue infections and 2 pneumonia. (who.int)
  • One bacterial factor that may affect the persistence of S. aureus in complicated BSI is reduced susceptibility to the innate immune defence peptide LL-37. (scirp.org)
  • Reduced LL-37 susceptibility may contribute to the persistence of S. aureus in complicated BSI. (scirp.org)
  • We screened the Nebraska Transposon Mutant Library of 1920 single-gene inactivations in S. aureus strain JE2, for increased susceptibility to the anti-staphylococcal antimicrobials (ciprofloxacin, oxacillin, linezolid, fosfomycin, daptomycin, mupirocin, vancomycin, and gentamicin). (frontiersin.org)
  • The majority of the identified genes have not previously been associated with antimicrobial susceptibility in S. aureus . (frontiersin.org)
  • The results suggest that the antibiotic susceptibility patterns cannot be applied to biofilm established infections. (biomedcentral.com)
  • The total number of healthcare-associated Methicillin-sensitive Staphylococcus aureus (MSSA) bloodstream infection patient episodes , attributed to care provided by the hospital, reported during a specified reference period. (aihw.gov.au)
  • MSSA is an isolate of Staphylococcus aureus that is identified by a laboratory as being methicillin susceptible (ACSQHC unpublished). (aihw.gov.au)
  • SSTIs), urinary tract infections, upper respiratory tract infections, and lower respiratory tract infections, were identified as S. aureus . (cdc.gov)
  • Urinary tract infections (UTIs) are one of the most common pathological conditions in both community and hospital settings. (scienceopen.com)
  • The Guideline for Prevention of Catheter-associated Urinary Tract Infections (published in 1981) is PB84-923402. (cdc.gov)
  • Some examples of HAIs are Clostridium difficile, diarrhea caused by antibiotics, surgical site infections, and urinary tract infections associated with catheters. (oregon.gov)
  • ABSTRACT Urinary tract infection (UTI) is a common problem in pregnant woman. (who.int)
  • Gram-positive organisms, for example, Streptococcus pyogenes and S. aureus , historically were major causes of morbidity and mortality following penetrating trauma in the pre-antibiotic era and remain initial pathogens for many infection types. (medscape.com)
  • Health care providers and public health professionals should prioritize prevention and optimized treatment of ESKD, identify and address barriers to lower-risk vascular access placement, and implement established best practices to prevent bloodstream infections. (medscape.com)
  • Hospital Infections Program NOTE: Guidelines for Prevention of Intravascular Device-Related Infections is currently being updated Draft version was pubished for comment in the Federal Register on 9/27/95. (cdc.gov)
  • The 'CDC Guidelines for the Prevention and Control of Nosocomial Infections' is a set of 7 reports on different aspects of hospital infection control. (cdc.gov)
  • The complete set of 'CDC Guidelines for the Prevention and Control of Nosocomial Infections' is publication No. PB86-133022. (cdc.gov)
  • The Guideline for Prevention of Intravascular Infections (published in 1981) is PB84-923403. (cdc.gov)
  • The CDC/STRIVE curriculum was developed by national infection prevention experts led by the Health Research & Educational Trust (HRET) for CDC. (cdc.gov)
  • Courses address both the technical and foundational elements of healthcare-associated infection (HAI) prevention. (cdc.gov)
  • Our aim is to summarize evidence for mupirocin decolonization for prevention of S. aureus infections in non-surgical healthcare settings. (biomedcentral.com)
  • To identify the optimal setting and patient population to implement mupirocin decolonization for prevention of S. aureus infections using meta-analytic methods. (biomedcentral.com)
  • Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (who.int)
  • 2 , 3 A single randomised controlled trial conducted more than two decades ago suggested that TMP-SMX may be a useful alternative to vancomycin for treatment of severe S aureus infections. (bmj.com)
  • Unfortunately, the suspected cases of ear, wound and urinary tract report of emergence of vancomycin intermediate infections at both tertiary (UUTH) and secondary sensitive S. aureus (VISA) and vancomycin (GHIA) healthcare facilities in Akwa Ibom State. (who.int)
  • Pääkkönen M, Kallio PE, Kallio MJ, Peltola H. Management of Osteoarticular Infections Caused by Staphylococcus aureus Is Similar to That of Other Etiologies: Analysis of 199 Staphylococcal Bone and Joint Infections. (medscape.com)
  • Much of the community-associated methicillin-resistant S aureus being seen in the United States is also PVL-positive. (contemporarypediatrics.com)
  • Retropharyngeal Abscess in Children: The Rising Incidence of Methicillin-Resistant Staphylococcus aureus. (medscape.com)
  • Elliott DJ, Zaoutis TE, Troxel AB, Loh A, Keren R. Empiric Antimicrobial Therapy for Pediatric Skin and Soft-Tissue Infections in the Era of Methicillin-Resistant Staphylococcus aureus. (medscape.com)
  • Recurrent skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus requiring operative debridement. (medscape.com)
  • Factors associated with nasal colonization of methicillin-resistant Staphylococcus aureus among healthy children in Taiwan. (medscape.com)
  • Nerby JM, Gorwitz R, Lesher L, Juni B, Jawahir S, Lynfield R. Risk Factors for Household Transmission of Community-associated Methicillin-resistant Staphylococcus aureus. (medscape.com)
  • Title : Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Methicillin-Resistant Staphylococcus aureus, 2006 (Update) Corporate Authors(s) : National Center for Immunization and Respiratory Diseases (U.S.). Division of Bacterial Diseases. (cdc.gov)
  • Taylor, AR 2013, ' Methicillin-resistant Staphylococcus aureus infections ', Primary Care - Clinics in Office Practice , vol. 40, no. 3, pp. 637-654. (psu.edu)
  • Design and Preclinical Development of a Phage Product for the Treatment of Antibiotic-Resistant Staphylococcus aureus Infections. (pacb.com)
  • Further, we aim to develop innovative treatment strategies for infections with multi-resistant pathogens. (lumc.nl)
  • Antimicrobial peptides (AMPs) and bacteriophages may offer a solution for treatment of drug-resistant infections in this era of antimicrobial resistance. (lumc.nl)
  • While multidrug-resistant infections are clearly on the rise, the cause remains unclear. (medscape.com)
  • Trials optimizing timing of antibiotic administration with regard to known antimicrobial pharmacokinetic/pharmacodynamic properties (e.g., prolonging infusion times of β-lactams to reduce bacterial resistance) should also assist in improving outcomes in penetrating traumatic infections, which are increasingly antibiotic resistant. (medscape.com)
  • Fox, TJ & Shin, AY 2012, ' Letter regarding "community-acquired methicillin-resistant staphylococcus aureus hand infections in the pediatric population" ', Journal of Hand Surgery , vol. 37, no. 10, pp. 2204. (elsevierpure.com)
  • When bacteria become resistant to antibiotics, it is often harder and more expensive to treat the infection. (mo.gov)
  • But the steady evolution of resistant bacteria has resulted in a situation in which, for some illnesses, doctors now have only one or two drugs "of last resort" to use against infections by superbugs resistant to all other drugs. (mo.gov)
  • Today, one out of six cases of Campylobacter infections, the most common cause of food borne illness, is resistant to fluoroquinolones (the drug of choice for treating food-borne illness). (mo.gov)
  • We report here that myricetin, but not its glycosylated form, can remarkably decrease the production of several S. aureus virulence factors, including adhesion, biofilm formation, hemolysis and staphyloxanthin production, without interfering with growth. (nature.com)
  • An in vitro model mimicking infection was developed in order to identify putative virulence determinants. (whiterose.ac.uk)
  • The physiopathology of diabetic foot infections (DFI) is complex, but its severity and prevalence are a consequence of host-related disorders and pathogens-factors, as virulence and antibiotic resistance traits [ 1 ]. (biomedcentral.com)
  • Several structural and secreted virulence factors play a role in S. aureus infections, which are multifactorial and depend on bacterial adherence and biofilm formation. (biomedcentral.com)
  • Areas with higher poverty levels, crowding, and lower education levels accounted for disproportionately higher proportions of hemodialysis-associated S. aureus bloodstream infections. (medscape.com)
  • Promising strategies including bacteriophages and antimicrobial peptides are being tested for their efficacy against biofilm associated infections caused by different pathogens. (lumc.nl)
  • Tests of nasopharyngeal specimens for specific pathogens are helpful when targeted therapy depends on the results (eg, group A streptococcal infection, gonococcus, pertussis). (medscape.com)
  • P. aeruginosa , S. aureus , A. Vulgaris , etc.) while kefir is also shown to support the immunity of the skin and treat skin pathogens through the production of antimicrobial substances and prebiotics. (mdpi.com)
  • Are host genetics the predominant determinant of persistent nasal Staphylococcus aureus carriage in humans? (medscape.com)
  • Over time, this parasitic relationship has led to the bacterium's ability to be carried in the nasopharynx of humans without causing symptoms or infection. (wikipedia.org)
  • We conclude that, despite peritoneal mast cells being activated by S. aureus in vitro, they do not influence the in vivo manifestations of intraperitoneal S. aureus infection. (uni-koeln.de)
  • The identification of genes important to the growth of Staphylococcus aureus in in vitro models mimicking infection. (whiterose.ac.uk)
  • Results demonstrate that very high concentrations of the most used antibiotics in treating diabetic foot infections (DFI) are required to inhibit S. aureus biofilms in vitro, which may explain why monotherapy with these agents frequently fails to eradicate biofilm infections. (biomedcentral.com)
  • The present findings reveal the potential of Myr as an alternative multi-target antivirulence candidate to control S. aureus pathogenicity. (nature.com)
  • Mobile genetic elements that are common in S. aureus include bacteriophages, pathogenicity islands, plasmids, transposons, and staphylococcal cassette chromosomes. (wikipedia.org)
  • Surveillance of Staphylococcus aureus infections in 3 northern remote communities of Saskatchewan was undertaken. (cdc.gov)
  • Implementation Guide for the Surveillance of Staphylococcus aureus bloodstream infection. (aihw.gov.au)
  • Reporting of this data element is conditional on a CODE 1 'Yes' response to the Establishment-Staphylococcus aureus bloodstream infection surveillance indicator, yes/no code N data element. (aihw.gov.au)
  • We conducted field investigations, advised on control measures and enhanced surveillance for skin and soft tissue infections at the school. (who.int)
  • Comparative Effectiveness of Antibiotic Treatment Strategies for Pediatric Skin and Soft-Tissue Infections. (medscape.com)
  • As a result, using any one antibiotic to treat a bacterial infection may result in other kinds of bacteria developing resistance to that specific antibiotic, as well as to other types of antibiotics. (mo.gov)
  • This study investigated the post invasive events upon S. aureus infection. (uni-wuerzburg.de)
  • The secondary endpoint was all invasive and surgical site S aureus infections through 90 days postoperation. (medscape.com)
  • Staphylococcus aureus is an opportunistic pathogen related to a variety of life-threatening infections but for which antimicrobial resistance is liming the treatment options. (nature.com)
  • Conclusions: Reduced disease severity of superficial infections due to both E. coli and S. aureus and resistance-driven prolonged stays in hospital were confirmed, while other outcome parameters were comparable. (scienceopen.com)
  • Our results demonstrate that many gene products contribute to the intrinsic antimicrobial resistance of S. aureus . (frontiersin.org)
  • Occurrence of high level methicillin resistance staphylococcus aureus. (who.int)
  • Staphylococcus aureus is a facultative Gram-positive human pathogen which can cause different severe infections. (uni-wuerzburg.de)
  • In this study, we identified the intrinsic resistome to a broad spectrum of antimicrobials in the human pathogen, Staphylococcus aureus . (frontiersin.org)
  • Subject Characteristics (cases with skin and soft tissue infection and controls) . (emory.edu)
  • Skin infections are common, but the bacteria can spread through the bloodstream and infect distant organs. (merckmanuals.com)
  • Skin infections may cause blisters, abscesses, and redness and swelling in the infected area. (merckmanuals.com)
  • Folliculitis and Skin Abscesses Folliculitis and skin abscesses are pus-filled pockets in the skin resulting from bacterial infection. (merckmanuals.com)
  • Most cases are sporadic skin and soft-tissue infections (SSTIs) with occasional clusters occurring in domestic settings. (who.int)
  • We describe an outbreak of skin abscesses caused by Panton-Valentine leukocidin -producing methicillin -susceptible S. aureus (clonal complex 121) in a professional rugby team in France during July 2010-February 2011. (bvsalud.org)
  • Staphylococcus aureus (Staph) is a common bacterium that is present in the nose or on the skin of about one quarter of healthy adults at any given time. (massgeneral.org)
  • Staphylococcus aureus is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. (wikipedia.org)
  • Although S. aureus usually acts as a commensal of the human microbiota, it can also become an opportunistic pathogen, being a common cause of skin infections including abscesses, respiratory infections such as sinusitis, and food poisoning. (wikipedia.org)
  • An estimated 21% to 30% of the human population are long-term carriers of S. aureus, which can be found as part of the normal skin microbiota, in the nostrils, and as a normal inhabitant of the lower reproductive tract of females. (wikipedia.org)
  • We asked six experts-people who have to deal with icky skin infections and issues on a daily basis-to give us the low-down on what's hanging around the gym, plus their tried-and-true methods for treating and avoiding infections in the first place. (greatist.com)
  • Five reports are current or updated, namely, those on catheter-associated urinary tract and surgical wound infections, isolation precautions in hospitals, infection control in hospital personnel, and handwashing and hospital environmental control. (cdc.gov)
  • In 1880, Alexander Ogston, a Scottish surgeon, discovered that Staphylococcus can cause wound infections after noticing groups of bacteria in pus from a surgical abscess during a procedure he was performing. (wikipedia.org)
  • S aureus carriers have a 2- to 9-fold increased risk of the development of a surgical-site or intravenous catheter infection. (johnshopkins.edu)
  • The S aureus surgical-site infection rate was not reduced significantly, but carriers who received mupirocin before cardiothoracic or general surgery operations had almost 50% fewer S aureus surgical-site infections than carriers who received placebo. (johnshopkins.edu)
  • Surgical providers should be cognizant that infections in this population are inevitable, and numerous studies prove the use of broader spectrum agents or prolonging prophylactic therapy does not further mitigate infection risk. (medscape.com)
  • Standardized Infection Ratios, or SIR), and presents more detailed information on different types of surgical site infections. (oregon.gov)
  • There are things you can do to reduce your risk of getting a surgical site infection. (oregon.gov)
  • Escherichia coli and Staphylococcus aureus are important causes of severe diseases like blood stream infections. (scienceopen.com)
  • Healthcare-associated infections can lead to the need for stronger or more antibiotics, more treatments, more days in the hospital, more cost for the patient and the hospital, and even severe complications or death. (oregon.gov)
  • Then, in 1884, German scientist Friedrich Julius Rosenbach identified Staphylococcus aureus, discriminating and separating it from Staphylococcus albus, a related bacterium. (wikipedia.org)
  • In the early 1930s, doctors began to use a more streamlined test to detect the presence of an S. aureus infection by the means of coagulase testing, which enables detection of an enzyme produced by the bacterium. (wikipedia.org)
  • 2001) revealed that approximately 22% of the S. aureus genome is non-coding and thus can differ from bacterium to bacterium. (wikipedia.org)
  • Staphylococcus aureus has long been recognized as an important pathogen in human disease and is the most common cause of nosocomial infections. (johnshopkins.edu)
  • Details of the patient's history aid in differentiating a common cold from conditions that require targeted therapy, such as group A streptococcal pharyngitis , bacterial sinusitis, and lower respiratory tract infections. (medscape.com)
  • In managing a septic prosthetic failure, the goals are to eradicate the infection and to provide a functional limb. (medscape.com)
  • Foot infections are a major cause of morbidity in people with diabetes and the most common cause of diabetes-related hospitalization and lower extremity amputation. (biomedcentral.com)
  • Health care-related infections cause significant patient morbidity and mortality rates and add excess costs that frequently are not reimbursed. (johnshopkins.edu)
  • Getting treatment for endocarditis right away improves the chances of clearing the infection and preventing complications. (medlineplus.gov)
  • This undermines the effectiveness of the available treatment options and thus contributes to the persistence of microbial infections. (who.int)
  • To elucidate the potential of the screen, we examined treatment efficacy in the Galleria mellonella infection model. (frontiersin.org)
  • However, efflux pumps inhibitors have not yet been approved for treatment of human infections due to tolerability issues ( Fernebro, 2011 ). (frontiersin.org)
  • Cite this: Prophylaxis and Treatment of Infections Associated with Penetrating Traumatic Injury - Medscape - Jan 01, 2011. (medscape.com)
  • The Tsukayama classification of arthroplasty-associated infection into four types (see Classification ) can help in formulating the treatment recommendations for the infection. (medscape.com)