• New Zealand has among the highest reported incidence of infections with the bacterium Staphylococcus aureus in the developed world. (cmrf.org.nz)
  • These infections are often recurrent and increasing numbers are being caused by strains like methicillin-resistant Staphylococcus aureus (MRSA), which are resistant to nearly all known antibiotics. (cmrf.org.nz)
  • What is Staphylococcus aureus? (cmrf.org.nz)
  • Staphylococcus aureus is a Gram-positive, round-shaped bacterium that is a member of the Firmicutes, and it is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. (cmrf.org.nz)
  • Here, we investigated the effect of PYED-1 on the biofilms of Staphylococcus aureus, an etiological agent of biofilm-based chronic infections such as osteomyelitis, indwelling medical device infections, periodontitis, chronic wound infections, and endocarditis. (unina.it)
  • The findings demonstrated that the LAB-CFS treatment considerably slowed Staphylococcus aureus ( S. aureus ) growth and prevented it from forming biofilms. (frontiersin.org)
  • One of the most prevalent foodborne infections, Staphylococcus aureus ( S. aureus ), is highly dangerous and endangers both human and animal health ( 1 ). (frontiersin.org)
  • Coagulase-negative staphylococci are gram-positive, aerobic organisms distinguished from the closely related Staphylococcus aureus by the group's inability to form coagulase, an enzyme that promotes thrombus formation via the conversion of fibrinogen into fibrin [2]. (dermnetnz.org)
  • The effects of these NPs on Acinetobacter baumannii , Staphylococcus aureus , and Escherichia coli biofilms were studied using quantitative biofilm inhibition and disruption assays, as well as using fluorescence, -scanning electron microscopy, and atomic force microscopy. (dovepress.com)
  • Acinetobacter baumannii , Staphylococcus aureus and Klebsiella pneumoniae . (labmanager.com)
  • Effectiveness of honey on Staphylococcus aureus and Pseudomonas aeruginosa biofilms. (microbiologyresearch.org)
  • Associated topics: sore-/-scratchy-throat - "The antibacterial activity of 14 essential oils and their major constituents in the gaseous state was evaluated against [respiratory tract pathogens] Haemophilus influenzae, Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus. (oil-testimonials.com)
  • MELBOURNE, Florida, February 7, 2008-- QuoNova LLC, which is 88.7% owned by XL TechGroup, Inc., has generated preliminary in-vitro data indicating high efficacy of selected Quorum Sensing Blockers ("QSB") in inhibiting biofilm formation by MRSA (methicillin-resistant Staphylococcus aureus) strains and fungal organisms such as Candida sp. (blogspot.com)
  • In this study, we screened a library of sphingosine-1-phosphate receptor (S1PR) modulators against Staphylococcus aureus and identified five active compounds. (helsinki.fi)
  • Candida albicans and Staphylococcus aureus , representing two different kingdoms, are the most frequently isolated pathogens from invasive infections. (mdpi.com)
  • Staphylococcus aureus merupakan salah satu bakteri yang dapat membentuk biofilm dan merupakan salah satu penyebab RSK. (ub.ac.id)
  • Pembentukan biofilm Staphylococcus aureus melalui 4 tahap yaitu tahap perlekatan, quorum sensing (QS), maturasi dan pelepasan, QS merupakan tahap paling penting pada proses pembentukan biofilm. (ub.ac.id)
  • Pada Staphylococcus aureus komunikasi diperantarai oleh sinyal mikromolekul autoinducer peptide (AIP). (ub.ac.id)
  • Propolis menghambat pertumbuhan Staphylococcus aureus, Staphylococcus epidermidis, Entero-coccus Sp. (ub.ac.id)
  • Malang Indonesia sebagai QSI pada isolat biofilm Staphylococcus aureus dari RSK berdasarkan penurunan AIP, histidine kinase, ekspresi gen agr dan morfologi biofilm. (ub.ac.id)
  • Pertama, Isolasi dan karakterisasi Staphylococcus aureus dan Eksplorasi dosis EEP Trigona Sp. (ub.ac.id)
  • Malang Indonesia sebagai QSI pada isolat biofilm Staphylococcus aureus dari RSK. (ub.ac.id)
  • Penelitian tahap pertama telah dilakukan isolasi dan karakterisasi Staphylococcus aureus. (ub.ac.id)
  • Kultur Congo Red didapatkan biofilm Staphylococcus aureus berwarna hitam. (ub.ac.id)
  • Tes kepekaan antibiotika Staphylococcus aureus multiresisten terhadap antibiotika. (ub.ac.id)
  • Pada tes ini Staphylococcus aureus resisten terhadap Cefoxitin (FOX), Vancomycin (VA), Oxacillin (OX), Penicillin (P), Erythromycin (E) dan Lincomycin (MY). (ub.ac.id)
  • Propolis exhibits antimicrobial effects on Escherichia coli and Staphylococcus aureus strains resistant to various antibiotics and some microorganisms. (pakalertpress.com)
  • Pseudomonas aeruginosa and Staphylococcus aureus causes severe infections, especially in nosocomial environments. (sasm.org.za)
  • 2015. Nisin incorporated with 2,3-dihydroxybenzoic acid in nanofibers inhibits biofilm formation by a methicillin-resistant strain of Staphylococcus aureus . (sasm.org.za)
  • Cell-free extracts isolated from colony biofilms of Actinobacillus pleuropneumoniae serotype 5 were found to inhibit biofilm formation by Staphylococcus aureus, S. epidermidis and Aggregatibacter actinomycetemcomitans, but not by A. pleuropneumoniae serotype 5 itself, in a 96-well microtiter plate assay. (vt.edu)
  • In this study, our goal was to assess the in vitro antimicrobial, anti-adhesive and anti-biofilm abilities of BS produced by Lactobacillus jensenii and Lactobacillus rhamnosus against clinical Multidrug Resistant (MDR) strains of Acinetobacter baumannii , Escherichia coli , and Staphylococcus aureus (MRSA). (biomedcentral.com)
  • Staphylococcus aureus is a gram positive, commensal bacteria found in normal human flora on the skin and mucous membranes. (randox.com)
  • Methicillin-resistant Staphylococcus aureus (MRSA) was first identified only one year after the introduction of the penicillin-like antibiotic, methicillin 3 . (randox.com)
  • Staphylococcus aureus is an opportunistic pathogen related to a variety of life-threatening infections but for which antimicrobial resistance is liming the treatment options. (nature.com)
  • Staphylococcus aureus is an important human opportunistic pathogen involved in a wide range of human infections. (nature.com)
  • . I t can inhibit biofilm formation and destroy existing biofilms of Staphylococcus aureus , which is a close relative, but is considered a pathogen. (esseskincare.co.uk)
  • The emergence of antibiotic-resistant strains of S. aureus such as methicillin-resistant S. aureus (MRSA) is a worldwide problem in clinical medicine. (cmrf.org.nz)
  • Since our system doesn't kill ''S. aureus'' but only prevents it from becoming pathogenic, it is less likely to promote the development of resistant strains. (igem.org)
  • Any drug impairing crucial processes for bacterial life will inevitably lead to the development of drug-resistant strains, whereas the inhibition of biofilm formation might prevent the onset of bacterial resistance. (intechopen.com)
  • In this section, we will focus on proteins involved in biofilm formation as useful targets for the development of new drugs that can effectively and specifically impair biofilm formation with slight effects on cell survival, thus avoiding the generation of drug-resistant strains. (intechopen.com)
  • Furthermore, their individual effects and synergistic potential in combination with antibiotics were examined against clinical strains of both S. aureus and Acinetobacter baumannii . (biomedcentral.com)
  • It also displayed a potent activity against other Gram-positive bacteria, including penicillin- and methicillin-resistant S. aureus strains, S. epidermidis, and Enterococcus faecalis, with a minimum inhibitory concentration (MIC) ranging from 5 to 10 mu M (2.3-4.6 mu g/mL). (helsinki.fi)
  • A number of plant oil extracts inhibit multi-resistant strains of bacteria and yeast . (pakalertpress.com)
  • In this study, two Lactobacillus (LAB) strains namely, Lactobacillus rhamnosus EMCC 1105 ( L. rhamnosus ) and Lactobacillus gasseri EMCC 1930( L. gasseri) were tested for their antagonistic activities against Pseudomonas aeruginosa ( P. aeruginosa ), Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) which are known to be frequently implicated in biofilm infections. (lifescienceglobal.com)
  • Both LAB strains could effectively inhibit the biofilm formation of the three test pathogens and largely replaced them on polystyrene surfaces as demonstrated by crystal violet staining, viable count and scanning electron microscopy. (lifescienceglobal.com)
  • Both of the tested LAB strains could inhibit the protease productivity of S. aureus in 24 h and 48 h dual species-biofilms. (lifescienceglobal.com)
  • This study aims to make inhibitors of the bacterial enzymes that make menaquinone to study how menaquinone affects biofilm formation which will lead to drugs to target and treat S. aureus infections and biofilms. (cmrf.org.nz)
  • Although S. aureus usually acts as a commensal of the human microbiota it can also become an opportunistic pathogen, being a common cause of skin infections including abscesses, respiratory infections such as sinusitis, and food poisoning. (cmrf.org.nz)
  • These results indicated that PYED-1 may have great potential as an effective antibiofilm agent to prevent S. aureus biofilm-associated infections. (unina.it)
  • These findings show that LAB-CFS has a strong potential to combat S. aureus infections. (frontiersin.org)
  • The capacity of S. aureus to build biofilms is correlated with the severity of infections ( 4 ). (frontiersin.org)
  • Now, with the increasing use of implanted medical equipment, they have become leading pathogens for nosocomial infections owing to their ability to form biofilms on foreign material [1,2]. (dermnetnz.org)
  • Therapeutic failures of antibiotics used to treat macrolide-susceptible Streptococcus pyogenes infections may be due to biofilm formation. (microbiologyresearch.org)
  • Cranberry may reduce the risk of urinary tract infections by inhibiting biofilms in the bladder. (pakalertpress.com)
  • The cells are often deeply imbedded in biofilms, which makes treatment of the infections extremely difficult. (sasm.org.za)
  • The presence of biofilms causes numerous problems in the field of medicine, interfering with clinical therapy of chronic and wound-related infections as well as persistent infections of various indwelling medical devices [ 15 ]. (biomedcentral.com)
  • In conclusion, L. gasseri and L. rhamnosus can be considered as promising tools for combating biofilm infections. (lifescienceglobal.com)
  • Biofilms have great importance for public health because of their role in certain infectious diseases and importance in a variety of device-related infections. (cdc.gov)
  • Propolis mampu menghambat pembentukan biofilm dengan cara mendegradasi extracellular polymeric substance (EPS), mengurangi motilitas bakteri Pseudomonas aeruginosa dan mengacaukan fungsi autoinducer AHL. (ub.ac.id)
  • 2014. 2,3-Dihydroxybenzoic acid-containing nanofiber wound dressings inhibits biofilm formation by Pseudomonas aeruginosa . (sasm.org.za)
  • Transcriptional analysis performed on the established biofilm revealed that PYED-1 downregulates the expression of genes related to quorum sensing (agrA, RNAIII, hld, psm, and sarA), surface proteins (clfB and fnbB), secreted toxins (hla, hlb, and lukD), and capsular polysaccharides (capC). (unina.it)
  • In conclusion, PYED-1 not only effectively inhibited biofilm formation, but also eradicated preformed biofilms of S. aureus, modulating the expression of genes related to quorum sensing, surface and secreted proteins, and capsular polysaccharides. (unina.it)
  • We have [https://2009.igem.org/Team:SDU-Denmark/Background#Quorum-quenching_using_RIP reason to hope] that this will weaken the biofilm formation, thereby making multiresistant bacteria easier to treat with conventional antibiotics. (igem.org)
  • On the other hand we know that a higher concentration of ''RIP'' is more efficient in quorum-quenching ''S. aureus'', and it will therefore be more efficient if the plasmid is transcribed at all times. (igem.org)
  • On the other hand, etrasimod was shown to inhibit quorum sensing (QS) signaling in Chromobacterium violaceum, suggesting that it may block the biofilm formation by targeting QS in certain Gram-negative bacteria. (helsinki.fi)
  • Quorum sensing Inhibitor (QSI) merupakan salah satu pendekatan strategis untuk pengembangan terapi baru pengobatan biofilm bakteri. (ub.ac.id)
  • Cells may also communicate via quorum sensing, which may in turn affect biofilm processes such as detachment. (cdc.gov)
  • The microbial community is also a natural source of metabolites and has the potential to be used to create antimicrobial and anti-biofilm agents. (frontiersin.org)
  • Thus, under optimal pH conditions, such as physiological pH, penetration of CIP into a biofilm is enhanced and pathogens are eradicated more effectively. (sasm.org.za)
  • Therefore, inhibiting the growth of oral pathogens, as well as effectively preventing biofilm formation contribute to reducing these risks. (biomedcentral.com)
  • The antimicrobial, anti-adhesive and anti-biofilm activities of both BS against the above mentioned MDR pathogens were determined. (biomedcentral.com)
  • Anti-adhesive and anti-biofilm activities were also observed for the aforementioned pathogens between 25 and 50 mg/ml. (biomedcentral.com)
  • While methicillin has lost its clinical utility due to the emergent resistance, MRSA is used to describe S. aureus which displays resistance to penicillin-like antibiotics such as amoxicillin and oxacillin, as well as other forms of commercially available antibiotics like macrolides, tetracyclines, and fluroquinolones 4 . (randox.com)
  • showed that 43% of S. aureus isolates where methicillin-resistant, exhibiting the prevalence of MRSA 5 . (randox.com)
  • AuNPs also showed biofilm inhibition, with the highest of 98% in S. aureus . (dovepress.com)
  • This is the first report on rapid and efficient synthesis of AgNPs, AuNPs and AgAuNPs from P. zeylanica and their effect on quantitative inhibition and disruption of bacterial biofilms. (dovepress.com)
  • Unlike antibacterials that aim to inhibit cell growth, antivirulence therapies are based on the inhibition of bacterial virulence. (nature.com)
  • During biofilm formation the bacteria sense a range of environmental cues and interpret these as signals to cluster. (cmrf.org.nz)
  • PYED-1 caused a strong reduction in biofilm formation in a concentration dependent manner. (unina.it)
  • Fibrinogen induces biofilm formation by Streptococcus suis and enhances its antibiotic resistance. (microbiologyresearch.org)
  • Biofilm formation requires three different stages: cell attachment to a solid substrate, adhesion, and growth. (intechopen.com)
  • Natural products have demonstrated different mechanisms of antimicrobial action, such as promoting cell wall rupture and lysis, inhibiting biofilm formation, preventing cell wall construction, interrupting microbial DNA replication, and inhibiting the synthesis of bacterial toxins to the host, among others [ 5 , 6 ]. (biomedcentral.com)
  • Biofilm formation was inhibited when cells were exposed to nanofibers containing Ciprofloxacin. (sasm.org.za)
  • Furthermore, polystyrene surfaces coated with A. pleuropneumoniae wild-type extracts, but not with capsule-mutant extracts, resisted S. aureus biofilm formation. (vt.edu)
  • Techniques to inhibit biofilm formation are essential and have wide applications. (biomedcentral.com)
  • In this study, we evaluated the ability of two types of biosurfactants (rhamnolipids and surfactin) to inhibit growth and biofilm formation ability of oral pathogenic bacteria such as Aggregatibacter actinomycetemcomitans , Streptococcus mutans , and Streptococcus sanguinis . (biomedcentral.com)
  • Rhamnolipids inhibited the growth and biofilm formation ability of all examined oral bacteria. (biomedcentral.com)
  • We also attempted to determine the step in the biofilm formation process that was inhibited by biosurfactants. (biomedcentral.com)
  • The results clearly demonstrated that rhamnolipids inhibit biofilm formation after the initiation process, however, they do not affect attachment or maturation. (biomedcentral.com)
  • Rhamnolipids inhibit oral bacterial growth and biofilm formation by A. actinomycetemcomitans Y4, and may serve as novel oral drug against localized invasive periodontitis. (biomedcentral.com)
  • Thus, there is a requirement for the development of a simpler and more effective oral care capable of inhibiting oral bacterial growth and biofilm formation. (biomedcentral.com)
  • We report here that myricetin, but not its glycosylated form, can remarkably decrease the production of several S. aureus virulence factors, including adhesion, biofilm formation, hemolysis and staphyloxanthin production, without interfering with growth. (nature.com)
  • Two major thrusts in the last decade have dramatically impacted our understanding of biofilms: the utilization of the confocal laser scanning microscope to characterize biofilm ultrastructure, and an investigation of the genes involved in cell adhesion and biofilm formation. (cdc.gov)
  • Sublethal concentrations of manuka honey effectively prevented the binding of S. pyogenes to the human tissue protein fibronectin, but did not inhibit binding to fibrinogen. (microbiologyresearch.org)
  • Streptococcus mutans , a representative bacteria of tooth decay [ 10 ], forms plaques (biofilm) on tooth surfaces and produces lactate from sugars such as sucrose, which demineralizes teeth and causes dental caries. (biomedcentral.com)
  • Streptococcus sanguinis is another plaque-forming strain that has been reported to cause infective endocarditis by forming biofilms on the endocardium and heart valves [ 11 ]. (biomedcentral.com)
  • Purified serotype 5 capsular polysaccharide also exhibited antibiofilm activity against S. aureus. (vt.edu)
  • Biofilms are conglomerations of bacterial cells protected by self-synthesized extracellular polysaccharide matrices (EPS). (biomedcentral.com)
  • By using a specific polysaccharide-stain called Ruthenium red and coupling this with osmium tetroxide fixative, these researchers were also able to show that the matrix material surrounding and enclosing cells in these biofilms was polysaccharide. (cdc.gov)
  • These NPs also showed antimicrobial and antibiofilm activity against E. coli , A. baumannii , S. aureus , and a mixed culture of A. baumannii and S. aureus . (dovepress.com)
  • BS of both L. jensenii and L. rhamnosus showed antimicrobial activities against A. baumannii , E. coli and S. aureus at 25-50 mg/ml. (biomedcentral.com)
  • Both BS also displayed anti-adhesive and anti-biofilm abilities against A. baumannii , E. coli and S. aureus . (biomedcentral.com)
  • This study focused on the changes in biofilm activity and related metabolic pathways of S. aureus treated with lactic acid bacteria planktonic CFS (LAB-pk-CFS) and biofilm state (LAB-bf-CFS). (frontiersin.org)
  • However, there have not been many investigations on how pathogenic bacteria are affected by the metabolic properties of planktonic and biofilm probiotics. (frontiersin.org)
  • Here, we used untargeted metabolomics to investigate the potential impacts of planktonic bacteria (LAB-pk-CFS) and biofilm colonies (LAB-bf-CFS) on the metabolism of S. aureus biofilms. (frontiersin.org)
  • In this study, the effect of manuka honey on S. pyogenes (M28) was investigated in vitro with planktonic and biofilm cultures using MIC, MBC, microscopy and aggregation efficiency. (microbiologyresearch.org)
  • Bactericidal effects were found in both planktonic cultures and biofilms, although higher concentrations of manuka honey were needed to inhibit biofilms. (microbiologyresearch.org)
  • Bacteria can be found in planktonic form or in specific conditions, as sessile aggregates on both biotic and abiotic surfaces originating complex structures known as biofilm. (intechopen.com)
  • Among them, etrasimod (APD334), an investigational drug for the treatment of ulcerative colitis, displayed the best inhibitory activity against S. aureus when growing as free-floating planktonic cells and within biofilms. (helsinki.fi)
  • Anti-bacterial agents and disinfectants are effective against planktonic bacteria (bacteria suspended in liquid), however, they are not effective against biofilm-forming bacteria due to the difficulty of chemicals penetrating the biofilm. (biomedcentral.com)
  • Considered generally recognized as safe (GRAS) by the Food and Drug Administration and recently approved by the U.S. Dept. of Agriculture for use on fresh beef, ALF can be sprayed onto carcasses to help prevent bacterial contamination during processing or can be applied to a subprimal or finished beef surface prior to final packaging to inhibit bacterial growth and extend shelf life. (ift.org)
  • A. pleuropneumoniae wild-type extracts did not inhibit S. aureus growth, but did inhibit S. aureus intercellular adhesion and binding of S. aureus cells to stainless steel surfaces. (vt.edu)
  • Biofilm is a complex matrix consisting of extracellular polysaccharides, DNA, and proteins that protect bacteria from a variety of physical, chemical, and biological stresses allowing them to survive in hostile environments. (intechopen.com)
  • Biofilms are three-dimensional structures consisting of various microbial populations attached to a surface by extracellular polymeric substances (EPS) produced by these microorganisms [ 1 ]. (biomedcentral.com)
  • Biofilm-associated cells can be differentiated from their suspended counterparts by generation of an extracellular polymeric substance (EPS) matrix, reduced growth rates, and the up- and down- regulation of specific genes. (cdc.gov)
  • A biofilm is an assemblage of surface-associated microbial cells that is enclosed in an extracellular polymeric substance matrix. (cdc.gov)
  • GAS) is always of clinical significance in wounds where it can initiate infection, destroy skin grafts and persist as a biofilm. (microbiologyresearch.org)
  • However, given the opportunity to colonise internal tissues or the bloodstream, S. aureus infection can cause serious disease. (randox.com)
  • These promising results, which are the subject of continuing research, further underscore the potential of QuoNova's QSB in combating the detrimental effects of biofilms, especially in clinical environments, where mixed microbial communities predominate. (blogspot.com)
  • Bacteria survive in various environments by forming biofilms. (biomedcentral.com)
  • Since that time, the studies of biofilms in industrial and ecologic settings and in environments more relevant for public health have basically paralleled each other. (cdc.gov)
  • Extracts and phases obtained from the medicinal plant M. albicans demonstrated synergistic effects when combined with the commercial antibiotics ampicillin and ciprofloxacin, against multi-drug resistant bacteria S. aureus and A. baumannii , restoring their antibacterial efficacy. (biomedcentral.com)
  • Extracts and phases also exhibited antibiofilm property against S. aureus . (biomedcentral.com)
  • AgNPs also showed good biofilm disruption, with the highest of 88% in A. baumannii . (dovepress.com)
  • Finally, analysis by electron microscope indicated that the BS caused membrane damage for A. baumannii and pronounced cell wall damage in S. aureus . (biomedcentral.com)
  • By electrospinning Ciprofloxacin into a nanofiber scaffold consisting of poly(D,L-lactide) (PDLLA) and poly(ethylene oxide) (PEO), the antibiotic was released within 2 h, killing 99% of P. aeruginosa and 91% of a methicillin-resistant strain of S. aureus in a biofilm. (sasm.org.za)
  • Cells in a biofilm are often exposed to sub-lethal concentrations of antibiotics and may develop resistance in a relatively short period. (sasm.org.za)
  • Antibiotic-filled nanofibers may be the answer to the eradication of P. aeruginosa and S. aureus biofilms. (sasm.org.za)
  • Most of the antibiotic was released from the nanofibers within 2 h and almost all cells of P. aeruginosa and S. aureus were killed during this period. (sasm.org.za)
  • Additionally, it inhibits the physiological traits of the S. aureus biofilm, including hydrophobicity, motility, eDNA, and PIA associated to the biofilm. (frontiersin.org)
  • S. aureus produces large biofilm formations that support its pathogenicity and confer protection and subsequently drug resistance ( 5 ). (frontiersin.org)
  • The present findings reveal the potential of Myr as an alternative multi-target antivirulence candidate to control S. aureus pathogenicity. (nature.com)
  • Biofilms are an ensemble of microbial cells irreversibly associated with a surface and enclosed in an essentially self-produced matrix. (intechopen.com)
  • An established biofilm structure comprises microbial cells and EPS, has a defined architecture, and provides an optimal environment for the exchange of genetic material between cells. (cdc.gov)
  • This information is crucial for the clinical diagnosis, care, and prevention of S. aureus . (frontiersin.org)
  • The biofilm matrix consists of polysaccharides, proteins, and DNA and constitutes a stubborn source that protects bacteria from a variety of physical, chemical, and biological stresses. (intechopen.com)
  • The differentially expressed genes and proteins linked to S. aureus biofilms have been identified using transcriptomic and proteomic investigations ( 14 - 17 ). (frontiersin.org)
  • Aggregatibacter actinomycetemcomitans has been strongly associated with localized aggressive periodontitis via its ability to form biofilms in the subgingival cavity [ 12 ]. (biomedcentral.com)
  • Microorganisms attach to surfaces and develop biofilms. (cdc.gov)
  • Rediscovery of a microbiologic phenomenon, first described by van Leeuwenhoek, that microorganisms attach to and grow universally on exposed surfaces led to studies that revealed surface-associated microorganisms (biofilms) exhibited a distinct phenotype with respect to gene transcription and growth rate. (cdc.gov)
  • These biofilm microorganisms have been shown to elicit specific mechanisms for initial attachment to a surface, development of a community structure and ecosystem, and detachment. (cdc.gov)
  • Van Leeuwenhoek, using his simple microscopes, first observed microorganisms on tooth surfaces and can be credited with the discovery of microbial biofilms. (cdc.gov)
  • 5 ) in 1978 put forth a theory of biofilms that explained the mechanisms whereby microorganisms adhere to living and nonliving materials and the benefits accrued by this ecologic niche. (cdc.gov)
  • The observations were largely in concordance with the biofilm assay results. (biomedcentral.com)
  • To corroborate these results, biofilms were observed by scanning electron microscopy (SEM) and confocal microscopy. (biomedcentral.com)
  • Manuka honey permeated 24 h established biofilms of S. pyogenes, resulting in significant cell death and dissociation of cells from the biofilm. (microbiologyresearch.org)
  • This is helped by their ability to make biofilms, where they adhere together on a surface. (cmrf.org.nz)
  • 3 ) used scanning and transmission electron microscopy to examine biofilms on trickling filters in a wastewater treatment plant and showed them to be composed of a variety of organisms (based on cell morphology). (cdc.gov)
  • Much of the work in the last 2 decades has relied on tools such as scanning electron microscopy (SEM) or standard microbiologic culture techniques for biofilm characterization. (cdc.gov)
  • Diffusion of Ciprofloxacin into the biofilm depended on the net charge of the biofilm. (sasm.org.za)
  • 2014. 2,3- dihydroxybenzoic acid electrospun into poly (D, L-lactide)(PDLLA)/poly (ethylene oxide)(PEO) nanofibers inhibited the growth of Gram-positive and Gram-negative bacteria . (sasm.org.za)
  • Our findings suggest that the A. pleuropneumoniae serotype 5 capsule inhibits cell-to-cell and cell-to-surface interactions of other bacteria. (vt.edu)