Attacks connective tissue diseases. Medical search. Frequent questions

Rheumatoid arthritis - Rheumatoid arthritis is a systemic disorder in which immune cells attack and inflame the membrane around joints. (wikipedia.org)
In a study published in December, 2020 in Arthritis and Rheumatology, researchers compared the COVID-19 outcomes of patients with systemic autoimmune rheumatic diseases (SARDs) such as Sjögren's (317), lupus (528), rheumatoid arthritis (1,181), to non-SARD patients with COVID-19. (sjogrenscanada.org)
Examples of autoimmune conditions include the following: Rheumatoid arthritis (RA) Type 1 diabetes Crohn's Disease Hashimoto's thyroiditis Neurological diseases Multiple Sclerosis (MS) Glomerulanephritis Pernicious Anaemia Goodpasture's syndrome Scleroderma Raynaud's Phenomenon Lupus (e.g., systemic lupus erythematosus [SLE]) Inflammatory bowel disease (IBD). (ecopolitan.com)
There are many of these auto-antibody-producing diseases, including rheumatoid arthritis and connective tissue diseases like lupus, systemic sclerosis and overlapping connective tissue diseases. (gc.ca)
The autoimmune disease that leads to the inflammation of the membranes of the joints is known as Rheumatoid arthritis. (integrativetelemedicine.com)
Sjogren's Syndrome is a chronic disease of the connective tissues that occurs in 31% of people with rheumatoid arthritis. (integrativetelemedicine.com)
Two additional diseases, Rheumatoid Arthritis and Sjogren's Disease, may also contribute their symptoms to the overall clinical picture. (mctdfoundation.org)
Most rheumatic diseases are treated with analgesics, NSAIDs, steroids, Disease-Modifying Anti-Rheumatic Drugs, monoclonal antibodies, such as infliximab and adalimumab, and the soluble TNF receptor etanercept and Methotrexate for moderate to severe Rheumatoid arthritis. (scitechnol.com)
Rheumatoid arthritis is related with the immune system that leads to inflammation in the joints of the body, and later on the disease affects the muscles, fibrous tissues, tendons, and connective tissues. (express-press-release.net)
The load of rheumatoid arthritis (RA), currently incurable and an unending autoimmune disease that basically attacks the joints, is prominent. (express-press-release.net)
Rheumatoid Arthritis (RA) Arthritis is a group of diseases that makes your joints hurt, swell up, and turn red. (msdmanuals.com)
Common use cases include rheumatoid arthritis, ulcerative colitis, connective tissue disease, and organ transplants. (northwestpharmacy.com)
Increased CH 50 , C3, and C4 values may occur in the context of systemic inflammation as complement proteins are synthesized as part of the acute-phase response in connective-tissue diseases including, but not limited to, SLE and rheumatoid arthritis (RA), severe bacterial and viral infections, and other diseases such as cancer, diabetes mellitus, and myocardial infarction. (medscape.com)

Scleroderma - an activation of immune cells that produces scar tissue in the skin, internal organs, and small blood vessels. (wikipedia.org)
Connective tissue provides the framework and support for tissues throughout the body, including bones, muscles, blood vessels, and organs. (medicalnewstoday.com)
Scleroderma is a connective tissue disease that is a type of autoimmune disorder causing changes in skin, muscle, blood vessels and internal organs. (healthstatus.com)
Chemotaxis is the migration of white blood cells from the blood vessels in the connective tissue through healthy connective tissue and epithelium to the sulcus where they attack the bacteria. (dentistryiq.com)
Autoimmune diseases that attack the body's blood vessels, such as systemic lupus erythematosus and polyarteritis nodosa, also have been associated with SCAD. (ochsner.org)
Coronary artery disease is a common heart condition that affects the major blood vessels that supply the heart muscle. (mayoclinic.org)
Scleroderma is a group of diseases in which the skin hardens and causes issues in the blood vessels or digestive tract. (integrativetelemedicine.com)
Vasculitis is an autoimmune disease of the connective tissues, and inflammation of the blood vessels characterizes the disease. (integrativetelemedicine.com)
This type of connective tissue is used for blood vessels, nerves, lymphatic system, and so on. (no-carb-diet.com)

They evaluate and give treatment for people with health problems caused by injury, disease, or overuse of muscles or tendons. (wjmc.org)
Apart from problems in the joints themselves, people with inflammatory arthritis may have inflammation and discomfort in the tendons and the other soft tissues in the feet. (advancedregeneration.com)
These types of tissues include muscles, tendons, and ligaments. (scitechnol.com)

Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs. (wikipedia.org)
sufferers of scleroderma will experience a buildup of collagen in the skin and other organs and this is what leads to the symptoms of the disease. (healthstatus.com)
Another, more serious variant of the disease, is called Systemic scleroderma, or sclerosis, and can affect large areas of the skin as well as other organs such as the heart, lungs, and kidneys. (healthstatus.com)
Since this disease can affect various organs such as skin, muscle, the digestive system and lungs, as well as your joints, treatment is targeted to manage the major areas of involvement. (healthline.com)
MCTD occurs when your immune system attacks the connective tissue that provides the framework for the organs of your body. (healthline.com)
She battles lupus, the insidious disease that lurks and hides from detection as it destroys the body's connective tissue and attacks organs. (tucsonweekly.com)
In these cases, antibodies become biological missiles called auto-antibodies that attack our own cells and organs. (gc.ca)
Rheumatic diseases can also affect other areas of the body, such as internal organs. (wjmc.org)
Collagen vascular diseases are autoimmune diseases that occur when the body's immune system attacks its own skin, tissues and organs. (kyoto2.org)
Vasculitis does not only damage the skin but can also affect organs like the kidneys or the heart when the disease gets serious. (integrativetelemedicine.com)
As the immune system attacks these tissues, they become inflamed causing soreness, pain and in some instances damage to the organs. (mctdfoundation.org)
Rheumatic diseases can also affect other areas of the body, including organs. (scitechnol.com)
Some diseases may even damage other organs of the body, such as the kidneys, intestines, and heart. (impactphysiotherapy.ca)
Connective tissue is what holds your organs together. (msdmanuals.com)

Ehlers-Danlos syndromes - a heterogeneous group of disorders characterized by connective tissue fragility. (wikipedia.org)
Due to modifications to the 2017 hEDS diagnostic criteria, joint hypermobility (and associated joint complications) without other signs of a hereditary connective tissue disorder now classifies for a diagnosis of one of the hypermobility spectrum disorders. (wikipedia.org)
There are more than 200 of these conditions, including genetic disorders such as Ehlers-Danlos syndrome, autoimmune disorders such as scleroderma , and cancers such as soft tissue sarcomas . (medicalnewstoday.com)
75. What other diseases and disorders are commonly associated with mast cell disease? (mastattack.org)
GI disorders that specifically affect motility are also seen in mast cell disease, like gastroparesis and chronic intestinal pseudoobstruction. (mastattack.org)
Mast cell diseases have many symptoms that are also commonly found in other disorders. (mastattack.org)
It's believed that certain diseases, such as connective tissue disorders, hemochromatosis (the excessive buildup of iron in the body), and amyloidosis (the buildup of abnormal proteins), can cause cardiomyopathy. (everydayhealth.com)
Connective tissue diseases are disorders featuring abnormalities involving the collagen and elastin. (orthopedicshealth.com)
A rheumatologist, a doctor who specializes in rheumatic and autoimmune diseases, is commonly considered the expert in these disorders and is likely to perform a complete physical examination, keeping an eye out for swollen hands and painful, swollen joints as well as carefully listening and noting other symptoms the patient may be experiencing. (understandingmyositis.org)
Some signs, such as red skin at the base of the nails, can signify connective tissue disorders. (wikidoc.org)

Diseases that affect the function or structure of connective tissue are known as connective tissue diseases. (medicalnewstoday.com)
The diseases are known as connective tissue diseases. (scitechnol.com)

Elastin is the major component of ligaments (tissues that attach bone to bone) and skin. (wikipedia.org)
Collagen vascular disease, also known as connective tissue disease, is a group of autoimmune diseases that attack the connective tissues in the body that hold muscles, ligaments, and bones together. (kyoto2.org)
Next, your physiotherapist will assess the stability of your joints to determine if there is any laxity of the ligaments or tissues of your joints. (impactphysiotherapy.ca)

The different types of autoimmune connective tissue diseases are discussed below. (integrativetelemedicine.com)
This page looks at the causes and different types of autoimmune disease in dogs. (dogzhealth.com)
This results in different types of autoimmune disease. (dogzhealth.com)

The causes and symptoms of connective tissue diseases are caused by gene defects vary as a result of what protein is abnormally produced by that defective gene. (born-wild.com)
The causes and symptoms of connective tissue diseases that are caused by an autoimmune disease vary from condition to condition. (born-wild.com)

Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues (autoimmunity). (wikipedia.org)
Sometimes, a person's immune system attacks their healthy cells and tissues. (medicalnewstoday.com)
In autoimmune connective tissue diseases, the immune system attacks healthy connective tissue, causing inflammation and damage. (medicalnewstoday.com)
Like psoriasis, it appears to be related to the immune system, where for reasons that remain unknown, your immune system attacks your own healthy cells. (health.am)
SARDs are diseases where the immune system attacks connective tissues. (sjogrenscanada.org)
It's an autoimmune disorder , meaning it involves your immune system mistakenly attacking healthy tissue. (healthline.com)
Steroid medications, such as prednisone , can treat inflammation and help stop your immune system from attacking healthy tissues. (healthline.com)
This is where we will see the immune response in action and the start of connective tissue breakdown associated with periodontal disease. (dentistryiq.com)
A healthy immune system is able to keep the tissue destruction and tissue repair in balance. (dentistryiq.com)
Polymyalgia is believed to be a disease in which the body's immune system attacks connective tissues. (bondclinic.com)
Systemic autoimmune rheumatic diseases (SARDs) are a family of arthritic conditions in which people's normally protective immune systems are misled and react against themselves. (gc.ca)
This is defined as where foreign substances, here silicone, present or injected into the body creates an immune response, usually some sort of collagen vascular disease. (jromano.com)
It is an autoimmune disease in which the immune system runs amok, attacking joints and connective tissue as if they were foreign invaders. (besthealthmag.ca)
This means the body's immune system attacks its own healthy cells and tissues. (wjmc.org)
Treatment of mixed connective tissue disease is directed at suppressing immune-related inflammation of tissues. (orthopedicshealth.com)
Connective tissue diseases are often characterized by a variety of immune abnormalities that are common for each particular type of illness. (orthopedicshealth.com)
In this autoimmune disease, the immune system attacks fluid-producing areas of the body, such as the tear ducts, and salivary glands. (integrativetelemedicine.com)
MCTD is an autoimmune disease which occurs when a person's immune system decides to ramp up and fight against the enemy…YOU. (mctdfoundation.org)
Lupus results from the body's immune system making a mistake and attacking the body's own cells. (sciencenews.dk)
Other types of diseases are caused by the body immune system attacking its own healthy cells and tissues. (scitechnol.com)
In October 2020, Johnson & Johnson announced successful acquisition of Momenta Pharmaceuticals, Inc. ("Momenta"), a company that discovered and developed novel therapies for immune-mediated diseases. (express-press-release.net)
A utoimmune disease refers to conditions in which the immune system does not work properly. (dogzhealth.com)
Autoimmunity is an improper immune response that occurs when the immune system reacts to the wrong proteins and attacks the body itself. (dogzhealth.com)
This is a blood disease in which the immune system launches an autoimmune response against the body's red blood cells. (dogzhealth.com)
Immune-mediate arthritis is a group of diseases in which antibodies attack the dog's own connective tissue. (dogzhealth.com)
The immune system's job is to attack things that don't belong in your body, including: Germs. (msdmanuals.com)
Autoimmune Diseases The immune system is your body's defense system. (msdmanuals.com)
The immune system usually attacks invading bacteria, viruses, and cancer cells. (msdmanuals.com)
your immune system makes a mistake and starts attacking parts of your own body. (msdmanuals.com)
An autoimmune disorder of connective tissue is a disease in which your immune system attacks your own connective tissue. (msdmanuals.com)
The integration of pathogen-associated molecular patterns (PAMPs) from microorganisms with their surface receptors in the immune cells, induces the production of several cytokines and chemokines that presents either a pro- and/or anti-inflammatory role by stimulating the secretion of a great variety of antibody subtypes and the activation of mechanisms of controlling the disease, such as the regulatory T cells. (bvsalud.org)
Although several studies have tried to clarify some of the immune mechanisms involved in periodontal disease, more studies must be conducted to understand its development and progression and consequently to discover new alternatives for the prevention and treatment of this severe inflammatory disease. (bvsalud.org)
However, the immune response initiated by periodontal disease seems to be much broader. (bvsalud.org)
Therefore, this review summarizes some immune mechanisms involved in periodontal disease. (bvsalud.org)

The classic collagen vascular diseases include: Systemic lupus erythematosus (SLE) - An inflammation of the connective tissues, SLE can afflict every organ system. (wikipedia.org)
Systemic lupus erythematosus is a chronic autoimmune disease that causes inflammation of the connective tissue. (sciencenews.dk)

In 2017, there were 3,046 deaths due to rheumatic valvular heart disease and 24,811 deaths due to non-rheumatic valvular heart disease in the United States. (cdc.gov)
Nearly 25,000 deaths in the U.S. each year are due to heart valve disease from causes other than rheumatic disease. (cdc.gov)
Rheumatic disease can happen after an infection from the bacteria that causes strep throat is not treated with antibiotics. (cdc.gov)
Increasing understanding of systemic autoimmune rheumatic diseases (SARDs), and developing, testing and disseminating interventions to improve the quality of life of people affected. (gc.ca)
Dr. Paul R. Fortin, Canada Research Chair in Systemic Autoimmune Rheumatic Diseases, has been working to better understand the bio-psycho-social impact of chronic rheumatic diseases associated with SARDs. (gc.ca)
In the 1990's concerns built regarding a potential association between silicone and autoimmune or rheumatic diseases, and the FDA issued a moratorium that severely limited use of silicone breast implants. (jromano.com)
The term comprises more than 100 different rheumatic diseases that cause pain, swelling, inflammation, and impaired movement in joints and connective tissue throughout the body. (besthealthmag.ca)
What is the difference between arthritis and other rheumatic diseases? (wjmc.org)
It is also a type of rheumatic disease. (wjmc.org)
Rheumatic diseases may cause pain, stiffness, and swelling in the joints. (wjmc.org)
Some rheumatic diseases affect connective tissues. (wjmc.org)
Who treats arthritis and other rheumatic diseases? (wjmc.org)
Your doctor or other healthcare providers may treat arthritis and other rheumatic diseases. (wjmc.org)
This team approach is especially important to help manage the symptoms of a rheumatic disease. (wjmc.org)
Some of the more common healthcare providers that help treat arthritis and other rheumatic diseases are listed below. (wjmc.org)
A rheumatologist is a doctor with special training to treat arthritis and other rheumatic diseases. (wjmc.org)
They are trained to find many types of rheumatic diseases in their earliest stages. (wjmc.org)
PTs help you live with arthritis and other rheumatic diseases. (wjmc.org)

A study that assessed microcapillary status and serum concentrations of chosen cytokines, adhesive molecules, and nitric oxide in pediatric patients with primary Raynaud syndrome and secondary Raynaud syndrome found that external factor-induced vasoconstrictive effects dominated in primary Raynaud syndrome, whereas in secondary Raynaud syndrome in the course of connective tissue diseases, it was accompanied by coexistent vasodilation due to endothelial dysfunction which was partially dependent on insufficient nitric oxide release. (medscape.com)

What diseases characteristically affect connective tissue? (orthopedicshealth.com)

Most, but not all, are due to a defect in the synthesis of collagen (Type I or III) and cause progressive deterioration of collagen, with different EDS types affecting different sites in the body, such as joints, heart valves, organ walls, arterial walls (due to where the affected connective tissue component is found throughout the body). (wikipedia.org)
Psoriatic arthritis is a chronic inflammatory disease of the joints and connective tissue. (health.am)
Diseases of connective tissue that are strictly inheritable (due to genetic inheritance) include Marfan syndrome (can have tissue abnormalities in the heart, aorta, lungs, eyes, and skeleton) and Ehlers-Danlos syndrome (may have loose, fragile skin or loose [hyperextensible] joints). (orthopedicshealth.com)
If systemic lupus erythematosus prevails, there may be trouble breathing, kidney disease, and/or arthritis of the joints. (understandingmyositis.org)
Many different diseases can result in inflammation of the joints. (impactphysiotherapy.ca)
Arthritis is therefore a general term that describes more than one hundred different diseases of the joints of your body. (impactphysiotherapy.ca)
The diseases that cause arthritis can also attack muscle and connective tissue around joints. (impactphysiotherapy.ca)
Due to the fact that the diseases inflame the joints, most arthritic conditions and related diseases involve chronic (long-term) pain. (impactphysiotherapy.ca)
Over time, they may cause increasing damage to the joints or soft tissues of your body. (impactphysiotherapy.ca)

Genetic diseases that cause problems with the body's connective tissues, such as vascular Ehlers-Danlos syndrome and Marfan syndrome, have been found to occur in people who have had SCAD. (ochsner.org)

Itching is medically known as pruritus, and autoimmune itching due to connective tissue disease is painful and can have a massive impact on a patient's life. (integrativetelemedicine.com)

Connective tissue disease, such as Ehlers-Danlos or Marfan syndrome. (upmc.com)
Ehlers Danlos Syndrome (EDS), is the most common connective tissue disease in the mast cell population. (mastattack.org)
For those of us with connective tissue diseases like Ehlers Danlos, we are always at a disadvantage. (mastattack.org)

Sometimes, a gene may change during or after pregnancy, resulting in a child having a sporadic genetic connective tissue disease when no family history of the condition exists. (medicalnewstoday.com)

This occurs when you're born with excess leaflet tissue, known as a "floppy mitral valve. (upmc.com)
is a condition which occurs when endometrial tissue, the tissue that lines the uterus and is shed during menstruation, grows outside the uterus. (ehso.com)
When a combination of symptoms of certain multiple autoimmune diseases occurs, it is referred to as a connective tissue disorder or "overlap disease. (understandingmyositis.org)
Release of damaged cells and tissue debris occurs upon injury. (medscape.com)
Progression of this disease occurs due to a combination of factors, including the presence of periodontopathic bacteria, high levels of proinflammatory cytokines, matrix metalloproteinases (MMPs), prostaglandin E2 (PGE2), low levels of anti-inflammatory cytokines including inter- leukin-10 (IL-10), transforming growth factor (TGF- β ) and tissue inhibitors of MMPs (TIMPs) (2,3). (bvsalud.org)

Scleroderma may occur in tangent with other autoimmune diseases such as systemic lupus erythematosus and polymyositis. (healthstatus.com)
Variations of this disease may affect only the skin of the hands and face, this is referred to as localized scleroderma. (healthstatus.com)
In contrast, secondary Raynaud phenomenon, especially when associated with scleroderma-related diseases, often causes irreversible digital ischemia, resulting in the development of digital ulcers or even digital amputation. (medscape.com)
Systemic inflammatory disease, such as scleroderma or lupus. (upmc.com)
Mixed connective tissue disease, as first described in 1972, is "classically" considered as an "overlap" of three diseases, systemic lupus erythematosus, scleroderma, and polymyositis. (orthopedicshealth.com)
Mixed connective tissue disease is classified and considered as an "overlap" of three diseases, Systemic Lupus Erythematosus, Scleroderma, and Polymyositis. (understandingmyositis.org)

Marfan syndrome - a genetic disease causing abnormal fibrillin. (wikipedia.org)
Marfan syndrome arises from a change in a gene that codes for the protein fibrillin, which is a key component of connective tissue. (medicalnewstoday.com)
Other connective tissue diseases seen in mast cell patients include Marfan Syndrome and Loeys-Dietz Syndrome. (mastattack.org)
Marfan syndrome is caused by a defect in the connective tissue protein fibrillin. (born-wild.com)

They may also order tests to look for the presence of antibodies more closely associated with other autoimmune diseases to ensure an accurate diagnosis and/or confirm an overlap syndrome. (healthline.com)
Diagnosis of mixed connective tissue disease is supported by detecting abnormal antibodies in the blood. (orthopedicshealth.com)
The second category includes those where the connective tissue is the target of antibodies directed against it. (born-wild.com)
Connective tissue diseases characterized by inflammation are caused by antibodies called autoantibodies that the body incorrectly makes to attack its own tissues. (born-wild.com)
These may occur due to genetics, environmental factors, or be an autoimmune disease, in which antibodies that usually protect the body against infection, attack themselves. (integrativetelemedicine.com)
True mixed connective tissue disease is diagnosed when patients demonstrate the clinical features (exam findings) of overlap illnesses and have high amounts of the antibodies ANA and anti-RNP in their blood. (understandingmyositis.org)
In cases of systemic autoimmune disease, the antibodies target not only one organ but multiple areas of the dog's body. (dogzhealth.com)
Specifically, the red blood cells are destroyed prematurely by auto-antibodies that attack the antigens on the surface of the cells. (dogzhealth.com)
As such, a variety of symptoms can arise depending on which organ(s) the antibodies attack. (dogzhealth.com)
How Addison's disease works is that it tells antibodies to attach to the adrenal cortex and destroy the cells that make cortisol and aldosterone. (northwestpharmacy.com)

Fibromyalgia isn't considered an autoimmune or an inflammation-based disease. (bondclinic.com)

Cold and numb fingers or toes (Raynaud's disease). (orthopedicshealth.com)

Its "burning, aching pain" stems from interference with nerves and bands of muscles and connective tissue, Eldeeb said. (bondclinic.com)
If there are fewer points, it's likely to be myofascial pain, a chronic, painful condition affecting connective tissue that cover the muscles (fascia). (bondclinic.com)
Small, fluid-filled sacs, called bursae, cushion parts of the joint where friction is particularly high and could causing rubbing on bones, muscles, or other soft tissue. (impactphysiotherapy.ca)
Spearman correlation analysis was used to analyse the correlation of fasciculation grade with disease duration, ALSFRS score, total MRC score of all limb muscles, MRC score of the muscle, age of onset, and region of onset. (bvsalud.org)

Osteogenesis imperfecta (brittle bone disease) - caused by poor quality collagen, or insufficient amounts of normal collagen (primarily type I), necessary for healthy, strong bones and certain other connective tissues. (wikipedia.org)
Experts still aren't sure why cartilage, the shock-absorbing tissue that normally coats the ends of bones, sometimes breaks down. (besthealthmag.ca)
Osteogenesis imperfecta (brittle bone disease) - caused by insufficient production of good quality collagen to produce healthy, strong bones. (wikidoc.org)

However, each of these diseases can evolve slowly or rapidly from very subtle abnormalities before demonstrating the classic features that help in the diagnosis. (wikipedia.org)
People often have trouble getting the correct diagnosis because psoriasis-and especially psoriatic arthritis-mimics many other diseases. (health.am)
The diagnosis of psoriatic arthritis or psoriasis may be troubling and shocking, but it can help you to take control of your disease. (health.am)
In these cases, doctors often refer to the diagnosis as mixed connective tissue disease . (born-wild.com)
This study aimed to identify potential biomarkers in disease monitoring and differential diagnosis of adult SMA patients with sporadic ALS patients. (bvsalud.org)
Possible diagnosis requires 3 major criteria without serologic evidence of disease or, if anti-U1 RNP is greater than 1:100, 2 major criteria or 1 major and 3 minor criteria. (medscape.com)

Polymyositis is an autoimmune connective tissue disease that leads to muscle inflammation. (integrativetelemedicine.com)

Diseases in which inflammation or weakness of collagen tends to occur are also referred to as collagen diseases. (wikipedia.org)
Inherited connective tissue diseases occur as a result of genetics. (medicalnewstoday.com)
I often joke that it would be easier to list what conditions are not commonly associated with mast cell disease because so many conditions occur alongside it. (mastattack.org)
MCAS can occur secondarily to lots of GI diseases. (mastattack.org)
These connective tissue diseases occur for unknown reasons. (orthopedicshealth.com)
It is now known that overlap syndromes can occur that involve any combination of the connective tissue diseases. (orthopedicshealth.com)
Pruritus or autoimmune itching can have different amounts of severity and may occur despite not having an autoimmune connective tissue disorder. (integrativetelemedicine.com)

This disorder attacks and destroys healthy tissue in the body. (healthstatus.com)
Mixed connective tissue disease (MCTD) is a rare autoimmune disorder. (healthline.com)
What is an autoimmune disorder of connective tissue? (msdmanuals.com)
How can doctors tell I have an autoimmune disorder of connective tissue? (msdmanuals.com)
How do doctors treat an autoimmune disorder of connective tissue? (msdmanuals.com)

Primary Raynaud phenomenon rarely affects the nutritive flow, whereas secondary Raynaud phenomenon can cause digital artery vasospasm severe enough to block the nutritive flow, leading to tissue hypoxia and ischemia. (medscape.com)
Relapsing polychondritis is an autoimmune disease that affects the cartilage in the body. (tripod.com)
Coronary artery disease, also called CAD, is a condition that affects your heart. (mayoclinic.org)
Pepper spot disease is the other condition that affects the quality of crab meat. (vims.edu)
Periodontal disease is a chronic bacterial infection that affects the gingiva and bone that supports the teeth. (bvsalud.org)

In patients with connective tissue disease, it is common for collagen and elastin to become injured by inflammation (ICT). (wikipedia.org)

Pathological Considerations Also called Little's Disease or Congenital Spastic Paralysis, this condition is usually the result of developmental defects in the brain or central nervous system or from trauma at birth. (ecopolitan.com)
Congenital heart valve disease is malformations of the heart valves, such as missing one of its leaflets. (cdc.gov)

It consists of a variety of proteins, such as collagen and elastin, which give the tissue its strength and flexibility. (medicalnewstoday.com)
Genes tell the body how to make proteins, including the ones that make up connective tissue. (medicalnewstoday.com)
If a person inherits a gene that tells their body to make these proteins in an atypical way, the person may have a connective tissue disease from birth. (medicalnewstoday.com)
Many environmental estrogens can attach to these same proteins, fooling the body or tissues by giving them an inappropriate 'estrogen' signal. (ehso.com)
There are many different collagen proteins that vary in amount in each tissue of the body. (orthopedicshealth.com)
Connective tissues comprise proteins like collagen and elastin and also contain some white blood cells or mast cells. (integrativetelemedicine.com)
Because undifferentiated connective tissue disease is so common, people can often get it by eating foods (including some grains) with gluten and other proteins. (no-carb-diet.com)
This review summarizes some immunological factors involved in the development and control of this oral disease, such as: the participation of inflammatory cells in local inflammation, the synthesis of chemotaxis proteins with activation of the complement system and a range of antimicrobial peptides, such as defensins, cathelicidin and saposins. (bvsalud.org)

These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules: collagen and elastin. (wikipedia.org)
Connective tissues are the framework of the cells of the body. (orthopedicshealth.com)
These tissues form a framework or matrix for the body. (orthopedicshealth.com)
Connective tissue is the fibrous tissue that makes up the framework of your body. (mctdfoundation.org)

Heritable connective tissue diseases. (mastattack.org)
Although MCTD is not listed as an heritable disease of connective tissue, there is an association of the histocompatibility complex called HLA (DR4 and DR2 for MCTD) to link family members to similar autoimmune diseases. (mctdfoundation.org)

Centers for Disease Control and Prevention. (cdc.gov)
Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, GA, 2009: 49pp. (cdc.gov)
The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. (cdc.gov)

Collagen vascular diseases can be (but are not necessarily) associated with collagen and blood vessel abnormalities that are autoimmune in nature. (wikipedia.org)
The classic collagen vascular diseases have a "classic" presentation with typical findings that doctors can recognize during an examination. (wikipedia.org)

The definition of infection is, 'Invasion of the body by living pathogenic microorganisms which reproduce and multiply, causing disease by local cellular injury, secretion of a toxin, or antigen-antibody reaction in the host. (dentistryiq.com)
This is the bacterial infection aspect of periodontal disease. (dentistryiq.com)
Subgingival bacterial biofilm accumulates and matures in the sulcus, releasing toxins that penetrate the junctional epithelium and pass into the underlying connective tissues - infection. (dentistryiq.com)
People with heart disease are at higher risk for severe complications from any infection, so it's in their best interest to get the flu vaccine. (everydayhealth.com)
It can be hereditary or caused by damage to the heart after a heart attack, years of untreated hypertension , heart valve abnormalities, or infection. (everydayhealth.com)
That something is probably an infection that the body is fighting and attacking itself, or it is something like thyroid problems. (no-carb-diet.com)

First-line agents such as nonsteroidal anti-inflammatory agents can be used initially, but some patients may require more advanced treatment with the antimalarial drug hydroxychloroquine ( Plaquenil ) or other disease-modifying agents and biologics. (healthline.com)
Connective tissue or systemic inflammatory diseases. (upmc.com)
Histopathologic studies have found evidence of inflammatory infiltrate in lymphedematous tissue ( 14 , 15 ). (cdc.gov)
Upon proteolytic activation, an enzymatic cascade is propagated, resulting in recruitment of inflammatory cells, amplification of their phagocytic capacity, and formation of membrane attack complexes that promote lysis of microbes. (medscape.com)
This chronic inflammatory disease results from the response to bacteria in dental biofilm and may remain confined to the gingival tissues with minimal tissue alterations or this disease may progress to extreme periodontal destruction with the loss of attachment and alveolar bone. (bvsalud.org)
genetic and environmental factors seem to increase the susceptibility of some individuals in developing this severe inflammatory disease (1) ( Fig. 1 ). (bvsalud.org)

A Danish study of health data on more than 345,000 children shows an unexpected association between height, body mass index (BMI) and the risk of developing the autoimmune disease systemic lupus erythematosus in adulthood. (sciencenews.dk)

A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. (wikipedia.org)
When something goes wrong with this vital tissue, it can have a ripple effect throughout the body. (medicalnewstoday.com)
The connective tissues are the structural portions of our body that essentially hold the cells of the body together. (orthopedicshealth.com)
Connective tissue holds the cells of our body together. (born-wild.com)
Connective tissues are a group of tissues that hold the body together and maintain its shape by providing cohesion and supporting it. (integrativetelemedicine.com)
They hold all the cells of our body together and provide tissues the elasticity required to return to their original position. (integrativetelemedicine.com)
Since connective tissues are in all parts of the body, the disease can have many complications, however, the most prevalent, and of utmost concern, is the potential for lung disease. (understandingmyositis.org)
The more fat in the body, the higher the degree of inflammation, and similar to other autoimmune diseases, this may contribute to developing lupus. (sciencenews.dk)
A connective tissue disease is any disease that has the connective tissues of the body as a primary target of pathology. (wikidoc.org)
Specifically, it mistakenly sees some part of the body as foreign and starts to attack it. (dogzhealth.com)
Autoimmune diseases can affect a single organ, or it can be systemic (whole body). (dogzhealth.com)
The article says that the body is designed with a few different types of connective tissue, but that all of them "undifferentiated" or "unconnected. (no-carb-diet.com)
The disease may be an autoimmune disease, in which the body defends itself against something, or it may be more of a genetic disease, in which the body has a genetic defect that leads to an autoimmune disease. (no-carb-diet.com)

In a second extended model of COVID-19 patients included in the study group, 2,374 SARD patients were matched with 2,374 non-SARD patients with two additional variables: comorbidities (hypertension, heart disease, chronic kidney disease, asthma, chronic obstructive pulmonary disease, type 2 diabetes) and prior health care utilization. (sjogrenscanada.org)

To reach the sulcus quickly and to avoid moving cell to cell, the PMNs use cytokines (chemical machetes) to cut their way through the healthy tissue. (dentistryiq.com)
Keeping white blood cells lower can prevent an attack on healthy tissue. (northwestpharmacy.com)

The potential link between periodontal disease and systemic conditions reinforces the importance of recognizing, treating, and preventing periodontal disease. (dentistryiq.com)
Technically, inflammation more accurately describes the periodontal disease process. (dentistryiq.com)
Therefore, there is general support for this concept of periodontal disease. (bvsalud.org)

Because vasospasm is associated with concurrent ischemia, attacks are typically painful and asymmetric involvement of digits or hands is common. (logicalimages.com)
Patients with MCTD typically experience features of each of these three diseases. (understandingmyositis.org)
Collagen vascular disease is a somewhat antiquated term used to describe diseases of the connective tissues that typically include diseases which can be (but are not necessarily) associated with blood vessel abnormalities. (wikidoc.org)

Anatomy7

Diseases36

Chemicals and Drugs23

Analytical, Diagnostic and Therapeutic Techniques and Equipment9

Phenomena and Processes1

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science1

Health Care2

Rheumatoid13

Blood vessels9

Tendons3

Organs14

Disorders10

Known as connective tissue d2

Ligaments3

Different types of autoimmune3

Symptoms of connective tissue d2

Immune34

Inflammation of the connective2

Rheumatic18

Course of connective1

Affect connective1

Joints9

Body's connective1

Medically1

Ehlers-Danlos3

Genetic connective1

Occurs5

Scleroderma6

Marfan4

Antibodies10

Considered an autoimmune1

Raynaud's1

Muscles4

Bones3

Diagnosis6

Polymyositis1

Occur7

Disorder5

Affects5

Injured by inflammation1

Congenital2

Proteins8

Framework4

Heritable2

Centers for Diseas3

Collagen vascular2

Infection6

Inflammatory6

Lupus erythematosus1

Body13

Chronic obstruc1

Healthy tissue2

Periodontal disease3

Typically3