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AtropineMuscarinic AntagonistsParasympatholyticsGene DosageDosage Compensation, GeneticAtropine DerivativesDosage FormsReceptors, MuscarinicHexamethonium CompoundsAcetylcholinePralidoxime CompoundsPhysostigmineParasympathomimeticsParasympathetic Nervous SystemVagus NerveCarbacholMydriaticsMuscle, SmoothPirenzepineDose-Response Relationship, DrugNeostigmineAutonomic AgentsElectric StimulationOrganophosphate PoisoningMethacholine CompoundsGuinea PigsPropranololMuscle ContractionGuanethidineGlycopyrrolateVagotomyHeart RateMuscarinic AgonistsCholinesterase InhibitorsPhentolamineCholinesterase ReactivatorsBethanecholGastrointestinal MotilityIleumAntidotesTetrodotoxinCholinergic FibersAutonomic Nervous SystemDogsBethanechol CompoundsBradycardiaOxotremorineSalivationReceptors, CholinergicPreanesthetic MedicationQuinuclidinyl BenzilateCholinergic AgonistsScopolamine HydrobromideCholinergic AgentsCholinergic AntagonistsGanglionic BlockersMuscarineTime FactorsDichlorvosTropanesHistamineStomachSympatholyticsCatsBlood PressureDepression, ChemicalPentolinium TartrateMuscle RelaxationSomanBretylium CompoundsNorepinephrineMecamylamineTracheaOphthalmic SolutionsUrinary BladderAdministration, OralX ChromosomeGastric JuiceDrug InteractionsReceptor, Muscarinic M3Vasoactive Intestinal PeptideMethysergideReflexSympathomimeticsSecretory RateInjections, IntravenousMetiamideDrug Dosage CalculationsDimethylphenylpiperazinium IodideSubstance PPhenoxybenzamineReceptor, Muscarinic M2PilocarpineGastric FundusN-MethylscopolamineTachykininsMetipranololRabbitsBenzilatesAdjuvants, Anesthesia
SulfateIndicationsInjectionDiphenoxylateIsopto AtropineMechanism of ActIpratropiumMedicationTitrateAutoinjectorOphthalmicDosesParenteralMuscarinic effectsAdverseMaximum DosageGenericLiquidReceptorsDosingPatientsDropsAdministration0.25ClinicalCautionAllergyEffectsVeterinarianEssentialTreatmentDoctorSymptomsDurationLiverChildren
Sulfate14
  • These highlights do not include all the information needed to use ATROPINE SULFATE INJECTION safely and effectively. (nih.gov)
  • See full prescribing information for ATROPINE SULFATE INJECTION. (nih.gov)
  • Atropine Sulfate Injection, USP, is indicated for temporary blockade of severe or life threatening muscarinic effects, e.g., as an antisialagogue, an antivagal agent, an antidote for organophosphorus or muscarinic mushroom poisoning, and to treat bradyasystolic cardiac arrest. (nih.gov)
  • Limit the total dose of atropine sulfate to 0.03 to 0.04 mg/kg [see Warnings and Precautions (5.1) ]. (nih.gov)
  • 0.4 mg/mL: containing 0.4 mg of atropine sulfate monohydrate equivalent to 0.332 mg of atropine. (nih.gov)
  • Atropine sulfate eye drops is used to dilate the pupil before eye exams. (drugs.com)
  • Use of atropine sulfate eye drops in children younger than 3 months old is not recommended. (drugs.com)
  • Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of atropine sulfate eye drops in the elderly. (drugs.com)
  • Atropine Sulfate dilates your pet's pupils prior to eye examinations. (vetdepot.com)
  • Atropine Sulfate is an anti-muscarinic and works by blocking receptors in the eye muscles that are involved in controlling the shape of the lens and the size of the pupils. (vetdepot.com)
  • Atropine Sulfate 15 mg, Sodium Chloride 9 mg, Benzyl Alcohol (preservative) 1%, Water for Injection q.s. (vetdepot.com)
  • Atropine Sulfate is intended for use on animals only. (vetdepot.com)
  • It is generally available as a sulfate salt and oral atropine is only available in combination products. (sharkvet.com)
  • Atropine or atropine sulfate carries FDA indications for anti-sialagogue/anti-vagal effect, organophosphate/muscarinic poisoning, and bradycardia. (statpearls.com)
Indications3
Injection6
  • Special studies on neurotoxicity Chickens were administered fensulfothion orally or by intraperitoneal injection at dosage levels ranging from 0.005 to 0.05 gm/kg (the birds were administered atropine and 2-PAM prior to fensulfothion). (inchem.org)
  • Atropine Injection veterinary 10 mg/ml is a muscarinic antagonist that is used to treat poisoning by muscarinic agents, including organophosphates and other drugs. (sharkvet.com)
  • Atropine Injection veterinary 10 mg/ml is a competitive, reversible antagonist of muscarinic receptors that blocks the effects of acetylcholine and other choline esters. (sharkvet.com)
  • Atropine Injection veterinary 10 mg/ml is relatively inexpensive and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal, and ophthalmic methods. (sharkvet.com)
  • Atropine Injection veterinary 10 mg/ml is often given with several anesthetic agents to prevent a slow heart rate. (sharkvet.com)
  • Atropine Injection veterinary 10 mg/ml should not be used in animals known to be hypersensitive or sensitive to the drug. (sharkvet.com)
Diphenoxylate3
  • Each tablet contains Diphenoxylate HCI 2.5mg and Atropine Sulphate 0.025mg. (onlinepharmacy.co.nz)
  • Atropine/diphenoxylate is an antimotility agent that can be useful in the treatment of diarrhea as second-line therapy by allowing the central-acting opioid effect of diphenoxylate and capitalization on its anticholinergic side effect of constipation to slow motility. (statpearls.com)
  • Subtherapeutic amounts of atropine are included in the dosage form to discourage diphenoxylate abuse. (statpearls.com)
Isopto Atropine15
Mechanism of Act1
Ipratropium1
  • Ipratropium bromide is an anticholinergic bronchodilator chemically described as 8-azoniabicyclo[3.2.1] octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl8-(1-methylethyl)-, bromide monohydrate, (3-endo, 8-syn)-: a synthetic quaternary ammonium compound chemically related to atropine . (rxlist.com)
Medication1
  • Atropine is a prescription pet medication that is used as a mydriatic to dilate the pupils and as a cycloplegic to help control pain associated with corneal or uveal disease. (vetdepot.com)
Titrate1
  • Clinical findings against which to titrate atropine dosage. (cdc.gov)
Autoinjector1
  • These atropine autoinjectors are packaged with a 2-PAM autoinjector, called Mark I kits. (cdc.gov)
Ophthalmic1
Doses5
  • Type of cholinesterase inhibitor toxicity that may require extremely high doses of atropine. (cdc.gov)
  • 2002) Thus, even when given sufficient doses of atropine, patients may need artificial ventilation, sometimes for weeks. (cdc.gov)
  • Some cases of mild to moderate poisonings may improve with these doses of atropine. (cdc.gov)
  • One author suggest avoiding large doses of pre-mixed atropine containing alcohol preservatives in children out of concern that alcohol toxicity could complicate the situation. (cdc.gov)
  • If there is no improvement in the clinical state after repeat doses of atropine, additional treatments with atropine are unlikely to be effective. (statpearls.com)
Parenteral2
  • If miosis (pupillary constriction) is due to direct conjunctival vapor exposure, it is relatively unresponsive to parenteral atropine. (cdc.gov)
  • Parenteral atropine is not generally recommended for those whose sole manifestation of toxicity is miosis (pupillary constriction). (cdc.gov)
Muscarinic effects2
  • Atropine is a muscarinic antagonist indicated for temporary blockade of severe or life threatening muscarinic effects. (nih.gov)
  • Atropine is only useful to counter muscarinic effects (pralidoxime and benzodiazepines act on the others). (statpearls.com)
Adverse3
  • Describe the potential adverse effects of atropine. (statpearls.com)
  • Review interprofessional team strategies for improving care coordination and communication to enhance patient outcomes and minimize adverse events with atropine. (statpearls.com)
  • Mustard gas produces significant adverse health effects over a wide range of dosages. (who.int)
Maximum Dosage1
Generic2
Liquid1
  • On bare skin, 4 g-5 g of liquid mustard gas may constitute a lethal percutaneous dosage, while droplets of a few milligrams may cause incapacitation and significant skin damage and burns. (who.int)
Receptors3
  • Atropine is not thought to have significant effect on nicotinic receptors, and thus does not counteract fasciculations, weakness, or flaccid paralysis. (cdc.gov)
  • Atropine acts as a competitive, reversible antagonist of muscarinic receptors: an anticholinergic drug. (statpearls.com)
  • Atropine is an antimuscarinic that works through competitive inhibition of postganglionic acetylcholine receptors and direct vagolytic action, which leads to parasympathetic inhibition of the acetylcholine receptors in smooth muscle. (statpearls.com)
Dosing1
  • However, transient improvements with repeat dosing are an indication to continue treatment with atropine (which may exceed standard cumulative dosing maximums). (statpearls.com)
Patients1
  • When the recurrent use of atropine is essential in patients with coronary artery disease, the total dose should be restricted to 2 to 3 mg (maximum 0.03 to 0.04 mg/kg) to avoid the detrimental effects of atropine-induced tachycardia on myocardial oxygen demand. (nih.gov)
Drops2
  • The recommended dosage for treatment of inflammatory condition of the eye is 1-2 drops two or three times per day. (northdrugstore.com)
  • Once irrigated, eye lesions should be treated by applying petroleum jelly on follicular margins to prevent sticking, and the use of cyclopegic eye drops, such as atropine or homatropine to prevent adhesion of the iris to the cornea. (who.int)
Administration2
  • Both the loss of balance and dry mouth that you describe are potential side effects of atropine administration. (vetinfo.com)
  • Preferred routes of administration of atropine. (cdc.gov)
0.251
  • The recommended dosage for dogs is 0.25 - 0.5 mg/lbs (0.5 to 1 mg/kg) orally twice a day or 1.5 - 2.5 mg/lbs (3 - 5 mg/kg) orally every 8 to 12 hours. (petcarerx.com)
Clinical1
  • The duration of the dosage is based on the clinical condition of the pet and it is advised to complete the prescription unless otherwise directed by the veterinarian or pharmacist. (petcarerx.com)
Caution1
  • Atropine should be used with caution in animals that have rapid heart rates or if kidney, heart, or liver function is impaired. (sharkvet.com)
Allergy1
Effects3
  • Mechanism by which atropine counters the effects of the cholinergic toxidrome. (cdc.gov)
  • Atropine works by competitively occupying muscarinic receptor sites, thus reducing the effects of excessive acetylcholine on these sites brought about by cholinesterase inhibition. (cdc.gov)
  • While atropine can be used independently for anti-salivation effects, it is not formally recommended for routine use in controlled airways, though it can be used off-label for minimizing secretions in the intubated patient. (statpearls.com)
Veterinarian1
Essential1
  • Atropine is included in the World Health Organization List of Essential Medicines. (sharkvet.com)
Treatment1
Doctor2
  • Your doctor will prescribe you the correct dosage. (northdrugstore.com)
  • Your doctor will determine your dosage of sermorelin, depending on your body's needs. (hghtherapydoc.com)
Symptoms1
Duration1
  • The benefit of this is that it often shortens the duration or lessens the required dosage of HGH therapy. (hghtherapydoc.com)
Liver1
  • Atropine is removed from the body by the liver and kidneys. (vetinfo.com)
Children2
  • Store Atropine Ointment at controlled room temperature, between 59 and 86 degrees F. Keep away from children and animals. (vetdepot.com)
  • The dosage of loperamide for children (msdmanuals.com)