• Diphenoxylate is rapidly and extensively metabolized in man by ester hydrolysis to diphenoxylic acid (difenoxine), which is biologically active and the major metabolite in the blood. (nih.gov)
  • Atropine and diphenoxylate is a combination medicine used to treat diarrhea in adults and children who are at least 13 years old. (adventisthealthcare.com)
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