AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Atmospheric PressureChromatography, High Pressure LiquidPressureHydrostatic PressurePlasma GasesMass SpectrometrySpectrometry, Mass, Electrospray IonizationBlood PressureAir IonizationChromatography, LiquidAir PressureWeatherChromatography, Thin LayerHyperbaric OxygenationChromatography, GelChemical ProcessesGas Chromatography-Mass SpectrometryChromatography, AffinityKineticsChromatography, Ion ExchangeAmino Acid SequenceChromatographyAirTandem Mass SpectrometryChromatography, GasSubmarine MedicineMolecular WeightPeptide FragmentsHigh Pressure Neurological SyndromeMolecular Sequence DataIndicators and ReagentsTemperatureReproducibility of ResultsTime FactorsHexachlorobenzeneGasesIonsArgonElectrophoresis, Polyacrylamide GelMeteorological ConceptsHeliumBlood Pressure DeterminationLavandulaTrypsinHumidityCattleComplex MixturesAmino AcidsArachidonate LipoxygenasesStereoisomerismMolecular StructureOxygenCalibrationSpectrophotometry, UltravioletLipoxygenaseMagnetic Resonance SpectroscopySensitivity and SpecificityHypertensionSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationTransducers, PressureReference StandardsRadioimmunoassayIntracranial PressureIntraocular PressureRats, Inbred StrainsHydroxyeicosatetraenoic AcidsBlood Pressure Monitoring, AmbulatoryWaterSterilizationCyanogen BromideSeasonsPhotochemistryModels, ChemicalEquipment DesignSubstrate SpecificityBiotransformationSpectrometry, Mass, Fast Atom BombardmentHydrogen-Ion ConcentrationSolventsVenous PressureArachidonic AcidsPeptidesAortic RuptureRabbitsSRS-ANeurotensinDogs12-Hydroxy-5,8,10,14-eicosatetraenoic AcidSwineArterial PressureVentricular PressurePeptide MappingLasersCarbohydrate SequenceHeart RateIsomerismOligosaccharidesIonic LiquidsAffinity LabelsLiver
Tandem Mass SpectroHPLCTime-of-flight maIonisationDetectionAPCIMassTriple quadrupoleAnalytical techniques1998DeterminationUrineIonsRetentionAnalytesLipidsExtractionFingerprintSeparationMethodReversed-phaseQuadrupoleSensitivityCompoundsBergerJournalEnvironmentalVolatileChemistryThroughputUnexpectedlyTechniquesColumnResearchSampleMolecularGradientAffinityAcidOccurRegressionFormDiagnosisTemperatures
Tandem Mass Spectro6
  • The test principle utilizes high performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry (HPLC-APPI-MS/MS) for the quantitative detection of genistein, daidzein, equol, O-desmethylangolensin, enterodiol, and enterolactone. (cdc.gov)
  • 2008) was utilized and in 2005-2006 high performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry (LC-ESI-MS/MS) was utilized. (cdc.gov)
  • Method for determination of acephate, methamidophos, omethoate, dimethoate, ethylenethiourea and propylenethiourea in human urine using high-performance liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry. (cdc.gov)
  • mono-n-butyl phthalate is chromatographically resolved by reverse-phase HPLC, detected by negative ion atmospheric pressure chemical ionization (APCI) tandem mass spectrometry, and quantified by isotope dilution. (cdc.gov)
  • In this study, a sensitive and reliable method based on an ultra-performance liquid chromatography (UPLC) couple with two ionisation modes, including electrospray ionisation (ESI) and atmospheric pressure chemical ionisation (APCI) tandem mass spectrometry (MS), namely, UPLC-ESI/APCI-MS/MS was developed and validated to simultaneously determine 8 triterpenoids (ESI mode) and 2 sesquiterpenoids (APCI mode) in RA. (hindawi.com)
  • Recently, we introduced a heated nebulizer microchip and showed its potential to interface liquid microseparation techniques and GC with API-MS. This study demonstrates the feasibility of GC-microchip atmospheric pressure photoionization-tandem mass spectrometry (GC-μAPPI-MS/MS) in the analysis of underivatized anabolic steroids in urine. (aalto.fi)
HPLC16
  • Conifer seed oils from European Larch (Larix decidua), Norway Spruce (Picea abies) and European Silver Fir (Abies alba) have been analyzed by non-aqueous reversed-phase high-performance liquid chromatography (NARP-HPLC) with atmospheric pressure chemical ionisation (APCI)-MS detection. (unboundmedicine.com)
  • The most common form of liquid chromatography in use today is high-performance liquid chromatography (HPLC), which pumps the sample mixture through the column at high pressure. (europeanpharmaceuticalreview.com)
  • HPLC is the form of liquid chromatography that is generally used in the pharmaceutical industry, as it can provide the precise results that are required. (europeanpharmaceuticalreview.com)
  • Although expected at first to be used as a complimentary method to gas chromatography, the pharmaceutical industry now almost exclusively uses HPLC as a chromatographic technique. (europeanpharmaceuticalreview.com)
  • 3 HPLC is especially suitable for compounds that are not easily volatilised, thermally unstable and have high molecular weights. (europeanpharmaceuticalreview.com)
  • To characterize the triglycerides in modified soybean oil samples, a technique called high-performance liquid chromatography (HPLC) was used to separate the different triglycerides. (usda.gov)
  • Canola oil triacylglycerols from genetically modified canola lines were conclusively identified by reversed-phase HPLC coupled with atmospheric pressure chemical ionization mass spectrometric (APCI-MS) detection. (usda.gov)
  • Di-n-butyl phthalate may be determined by high resolution gas chromatography with an electron capture detector (HRGC/ECD) (EPA 1984b), gas chromatography/mass spectrometry (GC/MS) (EPA 1994a), gas chromatography with a flame ionization detector (GC/FID) (NIOSH 1994), gas chromatography/Fourier transform infrared spectrometry (GC/FTIR) (EPA 1994b), high performance liquid chromatography/mass spectrometry (HPLC/MS) (Coldham et al. (cdc.gov)
  • 1998), or high performance liquid chromatography/ion-trap mass spectrometry (HPLC/Ion Trap-MS) (Coldham et al. (cdc.gov)
  • Extracts of plant material or of dyed silk or wool were analyzed by HPLC with photodiode array and mass spectrometric detection using an Agilent 1100 high performance liquid chromatography system consisting of an automatic injector, a gradient pump, a Hewlett-Packard series 1100 photodiode array detector, and an Agilent series 1100 VL on-line atmospheric pressure ionization electrospray ionization mass spectrometer. (mfa.org)
  • A rapid and sensitive high-performance liquid chromatographic mass spectrometric (HPLC-MS) method is described for the determination and quantification of 12 dietary flavonoid glycosides and aglycons in human urine samples. (ku.dk)
  • Agilent 1260 Binary High-performance liquid chromatograph (HPLC) coupled with Quadrupole Time of Flight Mass Spectrometer (Agilent 6545 QTOF MS). (dri.edu)
  • Shimadzu Prominence HPLC coupled with a triple-quadrupole mass spectrometer (AB Sciex API 3200 LC-MS/MS), equipped with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) sources. (dri.edu)
  • Waters high performance liquid chromatograph (HPLC) equipped with Waters 2695 Alliance separation module, Waters 996 Photodiode Array Detector and Empower chromatography software. (dri.edu)
  • Most practical high-performance liquid chromatography (HPLC) is done under conditions where flow through connecting tubing in the system is laminar. (chromatographyonline.com)
  • The Agilent 6410 Triple Quadrupole LCMS combines the separation power of High Performance Liquid Chromatography (HPLC) with the detection power of a triple quad instrument and provides the highest levels of sensitivity and selectivity for targeted analysis of small molecules in complex samples such as tissue homogenates, blood, or lysates from cell cultures. (auckland.ac.nz)
Time-of-flight ma1
  • The aim of this study was to apply two analytical techniques for the untargeted analysis of selected e-liquids using Headspace - Solid Phase Microextraction - Gas Chromatography - Mass Spectrometry (HS-SPME-GCMS) and Liquid Chromatography coupled with Time-of-flight Mass Spectrometry (LC-ToF-MS). A 1 cm Stableflex DVB/CAR/PDMS fiber was used in the HS-SPME-GCMS analysis, providing the pre-concentration of volatile and semi-volatiles compounds. (coresta.org)
Ionisation4
  • First, gas chromatography ( GC ) coupled to mass spectrometry ( MS ) in electron ionisation mode was used to identify migrants through spectral library matching. (sciensano.be)
  • When no acceptable match was obtained, a second analysis by GC -(electron ionisation) high resolution mass spectrometry time of flight ( TOF ) was applied to obtain accurate mass fragmentation spectra and isotopic patterns. (sciensano.be)
  • Finally, a GC hybrid quadrupole-TOF-MS with an atmospheric pressure chemical ionisation source was used to obtain the molecular ion or the protonated molecule. (sciensano.be)
  • And finally the use of atmospheric pressure laser ionisation (APLI) for liquid chromatography/mass spectrometry (LC/MS) is investigated. (manchester.ac.uk)
Detection4
APCI3
  • TGs containing Delta5-UPIFAs have a higher retention in comparison with common TGs found in plant oils with single methylene interrupted Delta6(9)-FAs and also significantly changed relative abundances of fragment ions in APCI mass spectra. (unboundmedicine.com)
  • Waters UPLC coupled with electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) MS/MS, and Evaporative Light Scattering Detector (Waters Acquity UPLC/Quattro micro API/ELSD). (dri.edu)
  • The Multimode Ionization (MMI) source incorporates both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) into a single ion source. (auckland.ac.nz)
Mass16
  • The PSI-MS method described here was comparable to the conventional ones, such as liquid chromatography coupled with mass spectrometry and gas chromatography coupled with mass spectrometry described in the literature. (springer.com)
  • Asati A, Satyanarayana GNV, Panchal S, Thakur RS, Ansari NG, Patel DK (2017) Ionic liquid based vortex assisted liquid-liquid microextraction combined with liquid chromatography mass spectrometry for the determination of bisphenols in thermal papers with the aid of response surface methodology. (springer.com)
  • Gas chromatography-mass spectrometry (GC-MS) was used in the qualitative analysis of RA for the volatile oil, containing sesquiterpenoids [ 25 ]. (hindawi.com)
  • METHODS:The endocannabinoid levels were measured in peripheral and hepatic veins and liver tissue by isotope-dilution liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry. (unifi.it)
  • Mass spectrometers equipped with atmospheric pressure ion sources (API-MS) have been designed to be interfaced with liquid chromatographs (LC) and have rarely been connected to gas chromatographs (GC). (aalto.fi)
  • His primary areas of investigation include Environmental chemistry, Chromatography, Mass spectrometry, Perfluorooctanoic acid and Perfluorooctane. (research.com)
  • His study in Mass spectrometry is interdisciplinary in nature, drawing from both Atmospheric-pressure chemical ionization and Chemical ionization. (research.com)
  • The Quantitative Measurement of Peptidoglycan Components Obtained from Acidic Hydrolysis in Gram-Positive and Gram-Negative Bacteria via Hydrophilic Interaction Liquid Chromatography Coupled with Mass Spectrometr. (tftak.eu)
  • Quantitative Analysis of Oat (Avena sativa L.) and Pea (Pisum sativum L.) Saponins in Plant-Based Food Products by Hydrophilic Interaction Liquid Chromatography Coupled with Mass Spectrometry. (tftak.eu)
  • The Q-Exactive, installed in the IBMCP Chromatography Laboratory, is a mass spectrometer with an Orbitrap analyzer with high resolution and mass accuracy. (upv.es)
  • Waters Acquity I-class ultra-high performance liquid chromatography (UPLC) coupled with electrospray ionization (ESI) triple quadrupole tandem mass spectrometer (MS/MS) (Waters Xebo TQ-S MS). (dri.edu)
  • Identification of substances migrating from plastic baby bottles using a combination of low-resolution and high-resolution mass spectrometric analysers coupled to gas and liquid chromatography. (sciensano.be)
  • The use of secondary ion mass spectrometry (SIMS) for high spatial resolution qualitative mass spectrometry imaging (MSI) offers superior lateral resolution over competing technologies. (manchester.ac.uk)
  • There are however various caveats imposed for bioanalytical applications, extensive fragmentation and poor ion yields for high mass analytes both require redress. (manchester.ac.uk)
  • The identity confirmation of the analyte was carried out using liquid chromatography coupled to mass spectrometry, with atmospheric pressure chemical ionization. (unicamp.br)
  • The 14 analytes, separated within 4.15 min using reversed-phase liquid chromatography, were determined using a triple-quadrupole mass spectrometer with atmospheric-pressure chemical ionization and multiple reaction monitoring in negative and positive ionization modes. (cdc.gov)
Triple quadrupole1
  • The Quattro Micro API is a high performance triple quadrupole spectrometer designed for routine LC/MS/MS operation. (labmakelaar.eu)
Analytical techniques1
  • To guarantee that goods pass certain standards, researchers, manufacturers and developers use various technical equipment and analytical techniques , including liquid chromatography, during the development process. (europeanpharmaceuticalreview.com)
19981
  • Human plasma quantification of fludrocortisone using liquid chromatography coupled with atmospheric pressure from a heart attack the 1998 Nobel Prize in Medicine was awarded diabetes mellitus Fludrocortisone Is Associated With a Higher of how thewhich line all of orthostatic hypotension. (nudenutrition.in)
Determination1
  • To better elucidate characteristic compounds present in e-liquids, and monitor potential changes to a product that occur during storage or between lot preparations, the determination of untargeted analytes is a valuable tool. (coresta.org)
Urine2
  • Higher analytes concentrations in hydrolyzed samples showed the presence of conjugated compounds in urine. (erowid.org)
  • A subset of 10 urine samples from a human dietary intervention study with high and low flavonoid content was analyzed, and the results are reported. (ku.dk)
Ions1
  • The APPI microchip provides high ionization efficiency and produces abundant protonated molecules or molecular ions with minimal fragmentation. (aalto.fi)
Retention1
  • Over the last few years, I've focused several "LC Troubleshooting" installments on contemporary trends (such as the relatively recent advances in our understanding of the effects of pressure on retention [2]) in liquid chromatography (LC) that are affecting the way we approach our interpretation of LC results, and approach troubleshooting with modern LC instruments. (chromatographyonline.com)
Analytes2
  • Separated analytes were determined in LC-MS single ion monitoring mode using an atmospheric pressure ionization-electrospray ionization (ESI) interface. (erowid.org)
  • Chromatographic separation of the analytes of interest was achieved by column-switching, using the first column (a Zorbax 300SB C-3 column) for sample cleanup and eluting the heart-cut flavonoid fraction onto the second column (a Zorbax SE C-18 column) for separation and detection by ultraviolet and atmospheric pressure chemical ionization MS using single ion monitoring in negative mode. (ku.dk)
Lipids4
  • It has been proposed that GDGT membrane lipids are an adaptation to the high temperatures present in the environments that are home to extremophile archaea Archaeal GDGTs were first detected in pelagic waters. (wikipedia.org)
  • Originally, it was believed that GDGT membrane lipids were an adaption to life at high temperatures and acidities. (wikipedia.org)
  • It has been proposed that the distinctive cyclohexyl group of crenarchaeol is an adaption to pelagic life, as it produces a "kink" in one of crenarchaeol's hydrocarbon chains that prevents the membrane lipids from packing tightly, as would be favorable under high temperatures but unfavorable under temperate ones. (wikipedia.org)
  • Microalgae can efficiently absorb CO 2 in the atmosphere and turn it into abundant high-value products, including polysaccharides, lipids, proteins, pigments, and biofuels [2-5]. (researchsquare.com)
Extraction3
  • The extraction of 1-DNJ was affected by microwave treatment time, power, solid-liquid ratio and extraction times. (rainbowextract.com)
  • The optimal extraction process was as follows: the extraction rate of 1-DNJ was 0.024%, the microwave treatment time was 1.5min, the power was 406W, the solid-liquid ratio was 1∶40 and the extraction times was 2. (rainbowextract.com)
  • The method includes automated solid-phase extraction using customized positive-pressure functions. (cdc.gov)
Fingerprint1
  • The combination of compounds identified in the different e-liquids by both techniques, present at different levels, create a unique and distinguishable fingerprint of each e-liquid. (coresta.org)
Separation1
Method1
  • In the purification technology, most of the cation exchange resin method, reverse chromatography purification technology is also a little research. (rainbowextract.com)
Reversed-phase1
  • Chromatography was performed on a C(18) reversed-phase column using a linear gradient of 10mM ammonium bicarbonate, pH 7.3 and acetonitrile as a mobile phase. (erowid.org)
Quadrupole1
  • For less volatile unknowns, ultra-high pressure liquid chromatography-quadrupole-TOF-MS was additionally applied. (sciensano.be)
Sensitivity2
  • At present, the diagnosis of CEs is time-consuming, costly and sometimes invasive, also because non-invasive biomarkers with high sensitivity and specificity are not yet available. (frontiersin.org)
  • 1 Metabolites of nicotine (cotinine, trans -3′-hydroxycotinine and their glucuronides, and nicotine glucuronide) and NNK (NNAL (4-[methylnitrosamino]-1-[3-pyridyl]-1-butanol) and its glucuronides) can be measured in SHS-exposed individuals, with high sensitivity in various biological matrices ( table 1 ). (cdc.gov)
Compounds3
  • All marker compounds showed higher fractions under dry conditions when formed during daytime and showed almost no RH effect when formed during night. (copernicus.org)
  • High Blood Pressure A by the amount of assess for presence of with Whites, compounds the to diagnose and treat. (nudenutrition.in)
  • HS-SPME-GCMS analysis indicated the presence of over 120 different flavour compounds including mono- and sesquiterpenes, higher alcohols, esters, pyrazines, lactones and aldehydes. (coresta.org)
Berger1
Journal3
Environmental1
  • Due to their high photosynthetic efficiency, rapid reproduction rate, and short growth cycle, microalgae have been considered as the best candidates to resolve energy crises and environmental pollution [6]. (researchsquare.com)
Volatile1
  • Sheehan, J.J. Effect of β-casein reduction and high heat treatment of micellar casein concentrate on proteolysis, texture and the volatile profile of resultant Emmental cheese during ripening. (tftak.eu)
Chemistry2
  • Leibniz Institute for Tropospheric Research (TROPOS), Atmospheric Chemistry Department (ACD), Permoserstr. (copernicus.org)
  • How does one learn more about the characteristics of the Martian atmospheric chemistry and climate system while seated 56 million plus kilometres away? (lu.se)
Throughput1
  • This high throughput analytical process can prepare and analyze a sample in 9 min and along with the 14-compound analyte panel can be useful for tobacco-exposure studies, in smoking-cessation programs, and for detecting changes in exposure related to tobacco products and their use. (cdc.gov)
Unexpectedly2
  • Surprisingly, unexpectedly high SOA yields were found for m -cresol oxidation with OH radicals (3-9 %), with the highest yield under elevated RH (9 %), which is most likely attributable to a higher fraction of 3-methyl-6-nitro-catechol (MNC). (copernicus.org)
  • Sometimes pressure is unexpectedly low, but stable. (chromatographyonline.com)
Techniques1
Column2
  • a component with a higher affinity for the stationary phase will migrate down the column slower than a component which has more affinity for the mobile phase. (europeanpharmaceuticalreview.com)
  • This single pressure readout quantifies the total pressure drop across the entire flow path, but does not tell us anything about the pressure drops across individual elements of the flow path (for example, filters, different pieces of connecting tubing, and the column). (chromatographyonline.com)
Research1
  • Simulation chambers as tools in atmospheric research (AMT/ACP/GMD. (copernicus.org)
Sample2
Molecular1
  • Spectral identification of the triacylglycerols was based on the diacylglycerol fragments and on the protonated molecular ion [M+H]**+, except trisaturates which gave no [M+H]**+. Triacylglycerols were identified and quantitated in normal, high stearic acid and high lauric acid canola varieties. (usda.gov)
Gradient1
Affinity1
  • marmosets: rodents had higher levels with greater affinity than marmosets. (who.int)
Acid2
  • The oils of the modified canola varieties, compared to typical canola oil, contained increased content of triacylglycerols known to be more oxidatively stable like stearoyloleoyllinoleoyl, distearoyllinoleoyl, stearoyldioleoyl and distearoyloleoyl glycerols in high stearic acid canola oil and dilauroyllinoleoyl, dilauroyloleoyl and lauroyldioleoyl glycerols in high lauric acid canola oil. (usda.gov)
  • Thus, MEHP and perhaps 2-EHA and other di-carboxylic acid concentrations in the body were higher in mice or rats than marmosets when the same dose of DEHP was administered (Ito et al. (who.int)
Occur1
  • Developing a short list of the likely causes of these deviations can help streamline our troubleshooting experience when pressure-related problems occur. (chromatographyonline.com)
Regression1
  • 10%), and linearity (regression coefficient ≥ 0.9995) and, therefore, high potential for the analysis of anabolic steroids. (aalto.fi)
Form1
  • In higher plants and microalgae, there are four major groups of DGATs: (1) the membrane bound form of DGAT1, (2) the membrane bound form of DGAT2 sharing low sequence similarity with DGAT1, (3) the soluble type of DGAT3, which is localized in the cytosol, and (4) the dual function of WS/DGAT, which possesses both wax ester and TAG biosynthesis activities [12-18]. (researchsquare.com)
Diagnosis1
  • a cardiologist at of Droxidopa After Dosing in California, told Healthline and try to understand any safety hazards, reports high blood pressure can the screening, diagnosis, and hour and what will. (nudenutrition.in)
Temperatures1
  • Most GDGTs degrade at between 240 and 300 °C and so are not found in rocks that have undergone heating to temperatures higher than 300 °C. GDGTs undergo degradation when exposed to oxygen but the relative concentrations of sediment GDGTs tends to remain the same even during degradation, meaning that degradation does not interfere with proxies like TEX86 that are based on the ratios of different GDGTs. (wikipedia.org)