Venous thrombosisCoronary Artery AtherosclerosisInflammationArterialEuropean Atherosclerosis SocietyIschemic strokeHaemostasisVascularStent thrombosisLuminal thrombosisClinicalAcuteAtheroscleroticHemostasisCardiovascularPathologyStrokeArteriesPathophysiologyInflammatory diseaseBlood vesselStentsDeep veinsEndothelialCoagulationPatientsRecurrentInhibitGenesGeneticAneurysmSocietyClotCirculating bloodDevelopment
Venous thrombosis5
- Former, the most important site of arterial thrombosis and latter the most important site of venous thrombosis . (wikidoc.org)
- The major pathophysiological mechanisms leading to thrombus formation are similar and overlap in both arterial and venous thrombosis . (wikidoc.org)
- The processes triggering thrombosis and, often, perpetuating the thrombus may be distinct in arterial and venous thrombosis. (wikidoc.org)
- Several risk factors for developing venous thrombosis usually coexist in cancer patients including surgery, hospital admissions and immobilization, the presence of an indwelling central catheter, chemotherapy, use of erythropoiesis-stimulating agents (ESAs) and new molecular-targeted therapies such as antiangiogenic agents. (oncologynurseadvisor.com)
- 1 In 1865, another French physician Armand Trousseau reported an association between gastric cancer and venous thrombosis. (oncologynurseadvisor.com)
Coronary Artery Atherosclerosis2
- Go to Coronary Artery Atherosclerosis and Noncoronary Atherosclerosis for more information on these topics. (medscape.com)
- Coronary artery atherosclerosis is the single largest killer of men and women in the United States. (medscape.com)
Inflammation7
- Processes involved in atherosclerosis include coagulation, inflammation, lipid metabolism, intimal injury, and smooth muscle cell proliferation (see the image below). (medscape.com)
- Platelets are the major source of soluble CD40L in circulation, and the protean effects of CD40L have led some to suggest that platelet CD40L may be a pivotal link between thrombosis, inflammation and atherosclerosis. (biu.ac.il)
- Chronic unresolved vascular inflammation is a critical factor in the development of atherosclerosis. (frontiersin.org)
- Thrombosis and Inflammation-A Dynamic Interplay and the Role of Glycosaminoglycans and Activated Protein C . Frontiers in cardiovascular medicine , 9 , [866751]. (helsinki.fi)
- Kohli S, Shahzad K, Jouppila A , Holthöfer H , Isermann B, Lassila R. Thrombosis and Inflammation-A Dynamic Interplay and the Role of Glycosaminoglycans and Activated Protein C . Frontiers in cardiovascular medicine . (helsinki.fi)
- Inflammation and immunity are key factors for the development and complications of atherosclerosis, and therefore, the whole atherosclerotic process is a target for diagnosis and treatment. (hindawi.com)
- Therefore, with the aim to summarize the current knowledge on the initiation of the atherosclerotic process, in this paper, we review the early markers of atherosclerosis and we address the main therapeutic targets for preventing atheroma formation at its very initial stages focusing on inflammation, oxidative stress, endothelial dysfunction, and the interaction between platelets and endothelium. (hindawi.com)
Arterial3
- Findings in animal models such as TFPI knockout models and gene transfer models are consistent on the role of TFPI in arterial thrombosis as they reveal an active role for TFPI in attenuating arterial thrombus formation. (maastrichtuniversity.nl)
- In contrast, brachial-ankle pulse wave velocity (baPWV) reflected a composite of several arterial segments, some of which were prone to arteriosclerosis alone (brachial and distal arteries) and some to both atherosclerosis and arteriosclerosis (aorta and femoral arteries). (medsci.org)
- arterial infarction can be due to either obstruction from thrombosis or embolism or to occlusion from blood vessel abnormalities such as vasculitis. (vin.com)
European Atherosclerosis Society2
- Atherosclerosis : biology and clinical science / edited by Anders G. Olsson on behalf of the European Atherosclerosis Society. (who.int)
- 2023 Update on European Atherosclerosis Society Consensus Statement on Homozygous Familial Hypercholesterolaemia: new treatments and clinical guidance. (cdc.gov)
Ischemic stroke2
- The current review focuses on TFPI in clinical studies of asymptomatic and symptomatic atherosclerosis, coronary artery disease and ischemic stroke, and discusses potential atheroprotective actions of TFPI. (maastrichtuniversity.nl)
- These physiologic changes influence atherosclerosis , plaque stability and thrombosis - all of which are risk factors of ischemic stroke. (medicalnewstoday.com)
Haemostasis1
- Thrombosis and Haemostasis Wishes You a Happy New Year Ahead! (thieme-connect.com)
Vascular3
- Dr. Balint has experience treating conditions like Atherosclerosis, Venous Insufficiency, Peripheral Vascular Disease (PAD and PVD) among other conditions at varying frequencies. (sharecare.com)
- Endothelial dysfunction is an early marker of atherosclerosis and levels of vascular relaxation are an indicator of endothelial health. (escardio.org)
- Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress and endothelial dysfunction. (hindawi.com)
Stent thrombosis1
- The emergency 5-month follow-up angiogram was performed under the impression of late stent thrombosis. (ewha.ac.kr)
Luminal thrombosis2
- A modified version of the AHA classification was developed by our laboratory to include important pathologic lesions responsible for luminal thrombosis other than plaque rupture, such as plaque erosion and calcified nodule. (medscape.com)
- Sudden luminal thrombosis may arise from three different plaque morphologies: plaque rupture, erosion, and calcified nodule. (medscape.com)
Clinical4
- We are also grateful to Dr. Rodger Bick, President of the International Academy of Clinical and Applied Thrombosis and Hemostasis for his generous support and endorsement of this meeting. (sasat.org)
- Paradoxically, the majority of clinical studies find increased instead of decreased TFPI antigen and activity levels in atherothrombotic disease, particularly in atherosclerosis and coronary artery disease (CAD). (maastrichtuniversity.nl)
- Over the past two decades, its role in the initiation, progression, and clinical sequelae of atherosclerosis has been both increasingly studied and recognised (1). (escardio.org)
- The most important sites of thrombosis formation, based on their frequency and clinical effect are coronary arteries and deep veins of the legs. (wikidoc.org)
Acute3
- Lesion reference to AHA types V and VI was discarded, because it failed to account for the 3 different morphologies (rupture, erosion, and calcified nodule) that give rise to acute coronary thrombosis. (medscape.com)
- [ 1 ] Atherosclerotic plaque rupture with thrombosis is the pathologic mechanism responsible for the majority of acute myocardial infarctions (AMI) and sudden coronary death (SCD). (medscape.com)
- The autopsy showed "severe coronary atherosclerosis," and the pathologist attributed death to "acute coronary thrombosis with ischemic arrhythmia. (cdc.gov)
Atherosclerotic3
- The term atherosclerosis is derived from the Greek "athero," meaning gruel, or wax, corresponding to the necrotic core area at the base of the atherosclerotic plaque, and "sclerosis" for hardening, or induration, referring to the fibrous cap of the plaque's luminal edge. (medscape.com)
- The earliest pathologic descriptions of atherosclerotic lesions focused on morphologies of fatty streaks to fibroatheromas (FAs) and advanced plaques complicated by hemorrhage, calcification, ulceration, and thrombosis. (medscape.com)
- The etiology of atherosclerosis is unknown, but there are multiple factors that contribute to atherosclerotic plaque progression. (medscape.com)
Hemostasis1
- Atherosclerosis is a miss balance between lipid s and the hemostasis system which caused clot in arteries . (wikidoc.org)
Cardiovascular1
- Elevated homocysteine is a known risk factor for cardiovascular disease as well as thrombosis. (wikipedia.org)
Pathology1
- In this brief article, we will discuss the pathology of coronary thrombosis, with emphasis on plaque rupture and its hypothesized precursor lesion, the thin cap fibroatheroma (TCFA). (medscape.com)
Stroke1
- [6] Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis . (wikipedia.org)
Arteries1
- Atherosclerosis and endothelial dysfunction are diffuse disease processes affecting coronary and peripheral arteries, hence, the physiological basis in assessing endothelium-dependent vasomotion in peripheral vessels. (escardio.org)
Pathophysiology1
- This review will focus on the epidemiology and pathophysiology of cancer-associated thrombosis, risk factors, and new predictive biomarkers for VTE as well as discuss novel prevention and management regimens of VTE in cancer according to published guidelines. (oncologynurseadvisor.com)
Inflammatory disease2
Blood vessel1
- Thrombosis is the formation of a thrombus (medical term for a clot ) inside a blood vessel . (wikidoc.org)
Stents1
- those with stents can develop blood clots (thromboses) within the stents, impeding blood flow. (medlineplus.gov)
Deep veins1
- An exceedingly extensive thrombosis in deep veins can extend well into the iliac veins or the inferior vena cava . (wikidoc.org)
Endothelial2
- This disrupts the folate pathway and leads to an increase in homocysteine which damages cells (for example, damage to endothelial cells can result in increased risk of thrombosis). (wikipedia.org)
- Atherosclerosis starts with dysfunctional changes in the endothelium induced by disturbed shear stress which can lead to endothelial and platelet activation, adhesion of monocytes on the activated endothelium, and differentiation into proinflammatory macrophages, which increase the uptake of oxidized LDL (oxLDL) and turn into foam cells, exacerbating the inflammatory signalling. (hindawi.com)
Coagulation2
- It is the propensity to develop thrombosis due to an abnormality in the system of coagulation. (wikidoc.org)
- Usually there is a balance between the coagulation and fibrinolysis systems in order to not having abnormal thrombosis in the body. (wikidoc.org)
Patients3
- Oxidation of low-density lipoprotein (LDL) cholesterol is crucial in the development of atherosclerosis, and low LDL levels reduce the risk of major events in patients with CVD [ 6 ]. (hindawi.com)
- Emerging data have enhanced our understanding of cancer-associated thrombosis, a major cause of morbidity and mortality in patients with cancer. (oncologynurseadvisor.com)
- Factor V Leiden is found in 30-50% of patients with recurrent venous thromboembolism (VTE) and is the most common hereditary cause of thrombosis. (medscape.com)
Recurrent1
- Continuation of therapy beyond that should be based on the risk for recurrent thrombosis versus the risk of major bleeding for each individual patient. (oncologynurseadvisor.com)
Inhibit1
- Conclusion-Nasal administration of an apoB-100 peptide fused to CTB attenuates atherosclerosis and induces regulatory Tr1 cells that inhibit T effector responses to apoB-100. (lu.se)
Genes1
- This grant from the National Heart, Lung and Blood Institute enabled him to further study how genes and diet affect atherosclerosis. (usda.gov)
Genetic1
- Integrative analysis of hepatic transcriptional profiles reveals genetic regulation of atherosclerosis in hyperlipidemic Diversity Outbred-F1 mice. (usda.gov)
Aneurysm3
- These stentlike devices may induce progressive aneurysm thrombosis without additional implants and may initiate complete reverse vessel remodeling. (ajnr.org)
- FDs alone may modify hemodynamics in ways that induce extensive aneurysm thrombosis. (ajnr.org)
- 1 - 5 On the basis of flow-diversion concepts alone, progressive aneurysm thrombosis and reverse remodeling of the aneurysm and the vessel wall are expected, without the use of additional embolic material. (ajnr.org)
Society1
- International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia. (cdc.gov)
Clot1
- Without active clopidogrel to interfere, the P2RY12 receptor continues to promote platelet aggregation and blood clot formation, which can lead to heart attacks, strokes, and thromboses in individuals with a history of these conditions. (medlineplus.gov)
Circulating blood1
- Thrombosis occurs when platelets and inflammatory cells in the circulating blood come into contact with the thrombogenic necrotic core. (medscape.com)
Development2
- In addition, ample experimental evidence exists indicating that TFPI has inhibitory effects on both smooth muscle cell migration and proliferation, both which are recognized as important pathological features in atherosclerosis development. (maastrichtuniversity.nl)
- Oxidation of low-density lipoprotein (LDL) cholesterol is one of the key factors for the development of atherosclerosis. (hindawi.com)