AsymmetricCaulobacterSymmetricallyBacteriumSingle-celledDivisionsGermlineElegansStem cellsCells divide asymmetricallyCorticalYeastOrthogonalStalk cellPolarityMitoticCell divisionPossess the abilityBacteriaNeuroblastAxisDevelopmentalFateEmbryoMother cellPatternsDevelopmentMolecularAbilityGenePrimaryRoleHouseEqualSmallerProvideBalanceModeMeansCaseDomainsNumbersProjects
Asymmetric18
- Caulobacter crescentus is a single-celled, small bacterium that divides asymmetrically producing cells that differ in structure and function - it is an ideal model system for the mechanisms of asymmetric cell division and has been studied thoroughly. (kenyon.edu)
- Retention of labeled DNA strands may be attributed to the ability of stem cells to retain the parental DNA strand during asymmetric cell division ( Cairns, 1975 ) or to quiescence of the stem cell population such that the DNA label is not diluted by frequent cell divisions ( Klein and Simons, 2011 ). (frontiersin.org)
- I look at pseudocleavage, asymmetric division, and whether there are blebs (protrusions of the plasma membrane) at the points of ingression during division. (ursinus.edu)
- Many stem cells undergo asymmetric division to produce a self-renewing stem cell and a differentiating daughter cell. (sdbonline.org)
- This study shows that, similarly to H3 , histone H4 is inherited asymmetrically in Drosophila melanogaster male germline stem cells undergoing asymmetric division. (sdbonline.org)
- Including discussions of the molecular basis of polarization mechanisms, asymmetric division of stem cells during development, the generation of left-right asymmetry of the body axis in mammals, and theoretical approaches to symmetry breaking, the volume is a vital reference for molecular, cell, and developmental biologists, as well as physical scientists interested in how and why symmetry breaking occurs in living systems. (cshlpress.com)
- In Drosophila and mammals, Lgl contributes to the maintenance of cell polarity and plays a role in asymmetric cell division. (biologists.com)
- Asymmetric and self-replacing divisions from the tetrahedral initial generate leaf initials that divide asymmetrically to selfreplace and to produce daughter cells with restricted fate. (ox.ac.uk)
- Her postdoctoral studies on neural stem cells and asymmetric cell division in the Lab of Dr. Yuh Nung Jan at the Howard Hughes Medical Institute and University of San Francisco, California implied for the first time a minus-end directed myosin in the process of cell fate determination. (stanford.edu)
- Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding. (ous-research.no)
- Here, we report that Caenorhabditis elegans CED-3 caspase regulates asymmetric cell division. (ucl.ac.uk)
- Based on these findings, we propose that CED-3 caspase plays a critical role in the asymmetric division by size and fate of neuroblasts, and that this contributes to the reproducibility and robustness with which the smaller daughter cell is produced and adopts the apoptotic fate. (ucl.ac.uk)
- We speculate that the new nonapoptotic function of C. elegans CED-3 caspase in asymmetric neuroblast division is relevant to the function(s) of mammalian caspases in stem cells. (ucl.ac.uk)
- In contrast to current views, we find no evidence for asymmetric division of these primary progenitors. (idival.org)
- Each cell has a label, representing the cell event it will perform, such as division (symmetric or asymmetric, horizontal or vertical), growth, and death. (biomedcentral.com)
- The polarized partitioning of proteins in cells underlies asymmetric cell division, which is an important driver of development and cellular diversity. (figshare.com)
- We screened a collection of essential genes to analyze the effects of core cellular processes in asymmetric cell division based on Ace2 localization. (figshare.com)
- While Pitx2 asymmetry drives many aspects of asymmetric morphogenesis, it is clear from published data that additional asymmetrically expressed loci must exist. (biomedcentral.com)
Caulobacter3
- When Caulobacter divides, it does so asymmetrically, producing daughter cells that have different fates. (the-scientist.com)
- Caulobacter asymmetrically divides to produce two types of daughter cells that are functionally and structurally different. (kenyon.edu)
- Caulobacter asymmetrically divides to produce a motile swarmer cell and a stalk cell. (kenyon.edu)
Symmetrically3
- In the latter case, an HSC could divide symmetrically (producing two HSCs) with probability p 2 , asymmetrically with probability p 1 , or produce two immature cells (progenitors) with probability p 0 . (aspetjournals.org)
- We found that although cell cytoplasm is divided symmetrically, mitochondria and membrane lipids are asymmetrically distributed between the two daughter cells and present a stable positive correlation with cytoplasm apportioning, which is incompatible with an independent division mechanism. (biorxiv.org)
- Committed OPCs divide either symmetrically to produce a pair of cycling OPCs or asymmetrically to give rise to one proliferated OPC and one differentiated OL. (uni-goettingen.de)
Bacterium1
- They are formed when the bacterium divides into two planes to form a square of four bacteria called a tetrad . (bioexplorer.net)
Single-celled1
- They are required for cell division, development, and movement in all organisms from single-celled species to human beings. (cshlpress.com)
Divisions4
- Similar to the PCP pathway, Disheveled proteins localize asymmetrically on the cell cortex before divisions, while, similar to the canonical Wnt pathway, b-catenin nuclear localization is regulated by the pathway. (irbbarcelona.org)
- Using the early embryonic divisions of the ascidian Phallusia mammillata as a model to investigate mechanisms of unequal cell division, this study convincingly demonstrates that cell shape and cortical domains are cooperating, rather than competing, in order to establish cell size asymmetry, a significant conceptual advance for the field. (elifesciences.org)
- We are studying the mechanisms of these unusual cell divisions, and how the way that the cells divide influences the structure and fate of daughter cells. (virginia.edu)
- In stage 3, the upper two cells divide asymmetrically, and the lower two cells undergo symmetric vertical divisions. (biomedcentral.com)
Germline1
- Germline stem cell (GSC) divides asymmetrically producing a gonioblast (GB). (biomedcentral.com)
Elegans3
- In C. elegans, most somatic cells divide asymmetrically through the function of Wnt signaling called Wnt Wnt/b-catenin asymmetry pathway. (irbbarcelona.org)
- Lecture and textbook material introduced me to experiments, but nothing could have conveyed the excitement and awe I felt watching that first division of the one cell C. elegans embryo. (ursinus.edu)
- Many of the 131 cells that are "programmed" to die during C. elegans development are the smaller daughter of a neuroblast that divides asymmetrically by size and fate. (ucl.ac.uk)
Stem cells3
- Profoundly different patterns of potency and division are exhibited by mammalian embryonic and adult stem cells. (iospress.com)
- Later, the stem cells divide asymmetrically, eventually generating billions of neurons and glia. (virginia.edu)
- The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells. (unibas.ch)
Cells divide asymmetrically2
- We have shown that epithelial cells divide asymmetrically along the axes of cell sheet displacement. (ous-research.no)
- How do neuronal precursor cells divide asymmetrically to produce post-mitotic sibling neurons of different fates? (wustl.edu)
Cortical1
- In the early embryo, a myosin II-dependent contraction of the cortical meshwork asymmetrically distributes the highly conserved PDZ proteins PAR-3 and PAR-6, as well as an atypical protein kinase C (PKC-3), to the anterior. (biologists.com)
Yeast1
- The budding yeast Saccharomyces cerevisiae divides asymmetrically, like many other cells, to generate two distinct progeny cells. (figshare.com)
Orthogonal3
- Due to the limited modulation bandwidth of the LED, orthogonal frequency division multiplexing (OFDM) modulation is particularly preferred in the VLC system to overcome the ISI, which suffers from the high peak-to-average power ratio (PAPR) and leads to severe performance loss. (hindawi.com)
- Orthogonal frequency division multiplexing (OFDM) has been proved particularly suitable for the VLC system, where the channel is decomposed into multiple frequency-flat channels, and the ISI can be eliminated [ 4 , 5 ]. (hindawi.com)
- In this paper, we proposed a novel peak to average power ratio (PAPR) reduction scheme for the asymmetrically clipped optical orthogonal frequency division multiplexing (ACO-OFDM) visible light communications system. (northumbria.ac.uk)
Stalk cell1
- That stalk cell will grow and at some point divide to produce another swarmer. (the-scientist.com)
Polarity2
- Cell division orientation is thought to result from a competition between cell geometry and polarity domains controlling the position of the mitotic spindle during mitosis. (elifesciences.org)
- It localizes asymmetrically to the posterior of the early embryo in a PKC-3-dependent manner, and functions redundantly with PAR-2 to maintain polarity. (biologists.com)
Mitotic1
- The latter grow in size, show high mitotic activity and an asymmetrical division mode. (biomedcentral.com)
Cell division6
- Shapiro identified positional information as a key research area, asking how spatial information is genetically encoded and translated, to create the three-dimensional organization of a cell and to form different daughter cells through cell division. (wikipedia.org)
- Whether and how such competition is also at work to determine unequal cell division (UCD), producing daughter cells of different size, remains unclear. (elifesciences.org)
- ecDNA replicate within cancer cells and can be passed to daughter cells asymmetrically during cell division, thereby constituting a primary driver of focal gene amplification and copy number heterogeneity in cancer. (businesswire.com)
- Our novel gene discoveries have led to cellular and molecular studies on topics such as cell division, cytokinesis, neuron polarization, and axon guidance. (virginia.edu)
- This means that CYCU;1 is involved in cell division in the dark phase. (bvsalud.org)
- Mutation of CYCU;1 leads to the failure of ECS to fully complete cell division in the dark phase, resulting in an enlargement of the cell size and a decrease in cell density, which is helpful to understand the function of CYCU;1 in the Nannochloropsis cell cycle. (bvsalud.org)
Possess the ability2
- Cells possess the ability to both divide and migrate concurrently during instances of wound healing, development, and cancer progression. (ous-research.no)
- Furthermore, a recent study reported that SP cells possess the ability to self-renew, and to divide asymmetrically into SP and non-SP cells [ 6 ]. (oncotarget.com)
Bacteria1
- This arrangement is formed when bacteria divide into three perpendicular planes forming packets of 8 or more cells. (bioexplorer.net)
Neuroblast1
- We have previously shown that CED-3 caspase is activated in such neuroblasts, and that before neuroblast division, a gradient of CED-3 caspase activity is formed in a ced-1 MEGF10 (multiple EGF-like domains 10)-dependent manner. (ucl.ac.uk)
Axis2
- The entry also provides a contrary sort of formality - no traditional hallway divides living and dining rooms, and guests enter the house asymmetrically, off axis, facing the living room fireplace. (centerbrook.com)
- In stage 1, the zygote divides asymmetrically along the apical-basal axis into two cells. (biomedcentral.com)
Developmental2
- Microscopy allows me to observe developmental timepoints and possible defects in the embryos, specifically during the first division. (ursinus.edu)
- If children cells after a division are not distinguishable, developmental trees are represented by the space \({\mathcal {T}}\) of rooted trees with possibly repeated labels, where all vertices are unordered. (biomedcentral.com)
Fate1
- By contrast,the other daughter cell asymmetrically acquired Numb, which inhibited Notch signaling, leading to a different fate choice. (biologists.com)
Embryo1
- The first time I looked into the microscope to watch the embryo divide asymmetrically with such purpose, I knew I was hooked. (ursinus.edu)
Mother cell1
- UCD divides the mother cell into two daughter cells of different sizes. (elifesciences.org)
Patterns1
- here, we use a combination of single-cell gene expression mapping and time-lapse imaging to identify individual MPs, their locations, movements and stereotyped patterns of division. (biologists.com)
Development2
- In summary, this paper describes the formation and division of MPs and multiple roles for Notch signaling in midline cell development, providing a foundation for comprehensive molecular analyses. (biologists.com)
- Overall, these findings emphasize that BAF complex is crucial for proper proliferative division and enhance of OPCs and IN differentiation during murine brain development. (uni-goettingen.de)
Molecular1
- In 1977, she became chair of the department of molecular biology and in 1981, director of Einstein's division of biological sciences. (wikipedia.org)
Ability1
- We now show that CED-3 caspase is necessary for the ability of neuroblasts to divide asymmetrically by size. (ucl.ac.uk)
Gene1
- A L-R expression screen identified the cytoskeletally-associated gene, actin binding lim protein 1 ( Ablim1 ), as asymmetrically expressed in both the node and left lateral plate mesoderm (LPM). (biomedcentral.com)
Primary1
- Historically, osteoarthritis has been divided into primary and secondary forms, although this division is somewhat artificial. (medscape.com)
Role1
- These results suggest a role for DNA replication in patterning epigenetic information in asymmetrically dividing cells in multicellular organisms. (sdbonline.org)
House1
- By extending the central section of gallery somewhat over the heads of the congregation we were enabled to bring Marklove's old Chestnut case to the front of the arcade and to house the new Great division within it. (cbfisk.com)
Equal1
- By now, you've heard the famous Rule of Thirds: divide the frame into nine equal parts with an imaginary tick-tack-toe grid. (videomaker.com)
Smaller1
- Analysis of muscle recruitment indicated that the demands of lifting asymmetrically are shifted to ancillary muscles possessing smaller cross-sectional areas, which may be at greater risk of injury during manual materials handling (MMH) tasks. (cdc.gov)
Provide1
- The Burn FO was designed asymmetrically to provide balance between flex, strength and recovery. (lax.com)
Balance1
- Δ = p 2 − p 0 corresponds to the balance between symmetrical and differentiated division. (aspetjournals.org)
Mode1
- We have studied the mode of division of B1 cells in juvenile mice. (idival.org)
Means1
- A green line between two cells means these two cells were just generated by a symmetric horizontal division. (biomedcentral.com)
Case2
- In case you don't know who Trevor is, he attended the University of Denver, where he set the NCAA Division I season record for face-off wins by a freshman. (lax.com)
- A new, diminutive case in Marklove's style adorns the balcony rail center and houses the new Choir, or Rückpositiv, division. (cbfisk.com)
Domains1
- The catalytic domains within a dimer are asymmetrically linked to the WAT/PRAD. (rcsb.org)
Numbers1
- Starting from the zygote, sea urchin and Arabidopsis thaliana are different in division plane and division symmetry, and the cell numbers at stage 4 are already different (16 vs. 14). (biomedcentral.com)
Projects1
- convergence between VE and DPT is called for, while acknowledging that this effort may demand new and more empirically well-informed projects on both sides of the division between Conservative VE (including the credit theory of knowing) and Autonomous VE (including accounts of epistemic responsibility and of guidance for improving practices of inquiry). (philpapers.org)