Asymmetric reactions asymmetric catalysis. Medical search. Frequent questions

We also have developed a novel, cyclic dipeptide catalyst (1) for an asymmetric variant of the Strecker amino acid synthesis. (purdue.edu)
We began with the synthesis of cyclic dipeptides 1 and 2 for our catalysis studies. (purdue.edu)
M.S Iyer, N. Namdev, K. Gigstad, and M.A.Lipton, "Asymmetric Catalysis of the Strecker Synthesis by a Cyclic Dipeptide," J. Am. Chem. (purdue.edu)
In recent years, enzymatic catalysis has emerged as an important alternative tool for the synthesis of enantiopure compounds. (europa.eu)
The research programme is focused on synthesis, catalysis, functional materials, bio-organic chemistry/chemical biology and systems chemistry/complex molecular systems. (noorderlink.nl)
A second part of the program deals with the development (and application in chemical biology) of novel stereoselective synthesis methods and asymmetric catalysis. (noorderlink.nl)
Enabled by a mild single electron transfer reduction of directly photoexcited catalyst/substrate complexes, the scope of asymmetric photocycloadditions is extended to simple mono-acceptor-substituted cyclopropanes with the synthesis of previously inaccessible enantioenhanced cyclopentane and cyclopentene derivatives. (uni-marburg.de)
Chapter III focuses on a stereodivergent synthesis of fluorinated lactams bearing two vicinal stereogenic centers by multicomponent reaction. (miun.se)
Poljak T, Molčanov K, Margetić D, Habuš I. Study on the Lewis Acid-promoted Aza-Diels - Alder Reaction of Azetidin-2-one-tethered Imines with Siloxydienes in the Asymmetric Synthesis of 2-Aryl(alkyl)-2,3-dihydro-4-pyridones. (srce.hr)
trans-3-Amino-b-lactams were evaluated as the chiral building blocks in the aza-Diels - Alder reaction of azetidin-2-one-tethered imines with siloxydienes under Lewis acid catalysis, as a route for the asymmetric synthesis of 2-aryl(alkyl)-2,3-dihydro-4-pyridones. (srce.hr)
The research in my group is primarily involved with the invention of new synthetic reactions, on the origin of stereocontrol in fundamental carbon-carbon and carbon-heteroatom bond forming reactions, and in the application of these developments to the synthesis of complex molecular structures. (illinois.edu)
The new method saves several synthesis steps and was long regarded as a 'desired reaction' in chemistry. (mpg.de)
Our research in organic chemistry is focused on the development of efficient synthetic methodologies related to the synthesis of physiologically important compounds and the advancement of chiral catalysts aimed at practical asymmetric synthesis. (snu.ac.kr)
Our chemists are well experienced with asymmetric synthesis using either chemical or enzymatic transformations at mg to multi gram scale. (gmkresearch.com)

Knowles, R. R. & Jacobsen, E. N. Attractive noncovalent interactions in asymmetric catalysis: links between enzymes and small molecule catalysts. (nature.com)
Multinuclear cobalt catalysts like (Co)4(CO)12 and Co3(CO)9(μ3-CH) suffer from the same flaw, although Takayama et al detail a reaction catalyzed by dicobalt octacarbonyl. (wikipedia.org)
To combine the advantages of these biological systems with the reactivity of artificial chemical catalysts, chemists have devised sequential, concurrent, and cooperative chemoenzymatic reactions that combine enzymatic and artificial catalysts1-9. (bvsalud.org)
However, such reactions are difficult to develop because chemical and enzymatic catalysts generally operate in different media at different temperatures and can deactivate each other1-9. (bvsalud.org)
1,2] In our latest publications, we reported the highest enantioselectivity for this reaction when using calcium as an environmentally friendly and inexpensive alternative to precious metal catalysts. (findaphd.com)
A major advance in the science of surface catalysis was the development of a method for determining the surface area of catalysts (and other materials) by measuring the multimolecular adsorption of nitrogen at liquid nitrogen temperatures or the adsorption of other gases close to their boiling points . (britannica.com)
Supramolecular catalysis, the use of non-covalent forces to affect a catalytic process, can afford the catalyst diversity required to uncover efficient catalysts and further our understanding. (unl.edu)
This has led to a broad effort directed toward the use of cyclic dipeptide catalysts (e.g., 2) in asymmetric carbon-carbon bond forming reactions. (purdue.edu)
Nevertheless, despite significant advances, it remains very difficult to predict the outcome of a metal-catalysed asymmetric reaction and, as a consequence, the number of efficient catalysts used for industrial applications remains low. (europa.eu)
This work was dedicated to the development and evaluation of new chiral catalysts for asymmetric C-C and C-H bond forming reactions. (cuvillier.de)
Tremendous progress continues to be made in the field of asymmetric catalysis, such as the development of new and better catalysts for the efficient construction of carbon-carbon and carbon-heteroatom bonds. (thieme.de)
In order to construct molecules that can form elastic and durable materials, store energy in batteries, or inhibit the progression of diseases, catalysts (substances that control and accelerate chemical reactions without being part of the final product) are required. (nordiclifescience.org)
The first one found to be efficient catalysts for the direct asymmetric aldol reaction between ketone and aromatic aldehydes. (ajgreenchem.com)

Asymmetric organocatalysis, cooperative dual catalysis and one-pot multicomponent reaction strategies were applied for the construction of continuous and quaternary stereogenic center. (miun.se)
Organocatalysis uses small organic molecules predominantly composed of C, H, O, N, S and P to accelerate chemical reactions. (organic-chemistry.org)
The Ph.D. researcher from Professor Benjamin List's Department of Homogeneous Catalysis at the Max-Planck-Institut für Kohlenforschung has found a very efficient way to synthesize the complex molecule from Neral using selective asymmetric organocatalysis. (mpg.de)
The Royal Swedish Academy of Sciences decided to award the Nobel Prize in Chemistry 2021 to Benjamin List and David MacMillan, for "the development of asymmetric organocatalysis. (nordiclifescience.org)
Using asymmetric organocatalysis, researchers today can more efficiently produce molecules and they also have a greener alternative for molecule production. (nordiclifescience.org)
The discovery of asymmetric organocatalysis began in the late 1990s. (nordiclifescience.org)
Princeton University professor David W.C. MacMillan has been awarded the 2021 Nobel Prize in chemistry "for the development of asymmetric organocatalysis. (princeton.edu)
Today the Royal Swedish Academy of Sciences highlighted his work in organocatalysis, finding revolutionary ways to design and build small organic molecules in order to drive chemical reactions. (princeton.edu)
Over the past 18 years, he has created two large and active fields of research: asymmetric organocatalysis and photoredox catalysis. (princeton.edu)

Martin Smith's group at the University of Oxford (UK) has been interested in the application of asymmetric phase-transfer catalysis to new reaction manifolds - particularly cyclizations - for some time. (thieme.de)
In recent years the tandem cycloaddition has been employed as a discovery engine for the investigation of structure/selectivity-reactivity relationships in asymmetric phase transfer catalysis with chiral quaternary ammonium ions. (illinois.edu)

When faced with unfamiliar reaction space, synthetic chemists typically apply the reported conditions (reagents, catalyst, solvent and additives) of a successful reaction to a desired, closely related reaction using a new substrate type. (nature.com)
This technique creates opportunities for translating comprehensive reaction analysis to diverse chemical space, streamlining both catalyst and reaction development. (nature.com)
Wilkinson's rhodium-based catalyst requires a silver triflate co-catalyst to effect the Pauson-Khand reaction: Molybdenum hexacarbonyl is a carbon monoxide donor in PK-type reactions between allenes and alkynes with dimethyl sulfoxide in toluene. (wikipedia.org)
List and co-workers report an asymmetric Mukaiyama aldolization controlled by a confined chiral imidodiphosphorimidate catalyst. (thieme-connect.com)
They include reactions between gases or liquids or both at the surface of a solid catalyst . (britannica.com)
Since heterogeneously catalyzed reactions occur on the surface of the catalyst, the rates of such reactions are proportional to the accessible surface area of the catalyst. (britannica.com)
Using a modular design and self-assembly, a large scale supramolecular catalyst screening in a catalyst scaffold optimization study of rhodium-catalyzed asymmetric hydrogenation was carried out. (unl.edu)
Jacobsen recalls Balskus's inventiveness and initiative, citing her novel idea of applying asymmetric catalysis-where a chiral catalyst aids in the formation of a favored stereoisomer-to control the formation of chemical bonds across large, cyclic molecules. (the-scientist.com)
In the first part of the thesis an ESI -MS screening method is described, which allows the determination of a chiral catalyst´s selectivity in the palladium catalyzed asymmetric allylic alkylation by testing its racemic form. (cuvillier.de)
During this work as well a new organo-catalyst, based on the structure of 2,3-dihydrobenzo[1,4]oxazine, was developed which allows for the asymmetric organo-catalyzed transfer-hydrogenation of α,β-unsaturated aldehydes. (cuvillier.de)
An intensive screening of both the organo-catalyst and the palladium-ligand led to reaction conditions which allowed for the selective mono-allylation of ketones in high yields. (cuvillier.de)
1) A bis-cyclometalated chiral-at-metal rhodium complex (designated as RhS) in combination with the photoredox catalyst [Ru(bpy)3](PF6)2 enables visible-light-activated asymmetric α-amination and α-alkylation of 2-acyl imidazoles with aryl azides or α-diazo carboxylic esters as radical precursors, respectively (Chapter 3.1). (uni-marburg.de)
3) A simple and robust catalysis scheme that only relies on a single bis-cyclometalated rhodium catalyst (RhS) is introduced to achieve the stereocontrol of bond forming reactions directly from an electronically excited state. (uni-marburg.de)
Coordination of the cyclopropane with the chiral catalyst generates the visible-light-absorbing complex, lowers the reduction potential of the cyclopropane, and provides the asymmetric induction and overall stereocontrol. (uni-marburg.de)
Moreover, it could be shown, that organic carbonates can be used to afford an efficient catalyst recycling as well as to obtain pure products via product distillation out of the reaction media. (uni-rostock.de)
He and his colleagues were redesigning antibodies so that they could drive chemical reactions, but List started wondering if a single amino acid could also work as a catalyst. (nordiclifescience.org)

These are known as heterogeneous catalytic reactions. (britannica.com)
finely divided metals, metal gauzes, metals incorporated into supporting matrices, and metallic films have all been used in modern heterogeneous catalysis. (britannica.com)
In the last decades the usefulness of these solvents for homogeneous and heterogeneous catalysis has been presented in several publications. (uni-rostock.de)

New approaches to the development of chemoenzymatic reactions are needed to enable valuable chemical transformations beyond this scope. (bvsalud.org)
In particular, photoredox catalysis affords facile access to a plethora of transformations that were previously thought to be impossible. (beilstein-journals.org)
Driving asymmetric catalysis with visible light or electricity is of significant value because they represent 'green' and sustainable methods to synthesize non-racemic chiral molecules and in addition offer ample opportunities for chemists to discover new mechanistic scenarios and invent previously unknown transformations. (uni-marburg.de)
In the third part, we reported a class of reactions involving C-H cleavage under mild conditions: Pd II -catalyzed oxidative transformations of enallenes. (diva-portal.org)
These reports introduced highly enantioselective transformations that rivaled the metal-catalyzed reactions in both yields and selectivity. (organic-chemistry.org)
They have been used in a variety of carbonyl compound transformations, where the catalysis is believed to involve the iminium form. (organic-chemistry.org)
The reaction features the first triple metal-catalyzed transformations in one reaction vessel, without any intermediate workup. (blogspot.com)

As a validating case study, we combined published enantioselectivity datasets that employ 1,1′-bi-2-naphthol (BINOL)-derived chiral phosphoric acids for a range of nucleophilic addition reactions to imines and developed statistical models. (nature.com)
Perhaps most surprisingly, the presence of a chiral recognition element positioned remote to the site of catalysis can significantly impact the catalytic activity and enantioselectivity. (unl.edu)

He is also a leader in the field of photoredox catalysis, which uses light - ordinary, visible light - to break and rejoin atomic bonds, one electron at a time. (princeton.edu)

Hameršak, Z., Dokli, I. & Ivšić, T. (2016) Chapter 15:Nonquaternised Cinchona Alkaloid Derivatives as Asymmetric Organocatalysts for Carbon-Heteroatom Bond-forming Reactions . (irb.hr)

Consequently, an important goal in synthetic chemistry is the ability to transfer chemical observations quantitatively from one reaction to another. (nature.com)
The research interests of the members of the Chemical Physics Thematic Research Group are diverse, with groups focusing on high-end laser and NMR spectroscopies, kinetics and modelling of atmospheric chemical reactions, experimental and theoretical biophysical chemistry, polymers at interfaces, and statistical and quantum mechanics. (mcgill.ca)
The utilization of light to induce or accelerate a chemical reaction is undoubtedly one of the most promising and sustainable fields in modern organic chemistry. (beilstein-journals.org)
Inspired by Nature's principles of molecular assembly, recognition, transport, motion and catalysis, the goal is to exploit the full potential of synthetic chemistry to create new structures and functions. (noorderlink.nl)
Controlling the stereochemical outcome of radical-mediated reactions has been a challenge in synthetic chemistry and asymmetric catalysis. (ucsb.edu)
Detailed kinetic and mechanistic investigations in our group aim to blend the quantitative aspects of chemical engineering together with organic chemistry to achieve a fundamental understanding of complex catalytic reaction networks, particularly in asymmetric catalysis. (imperial.ac.uk)
Reaction chemistry & engineering, 8 (3), 673-686 doi:10.1039/D2RE00461E. (irb.hr)
Stereocontrolled cyclization reactions represent formidable tools for constructing complex structural scaffolds of natural and biologically active molecules and the development of new cyclization methodologies continues to attract enormous interest in organic chemistry. (thieme.de)
This concept for catalysis is as simple as it is ingenious, and the fact is that many people have wondered why we didn't think of it earlier," said Johan Åqvist, Chair of the Nobel Committee for Chemistry, after the announcement. (nordiclifescience.org)
Highly asymmetric aldol reaction of cyclohexanone and aromatic aldehydes catalyzed by bifunctional cyclohexane derived thiourea organocatalyst', Asian Journal of Green Chemistry , 3(2), pp. 201-215. (ajgreenchem.com)

The last part of this work aimed for the asymmetric α -allylation of carbonyl compounds by a tandem-catalysis approach. (cuvillier.de)
In recent years this interest has focused on palladium catalyzed cross-coupling reactions with organofunctional silicon compounds, asymmetric catalysis of carbonyl and olefin addition reactions and chiral Lewis base activation of Lewis acids. (illinois.edu)

Many HPAPIs are synthesized through multiple process steps which require advanced technologies, such as peptide coupling, mPEG/PEGylation, continuous processing, chiral resolution, catalysis or biocatalysis, and cryogenic reactions. (evonik.com)
there were metals (metal catalysis) and there were enzymes (biocatalysis). (nordiclifescience.org)

Living organisms rely on simultaneous reactions catalysed by mutually compatible and selective enzymes to synthesize complex natural products and other metabolites. (bvsalud.org)
More generally, these results show that the compatibility between photocatalysts and enzymes enables chemoenzymatic processes beyond cofactor regeneration and provides a general strategy for converting stereoselective enzymatic reactions into stereoconvergent ones. (bvsalud.org)

He tested if proline could catalyze an aldol reaction, in which carbon atoms from two different molecules are bonded together. (nordiclifescience.org)

By this all reaction intermediates postulated for an enamine mechanism have been detected. (cuvillier.de)
Chapter IV illustrates a new enantioselective allylic alkylation of acetonide protected trioses and furanosides by merging enamine catalysis with transition metal catalysis. (miun.se)

Cooperative asymmetric reactions combining photocatalysis and enzymatic catalysis. (bvsalud.org)
Owing to these constraints, the vast majority of cooperative chemoenzymatic processes that have been reported over the past 30 years can be divided into just two categories chemoenzymatic dynamic kinetic resolutions of racemic alcohols and amines , and enzymatic reactions requiring the simultaneous regeneration of a cofactor2,4,5. (bvsalud.org)
From these considerations, it appears that homogeneous and enzymatic catalyses are in many respects complementary. (europa.eu)

This reaction occurred under environmentally benign and external oxidant-free reaction conditions with good functional group compatibility. (organic-chemistry.org)

Sulfur compounds are typically hard to handle and smelly, but n-dodecyl methyl sulfide and tetramethylthiourea do not suffer from those problems and can improve reaction performance. (wikipedia.org)
In the second part new PHOX -type ligands were tested in the iridium-catalyzed asymmetric hydrogenation of different unsaturated compounds. (cuvillier.de)

C-Terminal modification of peptides and proteins using organophotoredox catalysis. (beilstein-journals.org)
The combination of organophotoredox catalysis with hydrogen atom transfer enables a mild C-H alkylation of quinoxalin-2(1 H )-ones with feedstock aldehydes, amides, alcohols, ethers, or cycloalkanes. (organic-chemistry.org)

My Research interests focus on studies of complex catalytic organic reactions, with emphasis on application in pharmaceutical processes. (imperial.ac.uk)
This thesis presents the use of organic carbonates (especially propylene carbonate) as alternative solvents for asymmetric catalysis. (uni-rostock.de)
In this thesis homogeneous palladium-, rhodium- and iridium-catalyzed reactions were investigated in organic carbonates. (uni-rostock.de)
Furthermore this thesis includes results on the use of organic carbonates as solvents for palladium catalyzed copper-free Sonogashira reaction as well as for asymmetric allylic substitutions. (uni-rostock.de)
In recent years, my group has investigated theuse of chemoinformatics and machine learning to identify and optimize catalystsfor a variety of organic and organometallic reactions. (illinois.edu)
For one of his first experiments, MacMillan needed an organic molecule that could catalyze a reaction that formed an iminium ion. (nordiclifescience.org)

Based on experimental results and DFT calculation, transition states were proposed to explain the stereoselectivity of the reaction. (organic-chemistry.org)

Furthermore air- and moisture-stable secondary phosphine oxide ( SPO ) containing bidentate ligands were tested in the palladium-catalyzed asymmetric allylic alkylation reaction. (cuvillier.de)

My group maintains a long-standing interest in catalytic enantioselective reactions with organozinc and other organometallic reagents. (illinois.edu)

and β-amino aldehydes by proline-catalyzed Mannich reaction. (sigmaaldrich.com)
Moreover an ESI -MS based mechanistic study on the tripeptide catalyzed conjugate addition reaction of aldehydes to nitroolefins was carried out. (cuvillier.de)

Chiral self-replication is one approach that will be followed using condensation reactions and supramolecular assembly. (noorderlink.nl)

The Pauson-Khand (PK) reaction is a chemical reaction, described as a [2+2+1] cycloaddition. (wikipedia.org)

Homogenous gold catalysis has made significant progress in recent years, but gold has been rarely used in CADA reactions compared with other transition metals. (chemistryviews.org)
Sustainable Catalysis : Without Metals or Other Endangered Elements, Part 2. (irb.hr)

Rh-catalyzed asymmetric hydrogenation has emerged as a powerful tool for the manufacturing of chiral pharmaceuticals. (unl.edu)

N-heterocyclic carbenes (NHCs) are commonly used ligands in transition-metal catalysis. (chemistryviews.org)
Transition-metal-catalyzed C-C coupling reactions, such as the catalytic asymmetric dearomatization (CADA) reaction, are useful tools to synthesize complex molecules efficiently. (chemistryviews.org)

Before scientists were able to perform asymmetric catalysis, many medicines contained both mirror images of a molecule. (nordiclifescience.org)
I, II, and III, all with one BPTI molecule per asymmetric unit in solution. (lu.se)

Asymmetric Chiral-at-Rhodium C. (uni-marburg.de)

The reaction starts with dicobalt hexacarbonyl acetylene complex. (wikipedia.org)
Creating complex polycyclic molecules from simple building blocks often is challenging and requires many reaction steps. (chemistryviews.org)

Alternatively, asymmetric autocatalysis will be explored using simple cyclic and acyclic acceptor molecules and amine donors to generate e.g. amino acids. (noorderlink.nl)
The reaction could be a basis for new syntheses of cyclic and polycyclic molecules. (chemistryviews.org)

In the final part, we developed the carbonylative insertion reaction discussed in the third part of the thesis into an asymmetric version. (diva-portal.org)

Sharpless's Epoxidation, Dihydroxylation (AD)/Aminohydroxylation (AA) & Jacobsen's hydrolytic kinetic resolution, and Reduction reactions (e.g. (gmkresearch.com)

A copper-catalyzed asymmetric conjugate borylation (ACB) reaction was used to investigate the applicability of the Cholest CAAC as a stereo-directing chiral ligand. (chemistryviews.org)
The conjugate-addition/amidation/amidation reaction sequence is highly modular, divergent, and practical. (blogspot.com)

Generally, the reaction is highly syn-selective about the bridgehead hydrogen and substituents on the cyclopentane. (wikipedia.org)
Conﬁnement-Controlled, either syn - or anti -Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes. (thieme-connect.com)
SPO ,P ligands however, were able to promote the desired reaction in a highly selective fashion although only low activities were found. (cuvillier.de)

out regioselective acylation reactions. (researchgate.net)

With unsymmetrical alkenes or alkynes, the reaction is rarely regioselective, although some patterns can be observed. (wikipedia.org)
Here we report a class of cooperative chemoenzymatic reaction that combines photocatalysts that isomerize alkenes with ene- reductases that reduce carbon - carbon double bonds to generate valuable enantioenriched products. (bvsalud.org)
1,1-Disubstituted alkenes are a challenging class of substrates for the asymmetric hydroboration reaction. (unl.edu)

Davis, H. J. & Phipps, R. J. Harnessing non-covalent interactions to exert control over regioselectivity and site-selectivity in catalytic reactions. (nature.com)
Pauson and Khand's initial findings were intermolecular in nature, but the reaction has poor selectivity. (wikipedia.org)
The reaction's poor selectivity is ameliorated in intramolecular reactions. (wikipedia.org)
Professor Jeffrey Johnson at the University of North Carolina at Chapel Hill (USA) pointed out that reaction design tends to focus on how to maximize kinetic selectivity in the bond-forming step, while considerations around post-reaction processing (e.g. purifications) tend to receive less attention. (thieme.de)

Appropriate chiral ligands or auxiliaries can make the reaction enantioselective (see § Amine N-oxides). (wikipedia.org)
In order to achieve our aims in catalysis, a significant amount of effort is spent on the development of new chiral ligands: we have recently reported a general route to a class of N-functionalised ethylene diamines,[1] which can be employed either as ligands in their own right, or as precursors for preparing imidazoline ligands. (findaphd.com)

One of our recent highlights has been the development of chiral calcium complexes for the asymmetric hydroamination of amino-olefins. (findaphd.com)

To be efficient catalytically, a process must involve energies of activation for all the steps involved that, at their maxima, are less than those required for the uncatalyzed reaction. (britannica.com)
He mentioned that "The result of this prioritization is that even for highly efficient reactions, significant time and resources must be spent on isolation of the desired product, which limits the potential application on large scale or in other laboratories without the appropriate equipment. (thieme.de)

Unfortunately, this approach often fails owing to subtle differences in reaction requirements. (nature.com)
Robbins, D. W. & Hartwig, J. F. A simple, multidimensional approach to high-throughput discovery of catalytic reactions. (nature.com)
The use of chiral ammonium salts turned out to discriminate between the π-faces of a delocalized anion, which offered an approach to asymmetric electrocyclic reactions. (thieme.de)

In the Morita-Baylis-Hillman (MBH) reactions of arylaldehydes with methyl vinyl ketone, it was observed that in the presence of a catalytic amount of a chiral phosphine Lewis base (CPLB) bearing multiple phenol groups, such as CPLB1 (10 mol %), the corresponding MBH adducts could be obtained in moderate to good yields with low to moderate ee's (4-45% ee) at ambient temperature (10 degrees C) in THF. (unboundmedicine.com)

McNally, A., Prier, C. K. & MacMillan, D. W. C. Discovery of an alpha-C-H arylation reaction using the strategy of accelerated serendipity. (nature.com)
In short, as MacMillan described in his Nobel lecture, asymmetric catalysis could be described as the science of making molecules as one mirror image instead of the other. (nordiclifescience.org)
MacMillan is an innovator, pursuing radically new concepts in catalysis . (princeton.edu)

Organisms1

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Phenomena and Processes9

Disciplines and Occupations1

Information Science2

Synthesis14

Catalysts13

Organocatalysis9

Phase transfer2

Catalyst16

Heterogeneous3

Transformations7

Enantioselectivity2

Photoredox catalysis1

Carbon-Heteroatom Bond-forming R1

Chemistry10

Carbonyl2

Biocatalysis2

Enzymes2

Aldol1

Enamine2

Enzymatic3

Environmentally benign1

Compounds2

Organophotoredox2

Organic6

Stereoselectivity1

Allylic1

Reagents1

Aldehydes2

Supramolecular1

Cycloaddition1

Metals2

Hydrogenation1

Transition2

Molecule2

Rhodium1

Complex2

Cyclic2

Thesis1

Dihydroxylation1

Conjugate2

Selective3

Acylation1

Alkenes3

Selectivity4

Ligands2

Complexes1

Efficient2

Approach3

Phosphine1

MacMillan3