• Eosinophilia may often be seen in the bronchoalveolar lavage fluid in patients with desquamative interstitial pneumonitis. (medscape.com)
  • During the acute phase of the infection (28-35 days), a process of multifocal interstitial pneumonitis involving the peribronchial, peribronchiolar and subpleural tissues was found. (rsbmt.org.br)
  • The pneumonitis was attributed to products (inflammatory mediators) from acute-phase periovular necrotic-inflammatory lesions in the liver that were transported to the lungs by the bloodstream. (rsbmt.org.br)
  • HRCT of lung showing extensive fibrosis possibly from usual interstitial pneumonitis. (iiab.me)
  • Approach to Parasitic Infections Human parasites are organisms that live on or in a person and derive nutrients from that person (its host). (msdmanuals.com)
  • Parasitic infections of the lung: a guide for the respiratory physician. (medscape.com)
  • This department provides medical care for patients with bronchial, lung and pleural tumors, respiratory tract infections, pulmonary vascular lesions, and respiratory failure. (japanhospitalsearch.org)
  • close physical proximity (OR 1.54, 95% CI 1.45 to 1.62) and high exposure to diseases or infections (OR 1.54, 95% CI 1.44 to 1.64). (bvsalud.org)
  • Infection to the vagina or genital tract caused by E.coli etc called gynecological infections includes endometriosis, pelvic inflammatory diseases, etc. (drugcarts.com)
  • Examples include autoimmune disorders , viral infections and bacterial infection like tuberculosis which may cause fibrotic changes in both lung's upper or lower lobes and other microscopic injuries to the lung. (iiab.me)
  • In some syndromes, such as tropical pulmonary eosinophilia (TPE) and chronic eosinophilic pneumonia (CEP), interstitial fibrosis may result from chronic inflammation. (medscape.com)
  • In this context, identification of eosinophilic pneumonia in lung biopsies may be helpful in the diagnosis and classification of these syndromes when the clinical features are atypical. (medscape.com)
  • Idiopathic chronic eosinophilic pneumonia is reported to comprise anywhere from 0-2.5% of cases within the registries of interstitial lung disease. (medscape.com)
  • Little information is available regarding the prevalence and incidence of eosinophilic reactions to drugs or as a secondary histologic manifestation of pulmonary infection, parasitic infection (eg, Löffler syndrome, simple eosinophilic pneumonia), or neoplasia or as a component of Churg-Strauss syndrome. (medscape.com)
  • Ozdemir O. Loeffler's syndrome: a type of eosinophilic pneumonia mimicking community-acquired pneumonia and asthma that arises from Ascaris lumbricoides in a child. (medscape.com)
  • This is a diagnosis of exclusion of a characteristic set of histologic/pathologic features known as usual interstitial pneumonia (UIP). (iiab.me)
  • Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli . (wikizero.com)
  • [8] The disease may be classified by where it was acquired, such as community- or hospital-acquired or healthcare-associated pneumonia. (wikizero.com)
  • Risk factors for pneumonia include cystic fibrosis , chronic obstructive pulmonary disease (COPD), sickle cell disease , asthma , diabetes , heart failure, a history of smoking, a poor ability to cough (such as following a stroke), and a weak immune system . (wikizero.com)
  • [22] Bloody sputum (known as hemoptysis ) may also occur with tuberculosis , Gram-negative pneumonia, lung abscesses and more commonly acute bronchitis . (wikizero.com)
  • The increased leukotriene concentration significantly correlated with diffusing capacity of the lung for carbon monoxide, suggesting that the monitoring of leukotriene concentration may aid in the management of eosinophilic pneumonia patients. (ersjournals.com)
  • Eosinophilic pneumonia (EP) is a diffuse infiltrative lung disease characterised by alveolar and peripheral airway eosinophilia 1 - 4 . (ersjournals.com)
  • Lung involvement may manifest as shortness of breath, interstitial lung disease, pleural effusion, and even respiratory failure. (wikipedia.org)
  • Asthma is characterized by recurrent episodes of wheezing , shortness of breath , chest tightness , and coughing . (mdwiki.org)
  • While this zoonotic infection is usually asymptomatic, it may cause severe disease. (wikipedia.org)
  • Physiological reactions to Toxocara infection depend on the host's immune response and the parasitic load. (wikipedia.org)
  • High parasitic loads or repeated infection can lead to visceral larva migrans (VLM). (wikipedia.org)
  • There was no evidence that the lung damage could be due to bacterial infection, the authors note. (helpsleddogs.org)
  • Mainly this bacterial infection targets the lungs and urinary tract. (drugcarts.com)
  • Infection and inflammation to the respiratory air sacs of lungs. (drugcarts.com)
  • Disruption of the lung endothelial-epithelial cell barrier following respiratory virus infection causes cell and fluid accumulation in the air spaces and compromises vital gas exchange function1. (bvsalud.org)
  • Finally, we show that protective AHR signalling in lung endothelial cells is dampened by the infection itself. (bvsalud.org)
  • The airway inflammation of chronic obstructive pulmonary disease (COPD) is largely neutrophilic, but 20-40% of induced sputum samples from individuals with stable COPD have eosinophilic airway inflammation, associated with elevated levels of sputum interleukin (IL)-5. (medscape.com)
  • Dry cough, dyspnea and manifestations of bronchial asthma have recently been observed in patients with acute schistosomiasis. (rsbmt.org.br)
  • Dry cough and episodes of bronchial asthma are frequently registered, accompanied by high production of inflammatory cytokines, such as IL-1, IL-6 and TNF α 8 . (rsbmt.org.br)
  • In cats with orthopnoea the main considerations are severe asthma and pleural effusion (usually cardiac), but orthopnoea in dogs can be due to a variety of respiratory diseases and severe pulmonary oedema. (vin.com)
  • Hyperpnoea is more likely to be associated with severe pulmonary oedema or pleural effusion, as severe respiratory disease cases tend to adopt a slow purposeful deep respiratory pattern (true laboured breathing) to improve ventilation, but with minor stress breathing can become rapid and laboured. (vin.com)
  • OBJECTIVE: We sought to determine the role of A20 in the regulation of IL-33 signaling in macrophages and IL-33-induced lung immunity. (bvsalud.org)
  • RESULTS: IL-33-induced lung innate lymphoid cell type 2 expansion, type 2 cytokine production, and eosinophilia were drastically reduced in the absence of macrophage A20 expression, whereas neutrophils and interstitial macrophages in lungs were increased. (bvsalud.org)
  • Alveolar macrophages (AMs) are the tissue-resident macrophages in the lung alveolar space. (frontiersin.org)
  • In genetically susceptible individuals, these interactions can lead the patient with asthma to symptoms of breathlessness, wheezing, cough, and chest tightness. (medscape.com)
  • In North Carolina, a reported increase in persons presenting with asthma symptoms was postulated to be caused by exposure to mold ( 2 ). (cdc.gov)
  • [4] Diagnosis is generally based on the pattern of symptoms, response to therapy over time, and spirometry lung function testing. (mdwiki.org)
  • [2] Asthma is classified according to the frequency of symptoms, forced expiratory volume in one second (FEV1), and peak expiratory flow rate . (mdwiki.org)
  • [15] Some people with asthma rarely experience symptoms, usually in response to triggers, whereas others may react frequently and readily and experience persistent symptoms. (mdwiki.org)
  • Successful anti-inflammatory therapy leads to long-term prevention of the symptoms of asthma by suppressing, controlling, and reversing inflammation. (respiratory-therapy.com)
  • The airflow obstruction produces the signs and symptoms of asthma: coughing, wheezing, dyspnea, and a sensation of chest tightness. (respiratory-therapy.com)
  • Co-morbidities of asthma include sinusitis, nasal polyposis, gastro-esophageal reflux disease (GERD) and allergic rhinitis. (medscape.com)
  • A number of other health conditions occur more frequently in people with asthma, including gastro-esophageal reflux disease (GERD), rhinosinusitis , and obstructive sleep apnea . (mdwiki.org)
  • Classic occupational interstitial lung diseases such as asbestosis, silicosis, and coal workers' pneumoconiosis still comprise a substantial burden of disease in modern industrial societies, while other occupational causes of pulmonary fibrosis and granulomatous inflammation are frequently misclassified as idiopathic. (bvsalud.org)
  • Pulmonary fibrosis (literally "scarring and damage of the lungs ") is a respiratory disease in which scars are formed in the lung tissues, leading to serious breathing problems. (iiab.me)
  • In some cases the specific cause of the disease can be diagnosed, but in others the probable cause cannot be determined, a condition called idiopathic pulmonary fibrosis . (iiab.me)
  • There is no known cure for the scars and damage in the lung due to pulmonary fibrosis. (iiab.me)
  • Pulmonary fibrosis may be a secondary effect of other diseases. (iiab.me)
  • Pulmonary fibrosis involves gradual exchange of normal lung parenchyma with fibrotic tissue. (iiab.me)
  • The replacement of normal lung with scar tissue causes irreversible decrease in oxygen diffusion capacity, and the resulting stiffness or decreased compliance makes pulmonary fibrosis a restrictive lung disease . (iiab.me)
  • In contrast, quadriplegia [12] and kyphosis [13] are examples of causes of restrictive lung disease that do not necessarily involve pulmonary fibrosis. (iiab.me)
  • The removed tissue is examined histopathologically by microscopy to confirm the presence and pattern of fibrosis as well as presence of other features that may indicate a specific cause e.g. specific types of mineral dust or possible response to therapy e.g. a pattern of so-called non-specific interstitial fibrosis. (iiab.me)
  • This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint providership of Medscape, LLC and Emerging Infectious Diseases. (cdc.gov)
  • They provide specialized treatment for conditions like asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. (wikimd.com)
  • Asthma is a clinical syndrome characterized by episodic reversible airway obstruction, increased bronchial reactivity, and airway inflammation. (medscape.com)
  • 1 Lung biopsy and bronchoalveolar lavage in patients with stable asthma show the presence of inflammation consistent with a late-phase reaction, whereas pulmonary-function tests show hyperresponsiveness of the airway that is proportional to the magnitude of the late-phase reaction. (respiratory-therapy.com)
  • Although the mechanisms of eosinophilic accumulation remain to be elucidated, increasing evidence suggests the important roles of cytokine, chemokine and lipid mediators in the regulation of eosinophilic inflammation in various eosinophilic airway diseases 5 . (ersjournals.com)
  • Migrating parasites traversing the lungs may cause bronchospasm, dyspnea, and pulmonary infiltrates. (medscape.com)
  • Pulmonary diseases associated with tissue and/or blood eosinophilia are a heterogeneous group of disorders. (medscape.com)
  • They are sometimes referred to as rheumatic diseases, connective tissue disorders, or collagen vascular disorders. (ssa.gov)
  • Other diseases that involve connective tissue, such as sarcoidosis and granulomatosis with polyangiitis . (iiab.me)
  • This department provides medical care for patients with acute and chronic kidney diseases, kidney failure, dysfunction and tumors of endocrine organs, and hypertension. (japanhospitalsearch.org)
  • Clinical studies on these new cases of acute schistosomiasis have been revealing intriguing manifestations related to the immunopathology of the disease. (rsbmt.org.br)
  • Acute schistosomiasis is related to the migration of parasite larvae through the lungs and a rise in the host immune response towards parasite larvae, worms and eggs. (rsbmt.org.br)
  • The urinary LTE 4 concentration significantly correlated with the diffusing capacity of the lung for carbon monoxide in EP patients during acute exacerbation. (ersjournals.com)
  • Cardiac and respiratory diseases have many common features which can make diagnosis problematic. (vin.com)
  • The diagnosis can be confirmed by lung biopsy . (iiab.me)
  • Pulmonology is a specialized field in medicine that delves into the study, diagnosis, treatment, and prevention of diseases and conditions related to the lungs. (wikimd.com)
  • Large cells, usually multinucleate, whose presence is a common histologic characteristic of classical HODGKIN DISEASE. (lookformedical.com)
  • Worldwide, economic costs for asthma are more than those for tuberculosis and acquired immunodeficiency syndrome (AIDS) combined. (medscape.com)
  • On its release from lung epithelial cells, IL-33 primarily drives type 2 immune responses, accompanied by eosinophilia and robust production of IL-4, IL-5, and IL-13. (bvsalud.org)
  • The key inflammatory cells involved in the genesis of asthma are mast cells, eosinophils, lymphocytes, and epithelial cells. (respiratory-therapy.com)
  • Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. (lookformedical.com)
  • The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. (lookformedical.com)
  • [11] It is the main cause of restrictive lung disease that is intrinsic to the lung parenchyma. (iiab.me)
  • In other inflammatory diseases associated with eosinophilia, such as allergic asthma, aspirin-intolerant asthma and nasal polyposis, local eosinophil accumulation closely correlates with tissue cysteinyl LT (CysLT) concentration 9 , 10 . (ersjournals.com)
  • In contrast, cats rarely cough with heart disease, and if coughing is present in cardiac cases it is usually presumed to indicate that concurrent respiratory disease is present. (vin.com)
  • A harsh cough is more likely to be respiratory, but soft coughing can be due either to pulmonary oedema or lung parenchymal disease. (vin.com)
  • Asthma results from complex interactions among inflammatory cells, their mediators, airway epithelium and smooth muscle, and the nervous system. (medscape.com)
  • CONCLUSIONS: Racing Alaskan sled dogs have airway dysfunction similar to 'ski asthma' that persists despite having 4 months of rest. (helpsleddogs.org)
  • These findings suggest that repeated exercise in cold conditions can lead to airway disease that does not readily resolve with cessation of exercise. (helpsleddogs.org)
  • In subjects with asthma, there is a correlation between serum IgE concentrations and both airway responsiveness and the number of high-affinity receptors. (respiratory-therapy.com)
  • Eosinophilia and pulmonary infiltrates have been reported in patients with AIDS, lymphoma, a variety of inflammatory lung diseases, and collagen vascular diseases (see Etiology ). (medscape.com)
  • Asthma may manifest with marked eosinophilia, with or without infiltrates. (medscape.com)
  • The subjects included individuals with at least 1 encounter with an International Classification of Diseases, Ninth Revision, Clinical Modification code of 359.21. (cdc.gov)
  • During hyperinfection, large numbers of larvae gain access to the bloodstream, lungs, central nervous system, and other organs. (msdmanuals.com)
  • Strongyloides larvae penetrate human skin, migrate via the bloodstream to the lungs, break through pulmonary capillaries, ascend the respiratory tract, are swallowed, and reach the intestine, where they mature in about 2 weeks. (msdmanuals.com)
  • Occasionally, crackles or wheezes may be heard on lung auscultation. (medscape.com)
  • Sometimes fine inspiratory crackles can be heard at the lung bases on auscultation. (iiab.me)
  • AIM: To explore the experiences of healthcare workers (HCWs) following occupational exposure to coronavirus disease 2019 (COVID-19) during the early stage of the pandemic. (bvsalud.org)
  • In 2019, 262 million people globally had asthma, up from 183 million in 1990. (mdwiki.org)
  • These respiratory manifestations have been attributed to an allergic reaction caused by the passage of parasite larvae, but recent functional studies have revealed that the pulmonary involvement is predominantly interstitial, and more related to the levels of immune complexes than to IgE serum levels 7 . (rsbmt.org.br)
  • Among occupational cancers, lung cancer is the most common, and is associated with more than 10 important workplace carcinogens. (bvsalud.org)
  • Here we investigate lung-resident B cell responses in patients from the TRACERx 421 (Tracking Non-Small-Cell Lung Cancer Evolution Through Therapy) and other lung cancer cohorts, and in a recently established immunogenic mouse model for lung adenocarcinoma3. (bvsalud.org)
  • BACKGROUND: IL-33 plays a major role in the pathogenesis of allergic diseases such as asthma and atopic dermatitis. (bvsalud.org)
  • Allergic diseases are characterized by biphasic reactions mediated by immunoglobulin E (IgE). (respiratory-therapy.com)
  • Effective allergen immunotherapy attenuates the late-phase reaction, but immunotherapy has not been uniformly effective in the treatment of asthma and other allergic diseases. (respiratory-therapy.com)
  • At the cellular level, the inflammatory response in asthma is similar to that in other allergic diseases. (respiratory-therapy.com)
  • [ 7 ] Using a cross-sectional design, the authors compared children living on farms to those in a reference group with respect to the prevalence of asthma and to the diversity of microbial exposure. (medscape.com)
  • The studies found that children who lived on farms had a lower prevalence of asthma and atopy and were exposed to a greater variety of environmental microorganisms than children in the reference group. (medscape.com)
  • The prevalence of asthma and allergic sensitization was 4 and 6 times lower in the Amish population, with higher median endotoxin levels in house dust. (medscape.com)
  • One impressive new development has been a drastic reduction in the incidence and prevalence of the most advanced forms of the disease, such as the hepatosplenic form, and its complications 1 . (rsbmt.org.br)
  • According to the latest surveillance information 6 from the US National Institutes of Health, the prevalence rates for asthma are increasing for individuals of all ages. (respiratory-therapy.com)
  • Children and young adults not only have the greatest relative prevalence of asthma, but it is in this group that prevalence is increasing at the most rapid rate. (respiratory-therapy.com)
  • We focus on occupational chronic respiratory disease of which chronic obstructive lung disease and asthma are the most significant. (bvsalud.org)
  • Initial chest radiograph of a 54-year-old man showing subtle opacity (arrows) in the right middle lung zone. (medscape.com)
  • This kind of biopsy involves placement of several tubes through the chest wall, one of which is used to cut off a piece of lung to send for evaluation. (iiab.me)
  • Coughing is a cardinal sign of respiratory disease in the dog and cat, but in the dog it is also commonly seen with cardiac disease. (vin.com)
  • Here we show that the environmental sensor aryl hydrocarbon receptor (AHR) is highly active in lung endothelial cells and protects against influenza-induced lung vascular leakage. (bvsalud.org)
  • We implemented our method on 457 CEQTs for association with family history of diabetes, asthma, and coronary heart disease (CHD) in 42,940 adults spanning 8 waves of the 1999-2014 National Health and Nutrition Examination Survey (NHANES). (cdc.gov)
  • We identified 172 (37.6% of total), 32 (7.0%), and 78 (17.1%) CEQTs associated with family history of diabetes, asthma, and CHD, respectively, in sub-cohorts of individuals without the respective disease. (cdc.gov)
  • 20 associated CEQTs were shared across family history of diabetes, asthma, and CHD, far more than expected by chance. (cdc.gov)
  • This department provides preventive care and treatment for diseases such as diabetes, dyslipidemia, obesity, and metabolic syndrome, which have been proliferating as lifestyles change. (japanhospitalsearch.org)
  • Risk factors for asthma include a family history of allergic disease, the presence of allergen-specific immunoglobulin E (IgE), viral respiratory illnesses , exposure to aeroallergens , cigarette smoke, obesity , and lower socioeconomic status. (medscape.com)
  • Endothelial dysfunction can exacerbate tissue damage2,3, yet it is unclear whether the lung endothelium promotes host resistance against viral pathogens. (bvsalud.org)
  • We identify a gut-lung axis that affects lung damage following encounters with viral pathogens, linking dietary composition and intake to host fitness and inter-individual variations in disease outcome. (bvsalud.org)
  • Glucocorticoids (GCs) are widely prescribed therapeutics for the treatment of inflammatory diseases, and endogenous GCs play a key role in immune regulation. (frontiersin.org)
  • Analyses of publicly available datasets suggested that TLR2 is induced during the resolution phase of inflammatory diseases, i.e., under conditions associated with high endogenous GC production. (frontiersin.org)
  • [ 3 ] In Western countries, the financial burden on patients ranges from $300 to $1,300 per patient year, increasing with more severe disease. (medscape.com)
  • more than half of all expenditures are attributed to the 10-20% of patients with the most severe disease. (medscape.com)
  • Approximately half of all patients have preexisting allergic conditions such as asthma, allergic rhinitis, drug allergy, and others. (medscape.com)
  • Asthma affects 4% to 5% of the US population, a figure that translates into approximately 13 million patients. (respiratory-therapy.com)
  • The estimated annual per-patient cost for high-cost patients is approximately $2,600, as compared with $140 for the total asthma-patient population. (respiratory-therapy.com)
  • Given the close relationship between the lungs and heart, pulmonologists often work in conjunction with cardiologists, especially when dealing with conditions like pulmonary hypertension. (wikimd.com)