Asthma administration inhalation. Medical search. Frequent questions

The objective of this study was to evaluate and analyse technique of use of the inhalation device used by patients of COPD and Bronchial Asthma. (nih.gov)
Cromolyn sodium inhalation solution USP is a prophylactic agent indicated in the management of patients with bronchial asthma. (nih.gov)
For management of bronchial asthma in adults and pediatric patients (5 years of age and over) who are able to use the Inhaler, the usual starting dosage is two metered inhalations four times daily at regular intervals. (globalrph.com)

Intal Inhaler (cromolyn sodium inhalation aerosol) is a metered dose aerosol unit for oral inhalation containing micronized cromolyn sodium, sorbitan trioleate with dichlorotetrafluoroethane and dichlorodifluoromethane as propellants. (globalrph.com)
Values of skew (an indicator of aerosol distribution homogeneity) obtained from gamma camera lung images after slow and faster inhalation of radiolabeled CS were also compared. (johnshopkins.edu)
Combivent® Inhalation Aerosol is a combination of ipratropium bromide and albuterol sulfate. (theodora.com)
Combivent Inhalation Aerosol contains a microcrystalline suspension of ipratropium bromide and albuterol sulfate in a pressurized metered-dose aerosol unit for oral inhalation administration. (theodora.com)
Combivent Inhalation Aerosol is a combination of the anticholinergic bronchodilator, ipratropium bromide, and the beta 2 -adrenergic bronchodilator, albuterol sulfate. (theodora.com)
Amphastar announced that the Food and Drug Administration (FDA) has approved its New Drug Application (NDA) for Primatene MIST (epinephrine inhalation aerosol bronchodilator suspension) for the temporary relief of mild symptoms of intermittent asthma (eg, wheezing, tightness of chest, shortness of breath) in patients aged ≥12 years. (empr.com)
Among the presentations is a dose-ranging efficacy and safety study in which the treatment was compared to both albuterol hydrofluoroalkane (HFA) Inhalation Aerosol and placebo in pediatric patients (ages 4-11) with asthma. (biospace.com)
The dose of Combivent Inhalation Aerosol is two inhalations four times a day. (rxlist.com)
COMBIVENT Inhalation Aerosol is indicated for use in patients with chronic obstructive pulmonary disease (COPD) on a regular aerosol bronchodilator who continue to have evidence of bronchospasm and who require a second bronchodilator. (rxlist.com)
Safety and efficacy of additional doses of COMBIVENT Inhalation Aerosol beyond 12 puffs/24 hours have not been studied. (rxlist.com)
Also, safety and efficacy of extra doses of ipratropium or albuterol in addition to the recommended doses of Combivent® (ipratropium bromide and albuterol sulfate) Inhalation Aerosol have not been studied. (rxlist.com)
For example, administration of drug by aerosol targets β 2 pulmonary receptors, while limiting systemic drug. (pharmacology2000.com)
A further benefit of aerosol administration is rapid therapeutic response in most cases. (pharmacology2000.com)
QVAR Inhalation Aerosol is not a bronchodilator and is not indicated for relief of acute bronchospasm. (medicalbrandnames.com)

Inhalation powder containing 55 mcg, 113 mcg, or 232 mcg of fluticasone propionate per actuation. (drugs.com)
It is marketed by GlaxoSmithKline under the trade name Relenza as a powder for oral inhalation. (wikipedia.org)
GlaxoSmithKline (GSK) and FDA notified healthcare professionals of a report of the death of a patient with influenza having received zanamivir inhalation powder, which was solubilized and administered by mechanical ventilation. (wikipedia.org)
TEL AVIV, Israel & PARSIPPANY, N.J.--(BUSINESS WIRE)-- Teva Pharmaceuticals USA, Inc., a U.S. affiliate of Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA), today announced that the first findings from the CONNECT clinical program on ProAir ® Digihaler ® (albuterol sulfate) inhalation powder with an integrated electronic module (eModule) will be presented at the European Respiratory Society (ERS) International Congress 2022, held September 4-6 in Barcelona, Spain. (tevausa.com)
ProAir Digihaler (albuterol sulfate) Inhalation Powder is a prescription medicine used in people ≥4 years of age for the treatment or prevention of bronchospasm in people who have reversible obstructive airway disease and for the prevention of exercise-induced bronchospasm. (yahoo.com)
ProAir Digihaler (albuterol sulfate) Inhalation Powder is contraindicated in patients with hypersensitivity to albuterol or patients with a severe hypersensitivity to milk proteins. (yahoo.com)
In what can be hailed as a national achievement, two Sri Lankan scientists, Manoj Hettiarachchi and Nalin Kannangara of Sri Lankan pharmaceutical company Emergen Life Sciences were recently honoured with a Silver Award at the 44th International Exhibition of Inventions held in Geneva for their innovation of a Process of Manufacturing of Budenoside+Foremtrol Dry Powder Inhalation Medicines. (lankabusinessonline.com)
The inhalation device and the powder inhalation mix inside the capsule constitute the drug delivery system. (lankabusinessonline.com)
Commenting on the scientific thinking behind their prize winning innovation, Nalin Kannangara, Chief Scientific Officer of Emergen Life Sciencesand the Co-winner of the coveted Prize, says thatthe unique factor in their research was with regard to the preparation of a novel carrier particle of a suitable particle size in an inhalation powder mix intended for the pulmonary route of administration. (lankabusinessonline.com)
Additional data to be presented include two poster presentations of pediatric data on ProAir RespiClick ® (albuterol sulfate) Inhalation Powder, a breath-actuated, multi-dose, dry-powder, short-acting beta-agonist (SABA) inhaler. (biospace.com)
The company's respiratory pipeline and clinical trial program are based on drug molecules delivered in proprietary dry powder formulations and breath-actuated device technologies, as well as a targeted biologic treatment for severe asthma. (biospace.com)
13 Here the results of inhalation challenge with TMA powder from rats sensitized by dermal TMA exposure are reported. (cdc.gov)

The active ingredient of cromolyn sodium inhalation solution USP is cromolyn sodium, USP. (nih.gov)
Cromolyn sodium inhalation solution USP is clear, colorless to pale yellow, sterile and has a target pH of 5.5. (nih.gov)
Cromolyn sodium inhalation solution is contraindicated in those patients who have shown hypersensitivity to cromolyn sodium. (nih.gov)
Cromolyn sodium inhalation solution has no role in the treatment of status asthmaticus. (nih.gov)
Drug stability and safety of cromolyn sodium inhalation solution when mixed with other drugs in a nebulizer have not been established. (nih.gov)

The ProAir Digihaler System is a digital health system that tracks reliever inhaler usage and inhalation quality as measured by inspiratory flow to aid in clinical decision-making. (tevausa.com)
Teva's Digihaler system is the first and only smart inhaler system that can provide objective inhaler data to help patients and their doctors have informed treatment discussion in support of asthma management. (yahoo.com)
1 QVAR RediHaler is supplied as a breath-actuated inhaler, which eliminates the need for hand-breath coordination during administration. (pharmacytimes.com)
About 68% of patients with asthma do not use their metered dose inhaler (MDI) correctly. (pharmacytimes.com)
Patients with chronic asthma should be advised that the effect of Intal Inhaler therapy is dependent upon its administration at regular intervals, as directed. (globalrph.com)
When a clinical response to Intal Inhaler is evident, usually within two to four weeks, and if the asthma is under good control, an attempt may be made to decrease concomitant medication usage gradually. (globalrph.com)
If concomitant medications are eliminated or required on no more than a prn basis, the frequency of administration of Intal Inhaler may be titrated downward to the lowest level consistent with the desired effect. (globalrph.com)
Primatene MIST is the only approved asthma inhaler available over-the-counter in the US. (empr.com)
Children with asthma often lack the strength to activate their pressurised metered dose inhaler (pMDI). (bvsalud.org)
Background: An Adequate and an effective dose of inhalation drugs can be administered only if the correct inhaler-specific technique is followed by asthma patients. (bvsalud.org)
Aims: This observational study was to assess the inhaler techniques among asthma patients in Nigeria and also to identify the factors related to an inaccurate or poor inhaler use. (bvsalud.org)
of two university hospitals in Nigeria were asked to use their inhalers while an inhaler-administration checklist was used to assess each patients inhaler technique. (bvsalud.org)

Although their exact mechanism is unknown, corticosteroids have demonstrated multiple anti-inflammatory effects in asthma. (pharmacytimes.com)
Corticosteroids inhibit both inflammatory cells and the release of inflammatory mediators, which contribute to their efficacy in asthma. (pharmacytimes.com)
Examples include skin ointments and creams, eye drops, nose sprays, ear drops, vaginal suppositories, as well as drugs injected into joints (e.g. corticosteroids to treat arthritis), the epidural space (e.g. an epidural), or the cerebrospinal fluid (intrathecal administration, e.g. to treat a brain infection with antibiotics). (drugsandpoisons.com)
A reduction in growth velocity in growing children and teenagers may occur as a result of inadequate control of chronic diseases such as asthma or from use of corticosteroids for treatment. (medicalbrandnames.com)
QVAR is also indicated for asthma patients who require systemic corticosteroid administration, where adding QVAR may reduce or eliminate the need for the systemic corticosteroids. (medicalbrandnames.com)
[ 59 ] A controlled prospective study has shown that adjusting inhaled corticosteroid (ICS) treatment to control sputum eosinophilia-as opposed to controlling symptoms, short-acting beta-agonist (SABA) use, nocturnal awakenings, and pulmonary function-significantly reduced both the rate of asthma exacerbations and the cumulative dose of inhaled corticosteroids. (medscape.com)

In 2006 the Food and Drug Administration (FDA) found that breathing problems (bronchospasm), including deaths, were reported in some patients after the initial approval of Relenza. (wikipedia.org)
Occasionally, patients may experience cough and/or bronchospasm following inhalation of cromolyn sodium. (nih.gov)
At times, patients who develop bronchospasm may not be able to continue cromolyn sodium administration despite prior bronchodilator administration. (nih.gov)
For the prevention of acute bronchospasm which follows exercise, exposure to cold, dry air, or environmental agents, the usual dose is two metered inhalations shortly before exposure to the precipitating factor, i.e., within 10 to 15 minutes but not more than 60 minutes. (globalrph.com)

Administration of albuterol can provide rapid relief of bronchospastic symptoms. (pharmacology2000.com)
Short-acting beta-2 agonists (eg, albuterol ) 2 puffs every 4 hours inhaled as needed are the drug of choice for relieving acute bronchoconstriction and preventing exercise-induced asthma. (msdmanuals.com)

each 14.2 g canister delivers at least 200 metered inhalations (100 doses). (globalrph.com)
Ideally, the inhalation route could deliver high doses of antibodies directly to the lungs while limiting system exposure and reducing potential side effects. (genengnews.com)
As of 2013, the beta2-agonists salbutamol, formoterol and salmeterol are allowed by inhalation in therapeutic doses, and no longer require athletes to acquire a therapeutic use exemption. (wada-ama.org)

Maintenance treatment of asthma, in adults not adequately controlled with a maintenance combination of a long-acting beta2-agonist and medium dose of inhaled corticosteroid, and who experienced one or more asthma exacerbations in the previous year. (tga.gov.au)
The first oral presentation will highlight results from an analysis that examined the effect of reslizumab on clinical asthma exacerbations in patients with chronic sinusitis and/or nasal polyps in addition to inadequately controlled asthma and elevated blood eosinophils. (biospace.com)
An improvement in asthma control, a decrease in hospitalizations, and a decrease in exacerbations were noted in those patients in whom sputum-guided therapy was used. (medscape.com)
The value of chest radiography is in revealing complications or alternative causes of wheezing and the minor importance of wheezing in the diagnosis of asthma and its exacerbations. (medscape.com)
Treatment of Acute Asthma Exacerbations The goal of asthma exacerbation treatment is to relieve symptoms and return patients to their best lung function. (msdmanuals.com)

Primary treatment of status asthmaticus or other acute episodes of asthma requiring intensive measures. (drugs.com)
Go to Pediatric Asthma , Status Asthmaticus , Exercise-Induced Asthma , and Asthma in Pregnancy for complete information on these topics. (medscape.com)

Most of these patients had asthma or chronic obstructive pulmonary disease. (wikipedia.org)
Relenza therefore was not recommended for treatment or prophylaxis of seasonal influenza in individuals with asthma or chronic obstructive pulmonary disease. (wikipedia.org)
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are diseases associated with the airflow in the lungs (WHO, 2013). (findaphd.com)
Asthma is a chronic respiratory disease. (globalrph.com)
reports of sleep improvement after melatonin administration in some medical conditions, including patients in intensive care unit[s] with chronic obstructive pulmonary disease and pneumonia," they write. (medscape.com)
For years, the development of drugs for respiratory diseases, mainly asthma and chronic obstructive pulmonary disease (COPD), have relied on the administration of a new drug, mostly by inhalation and assessment by physiologic tests and questionnaires. (sgs.com)
Its combined mechanism of action addresses key issues, making it an ideal choice for individuals suffering from conditions like asthma and chronic obstructive pulmonary disease (COPD). (v-carepharmacy.com)
The significance of this breakthrough is that unlike the imported medications that are costly, the Pate innovated by the Sri Lankan Scientists provides low-cost, easily accessible medications for asthma and its more aggressive form, (Chronic Obstructive Pulmonary Disease) also known as COPD. (lankabusinessonline.com)
Elevated serum IgE levels are required for chronic asthma patients to be treated with omalizumab (Xolair). (medscape.com)
They should not be used alone for long-term maintenance of chronic asthma. (msdmanuals.com)

We investigated the pharmacokinetics of single-dose inhalation of 2 or 4 mg terbutaline, oral ingestion of 10 mg terbutaline, and daily inhalation of 2 mg terbutaline for seven days in urine samples collected 0-24 h after administration in trained male subjects that had performed 90 min of cycling exercise. (wada-ama.org)

Maintenance treatment of asthma as prophylactic therapy in patients 12 years of age and older. (drugs.com)
Starting dosage is based on prior asthma therapy and disease severity. (drugs.com)
The medication is an inhaled corticosteroid indicated as prophylactic therapy for maintenance treatment of asthma in patients aged 4 years and older. (pharmacytimes.com)
If improvement occurs, it will ordinarily occur within the first 4 weeks of administration as manifested by a decrease in the severity of clinical symptoms of asthma, or in the need for concomitant therapy, or both. (globalrph.com)
Respiratory therapists at Mass General participate in the management of hyperbaric oxygen therapy for patients with carbon monoxide inhalation, problem wounds and other ailments and noninvasive positive pressure ventilation is provided for over one thousand patients per year. (massgeneral.org)
Some athletes with asthma or exercise-induced bronchoconstriction (EIB) use combination therapy of both short and long-acting beta2-agonists. (wada-ama.org)
QVAR is indicated in the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older. (medicalbrandnames.com)
In assessing asthma control, the British Thoracic Society recommends using sputum eosinophilia determinations to guide therapy. (medscape.com)
Therefore, all patients with acute asthma should have oxygen saturation measured by pulse oximetry, or they simply should be placed on oxygen therapy. (medscape.com)

A total of 300 cases of BA or COPD patients using different types of inhalation devices were included in this observational study. (nih.gov)
The respiratory disorders with the most significant impact on public health are asthma, COPD, lung cancer and lung infections1. (findaphd.com)
This means that low cost and effective medication is freely available to Sri Lankan consumers, as an alternative to the imported varieties that have been the only solution for Asthma and COPD sufferers in the past. (lankabusinessonline.com)
Commenting on the thinking behind the innovation, Manoj Hettiarachchi, Chairman Emergen Life Sciences said: "We identified a noticeable trend in the increase of Asthma COPD and also understood that the country depended on costlyimported medications for treatment. (lankabusinessonline.com)
Teva Respiratory develops and delivers high-quality treatment options for respiratory conditions, including asthma, COPD and allergic rhinitis. (biospace.com)
Previously, descriptions of pharmacological effects associated with 'non-selective' β-adrenergic receptor agonists used to manage pulmonary diseases such as asthma or COPD necessarily include unwanted side effects often due to β 1 adrenergic receptor activation. (pharmacology2000.com)
Other medications, which are relatively selective for β 2 -adrenergic receptors, retain the benefits in management of asthma and COPD, while limiting adverse effects mediated by β 1 -adrenergic receptor activation. (pharmacology2000.com)

Dosing is limited to the inhalation route. (wikipedia.org)

After inhalation, zanamivir is concentrated in the lungs and oropharynx, where up to 15% of the dose is absorbed and excreted in urine. (wikipedia.org)
After administration by inhalation, approximately 8% of the total cromolyn sodium dose administered is absorbed and rapidly excreted unchanged, approximately equally divided between urine and bile. (nih.gov)
The dose of QVAR RediHaler depends on asthma severity and previous treatment. (pharmacytimes.com)
The investigators explored the effect of exogenous melatonin on sleep quality in 22 consecutive women with mild or moderate asthma (mean age, 29.7 ± 7.7 years) randomized to receive 3 mg of melatonin (n = 12) or placebo (n = 10) in a single dose two hours prior to bedtime for 28 days. (medscape.com)
Following intravenous administration, approximately one-half of the dose is excreted unchanged in the urine. (theodora.com)
Using whole body plethysmography and enhanced pause (Penh) as an index of obstruction, MCb dose-response curves were obtained before the i.t. administration of HM (2.5, 5 and 10 mg per 100 g) or saline, and after (6 - 7.S hr and 30 - 31 hr) treatment. (cdc.gov)
Sereflo should not be used for patients with mild asthma and may not be appropriate for patients with mild to moderate asthma, in whom a low dose of the inhaled corticosteroid, either alone or with a long-acting β 2 agonist, may be required. (medicines.org.uk)
Sereflo could be considered for use in patients with moderate persistent asthma but only where control of symptoms cannot be maintained with a lower strength product containing a lower dose of the corticosteroid. (medicines.org.uk)
Terbutaline accumulated in urine after seven days of daily inhalation compared to single-dose inhalation during the first day, revealing incomplete elimination after 24 h. (wada-ama.org)
Mean maximum urine concentrations of salmeterol unadjusted for specific gravity reached 4.0, 1.6, and 2.0 ng/mL after single-dose inhalation of 400 and 200 µg, and seven consecutive days of inhalation of 200 µg, respectively. (wada-ama.org)
For the commercial LCM drug egg residue experiment, laying hens were divided into low- and high-dose groups (n = 12/group) for each drug and treated with the recommended dosage and administration method for each respective drug. (bvsalud.org)

Two new cases of occupational or allergic asthma were reported. (europa.eu)
Asthma in cats is believed to have an important allergic/inflammatory component1,2. (dvm360.com)
AIM OF THE STUDY: In this study, we analyzed the components of A. decursiva ethanol extract (ADE) by high performance liquid chromatography (HPLC) and investigated the therapeutic effects of ADE against allergic asthma using lipopolysaccharide (LPS) stimulated RAW264.7 cells and an ovalbumin (OVA)-exposed allergic asthma model. (bvsalud.org)
CONCLUSION: This study demonstrated that ADE effectively attenuated allergic inflammation induced by OVA inhalation through the enhancement of Nrf2 expression and suppression of NF-κB expression. (bvsalud.org)
Total serum immunoglobulin E levels greater than 100 IU are frequently observed in patients experiencing allergic reactions, but this finding is not specific for asthma and may be observed in patients with other conditions (eg, allergic bronchopulmonary aspergillosis, Churg-Strauss syndrome). (medscape.com)
Causes or triggers of asthma can be divided into allergic and nonallergic etiologies. (medscape.com)
Co-morbidities of asthma include sinusitis, nasal polyposis, gastro-esophageal reflux disease (GERD) and allergic rhinitis. (medscape.com)
Risk factors for asthma include a family history of allergic disease, the presence of allergen-specific immunoglobulin E (IgE), viral respiratory illnesses , exposure to aeroallergens , cigarette smoke, obesity , and lower socioeconomic status. (medscape.com)
The prevalence of asthma and allergic sensitization was 4 and 6 times lower in the Amish population, with higher median endotoxin levels in house dust. (medscape.com)

Furosemide (Fur) may have an anti-inflammatory effect on airways in patients with asthma although its intrinsic mechanism remains elusive. (ersjournals.com)
It is concluded that furosemide is not effective in protecting against platelet-activating factor challenge in patients with asthma despite its potential inhibition of leukotriene synthesis. (ersjournals.com)
CONNECT1, the first study in the CONNECT clinical program, is a 12-week, open-label, multicenter, randomized, parallel group study that evaluated the ProAir Digihaler System and its impact on asthma management compared to standard of care (SoC) in 333 patients with asthma. (tevausa.com)
The efficacy and safety of QVAR RediHaler were evaluated in 1858 patients with asthma. (pharmacytimes.com)
Failure to deal with sleep problems may lead to impaired disease control and have a great negative impact on quality of life in patients with asthma. (medscape.com)
Objective: We sought to determine the efficacy of slow versus faster inhalation of CS in protecting against allergen challenge in patients with asthma. (johnshopkins.edu)
Methods: Eight patients with asthma underwent two allergen challenges 30 minutes after pretreatment with CS that was inhaled from a large holding chamber at ~30 L/min or ~70 L/min. (johnshopkins.edu)

Cobalt air exposure levels below 0.120 mg cobalt/m³ (in the absence of irritant gases) were not associated with occupational asthma. (europa.eu)
Pilliere et al (1990), Single-case study on occupational exposure to cobalt resinate: Cobalt resinate and cobalt stearate administration precipitated a positive finding in a bronchio-constriction test. (europa.eu)
A cobalt industry-wide questionnaire exercise for cases of occupational asthma following cobalt exposure was conducted in 2010. (europa.eu)
The questionnaire indicates that there is some cobalt industry experience with occupational asthma in addition to the occupational exposure studies reported in the literature. (europa.eu)
Cobalt exposure has been reported to induce immune responses in some hardmetal workers diagnosed with occupational asthma or reduced lung function (as indicated by measured IgE titres). (europa.eu)
Methods Of 5600 HCPs surveyed, 3650 responded to a validated questionnaire about their occupation, asthma diagnosis, variability of asthma symptoms at and away from work, and exposure to individual cleaning substances. (bmj.com)
Quaternary ammonium compounds can cause toxic effects by all routes of exposure including inhalation, ingestion, dermal application and irrigation of body cavities. (inchem.org)
Since exposure was to the tetryl-laden dusts, the effects could have been caused by inhalation, direct skin contact, or by swallowing. (cdc.gov)
therefore, in this profile, it is assumed that the primary route of exposure was inhalation. (cdc.gov)
No studies were available regarding cardiovascular, musculoskeletal, renal, dermal or ocular effects in humans after inhalation exposure to tetryl. (cdc.gov)
No studies were located regarding systemic effects in animals after inhalation exposure to tetryl. (cdc.gov)
Furthermore, the egg residue profiles confirmed reduced systemic drug exposure after oral administration. (bvsalud.org)
[ 7 ] Using a cross-sectional design, the authors compared children living on farms to those in a reference group with respect to the prevalence of asthma and to the diversity of microbial exposure. (medscape.com)

In Dry Power Inhalation treatment known as DPI, the active ingredient is routed through the respiratory pathway to the site of action i.e the lungs to exert the desired therapeutic effect. (lankabusinessonline.com)

The bronchodilation following inhalation of ipratropium bromide is primarily a local, site-specific effect, not a systemic one. (theodora.com)
Following inhalation, bronchodilation may be apparent within 15 min. (pharmacology2000.com)

ARMONAIR RESPICLICK should be administered as 1 inhalation twice daily (approximately 12 hours apart) by the orally inhaled route. (drugs.com)
The pulmonary route hasn't worked so well for omalizumab, a mAb that is approved for subcutaneous administration in the treatment of asthma. (genengnews.com)
Therefore the preferred route of administration of NS is by inhalation, and in those with greater degrees of airways inflammation, NS may exert some effect by delivery to sites of action via the bronchial circulation. (soton.ac.uk)
Route of administration: Inhalation use. (medicines.org.uk)

Short-acting β 2 -adrenergic agonists administered by inhalation represent drugs of choice for management of acute asthma presentations and for prevention of exercise-induced bronchospastic reactions. (pharmacology2000.com)
Arterial blood gas (ABG) measurement provides important information in acute asthma. (medscape.com)
The clinical picture usually obviates ABGs for most ED patients with acute asthma. (medscape.com)
Pulse oximetry measurement is desirable in all patients with acute asthma to exclude hypoxemia. (medscape.com)
The hypoxemia of uncomplicated acute asthma is readily reversible by oxygen administration. (medscape.com)
In children, pulse oximetry is often used to grade severity of acute asthma. (medscape.com)

The incorporation of fluticasone propionate empowers the medication to efficiently manage airway inflammation, leading to a reduction in the severity of asthma symptoms and overall improvement in lung health. (v-carepharmacy.com)

AstraZeneca agreed to pay Pieris $45 million upfront and $12.5 million tied to initiating a Phase I trial of Pieris' lead preclinical candidate, PRS-060, an interleukin-4 receptor alpha agonist designed to treat moderate to severe asthma. (genengnews.com)
Teva will present results from several analyses of data from the pivotal Phase III clinical trial program for reslizumab, an investigational humanized anti-interleukin-5 (IL-5) monoclonal antibody (mAb) for add-on maintenance treatment of severe asthma with an eosinophilic phenotype. (biospace.com)
Oxygen saturation of 97% or above constitutes mild asthma, 92-97% constitutes moderate asthma, and less than 92% signifies severe asthma. (medscape.com)
They are used for moderate and severe asthma but should never be used as monotherapy. (msdmanuals.com)
Ultra-long-acting beta agonists (eg, indacaterol ) are active for up to 24 hours and as with long-acting beta agonists are used for moderate to severe asthma, and should never be used as a monotherapy. (msdmanuals.com)

M]elatonin as used in this study can improve subjective sleep quality in patients with mild and moderate asthma in the absence of any significant change in pulmonary function," the authors conclude, suggesting that the long-term effects of melatonin on airway inflammation and bronchial hyperresponsiveness be evaluated prior to its use in the management of sleep disturbances in asthmatics. (medscape.com)
Airway hyper-responsiveness is probably related to airway inflammation, a suggestion supporting use of inhaled steroids as part of asthma management in many cases. (pharmacology2000.com)
In the asthma model, the administration of ADE reduced inflammatory cell count and airway hyperresponsiveness in OVA-exposed animals with decreased levels of IL-4, IL-13, and OVA-specific immunoglobulin E. These results were accompanied by the reduction of pulmonary inflammation and mucus secretion. (bvsalud.org)
Asthma Asthma is a disease of diffuse airway inflammation caused by a variety of triggering stimuli resulting in partially or completely reversible bronchoconstriction. (msdmanuals.com)
Asthma is a clinical syndrome characterized by episodic reversible airway obstruction, increased bronchial reactivity, and airway inflammation. (medscape.com)

Symptoms of asthma may recur if cromolyn sodium is reduced below the recommended dosage or discontinued. (nih.gov)

is a commonly used selective β 2 -adrenergic receptor agonist that may be administered either orally or by inhalation. (pharmacology2000.com)

Background: Approximately one third of patients with allergy-induced asthma who are treated with aerosolized cromolyn sodium (CS) fail to achieve a full therapeutic effect. (johnshopkins.edu)
We investigated urine concentrations of salmeterol 0-24 h after therapeutic (200 µg) and supratherapeutic (400 µg) inhalation, as well as after seven days of daily therapeutic inhalation (200 µg/d) in endurance athletes who performed cycling exercise to mimic real-life doping control settings. (wada-ama.org)
Therefore, ADE may be a potential therapeutic agent for controlling asthma. (bvsalud.org)

The CONNECT1 trial was conducted to assess the role of the ProAir Digihaler System in the treatment of asthma. (tevausa.com)
One poster presentation will explore the effectiveness of the ProAir Digihaler System on improving asthma control versus SoC in adult and pediatric (13 years of age and older) patients with suboptimal asthma control. (tevausa.com)
A second poster presentation will examine the impact of the ProAir Digihaler System on patient-physician interactions as part of asthma management versus SoC. (tevausa.com)
We are excited to showcase these data to provide important insights into the use of a digital tool and how data collected from the ProAir Digihaler System may help inform more personalized asthma management," said Randall Brown, MD, Global Lead, Digital Health, Immunology and Respiratory Medical Affairs at Teva. (tevausa.com)
ProAir Digihaler alone may not be adequate to control asthma in many patients. (yahoo.com)
The AAAAI Annual Meeting provides Teva with an exciting opportunity to showcase the important work being done to support our goal of bringing additional options, such as reslizumab and ProAir RespiClick ® , to asthma patients," said Tushar Shah, MD, Senior Vice President, Teva Global Respiratory Research and Development. (biospace.com)

Deterioration of asthma and acute episodes: Do not use for relief of acute symptoms. (drugs.com)

Anaphylactic reactions with cromolyn sodium administration have been reported rarely. (nih.gov)
One study, which investigated skin and anaphylactic reactions of guinea pigs sensitized by inhalation of tetryl smoke (Gel1 1944), is discussed below. (cdc.gov)

Other services include asthma education, bronchoscopy assistance, and aerosolized antibiotic administration. (massgeneral.org)

Each 2 mL vial for oral inhalation use only contains 20 mg cromolyn sodium, USP in water for injection, USP. (nih.gov)
For patients 4 to 11 years, it should be given as 40 or 80 mcg by oral inhalation twice daily. (pharmacytimes.com)
For patients 12 years and older, it should be given as 40, 80, 160, or 320 mcg by oral inhalation twice daily. (pharmacytimes.com)
The second oral session will present results from a pooled analysis that evaluated the efficacy of reslizumab in patients aged 65 years and older with asthma and elevated blood eosinophils. (biospace.com)
Urine concentrations of terbutaline were higher after inhalation of 4 mg than after oral ingestion of 10 mg during the first 4 h after administration, whereas concentrations of terbutaline were lower after inhalation of 4 mg than after oral ingestion of 10 mg 12 h after administration. (wada-ama.org)
It is concluded that inhalation of 2-4 mg terbutaline cannot be discriminated from 10 mg oral ingestion on the basis of urine concentrations for doping control purposes. (wada-ama.org)
In this study, we aimed to investigate the oral bioavailability of LCM with PK data after IV and PO administration and to compare differences in drug residue patterns in eggs. (bvsalud.org)

Although the pathophysiology of feline asthma is not completely understood, it is presumed to originate as a type I hypersensitivity reaction. (dvm360.com)
Although it has been suggested that dietary hypersensitivity may be related to feline asthma, there is no scientific evidence supporting such point. (dvm360.com)

Treatment of asthma in patients 12 years and older: 1 inhalation of ARMONAIR RESPICLICK 55 mcg, 113 mcg, or 232 mcg twice daily. (drugs.com)

The major signs of feline asthma include recurrent episodes of cough and dyspnea resulting from bronchoconstriction. (dvm360.com)
ETHNOPHARMACOLOGICAL RELEVANCE: Angelica decursiva Franchet & Savatier is a traditional medicinal plant used to treat asthma, cough, headache, pyrexia and thick phlegm in China, Japan and Korea. (bvsalud.org)
In genetically susceptible individuals, these interactions can lead the patient with asthma to symptoms of breathlessness, wheezing, cough, and chest tightness. (medscape.com)

Improved subjective sleep quality associated with melatonin administration could not be correlated to any improvement in lung function or in asthma symptoms," the authors point out. (medscape.com)
1. Lung function was studied in fifty-six symptom-free asthmatic subjects after the inhalation of urea, an agent not previously used for asthma provocation. (portlandpress.com)

In asthma management, poor handling of inhalation devices and wrong inhalation technique are associated with decreased medication delivery and poor disease control. (nih.gov)
as a result, a considerable amount of state funds are spent on the procurement of Asthma medication which costs the nation precious foreign exchange" he reiterated. (lankabusinessonline.com)
Evaluating whether the inhalation technique is being performed correctly to ensure that the medication is being delivered effectively. (smartdev.com)

Pressurised inhalation, suspension. (medicines.org.uk)

In Northern Europe, terbutaline is a commonly prescribed beta2-adrenoceptor agonist in treatment of asthma and exercise induced bronchoconstriction. (wada-ama.org)
Salmeterol is another beta2-agonist widely used in treatment of asthma and exercise-induced bronchoconstriction among athletes. (wada-ama.org)

Prolonged BDP treatment reduces inflammatory infiltration, proinflammatory cytokine expression, and subepithelial collagen deposition, a recognized abnormality in asthma. (nih.gov)
For example, lower molecular weight and more potent forms of antibodies are being evaluated for topical delivery, including an anti-interleukin-13 Fab for the treatment of asthma and a highly potent nanobody to treat infection with the respiratory syncytial virus. (genengnews.com)
Nedocromil sodium (NS) is a small hydrophilic molecule active in the treatment of asthma. (soton.ac.uk)

Small particles and the drug deposition of QVAR can make a big difference in improving asthma control for your patients. (medicalbrandnames.com)

JERUSALEM--( BUSINESS WIRE )--Teva Pharmaceutical Industries Ltd., (NYSE and TASE: TEVA) today announced that five company-sponsored abstracts will be presented at the 2016 Academy of Allergy, Asthma and Immunology (AAAAI) Annual Meeting in Los Angeles, California on March 4-7, 2016. (biospace.com)

Patients with higher educational qualification (P 0.01) and those with less frequent asthma symptoms (P 0.01) are more likely to use the pMDI inhalers more accurately while patients who have been taught previously by a Doctor were more likely to use the DPI better. (bvsalud.org)
Conclusion: Majority of asthma patients use their inhalers inaccurately. (bvsalud.org)

Eleven patients were studied (mean+/-sem 22+/-0.8 yrs) with mild asthma (forced expiratory volume in one second, 95+/-4%) in a randomized, double-blind, placebo-controlled, cross-over fashion, one week apart. (ersjournals.com)
3. Mild hypoxaemia, ventilation-blood-flow inequality and impairment of gas transfer also occurred after urea administration. (portlandpress.com)

Feline asthma consists of an inflammatory disorder of the lower respiratory system of cats that results in bronchoconstriction and limited airflow to the lungs. (dvm360.com)

Support cores (Administration, Data Management & Analysis, Community Engagement, Research Experience and Training Coordination, Materials, and Inhalation Toxicology) will provide essential, centralized reagents/services and technological resources allowing for precision of data and economy of effort, and foster interdisciplinary activities. (hhs.gov)

The chest radiograph remains the initial imaging evaluation in most individuals with symptoms of asthma. (medscape.com)

MATERIALS AND METHODS: To establish asthma model, the mice were sensitized on day 0 and 14 via intraperitoneal injection of OVA with aluminum hydroxide. (bvsalud.org)

Asthma results from complex interactions among inflammatory cells, their mediators, airway epithelium and smooth muscle, and the nervous system. (medscape.com)

It is an inhaled anti-inflammatory agent for the preventive management of asthma. (nih.gov)
Disturbed sleep and its daytime consequences are relevant problems in the management of asthma," write Francineide L. Campos, MPharm, and colleagues, from the Universidade Federal do Ceará in Fortaleza, Brazil. (medscape.com)

The half-life of elimination is about 2 hours after inhalation or intravenous administration. (theodora.com)

Anatomy18

Organisms14

Diseases35

Chemicals and Drugs73

Analytical, Diagnostic and Therapeutic Techniques and Equipment77

Psychiatry and Psychology2

Phenomena and Processes36

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena3

Humanities1

Information Science2

Named Groups1

Health Care35

Geographicals1

Bronchial Asthma3

Aerosol14

Powder12

Cromolyn sodium inhalation5

Inhaler12

Corticosteroids6

Bronchospasm4

Albuterol2

Doses3

Exacerbations5

Status asthmaticus2

Chronic10

Pharmacokinetics1

Therapy9

COPD7

Dosing1

Dose11

Allergic9

Patients with asthma7

Exposure13

Active ingredient1

Bronchodilation2

Route4

Acute asthma6

Fluticasone1

Severe asthma5

Inflammation5

Dosage1

Orally1

Therapeutic3

ProAir6

Deterioration1

Anaphylactic2

Bronchoscopy1

Oral7

Hypersensitivity2

RESPICLICK1

Cough3

Lung2

Medication3

Suspension1

Exercise induced2

Treatment3

Improving asthma control1

Pharmaceutical1

Inhalers2

Mild2

Bronchoconstriction1

Coordination1

Symptoms of asthma1

Injection1

Airway1

Management of asthma2

Intravenous administration1