Association between synovitis. Medical search. Frequent questions

Synovitis is more commonly found in rheumatoid arthritis than in other forms of arthritis, and can thus serve as a distinguishing factor, although it is also present in many joints affected with osteoarthritis. (wikipedia.org)
Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy. (ox.ac.uk)
Significant associations were found between the number of regions affected by synovitis and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain, effusion, and joint line tenderness. (ox.ac.uk)
MacKay J, Watkins L, Gold G, Kogan F. [ 18 F]NaF PET-MRI provides direct in-vivo evidence of the association between osseous metabolic activity and adjacent synovitis in knee osteoarthritis: a cross-sectional study. (stanford.edu)
Approximately 1.5% of patients with transient synovitis develop LCP, Coxa magna, osteoarthritis, or recurrences. (medscape.com)
Our aim was to investigate associations between ultrasonographic and magnetic resonance imaging (MRI) inflammatory features, radiographic osteophytes, and thumb base pain in hand osteoarthritis patients. (uludag.edu.tr)
Using binary regression analysis model for pain, taking VAS 4 as a cut off to indicate significant pain, we found that the main cause of pain was CTS, followed by osteoarthritis and then synovitis. (sohag-univ.edu.eg)
Conclusion: Osteoarthritis, CTS, synovitis are the main MSK disorders of type 2 DM. (sohag-univ.edu.eg)

Magnetic resonance imaging was performed on all the PsA and PsO patients looking for synovitis, tenosynovitis, osteitis, periarticular inflammation, bone erosions, and bone proliferations. (medpagetoday.com)
Imaging findings in patients with a combination of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) are often misinterpreted as discitis/osteomyelitis or metastases, resulting in multiple biopsies and delayed diagnosis. (ajnr.org)
SAPHO was proposed to refer to a combination of synovitis, acne, pustulosis, hyperostosis, and osteitis as a heading for these syndromes. (ajnr.org)
Moreover, different extra-articular manifestations, such as uveitis inflammatory bowel disease, celiac disease, Synovitis Acne Pustulosis Hyperostosis Osteitis (SAPHO) syndrome or less common cardiac and/or pulmonary involvement may encompass jSPA spectrum. (frontiersin.org)
Syndrome of synovitis acne pustulosis hyperostosis osteitis (SAPHO) and chronic recurrent multifocal osteomyelitis (CRMO) present two diseases of a dermatologic and rheumatologic spectrum that are variable in manifestation und therapeutic response. (biomedcentral.com)
Therefore, we aimed to clinically characterize a patient group with syndrome of synovitis acne pustulosis hyperostosis osteitis (SAPHO) ( n = 47) and chronic recurrent multifocal osteomyelitis (CRMO)/ chronic non-bacterial osteomyelitis (CNO) ( n = 9) and analyze a CRMO candidate gene. (biomedcentral.com)
In these reports osteitis was a predominant finding and synovitis seemed to be of less importance. (openrheumatologyjournal.com)

US muscloskeletal evaluation was done to evaluate synovitis, tenosynovitis paratenonitis, erosions, trigger finger by B mode and PD. (sohag-univ.edu.eg)

In rheumatoid arthritis, the fibroblast-like synoviocytes, highly specialized mesenchymal cells found in the synovial membrane, play an active and prominent role in the synovitis. (wikipedia.org)
Rice bodies were originally described in association with tuberculous arthritis but are now most frequently seen in patients with rheumatoid arthritis 1 although any inflammatory arthropathy may predispose a patient to this complication. (scielo.org.za)
Researchers evaluated grey scale ultrasound and power Doppler ultrasound synovitis to predict joint damage progression in rheumatoid arthritis. (rheumatologyadvisor.com)
Synovitis in grey scale ultrasound (GSUS) predicts joint damage progression in patients with rheumatoid arthritis (RA), according to study results published in Rheumatology . (rheumatologyadvisor.com)
Synovitis in rheumatoid arthritis detected by grey scale ultrasound predicts the development of erosions over the next three years [published online October 19, 2019]. (rheumatologyadvisor.com)
This finding implies that synovitis may be of minor importance, especially in comparison to other inflammatory joint diseases such as rheumatoid arthritis. (openrheumatologyjournal.com)
Association of Killer Cell Immunoglobulin- Like Receptor Genes in Iranian Patients with Rheumatoid Arthritis. (cdc.gov)

We present the clinical and ultrasound findings of four patients with moderate synovitis and urticarial skin lesions associated with sports activity in warm environments. (reumatologiaclinica.org)
Data of 259, 287, and 250 patients were included for the power Doppler ultrasound synovitis (PDUS), GSUS, and combined composite score (CombUS), respectively. (rheumatologyadvisor.com)

Transient synovitis (TS) is the most common cause of acute hip pain in children aged 3-10 years. (medscape.com)
However, excluding infections and trauma, transient synovitis is one of the most common causes of joint pain in the pediatric age group. (medscape.com)
The possible etiologic relationship between transient synovitis and Legg-Calvé-Perthes disease (LCP) is controversial. (medscape.com)
Although some children with transient synovitis may develop LCP, whether persistence of increased intraarticular pressure eventually causes avascular necrosis or whether patients may have a synovitis that occurs before detection of femoral head collapse is not fully known. (medscape.com)
Transient synovitis affects boys twice as often as girls. (medscape.com)
[ 1 ] however, transient synovitis has been reported in a 3-month-old infant and in adults. (medscape.com)
Nonetheless, children outside the typical age group are unlikely to have transient synovitis. (medscape.com)
Transient synovitis of the hip: more evidence for a viral aetiology. (medscape.com)
Saulsbury, Frank T. MD. Lyme Arthritis presenting as Transient Synovitis of the Hip. (medscape.com)
Topoz I, Manole MD. Limping in toddlers: pelvic abscess presenting with transient synovitis picture. (medscape.com)
Del Beccaro MA, Champoux AN, Bockers T, Mendelman PM. Septic arthritis versus transient synovitis of the hip: the value of screening laboratory tests. (medscape.com)
Validation of a clinical prediction rule for the differentiation between septic arthritis and transient synovitis of the hip in children. (medscape.com)
Yagupsky P, Dubnov-Raz G, Gené A, Ephros M. Differentiating Kingella kingae Septic Arthritis of the Hip from Transient Synovitis in Young Children. (medscape.com)
Information and guidance on transient synovitis (irritation of the hip joint) in children. (pediatricgroupqc.com)

In this cross-sectional substudy, associations between validated MRI-based semiquantitative synovial scores of the knee and the following markers of inflammation were investigated: self-reported pain and stiffness, effusion, warmth, joint line tenderness, erythrocyte sedimentation rate, radiographic severity, and functional ability tests. (ox.ac.uk)
CONCLUSION: There is a strong positive association between synovitis and self-reported patient pain and clinically detectable effusion. (ox.ac.uk)

Synovitis symptoms can be treated with anti-inflammatory drugs such as NSAIDs. (wikipedia.org)
The association of bone disease and chronic cutaneous pustular lesions has been observed since the 1960s, but it was not until 1987 that Chamot et al 1 first used the acronym SAPHO to describe this rare group of chronic, relapsing, inflammatory osteoarticular disorders commonly associated with skin manifestations. (ajnr.org)
The aim of this study was to investigate the relationship between arthroscopy synovitis grade in patients with unilateral high condylar fractures and concentrations of the pro-inflammatory cytokines tumour necrosis factor (TNF)-alpha as well as of matrix metalloproteinases (MMPs) in washed-out synovial fluid (SF) samples obtained from those patients. (elsevierpure.com)
The main findings of this particular JIA subtype are axial and/or peripheral arthritis, inflammatory back pain, enthesitis and a specific association with the HLA-B27 typing. (frontiersin.org)
Systemic-onset juvenile idiopathic arthritis (sJIA) is a type of auto-inflammatory disease that shows clinical manifestations such as fever, rash, hepatosplenomegaly, serositis, and synovitis ( 1 1. (scielo.br)
Psoriatic arthritis (PsA) is a chronic inflammatory arthropathy characterized by the association of arthritis and psoriasis. (biomedcentral.com)
A three-way interplay of DR4, autoantibodies and synovitis in biopsy-proven idiopathic inflammatory myositis. (cdc.gov)

Synovitis is the medical term for inflammation of the synovial membrane. (wikipedia.org)

SAPHO syndrome is an association of specific bone, joint, and skin lesions. (archintsurg.org)

Conclusion: A score based on SJC28 and CRP alone demonstrated stronger associations with synovitis and radiographic progression than the original DAS28 and should be considered in research on pathophysiological manifestations of early RA. (whiterose.ac.uk)
There was a significant association of radiographic progression for PDUS scores beyond the upper limit of normal (1/54), and for the GSUS and CombUS scores at their 50th percentiles (9/54 and 10/54, respectively) and their 75th percentiles (14/54 and 15/54, respectively). (rheumatologyadvisor.com)

Pigmented villonodular synovitis (PVNS), also known as diffuse tenosynovial giant cell tumor, is a benign proliferative disorder of uncertain etiology that affects synovial lined joints, bursae, and tendon sheaths (see the images below). (medscape.com)
Abstract Background: Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare, but well-deﬁned syndrome com- prising polyarthritis with symmetrical synovitis of the small joints in hands and feet accompanied by marked pitting edema. (razavihospital.ir)
Presence of synovitis was retrospectively evaluated in 157 joints. (bvsalud.org)

The diagnosis of synovitis with rice body formation was confirmed at arthroscopy. (scielo.org.za)

In the subset of patients who had MRI, the highest category of WBC count was associated with greater observed synovitis, cartilage loss, and bone marrow lesions, as well as a trend toward greater within-person improvement of synovitis after injection. (medscape.com)

A rheumatologist will aim to diagnose the cause of the patient's pain by first determining whether it is inside the joint itself, meaning true synovitis, or if it is actually caused by an inflammation of the tendons, referred to as tendonitis. (wikipedia.org)

MCP IV synovitis, but not PIP involvement or finger joint tenderness, also has a substantial impact on grip force. (lu.se)
When we examine ACE genotype frequencies according to the clinical characteristics there was a statistically significant association between DD genotype and ocular involvement (p=0.04) also sacroiliac joint involvement (p=0.03). (molvis.org)

Synovitis causes joint tenderness or pain, swelling and hard lumps, called nodules. (wikipedia.org)
In generalized estimating equations, the impact of time-varying synovitis/tenderness on grip force over time was estimated. (lu.se)

SF samples were collected before performing arthroscopy to determine synovitis grade. (elsevierpure.com)

Synovitis may occur in association with arthritis as well as lupus, gout, and other conditions. (wikipedia.org)
Some teenagers with enthesitis-associated arthritis are initially diagnosed erroneously with toxic synovitis when they first present with hip pain. (medscape.com)
International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. (scielo.br)
Association of the CCR5 gene with juvenile idiopathic arthritis. (cdc.gov)

Conclusion: MCP I synovitis is the major contributor to reduced grip force in patients with early RA. (lu.se)
High levels were found in both seropositive and seronegative (as judged by latex slide and sheep cell differential agglutination for IgM antiglobulins) patients with RA and were associated with systemic disease but not synovitis. (bmj.com)
The important differential diagnoses that need to be excluded in patients with rice bodies are synovial chondromatosis and pigmented villonodular synovitis. (scielo.org.za)
Furthermore, the concentrations of TNF-alpha and MMP-3 were significantly higher as compared to the control group, comprised of TMJs on the non-fracture side of the same patients, while a correlation was also noted between TNF-alpha concentration and synovitis grade in the fracture group. (elsevierpure.com)
While the criteria of International League of Associations for Rheumatology (ILAR) are most commonly used by pediatric rheumatologists to classify this entity in children, ERA patients are often regarded as having an undifferentiated form of juvenile spondyloarthritis (jSpA) ( 1 , 8 ). (frontiersin.org)
Synovitis was the third most important MSK finding among DM patients, with a synovitis score of 60.97±11.67 among DM cases and 36.80±7.70 among controls. (sohag-univ.edu.eg)

Injection of beta-emitting radioisotopes to locally treat synovitis has been performed in people for decades and is now being applied using tin-117m in veterinary medicine to treat canine elbow synovitis. (wikipedia.org)

The present study was aimed to know the association of abdominal symptoms and GSD. (archintsurg.org)
Logistic regression was used for univariate and multivariate analysis to find out different symptoms and analyze the independent association of these symptoms with GSD. (archintsurg.org)

The detection rates and concentrations of TNF-alpha and MMPs were determined, and their association with synovitis grade was analysed. (elsevierpure.com)

OBJECTIVES: To assess prevalence of cartilage injury in the equine metacarpo-/metatarsophalangeal joint and its association to fragment size, location, age and lameness. (bvsalud.org)
Linear regression analysis was used to assess strength of association between age and mean cartilage score. (bvsalud.org)
There was a significant association between age and mean cartilage score (b = 0.18, 95% CI = 0.14-0.22, p (bvsalud.org)

Background: Previous studies demonstrated that significant association was found between IL-34 synovial tissue expression and synovitis severity in RA. (iomcworld.org)
Before injection, the authors found no significant associations between synovial fluid WBC categories and age, pain, or OA disease severity. (medscape.com)

Associations of combined US grey scale and power Doppler scores (GSPD) with 28 tender joint count and 28 swollen joint count (SJC28), CRP, ESR and general health visual analogue scale were examined in linear mixed model regressions. (whiterose.ac.uk)

The longer duration of DM was associated with higher prevalence of all MSK manifestations, and this association was more prevalent than the association between the MSK manifestations and the disease control. (sohag-univ.edu.eg)

Linear regression models adjusted for age, body mass index (BMI), and anti-TNF intake were conducted to evaluate the association between the presence of Achilles enthesitis at baseline and the patient-reported outcome (PRO) scores at baseline. (biomedcentral.com)
It was verified that there is an association between the presence and absence of injury with the variable height and variable time. (bvsalud.org)

Long term occurrence of synovitis can result in degeneration of the joint. (wikipedia.org)

Each additional region affected by synovitis was associated with an increase in WOMAC pain (1.82 [95% confidence interval (95% CI) 0.05, 3.58], P = 0.04), and the association with extent of medial synovitis was particularly strong (3.21 [95% CI 0.43, 5.99], P = 0.02). (ox.ac.uk)

Association with cognition and metabolism in adult childhood-onset survivors. (lu.se)

Synovitis of MCP I and MCP IV (12% at baseline) was significantly associated with reduced grip force over time in both hands. (lu.se)
Also to estimate any association between their baseline serum levels and disease activity, subsequent joint destruction and osteoporosis. (iomcworld.org)

Synovitis score for each patient was calculated by simple summation of the MSUS scores for each individual joint, taking a score from 0-3 on gray zone. (sohag-univ.edu.eg)
As each patient had 15 joint in each hand, and every joint was examined in palmar and dorsal views, this means that the synovitis score would take a value from 0-180. (sohag-univ.edu.eg)

Specific treatment depends on the underlying cause of the synovitis. (wikipedia.org)

Very high levels (more than twice the upper limit of normal) showed a strong association with vasculitis. (bmj.com)

2 Recently, over 5 years, we have had the experience of observing and treating 4 cases of local synovitis associated with weals after isolated physical effort at high temperatures. (reumatologiaclinica.org)

According to the American Association for Surgery of the Hand, the swollen tissue can stretch the surrounding ligaments, leading to deformity and instability. (dailyplanetpost.com)

This study was supported by the Swedish Research Council, The Swedish Rheumatism Association, Region Skåne, and Lund University. (lu.se)

The association between human endogenous retroviruses and multiple sclerosis: A systematic review and meta-analysis. (nottingham.ac.uk)
Additionally, to our knowledge immunohisto-chemical analysis of spinal synovitis except for sakroiliitis has not been undertaken so far. (openrheumatologyjournal.com)

Anatomy16

Diseases19

Chemicals and Drugs4

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Psychiatry and Psychology1

Phenomena and Processes1

Osteoarthritis8

Osteitis7

Tenosynovitis1

Rheumatoid arthritis7

Ultrasound2

Transient14

Effusion2

Inflammatory7

Synovial membrane1

SAPHO1

Radiographic progression2

Joints3

Diagnosis1

Bone marrow1

Inflammation1

Involvement2

Tenderness2

Arthroscopy1

Arthritis4

Patients6

Elbow1

Symptoms2

Detection1

Cartilage3

Severity2

Doppler1

Manifestations1

Presence2

Occurrence1

Extent1

Metabolism1

Baseline2

Patient2

Treatment1

Levels1

High1

Hand1

Study1

Analysis2