Association between hyperuricemia. Medical search. Frequent questions

The prevalence rates of hyperuricemia (defined as serum uric acid >7.0/6.0 mg/dL in men / women ) were 29.8% and 13.6%, respectively (p (bvsalud.org)
The prevalence of hyperuricemia increases with age in all populations and especially in women after menopause. (medicalxpress.com)
Study results suggest that weekend catch-up sleep is linked with a lower prevalence of hyperuricemia in postmenopausal women with insufficient sleep. (medicalxpress.com)
This study shows that weekend catch-up sleep of just 1 to 2 hours was linked with a lower prevalence of hyperuricemia in postmenopausal women with insufficient sleep. (medicalxpress.com)
We sought to determine the prevalence and factors associated with hyperuricemia in non-dialysed CKD adult patients in Cameroon. (biomedcentral.com)
Although hyperuricemia is a recognised feature of CKD, studies evaluating its prevalence in CKD are relatively sparse in SSA. (biomedcentral.com)
We therefore sought to determine the prevalence and factors associated with hyperuricemia in non-dialysed adult CKD patients in Cameroon, in order to generate findings that would help determine interventions to reduce CKD mortality, particularly in resources limited countries. (biomedcentral.com)
The aim was to determine the prevalence and pattern of hyperuricemia in predialysis CKD patients attending a teaching hospital in Southern Nigeria. (smjonline.org)
The prevalence of hyperuricemia in the CKD subjects was 47.5% and this was significantly higher than 15% observed in the control group ( P ≤ 0.001). (smjonline.org)
The prevalence of hyperuricemia was highest in CKD stage 3b. (smjonline.org)
Prevalence of hyperuricaemia in an Eastern Chinese population:a cross-sectional study [J]. BMJ Open, 2020, 10(5):e035614. (magtech.com.cn)

Hyperuricemia: Bempedoic acid may increase blood uric acid levels. (globenewswire.com)
Gout is primarily associated with high Uric Acid levels in blood (Hyperuricemia) that causes joints pain or arthritic symptoms. (ayurvedic-herbalist.com)
High Uric Acid levels in blood or Hyperuricemia is the universal factor present in Gout. (ayurvedic-herbalist.com)
CSA-OA treated rats had higher uric acid levels in association with more severe arteriolar hyalinosis and tubulointerstitial damage. (ewha.ac.kr)

When high blood uric acid is present without causing any symptoms, it is simply called Silent or Asymptomatic Hyperuricemia . (ayurvedic-herbalist.com)

The available pathophysiologic evidence points toward inflammation, the characteristic difference between gout and hyperuricemia, as the likely pathway. (natap.org)

In the analysis of the effect of hyperuricemia on left atrial size, high UA levels were significantly associated with inflammation, insulin resistance, and increased left atrial size. (medpagetoday.com)
The effect of hyperuricemia on CSA nephropathy was determined by blocking the hepatic enzyme uricase with oxonic acid (CSA-OA). (ewha.ac.kr)

Previous studies have reported that sleep duration may increase the risk of hypertension and hyperuricemia. (ndhu.edu.tw)
We investigated whether sleep duration was independently associated with hypertension and hyperuricemia. (ndhu.edu.tw)
We aimed to assess the association between sleep duration, hypertension, and hyperuricemia in a population-based cross-sectional study. (ndhu.edu.tw)
There were excellent response rates to sleep duration associated with hypertension and hyperuricemia questions and measurements representative sample of Taiwan population. (ndhu.edu.tw)

The independent risk relationship between hyperuricemia and acute MI is confirmed. (natap.org)

In a study of over 2500 people resident in Taiwan, a blood lead level exceeding 7.5 microg/dL (a small elevation) had odds ratios of 1.92 (95% CI: 1.18-3.10) for renal dysfunction and 2.72 (95% CI: 1.64-4.52) for hyperuricemia. (wikipedia.org)
To determine if hyperuricemia and gouty arthritis are independent risk factors for acute myocardial infarction (MI) and, if so, whether they are independent of renal function, diuretic use, metabolic syndrome, and other established risk factors. (natap.org)
URAT1, a molecular therapeutic target for gout/hyperuricemia, was initially derived from research into hereditary renal hypouricemia (RHUC). (researchgate.net)
Hyperuricemia in CKD has been mostly attributed to declining renal function [ 28 ]. (biomedcentral.com)
The aim of this study was to evaluate the association between preoperative serum UA levels and post-donation long-term events and renal function. (researchsquare.com)
25) Other studies from Korea and Turkey suggested that preoperative hyperuricemia predicted impaired postoperative renal functions at 6 and 12 months in living donors. (researchsquare.com)
26-28) We have also reported that preoperative hyperuricemia was strongly associated with suboptimal renal compensatory hypertrophy at 12 months after renal donation. (researchsquare.com)
Therefore, our aim is to investigate the possible associations between hyperuricaemia, gout, prescription of allopurinol and renal outcomes in patients with CKD. (edu.au)
Conclusion Hyperuricaemia seemed to be independently associated with faster CKD progression or renal death. (edu.au)
Studies have shown that hyperuricemia plays a major role in the development of CVD and rapid progression of CKD to end-stage renal disease. (smjonline.org)
Early diagnosis and treatment of hyperuricemia in predialysis CKD patients will slow the progression of CKD to end-stage renal disease, reduce cardiovascular morbidity and mortality. (smjonline.org)

We tested this hypothesis in a bi-racial cohort of younger African-American and white men and women.Methods: Data from 5,049 participants at the Coronary Artery Risk Development in Young Adults (CARDIA) cohort baseline (1985 to1986) and follow-up for up to 20 years of individuals without hyperuricemia (defined as a serum urate of 6.8 mg/dL or more) at baseline were utilized. (umn.edu)
We determined associations between race, serum urate and the development of hyperuricemia in sex-specific cross-sectional and longitudinal analyses. (umn.edu)
African-American women developed a significantly increased risk of hyperuricemia when compared to white women (HR = 2.31 (1.34 to 3.99)).Conclusions: Young African-American men and women had lower concentrations of serum urate than whites. (umn.edu)
Gout results from elevated serum urate (SU) levels, or hyperuricemia, and is a globally widespread and increasingly burdensome disease. (researchgate.net)
Age-adjusted analysis revealed a significant association between serum urate level and delta eGFR, with no significant association between gout, treatment with allopurinol and delta eGFR. (edu.au)

Proportion of patients with gout, hyperuricaemia and allopurinol treatment increased with advanced CKD stages. (edu.au)
Febuxostat: a review of its use in the treatment of hyperuricaemia in patients with gout. (qxmd.com)

13. What a systematic review and meta-analysis 0n Hyperuricemia and incident hypertension tells? (cmeindia.in)

Sex Difference in the Associations among Obesity-Related Indices with Hyperuricemia in a Large Taiwanese Population Study. (bvsalud.org)
Although obesity is associated with hyperuricemia , data on sex differences in this association are scarce. (bvsalud.org)
Therefore, this study was conducted to explore sex differences in the correlations among various indices of obesity with hyperuricemia in Taiwan . (bvsalud.org)
In conclusion, obesity -related indices were associated with hyperuricemia in this large Taiwanese study, and sex differences were found in these associations , with stronger associations in women than in men . (bvsalud.org)
Several studies have shown that too little or too much sleep is related to poor health problems such as hyperuricemia, hyperlipidemia, hypertension, type 2 diabetes, obesity, cardiovascular disease, and even mortality. (medicalxpress.com)
There was no significant association between hyperuricemia, obesity, gender and dyslipidemia in this study. (smjonline.org)

Dietary education is important for patients with hyperuricemia. (medscape.com)
Association between Dietary Zinc Intake and Hyperuricemia among Adults in the United States. (qxmd.com)
We aim to explore the associations between dietary zinc intake and hyperuricemia (HU) in United States (US) adults. (qxmd.com)
Therefore, we designed this cross-sectional analysis to assess whether dietary magnesium intake modifies the association of vitamin D and insulin resistance. (frontiersin.org)
Measures to reduce hyperuricemia should be put in place especially lifestyle and dietary modification. (smjonline.org)
Objective To analyze the correlations of hyperuricemia (HU) with dietary vitamin D intake in male youngsters, in order to provide new preventive method to male youngsters with HU. (magtech.com.cn)
Correlation analysis of hyperuricemia with dietary vitamin D intake inmale youngsters[J]. Chinese Journal of Child Health Care, 2021, 29(6): 609-613. (magtech.com.cn)

Hyperuricemia was an independent risk factor for acute MI in the multivariable regression models, with an odds ratio (OR) of 1.11 (95% confidence interval [95% CI] 1.08-1.15, P (natap.org)
In separate analyses, a relationship between gout and the risk of acute MI was evident among those with and without those hyperuricemia. (natap.org)
The American College of Rheumatology (ACR) published guidelines on the treatment and prophylaxis of acute gouty arthritis and the management of hyperuricemia. (medscape.com)

Most patients with asymptomatic hyperuricemia never develop gout or stones. (medscape.com)
Treatment for asymptomatic hyperuricemia carries some risk. (medscape.com)
As a general rule, asymptomatic hyperuricemia should not be treated, though ultrasonographic studies have demonstrated that urate crystal deposition into soft tissues occurs in a minority of patients with asymptomatic hyperuricemia. (medscape.com)

Not all people with hyperuricemia develop gout. (wikipedia.org)

For years, hyperuricemia has been identified with or thought to be the same as gout, but uric acid has now been identified as a marker for a number of metabolic and hemodynamic abnormalities. (medscape.com)
Myogenic hyperuricemia, as a result of the myokinase (adenylate kinase) reaction and the Purine Nucleotide Cycle running when ATP reservoirs in muscle cells are low (ADP>ATP), is a common pathophysiologic feature of glycogenoses such as GSD-III, GSD-V and GSD-VII, as they are metabolic myopathies which impair the ability of ATP (energy) production for the muscle cells to use. (wikipedia.org)
Hyperuricemia (HUA) is an early-onset metabolic disorder. (ijomeh.eu)

Conclusion: Hyperuricemia is associated with an increased risk for incident hypertension, independent of traditional hypertension risk factors. (cmeindia.in)

Recent studies have illuminated the pathophysiology of gout/hyperuricemia and its epidemiology, diagnosis, treatment, and complications. (researchgate.net)

Development of gout - which is a painful, short-term disorder - is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones, another painful disorder. (wikipedia.org)
In the EU, it is indicated in adults for the treatment of chronic hyperuricaemia in conditions where urate deposition has already occurred. (qxmd.com)

Elevated blood lead is significantly correlated with both impaired kidney function and hyperuricemia (although the causal relationship among these correlations is not known). (wikipedia.org)

Among adults in the United States, we found an independent association between vitamin D level and insulin resistance, and this association was modified according to different levels of magnesium intake. (frontiersin.org)
Sexual dimorphism for the association between vitamin D and insulin resistance in Chinese people [J]. Int J Endocrinol, 2018, 2018:1216370. (magtech.com.cn)

Hyperuricemia has been linked with the development of diabetes, gout , kidney , and cardiovascular diseases . (bvsalud.org)
Hyperuricemia has been demonstrated to be a risk factor for cardiovascular diseases. (nih.gov)

Hyperuricemia is most often associated with gout, an increasingly common form of arthritis characterized by severe pain , redness, and tenderness in joints. (medicalxpress.com)
Gout develops when elevated urate levels in the blood (hyperuricemia) lead to the formation of urate crystals in joints, triggering an inflammatory response from the immune system. (medlineplus.gov)

Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. (wikipedia.org)
Foods high in the purines adenine and hypoxanthine may aggravate symptoms of hyperuricemia. (wikipedia.org)
Monitor for signs and symptoms of hyperuricemia, and initiate treatment with urate-lowering drugs as appropriate. (globenewswire.com)

That's because, according to previous studies, hyperuricemia is inversely related to estrogen levels. (medicalxpress.com)

Hyperuricemia may occur because of decreased excretion (underexcretors), increased production (overproducers), or a combination of those two mechanisms. (medscape.com)
Hyperuricemia may be the result of increased production of uric acid, decreased excretion of uric acid, or both increased production and reduced excretion. (wikipedia.org)
Causes of hyperuricemia can be classified into three functional types: increased production of uric acid, decreased excretion of uric acid, and mixed type. (wikipedia.org)
The principal drugs that contribute to hyperuricemia by decreased excretion are the primary antiuricosurics. (wikipedia.org)
Hyperuricemia can result from overproduction, under-excretion of uric acid, or by both processes. (smjonline.org)

These studies point to associations between UA levels and left atrial remodeling and the risk for AF. (medpagetoday.com)
One study from 2015 showed an association between higher magnesium intake and lower blood levels of uric acid, which means it might lower the risk of a painful flare-up. (doctorshealthpress.com)
Although no statement regarding hyperuricemia was included in the Amsterdam Forum on the Care of the Live Kidney Donor published in 2005,(7) given these emerging studies on hyperuricemia for the general population and living donors, the 2017 Kidney Disease Improving Global Outcomes Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors referred to the potential impact of UA levels on living donors. (researchsquare.com)
Normally, male UA levels greater than 7 mg/dL or female UA levels greater than 6 mg/dL are considered to be hyperuricemia (Hao et al. (cmeindia.in)

Further studies are required to identify the causal relationships between sleep recovery and hyperuricemia in postmenopausal women. (medicalxpress.com)
More studies are required to establish causal relationships between these associations. (biomedcentral.com)

[ 1 ] Despite the fact that uric acid was first identified approximately 2 centuries ago, certain pathophysiologic aspects of hyperuricemia are still not clearly understood. (medscape.com)

The observation that longstanding hyperuricemia is associated with chronic tubulointerstitial disease and intrarenal vaso-constriction raised the hypothesis that hyperuricemia might contribute to chronic CSA nephropathy. (ewha.ac.kr)
Missense mutations in UMOD cause tubulointerstitial nephropathy with hyperuricemia , previously named MCKD type 2 or juvenile hyperuricemic nephropathy type 1. (medscape.com)

During longitudinal follow-up, African-American women had a significantly increased risk of developing hyperuricemia when compared with white women, a difference that was not observed in men. (umn.edu)
In an elderly population with cognitive impairment, we investigated the association between serum uric acid (sUA) and serum homocysteine (sHcy), known risk factors for cerebrovascular disease. (mdpi.com)
This study revealed that short sleep duration is associated with an increased risk of hyperuricemia and hypertension. (ndhu.edu.tw)
Besides, the risk of hyperuricemia in females who slept for more than 8 hours was 1.019 times that of those who slept for 7 hours. (ndhu.edu.tw)
A new study suggests that weekend catch-up sleep may minimize the risk of hyperuricemia in postmenopausal women. (medicalxpress.com)
A suggested approach to lowering the risk of hyperuricemia is adequate sleep duration that unfortunately becomes more of a challenge during the postmenopausal phase. (medicalxpress.com)
In this latest study involving nearly 1,900 participants, the researchers hypothesized that weekend catch-up sleep could be a solution to making up for lost sleep during the week and effectively lowering the risk of hyperuricemia in postmenopausal women, who often struggle to get sufficient sleep. (medicalxpress.com)
10) Furthermore, recent clinical studies revealed that hyperuricemia was an independent risk factor for cardiovascular events and the progression of chronic kidney diseases (CKD) in the general population,(19-22) which is also true for patients with CKD and kidney transplant recipients. (researchsquare.com)
Hyperuricemia increased the relative risk of hypertension by approximately 30% in men under 60 and by 2.6-fold in women under 40. (cmeindia.in)
Hyperuricemia has emerged as one of the nontraditional cardiovascular risk factors. (smjonline.org)
Common variants in UMOD have also been demonstrated in large genome-wide association studies (GWAS) to confer independent risk for both hypertension and kidney disease illustrating the shared risk for both phenotypes within this locus (see the GWAS in Nephrology team description for more). (medscape.com)

CSA treated rats developed mild hyperuricemia with arteriolar hyalinosis, tubular injury and striped interstitial fibrosis. (ewha.ac.kr)

Theoretically, alterations in this balance may account for hyperuricemia, although clinically defective elimination accounts for most cases of hyperuricemia. (medscape.com)

The clinical scenarios under which hyperuricemia can be symptomatic are gout, uric acid stones, or uric acid nephropathy. (medscape.com)
Hyperuricemia was more prevalent in younger predialysis CKD subjects and those with hypertensive nephropathy. (smjonline.org)

Hyperuricemia is highly prevalent in young predialysis CKD patients even in the early stages. (smjonline.org)

Finally, enhanced reabsorption of uric acid distal to the site of secretion is the mechanism thought to be responsible for the hyperuricemia observed with diuretic therapy and diabetes insipidus. (medscape.com)
The caricature of the typical patient with hyperuricemia is an obese middle-aged man with hypertension, diabetes mellitus, and hyperlipidemia who is given to excessive drinking. (natap.org)
ANN ARBOR, Mich., June 24, 2023 (GLOBE NEWSWIRE) -- Esperion (NASDAQ: ESPR) announced the results from the pre-specified, primary prevention CLEAR Outcomes subgroup analysis at the 83rd American Diabetes Association (ADA) Scientific Sessions. (ricentral.com)

Introduction There is scant data on the role of hyperuricaemia, gout and allopurinol treatment in chronic kidney disease (CKD). (edu.au)
0.36 mmol/L. Association of delta estimated glomerular filtration rate (eGFR) with gout, allopurinol treatment and hyperuricaemia were analysed. (edu.au)

Hyperuricemia may occur early in treatment and persist throughout treatment, and may lead to the development of gout, especially in patients with a history of gout. (globenewswire.com)

In some studies hyperuricemia is present in 40 to 60% of subjects with untreated hypertension. (cmeindia.in)
State-specific information on SSB intake is limited, and only a few studies have examined associations between behavioral factors and SSB intake among US adults. (cdc.gov)

citation needed] A purine-rich diet is a common but minor cause of hyperuricemia. (wikipedia.org)
Diet alone generally is not sufficient to cause hyperuricemia (see Gout). (wikipedia.org)
Hyperuricemia cosegregating with osteogenesis imperfecta has been shown to be associated with a mutation in GPATCH8 using exome sequencing A ketogenic diet impairs the ability of the kidney to excrete uric acid, due to competition for transport between uric acid and ketones. (wikipedia.org)

Sugar-sweetened soda consumption, hyperuricemia, and kidney disease. (cdc.gov)

8) However, the prognostic significance of hyperuricemia in living donors remains scarce so far. (researchsquare.com)

Multivariable logistic regression analysis was performed to examine the association between zinc intake and HU after adjustment for possible confounders. (qxmd.com)
The association with increased left atrial size persisted after multivariable adjustment. (medpagetoday.com)

Hyperuricemia has been recently identified as a factor of progression of CKD. (biomedcentral.com)
These data suggest that hyperuricaemia is likely the effect and not the cause of CKD or CKD progression. (edu.au)

Our objective was to describe SSB intake (regular soda/fruit drinks) in adults by using a state-specific data source and to examine the associations between SSB intake and sociodemographic and behavioral characteristics. (cdc.gov)

Anatomy2

Diseases10

Chemicals and Drugs18

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Technology, Industry, Agriculture1

Health Care2

Geographicals1

Prevalence11

Uric acid levels4

Blood uric acid1

Gout and hyperuricemia1

Effect of hyperuricemia2

Hypertension and hyperuricemia4

Relationship between hyperuricemia1

Renal11

Serum urate5

Patients with gout2

Systematic review and meta-analysis1

Obesity6

Dietary7

Acute3

Asymptomatic3

Develop gout1

Metabolic3

Conclusion1

Pathophysiology1

Deposition2

Correlations1

Insulin resistance2

Cardiovascular diseases2

Joints2

Symptoms3

Inversely1

Excretion5

Levels4

Causal relationships2

Pathophysiologic1

Tubulointerstitial2

Risk11

Tubular1

Clinically1

Nephropathy2

Stages1

Diabetes3

Allopurinol2

Treatment1

Studies2

Diet3

Consumption1

Scarce1

Multivariable2

Progression2

Intake1