IschemiaPerfusionCardiacElevationReperfusionLate gadolinium enhancementEchocardiographyCoronary SyndromeAtrialPercutaneousSystolicAbnormalitiesArrhythmiasIncidenceSudden deathClinicalInferiorAnginaPatientsAbnormalScarTissueCapillaryIncreasesTroponinDifferencesOnsetCommonlyDetectDiffuseAcute or chronicExtentEvaluateDepressionCongestiveFunctionSymptomEvaluationDeterminationInjuryLong-termSoughtMetabolic
Ischemia7
- We previously demonstrated that chronic pretreatment with a thiazolidinedione peroxisome proliferator-activated receptor (PPAR)-γ activator, troglitazone, improves recovery of left ventricular (LV) function and substrate metabolism after ischemia and reperfusion, without causing arrhythmias. (diabetesjournals.org)
- Acute treatment with troglitazone increases susceptibility to ventricular fibrillation during myocardial ischemia and reperfusion. (diabetesjournals.org)
- In the situation of acute coronary occlusion, the myocardium supplied by the occluded vessel is subject to ischemia and is referred to as the myocardium at risk (MaR). Single photon emission computed tomography has previously been used for quantitative assessment of the MaR. It is, however, associated with considerable logistic challenges for employment in clinical routine. (biomedcentral.com)
- Thereafter, the infarcted area will increase by transmural progression from the endocardium to the epicardium with increasing duration of ischemia, referred to as the wavefront phenomenon[ 11 ]. (biomedcentral.com)
- Evaluation for heritable forms of thrombophilia (eg, prothrombin G20210 and C677T MTHFR gene mutations) and protein C deficiencies should be considered in young patients with myocardial ischemia. (medscape.com)
- 4-7 Angina pectoris is defined as chest discomfort attributed to myocardial ischemia. (uscjournal.com)
- Acute coronary syndrome (ACS) encompasses conditions that include confirmed or suspected myocardial ischemia or myocardial infarction (MI). (lecturio.com)
Perfusion4
- Other applications, such as evaluation of myocardial perfusion and of valvular and ventricular function, are very accurately performed with MRI, but competing modalities, such as single-photon emission computed tomography (SPECT) scanning and echocardiography, are more commonly used in clinical practice. (medscape.com)
- Currently, the most widely used method to determine myocardial perfusion defects is myocardial perfusion single photon emission computed tomography (SPECT). (biomedcentral.com)
- Thus, using myocardial perfusion SPECT for determination of MaR in patients with acute coronary occlusion is a major logistic challenge not possible at many hospitals[ 6 ]. (biomedcentral.com)
- Impaired transmural perfusion of plasma is noted to be involved in the development of necroses in stenotic CA atherosclerotic plaques. (ter-arkhiv.ru)
Cardiac10
- Besides its superiority in determining mass and volumes of the heart, structural imaging of myocardial tissue has become the domain of cardiac MRI. (medscape.com)
- Testing of cardiac enzymes is the standard for identification of myocardial cell death. (medscape.com)
- Consequences depend on degree and location of obstruction and range from unstable angina to non-ST-segment elevation myocardial infarction (NSTEMI), ST-segment elevation myocardial infarction (STEMI), and sudden cardiac death. (msdmanuals.com)
- The results of an EPS facilitate the assessment of complex arrhythmias, elucidate symptoms, evaluate abnormal EKGs, assess the risk of developing arrhythmias in the future, and design treatment options, which may include pharmaceutical therapy or the surgical implantation of a cardiac defibrillator, pacemaker, or a cardiac ablation procedure. (bionapcfa.com)
- Together with Thor Edvardsen, the center director, Haugaa is a principal investigator for center workpackage focusing on risk assessment for sudden cardiac death (SCD) and myocardial function. (ous-research.no)
- She finished her PhD thesis in 2010 which included electromechanical studies in patients with cardiac genetic disorders and patients after myocardial infarction. (ous-research.no)
- Myocardial strain imaging uses speckle-tracking echocardiography to measure tissue deformation through the cardiac cycle. (medscape.com)
- Patients with chronic congestive cardiac failure (CCF) frequently suffer from central sleep apnoea syndrome (CSAS). (ersjournals.com)
- Secondly, torsion is a useful and interesting index of cardiac performance which provides important information on myocardial mechanics that complements standard pump function indices. (biomedcentral.com)
- For PCI in patients with normal baseline troponin values, elevations of cardiac biomarkers above the 99th percentile upper reference limit indicate periprocedural myocardial necrosis. (medscape.com)
Elevation7
- Thirty-seven patients with early reperfused first-time ST-segment elevation myocardial infarction underwent CMR imaging within the first week after percutaneous coronary intervention. (biomedcentral.com)
- STEMI, transmural MI) is myocardial necrosis with ECG changes showing ST-segment elevation that is not quickly reversed by nitroglycerin or showing new left bundle branch block. (msdmanuals.com)
- Detailed data have shown a drop in the hospitalization rates for ST-segment elevation myocardial infarction (STEMI) and a rise in the proportion of hospital admissions for other forms (NSTEMI) in the past decade in both Europe and the United States [ 5 , 6 , 7 ]. (debuglies.com)
- We and others have shown that increases in particulate air pollutant (PM) concentrations in the previous hours and days have been associated with increased risks of myocardial infarction, but little is known about the relationships between air pollution and specific subsets of myocardial infarction, such as ST-elevation myocardial infarction (STEMI) and non ST-elevation myocardial infarction (NSTEMI). (biomedcentral.com)
- ST segment elevation myocardial infarction [STEMI], non-ST segment elevation myocardial infarction [NSTEMI], and unstable angina) to reflect the spectrum of pathophysiologic events occurring. (biomedcentral.com)
- 10-year outcomes after acute ST-elevation myocardial infarction treated with primary percutaneous coronary intervention - single center experience. (kardio.hr)
- Right ventricular involvement in inferior ST-segment elevation myocardial infarction - incidence and significance in mid and long-term follow-up. (kardio.hr)
Reperfusion2
- This study demonstrated that the endocardial extent of infarction as assessed by LGE CMR underestimates MaR in comparison to T2-weighted imaging, especially in patients with early reperfusion and aborted myocardial infarction. (biomedcentral.com)
- Thus, time to reperfusion is thought to limit the transmural infarct progression rather than the endocardial extent of infarction. (biomedcentral.com)
Late gadolinium enhancement1
- The principal utility of CMR and its advantage over echocardiography for cardiomyopathy is its use of late gadolinium enhancement (LGE) , which visualizes myocardial tissue and detects scar, fibrosis, or infiltration. (medscape.com)
Echocardiography2
- REVIEW published: 29 October 2021 doi: 10.3389/fcvm.2021.723542 Doppler Echocardiography Assessment of Coronary Microvascular Function in Patients With Angina and No Obstructive Coronary Artery Disease Jakob Schroder* and Eva Prescott Department of Cardiology, Bispebjerg Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark Edited by: Echocardiographic evaluation is an essential part of the diagnostic work-up in Tim van de Hoef, Academic Medical patients with known or suspected cardiovascular disease. (readkong.com)
- Association with symptoms and prognosis, Doppler Echocardiography comparison with alternative invasive and non-invasive imaging modalities, and possible Assessment of Coronary Microvascular Function in Patients interventions in angina patients with low CFVR were discussed, and key research With Angina and No Obstructive questions were proposed. (readkong.com)
Coronary Syndrome1
- Association of galectin-3 and significant atherosclerotic epicardial artery disease in patients with chronic coronary syndrome. (kardio.hr)
Atrial2
- moral Resonance Spectroscopy: atrial year of Supporting the Fungistatic phosphorus of chronic bodies depressed as metastatic patients, processes or Patients. (siriuspixels.com)
- Clinical outcomes of atrial fibrillation and acute myocardial infarction in long-term follow up. (kardio.hr)
Percutaneous1
- 8. Percutaneous balloon occlusion of post-infarction ventricular septal defect. (prime-cardiology.com)
Systolic2
- Myocardial strain imaging, a reproducible measure of LV systolic function, can identify subclinical LV dysfunction and patterns that suggest specific cardiomyopathies (eg, ischemic cardiomyopathy, amyloidosis, hypertrophic cardiomyopathy, chemotherapy-induced cardiotoxicity). (medscape.com)
- Torsion gives useful additional information about myocardial tissue performance in both systolic and diastolic function. (biomedcentral.com)
Abnormalities1
- Magnetic resonance imaging (MRI) can reveal coronary origins, anatomy, and abnormalities, as well as infarction, in patients with Kawasaki disease. (medscape.com)
Arrhythmias1
- Unstable angina is clinically unstable and often a prelude to myocardial infarction or arrhythmias or, less commonly, to sudden death. (msdmanuals.com)
Incidence2
- A longer hospitalization period, higher incidence of myocardial infarction and higher peak creatine kinase level were observed in patients with a larger ΔK. (biomedcentral.com)
- Alteplase (injection) is a thrombolytic agent that is FDA approved for the treatment of acute myocardial infarction (AMI) in adults for the improvement of ventricular function following AMI , the reduction of the incidence of congestive heart failure , and the reduction of mortality associated with AMI . (wikidoc.org)
Sudden death1
- He also has active studies in understanding the remodeling that occurs in the ventricle in the setting of heart failure and myocardial infarction to create the substrate for sudden death and ventricular tachycardia and fibrillation. (ucsf.edu)
Clinical2
- Current dogma suggest that several genetic polymorphisms of ITGA2B have been associated with a wide variety of clinical events including myocardial infarction (MI) at a young age, stroke and resistance to antiplatelet agents (6-8). (peertechzpublications.com)
- Because 3D TTE is superior to 2D assessment, it is now more widely used in clinical practice. (medscape.com)
Inferior1
- 4. Spontaneous coronary artery dissection in a young man with inferior wall myocardial infarction. (prime-cardiology.com)
Angina2
- The present diagnostic paradigm in patients with angina pectoris is focused on likelihood and subsequent identification of obstructive CAD PATHOPHYSIOLOGIC BASIS (3, 4), but most patients referred for assessment do not fulfill criteria for invasive coronary angiography (ICA), and in the Under resting conditions, the coronary blood flow is kept subset of patients ultimately examined with ICA, many patients, constant at varying coronary pressures. (readkong.com)
- Diagnostic problem in acute infarction and vasospastic angina pectoris. (kardio.hr)
Patients7
- No MaR could be determined by endocardial extent of infarction in two patients with aborted myocardial infarction. (biomedcentral.com)
- A number of laboratory studies are indicated in pediatric patients with myocardial infarction (MI). (medscape.com)
- Therefore, treatment of CSR in combination with "optimised" medical therapy may influence the course of chronic heart failure, quality of life and the survival of patients 10 . (ersjournals.com)
- Patients presenting with acute myocardial infarction and no apparent cardiovascular risk factors: are they wolves in sheep's clothing? (kardio.hr)
- Risk assessment of obstructive sleep apnea in coronary heart disease patients. (kardio.hr)
- Myocardial infarction as a consequence of poor socioeconomic, lifestyle and nutritional characteristics of patients with schizophrenia, bipolar affective disorder and depression. (kardio.hr)
- 15. QT dispersion and viable myocardium in patients with prior myocardial infarction and severe left ventricular dysfunction. (prime-cardiology.com)
Abnormal2
- Used in LGE assessment, gadolinium is an extracellular chelating agent that permeates the interstitial space of both normal and abnormal myocardium . (medscape.com)
- In a patient who presents with chest pain and possible myocardial infarction (MI), an abnormal value is that above the 99th percentile of the healthy population as a cutoff using an assay with acceptable precision. (medscape.com)
Scar1
- CMR identifies areas of increased interstitial space where gadolinium is retained (eg, areas of myocardial infarction, acute edema/inflammation due to capillary leak, myocardial fibrosis/scar, or amyloid protein infiltration). (medscape.com)
Tissue3
- Tissue Doppler imaging (TDI) is an echocardiographic technique that can noninvasively evaluate myocardial contraction and relaxation. (medscape.com)
- T1 and T2 mapping better characterize myocardial tissue by identifying areas of edema (T2), inflammation, and more diffuse fibrosis (T1), which may aid in diagnosing myocarditis without LGE, amyloidosis , hemochromatosis , and Fabry disease . (medscape.com)
- Because ECV defines the proportion of a volume of tissue that consists of extracellular matrix or space between myocytes, it is a marker of myocardial tissue remodeling. (medscape.com)
Capillary1
- Aminaphtone (2-hydroxy-3-methyl-1,4-napthohydroquinone-2-p-aminobenzoate) is normally a artificial molecule derived from four aminobenzoic acids which is currently employed for capillary disorders and for chronic venous insufficiency [18]. (cancercurehere.com)
Increases1
- Previous studies investigating triggering of myocardial infarction by particulate air pollution (PM) concentrations have, in most cases, reported an increased risk of myocardial infarction associated with increases in PM on the same and previous day [ 1 - 9 ]. (biomedcentral.com)
Troponin1
- When measured with older generation assays, elevated troponin levels can be detected 6-12 hours after onset of myocardial injury, peaking at about 24 hours, followed by a gradual decline over several days (up to 2 weeks). (medscape.com)
Differences1
- We hypothesized that this may be due to differences in response to air pollution by myocardial infarction type. (biomedcentral.com)
Onset1
- Recently, using hospital admissions data (without symptom onset time data), we reported that myocardial infarction/PM 2.5 associations may be limited to transmural infarctions [ 6 ]. (biomedcentral.com)
Commonly1
- Myocardial infarction (MI), commonly called heart attack, remains a leading cause of mortality and morbidity worldwide, raising an urgent need for novel therapies. (debuglies.com)
Detect1
- Further, T2* mapping, another parametric imaging approach, can detect and quantify myocardial iron deposition, primarily to assess iron overload cardiomyopathy. (medscape.com)
Diffuse2
- Electrocardiogram in an infant with anomalous origin of the left coronary artery from the pulmonary artery, demonstrating pathologic q waves in leads I and aVL and diffuse ST-T wave changes consistent with an anterolateral infarction. (medscape.com)
- Parametric T1 and T2 mapping sequences can be used for evaluation of diffuse, interstitial myocardial fibrosis that is not detected by LGE imaging. (medscape.com)
Acute or chronic3
- Pyelonephritis can be acute or chronic (which results from persistent or chronic infections). (lecturio.com)
- The symptoms can be acute or chronic, and diagnosis is usually based on radiographic findings, typically a CT pulmonary angiogram. (lecturio.com)
- Infectious agents can cause acute or chronic changes through: (1) direct infiltration of inflammatory cells, (2) action of released toxins or (3) the delayed type immune response. (biomedcentral.com)
Extent3
- Furthermore, it has been suggested that the endocardial extent of infarction as assessed by late gadolinium enhanced (LGE) CMR can also be used to quantify the MaR. Hence, we sought to assess the ability of endocardial extent of infarction by LGE CMR to predict MaR as compared to T2-weighted imaging. (biomedcentral.com)
- The ability of endocardial extent of infarction by LGE CMR to assess MaR was evaluated using T2-weighted imaging as the reference method. (biomedcentral.com)
- The pathophysiological basis for using endocardial extent of infarction as a measure of MaR is that previous experimental studies have shown that the endocardial extent of infarction is established approximately 40 minutes after coronary occlusion[ 11 ]. (biomedcentral.com)
Evaluate1
- Purpose: This review aims to evaluate the role of delta radiomics in the immunotherapy response assessment. (bvsalud.org)
Depression1
- This study investigated whether continuative use of antidepressants (ADs), considered as a proxy of a state of depression, prior to acute myocardial infarction (AMI) is associated with a higher mortality afterwards. (debuglies.com)
Congestive1
- renal: raising ebook zerspantechnik prozesse werkzeuge technologien mit controlled by novel or benign differential, physiological blood or Using from the ventilator of arterial etiology compound, skeletal as plasma assessment or humans-with minerals, of congestive changes, or from mechanical hundreds. (siriuspixels.com)
Function3
- MRI is considered the gold standard in the evaluation of myocardial function. (ecrjournal.com)
- MRI is now considered the gold standard in the evaluation of myocardial function because of its high accuracy as well as inter- and intra-observer reproducibility. (ecrjournal.com)
- Regional myocardial function can be estimated visually in an SSFP sequence, but can be quantified more accurately using myocardial tagging techniques such as spatial modulation of magnetisation. (ecrjournal.com)
Symptom1
- To compare symptom burden, as measured by the MD Anderson Symptom Inventory - Head and Neck (MDASI-HN) (primary patient reported outcome [PRO]), and quality of life, as measured by the Functional Assessment of Cancer Therapy - Head and Neck (FACT-H&N) (secondary PRO), between each experimental arm and the control arm. (ucdavis.edu)
Evaluation1
- Although the formal GRADE (Grading of Recommendations Assessment, Development and Evaluation) system of evidence review with the generation of evidence profiles was not conducted, in making their recommendations the Task Force members took into account the principles of the GRADE system. (springer.com)
Determination1
- Owing to its high-spatial resolution and 3D tomography, CMR provides superior myocardial border definition and volumetric analysis, accurate determination of regional wall thickness and myocardial mass, and sensitive detection of WMA. (medscape.com)
Injury1
- Troponins are released in response to myocardial injury regardless of cause. (medscape.com)
Long-term1
- In contrast, multimorbidity describes someone having two or more long-term (chronic) conditions without any of them holding priority over the others. (wikipedia.org)
Sought1
- Therefore, in order to better understand the relationship between the acute pathophysiologic process of myocardial infarction and increased air pollutant concentrations, we sought to study acute coronary syndromes (i.e. (biomedcentral.com)
Metabolic1
- This key insufficiency may obtain to identify the best heart cancer metabolic, as it will require an gene of chronic aims through which address application varied console may resist an source. (siriuspixels.com)