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  • noninvasive assessment
  • In recent years, it has become increasingly popular to employ spectral analysis of heart rate variability (HRV) as a simple and cost-effective tool for noninvasive assessment of autonomic function.7 The power of the HRV spectrum in the frequency range of 0.15 to 0.4 Hz, referred to as high-frequency power (HFP), is frequently taken to quantify vagal tone. (spotidoc.com)
  • incident
  • Conclusions There is an excess of models predicting incident CVD in the general population. (bmj.com)
  • preclinical
  • Conclusions- Magneto-fluorescent nanoparticle CMR permitted effective visualization of myocardial inflammatory cellular infiltrates and distinction of the extent of inflammation compared with conventional CMR in a preclinical model of EAM. (ahajournals.org)
  • INTRODUCTION: Despite effective in vitro preclinical strategies to identify cardiovascular (CV) liabilities, there remains a need for early functional assessment prior to complex in vivo mammalian models. (exeter.ac.uk)
  • pathways
  • With the recent advances in transgenic and gene-targeting approaches, engineered mice have been used as a powerful tool to identify and validate genes and cellular pathways underlying different cardiovascular phenotypes such as hypertrophic (6) and dilated (7) cardiomyopathies, but the lack of standardized and reproducible exercise training protocols has limited the understanding of this complex biological process. (scielo.br)
  • Therefore, in this study, we used a neural computational model that includes both monosynaptic and multisynaptic corticospinal pathways interacting with a propriospinal neuronal network. (readbyqxmd.com)
  • HOMA2
  • HOMA2-%B is a computer model that uses fasting plasma insulin and glucose concentrations to estimate steady-state beta cell function (%B) as a percentage of a normal reference population (normal young adults). (clinicaltrials.gov)
  • predictors
  • Analysis from the largest prospective study of adolescent bariatric surgery outcomes offers important insights regarding previously unknown predictors of change in cardiovascular risk factors, which may promote future refinements in patient selection and the optimization of the timing of surgery. (aappublications.org)
  • To address these knowledge gaps, data from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study were used to examine predictors of change in cardiovascular disease (CVD) risk. (aappublications.org)
  • Rather than developing yet another similar CVD risk prediction model, in this era of large datasets, future research should focus on externally validating and comparing head-to-head promising CVD risk models that already exist, on tailoring or even combining these models to local settings, and investigating whether these models can be extended by addition of new predictors. (bmj.com)
  • Methods
  • The algorithms are extended to model multi-dimensional non-conservative hyperbolic systems (for example: shallow water equations including tsunamis, granular flow and plasma physics flows) using path conservation methods and Riemann solvers. (ams.org)
  • METHODS: Non-invasive video analysis of the heart and dorsal aorta of anaesthetized and agarose-embedded larval ZF was used to measure multiple cardiovascular endpoints, simultaneously, following treatment with a range of functional modulators of CV physiology. (exeter.ac.uk)
  • More recent work involves sensitivity analysis for multilevel models and Bayesian computational methods. (nyu.edu)
  • QRISK
  • The latest model, QRISK, was developed using a primary care database and our work has reinforced the current debate over analysis methodology in such studies. (uea.ac.uk)
  • Multivariable
  • Multivariable models also examined the association between attributable CVD risk and appropriate self-management behaviour. (cfp.ca)
  • Eligibility criteria for study selection Studies describing the development or external validation of a multivariable model for predicting CVD risk in the general population. (bmj.com)
  • measures
  • Consequently, we developed a novel larval Zf model capable of simultaneous quantification of chronotropic, inotropic and arrhythmic effects, alongside measures of blood flow and vessel diameter. (exeter.ac.uk)
  • Apart from increased mean heart rate in OSA, there were no significant differences in other summary and spectral measures of cardiovascular variability. (spotidoc.com)
  • Model performance was heterogeneous and measures such as discrimination and calibration were reported for only 65% and 58% of the external validations, respectively. (bmj.com)
  • cardiac
  • The model was extended to incorporate time-varying parameter changes for analysis of the data collected during cold face stimulation: cardiac output gain increased in controls but remained unchanged in OSAS. (spotidoc.com)
  • Strain analysis from echocardiography confirms the hypothesis of the center point trajectory model from cardiac MR. (biomedcentral.com)
  • There are three well-known models to assist with maternal cardiac risk stratification. (acc.org)
  • algorithms
  • Better numerical algorithms based on mathematical insights will result in better simulation models for more accurate predictions. (ams.org)
  • obstructive
  • Model-based assessment of cardiovascular autonomic control in children with obstructive sleep apnea. (spotidoc.com)
  • ALTHOUGH OBSTRUCTIVE SLEEP APNEA SYNDROME (OSAS) OCCURS QUITE FREQUENTLY IN THE PEDIATRIC POPULATION, WITH A PREVALENCE RATE OF 1 TO 3% in preschool-aged children,1 the cardiovascular consequences of OSAS in children have been less extensively studied, compared with the adult form of sleep-disordered breathing. (spotidoc.com)
  • Autonomic function in patients with obstructive sleep apnea (OSA) has been evaluated using cardiovascular reflex tests, which involve subject cooperation (controlled breathing, abrupt change in posture from supine to standing, Valsava maneuver and sustained handgrip) . (spotidoc.com)
  • Simulation
  • Systems oncology simulation, using mathematical models designed to predict tumour growth and treatment response, provides a powerful tool for analysis and optimization of combined treatments. (readbyqxmd.com)
  • development
  • Use my knowledge and expertise to support research colleagues in the development of other novel zebrafish assays for the assessment of human safety. (exeter.ac.uk)
  • Dr. Scott's research involves the development of statistical models for longitudinal data. (nyu.edu)
  • novel
  • This novel wall motion assessment tool correlates well with 2D echocardiographic strain maps as the reference standard. (biomedcentral.com)
  • Supporting a new research collaboration to identify novel complimentary techniques using the Zebrafish model, to extend its application and to encourage wider acceptance and usage within industry. (exeter.ac.uk)
  • dynamics
  • The dynamics of space weather is modeled by the magnetohydrodynamics (MFD) equations that capture the interaction between magnetic fields and moving, conducting fluids. (ams.org)
  • risk factors
  • Many of the risk factors predisposing people to CVD are known, and there are a number of survival models to identify those who could benefit from preventive treatment. (uea.ac.uk)
  • Increased levels of the nontraditional cardiovascular disease (CVD) risk factors C-reactive protein (CRP), plasminogen activator-1 (PAI-1), and fibrinogen have been associated with increased CVD in the general population ( 1 - 4 ). (diabetesjournals.org)
  • studies
  • Dr. Scott teaches Multi-Level Models: Growth Curves / Nested Data (APSTA-GE.2040/41/42), Practicum in Statistical Computing (APSTA-GE.2352) and Supervised and Unsupervised Machine Learning (APSTA-GE.2011), He serves as co-director with Lisa Stulberg of the Interdepartmental Research Studies (IDRS) program. (nyu.edu)
  • The usefulness of most of the models remains unclear owing to methodological shortcomings, incomplete presentation, and lack of external validation and model impact studies. (bmj.com)
  • examine
  • Using a latent variable approach, he developed a new class of covariance models for such data, and has used them to examine trends in wage inequality. (nyu.edu)
  • In the educational setting, such models examine the influence of the entire pathway (e.g., the timing of educational and employment spells and interruptions to these) on an outcome measure such as wages or degree completion. (nyu.edu)