Assays in high throughput. Medical search. Frequent questions

However, plate readers, while capable of providing high-throughput, can only give an average of the fluorescence (and thus cell viability) of an entire well, but not at the single cell level. (technologynetworks.com)
To characterize the enzymatic activity of SARS-CoV-2 M pro and to carry out high-throughput screening of inhibitors, we developed a fluorescence resonance energy transfer assay. (nature.com)
They then use fluorescence-based assays to study protein function. (biologists.com)
We have developed a novel assay for immunoprecipitation, termed FLuorescence IP (FLIP) that is quick, reliable, easy to perform and scalable because it does not rely on immunoblotting analysis. (biomedcentral.com)
Developing magnetic barcode bead fluorescence assay for high throughput analyzing humoral responses against multiple SARS-CoV-2 variants. (bvsalud.org)
To better analyze the antibody levels against SARS-CoV-2 and its variants in vaccinated or infected subjects, we developed a multiplex detection named Barcode Bead Fluorescence (BBF) assay. (bvsalud.org)

OBJECTIVES: We tested whether mechanistically based screening assays can rapidly provide information on the potential for compounds to affect key enzymes and receptor targets, thus identifying those compounds requiring further in-depth analysis. (cdc.gov)

ELISA (Enzyme-linked Immunosorbent Assay) is one of the most popular quantitative methods to detect a target antigen such as toxin or foreign substance within a sample. (moleculardevices.com)
Here we present a cell-free quantitative neutralization assay based on the competitive inhibition of trimeric SARS-CoV-2 Spike protein binding to the angiotensin converting enzyme 2 (ACE2) viral receptor. (medrxiv.org)
Bioconductor includes packages for analysis of diverse areas of high-throughput assays such as flow cytometry, quantitative real-time PCR, mass spectrometry, proteomics and other cell-based data. (riken.jp)
Prot ein display on a Ma ssively- P aralleled Array) that combines sequencing-by-synthesis with protein function assays to enable quantitative protein function assays with a massively high throughput. (biologists.com)
This reactivity of chemicals to cutaneous the peptide reactivity assay ( 10 ), quantitative LC-MS was proteins is the basis for most, if not all, current nonanimal- exploited by Natsch et al. (cdc.gov)

The ideal whole genome methylation (methylome) assay should be accurate, affordable, high-throughput and agnostic with respect to genomic features. (diagenode.com)
Shaping the nebulous enhancer in the era of high-throughput assays and genome editing. (gersteinlab.org)
ATAC-seq is a high-throughput sequencing method for analyzing genome-wide chromatin accessibility, which is essential for understanding the global epigenetic control of gene expression. (novogene.com)
and a fluorescent microscopy setup enabling high throughput low cost whole genome analysis. (wikipedia.org)
Results from analytical studies showed that the Xpert MTB/RIF assay has analytic sensitivity of five genome copies of purified DNA, and 131 cfu/ml of M. tuberculosis spiked into sputum. (bvsalud.org)

Unfortunately, such devices do not allow for high throughput analysis due to the manual effort involved in operating the valving mechanisms. (justia.com)
Our setup employs fluorescent microplate readers that allow for high throughput and replication. (biorxiv.org)

Altogether, our characterizations of this new methodology show that FLIP is an appealing and reliable tool for any application of high-throughput IP. (biomedcentral.com)
Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. (cdc.gov)

Through a combination of structure-based virtual and high-throughput screening, we assayed more than 10,000 compounds-including approved drugs, drug candidates in clinical trials and other pharmacologically active compounds-as inhibitors of M pro . (nature.com)
Identification of small-molecule inhibitors targeting LH2 activity requires a robust and suitable assay system, which is currently lacking. (uky.edu)
This newly developed LH assay is robust, suitable for high-throughput screening, and able to identify potent specific inhibitors of LH2. (uky.edu)
Hence, our novel assay will be a useful tool for high-throughput screening for novel exonuclease inhibitors that may interfere with DNA replication or DNA maintenance. (edu.sa)

Assays with high sensitivity, specificity, and durable antibody detection are ideal for serosurveillance, but assays demonstrating waning reactivity are appropriate for other applications, including correlation with neutralizing activity and detection of anamnestic boosting by reinfections. (cdc.gov)
More than 85 SARS-CoV-2 antibody assays had received US Food and Drug Administration Emergency Use Authorization as of August 19, 2021, ranging from point-of-care tests to fully automated high-throughput platforms ( 1 ). (cdc.gov)
In this informational webinar, Dr. Dmitry Kuksin, Nexcelom Senior Scientist, examines specific virology related assays such as plaque and foci formation, as well as antibody neutralization. (nexcelom.com)
In conclusion, we have developed an assay that has proven its clinical relevance in the large-scale evaluation of effective neutralizing antibody responses to VOC after natural infection and that can be applied to the characterization of vaccine-induced antibody responses and of the potency of human monoclonal antibodies. (medrxiv.org)
To test the technology with protein binding assays, the authors utilised the well-characterised FLAG peptide/M2 antibody system. (biologists.com)
IP and ChIP are both inexpensive and highly informative, relying on a specific antibody to selectively bind to the target epitope with high affinity [ 5 ]. (biomedcentral.com)
We also found that COVID-19 patients showed higher antibody levels against spike beads from wild-type, alpha, beta, and delta . (bvsalud.org)
Presented here is a novel approach of antibody detection using bead-based immunoassay that involves incubating all assay reagents concurrently overnight. (cdc.gov)
This overnight incubation protocol has the potential to be deployed for large-scale malaria serosurveys for the high-throughput and timely collection of antibody data, particularly for malaria seroprevalence estimates. (cdc.gov)

Laboratory automation workflows can help with providing walkaway time, increasing throughput, effectiveness and efficiency of the assay procedure, and reproducibility. (moleculardevices.com)

Of these, single cell RT-qPCR provides combined advantages of sensitivity, specificity, and dynamic range, but is limited by low throughput, high reagent cost, and difficulties in accurately measuring low abundance transcripts (6). (justia.com)
Although these systems provide a high-throughput qPCR readout, they do not address the front end sample preparation and require single cell isolation by FACS or micropipette followed by off-chip processing and pre-amplification of starting template prior to analysis. (justia.com)

The results from this prevali- the field of cancer biomarkers (11-13), and that approach was dation study showed that patients could be classified into high- adopted here to define predictive serum biomarkers associated versus low-risk groups for developing metastatic breast cancer with tumor relapse in breast cancer patients. (lu.se)

Our SARS-CoV-2 Antigen assay features antibodies that maximize variant detection, including the Omicron and Delta variants. (siemens-healthineers.com)
By combining this binding reaction with a high molecular weight entity such as a bead, a bacterial cell or a meshwork of secondary antibodies, it is possible to isolate the protein of interest and its binding partner(s) from all the other cellular components in a microfuge tube [ 6 ]. (biomedcentral.com)
Until now the standard procedure to validate antibodies for IP couples the IP assay to immunoblotting (IP/IB), a procedure that is challenging to scale to high-throughput analysis [ 10 ]. (biomedcentral.com)
Subjects with two doses of mRNA-1273 exhibited the highest level of antibodies against all spike variants compared to two doses of AZD1222 and unvaccinated. (bvsalud.org)
Samples were analysed using bead-based multiplex assays for IgG antibodies for six Plasmodium antigens: four human malaria species-specific merozoite surface protein-1 19kD antigens (MSP-1) and Apical Membrane Antigen-1 (AMA-1) for Plasmodium falciparum and Plasmodium vivax. (cdc.gov)

This high-throughput method matches the performance of the gold standard live virus infectious assay, as verified with a panel of 206 seropositive donors with varying degrees of infection severity and virus-specific IgG titers, achieving 96.7% sensitivity and 100% specificity. (medrxiv.org)
Davin M. Henderson (Colorado State University) and Carl Peters (BMG LABTECH) talked about how to optimize sensitivity and specifity in the RT- QUiC assay using BMG LABTECH plate readers. (news-medical.net)
We show here that FLIP displays similar sensitivity to the standard IP/IB procedure but is amenable to high-throughput analysis. (biomedcentral.com)

By developing image-based high content screening methods to estimate efficacy, potency and early detection of off-target effects of potential drugs, they aim to contribute to the acceleration of the drug discovery process. (wikipedia.org)

We show that our assay is applicable to different eukaryotic and bacterial exonucleases acting on both 3′ and 5′ DNA ends over a wide range of protein activities and suitable for a high-throughput inhibitor screening campaign. (edu.sa)
RESULTS: All the assays have high Z' values, indicating good discrimination among compounds in a reliable fashion, and thus are suitable for HTS assays. (cdc.gov)

We employed the X-ray crystal structure of the PPARγ subtype complexed with the potent small molecule agonist GI262570 (farglitazar) to design and synthesize a novel fluorescent and high-affinity probe for homogeneous and high-throughput fluorescent polarization (FP) assays. (psu.edu)
This fluorescent PPARγ probe enables high-throughput and homogenous FP assays for the identification of novel endogenous and exogenous PPARγ ligands, and this rational ligand design approach may be applied to other therapeutically important members of the nuclear hormone receptor superfamily. (psu.edu)
For enzymatic catalysis assays, the authors also tested their technology on the SNAP-tag protein modification, which can be fused to proteins and subsequently tagged with a ligand, such as a fluorescent dye. (biologists.com)
Here, we present a simple and versatile real-time exonuclease assay based on 2-aminopurine, an intrinsically fluorescent nucleotide that is quenched by neighboring bases when embedded in DNA. (edu.sa)

Using assays and algorithms that detect mild or asymptomatic infections is critical for accurately estimating cumulative incidence, and case-to-infection and death-to-infection ratios. (cdc.gov)
MARLBOROUGH, Mass.--(BUSINESS WIRE)-- Hologic, Inc. (Nasdaq: HOLX) announced today that it plans to launch a new Aptima® molecular assay to detect the SARS-CoV-2 virus that will run on its market-leading Panther® system. (hologic.com)
Scientists use high-dimensional measurement assays to detect and prioritize regions of strong signal in spatially organized domain. (huji.ac.il)

Serosurveillance should be conducted with representative population sampling using well-characterized serologic assays selected on the basis of their performance characteristics and optimized algorithms. (cdc.gov)
Limited head-to-head evaluation data are available for high-throughput SARS-CoV-2 serologic assays, and few large-scale studies have focused on performance for serosurveillance applications. (cdc.gov)

Rapid, high-throughput IgG quantification assay. (valitacell.com)
To facilitate the rapid discovery of antiviral compounds with clinical potential, we developed a strategy that combines structure-assisted drug design, virtual drug screening and high-throughput screening to repurpose existing drugs to target SARS-CoV-2 M pro . (nature.com)
We are proud to be able to support your research by generating high-quality, publication-ready data in a rapid time-frame. (novogene.com)
The continuous mutation of SARS-CoV-2 highlights the need for rapid, cost -effective, and high-throughput detection methods . (bvsalud.org)
Rapid methods of measuring the effects of an agent in a biological or chemical assay. (bvsalud.org)

This high-throughput strategy with good practicability can be easily extended to other protein analytes, providing a powerful protocol for protein analysis and clinical diagnosis. (rsc.org)
AutoMeDIP-seq offers a competitive approach to high-throughput methylome analysis of medium to large cohorts. (diagenode.com)
The following provide a brief overview of packages useful for analysis of high-throughput assays. (riken.jp)
This commitment to high-quality data is essential for the correctness, comprehensiveness, and credibility of bioinformatics analysis. (novogene.com)
The standard assay couples IP to immunoblotting (IP/IB), a procedure severely limited as it is not easily scaled for high-throughput analysis. (biomedcentral.com)
The immunoprecipitation assay (IP) is an important tool used in academic and industrial research labs for applications such as targeted protein purification, protein concentration, analysis of protein-protein interactions, identification/analysis of protein complexes and analysis of protein/DNA interactions using chromatin IP (ChIP). (biomedcentral.com)

antispike and total Ig assays demonstrated more stable longitudinal reactivity than antinucleocapsid and IgG assays. (cdc.gov)
A kinetic spectrophotometric assay involving the reactivity of electrophilic sensitizers to nitrobenzenethiol was evaluated. (cdc.gov)
9 ) with the determination of the RC50 value being the marker reactivity of test chemicals as end point toxicology assays have of the potency of a chemical. (cdc.gov)

After co-culture, the completed assays are scored for visual phenotypes, such as growth or inhibition. (nih.gov)
In the currently available test systems for migration inhibition of NCC (MINC), the manual generation of a cell-free space results in extreme operator dependencies, and limits throughput. (altex.org)

This work integrates target-induced DNA assembly and cleavage on a DNA chip to design a versatile imaging strategy as an assay for multiple proteins. (rsc.org)
From sequence to function: Current Illumina high-throughput sequencing technology adapted to carry out functional screening on a huge variety of proteins. (biologists.com)
For example, RNA-Seq enables the study of gene expression changes, Hi-C considers chromatin architecture and ChIP-seq examines binding of DNA-binding proteins. (biologists.com)
Despite this, drug discovery for AQPs has made little progress due to a lack of reproducible high-throughput assays and difficulties with the druggability of AQP proteins. (lu.se)

To this end, the methylated DNA immunoprecipitation (MeDIP) assay provides a good balance of these criteria. (diagenode.com)
The immunoprecipitation (IP) assay is a valuable molecular biology tool applied across a breadth of fields. (biomedcentral.com)

Whether you are performing biochemical assays such as ELISA , DNA/RNA quantitation , MTT cytotoxicity , or binding/affinity or cell-based assays such as CRISPR, viral titer, protein expression , bacterial growth, or cell signaling , Molecular Devices microplate readers have empowered life science researchers to advance discovery and produce high quality, reliable data. (moleculardevices.com)
The NIH Molecular Libraries Roadmap Initiative wishes to solicit HTS assay applications from the scientific community from investigators who have the interest and capability to work with the Molecular Libraries Probe Production Centers Network (MLPCN) in support of chemical probe development. (nih.gov)
This initiative is one of the integrated components of the NIH Molecular Libraries Roadmap initiative that offers biomedical researchers access to large-scale automated high throughput screening (HTS) centers in the MLPCN, diverse compound libraries in the Small Molecule Repository (MLSMR) and information on biological activities of small molecules in the PubChem BioAssay public database. (nih.gov)
Combining significant manufacturing capacity for the new test with the world's largest installed base of high-throughput molecular instruments is expected to dramatically increase testing capabilities for the novel coronavirus. (hologic.com)
The Aptima SARS-CoV-2 assay runs on the Panther system, a fully automated, high-throughput molecular diagnostic platform that is widely used around the world, with more than 1,800 systems installed in 60 countries. (hologic.com)
This protocol describes a high-throughput automated and high-content imaging approach to screen siRNA molecular libraries in HeLa cervical cancer cells in 96-well format. (ox.ac.uk)
Comprehensive molecular, cellular and systemic-level assays all support a high level of selectivity. (nature.com)
We do so by demonstrating selectivity across comprehensive molecular, cellular, and systemic assays. (nature.com)
FIND) has partnered with Cepheid, Inc. (Sunnyvale, CA) and the University of Medicine and Dentistry of New Jersey (UMDNJ, Newark, NY) to develop a TB-specific automated, cartridge-based nucleic amplification assay (Xpert MTB/RIF) based on the GeneXpert multi-disease platform, currently unique in its simplification of molecular testing with fully integrated and automated sample preparation, amplification and detection required for real-time polymerase chain reaction. (bvsalud.org)

By increasing the scale and scope of organoid experiments, this automated assay complements other patient-derived models and will expedite preclinical testing of new treatments for prostate cancer. (edu.au)

In this study, we combined epigenomics and transcription factor binding along with high-through-put enhancer assay and 4C-seq to prioritize an enhancer element located 120 kb upstream of the Ikzf1 gene. (hal.science)
The HTS assay approach is very useful to quickly identify potentially hazardous compounds and to prioritize them for further in-depth studies. (cdc.gov)

Illumina high-throughput sequencing technologies have been widely utilised to tackle many biological problems. (biologists.com)
As the position of the clusters remain the same from the initial Illumina MiSeq to the final functional assays, DNA sequence, which determines protein sequence, can be directly correlated with protein function. (biologists.com)
The Swiss-based company invented and developed novel high throughput DNA sequencing technologies currently owned by Illumina. (wikipedia.org)

Once the assay runs its course, the final absorbance readout will take place on a SpectraMax® iD5 Multi-Mode Microplate Reader. (moleculardevices.com)

Using an automated heat sealer, a sealing film will be placed on the assay plate to prevent evaporation during incubation. (moleculardevices.com)
After incubation, the assay plate is transferred to the seal-peeler to remove the seal from the assay plate and transferred to washing. (moleculardevices.com)
CONCLUSIONS: When using the MBA for IgG detection, overnight incubation for the test sample and all assay reagents greatly minimized hands-on time for laboratory staff. (cdc.gov)

By implementing camera-based widefield imaging for both cell and feature detection, the throughput of the imaging platform could be considerably increased compared to an approach based solely on laser scanning. (uni-goettingen.de)
When compared to a standard multi-step assay, this OneStep assay amplified the assay signal for IgG detection for all 8 malaria antigens. (cdc.gov)
The greatest increases in assay signal were seen at the low- and mid-range IgG titers and were indicative of an enhancement in the analyte detection, not simply an increase in the background signal of the assay. (cdc.gov)

These packages provide data structures and algorithms for cell-based high-throughput screens (HTS). (riken.jp)

In particular, the invention relates to microfluidic devices and their uses and methods for assaying cells. (justia.com)
Robust automated microscopy techniques and streamlined acquisition schemes will be key to increase the throughput of super-resolution methods to meet the requirements for industrial applications, e.g., in pharmaceutical drug screenings. (uni-goettingen.de)
The current academic research of his laboratory focuses on innovative high throughput screening methods and technologies for efficient early drug discovery processes enabling more specific and safer molecules as therapeutic agents, this includes drug repurposing strategies for application in various therapeutic areas. (wikipedia.org)
His research also targets the development of efficient methods for drug screening such as highly informative assays. (wikipedia.org)
METHODS: A library of 176 synthetic chemicals was prepared and examined in a high-throughput screening (HTS) manner using nine enzyme-based and five receptor-based bioassays. (cdc.gov)

Profiling serum samples from 59 hospitalized COVID-19 patients, we found that although most had high activity against the 2019-nCoV Spike and to a lesser extent the B.1.1.7 variant, only 58% could efficiently neutralize a Spike derivative containing mutations present in the B.1.351 variant. (medrxiv.org)

We conducted a multilaboratory evaluation of 21 commercial high-throughput SARS-CoV-2 serologic assays using blinded panels of 1,000 highly characterized specimens. (cdc.gov)

The peptide depletion assay developed skin sensitization perspective, understanding and predicting early by Gerberick et al. (cdc.gov)

Our Quantum technology is currently applied in the field of biologics and powers products such as ValitaTiter , one of the fastest and more robust high throughput IgG quantification assays on the market. (valitacell.com)

By adopting this approach, it is possible to measure growth of several bacterial strains simultaneously in high temporal resolution and in a high throughput manner. (biorxiv.org)

When interrupted during a blood meal, Chrysops flies have been known to make new lacerations to continue to feed from the same host owing to the female's high blood demand for reproductive purposes. (medscape.com)
Due to the high demand for today's COCA call, we ask that you access the call in a group format if possible. (cdc.gov)

Upon studying the mutant affinity landscapes, the authors note that they largely recapitulate the expected consensus sequence (DYKxxDxx), and even find a "superFLAG" sequence that has a LoD 7.9x lower (meaning higher binding affinity) than that of the wild-type FLAG. (biologists.com)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serosurveys can estimate cumulative incidence for monitoring epidemics, requiring assessment of serologic assays to inform testing algorithm development and interpretation of results. (cdc.gov)
Here we describe the results of a programme that aimed to rapidly discover lead compounds for clinical use, by combining structure-assisted drug design, virtual drug screening and high-throughput screening. (nature.com)
The general approach taken by the document is primarily to provide guidance on how test results might be interpreted based on the outcome of standardised assays. (oecd.org)
While the data obtained is of high quality, the approach is insufficient to keep pace with candidate identification and therefore results in biases introduced during the selection of candidates for validation. (mdpi.com)
Xpert MTB/RIF detects M. tuberculosis as well as rifampicin resistance-conferring mutations directly from sputum, in an assay providing results within two hours. (bvsalud.org)

Through its funding of the MLPCN, NIH will support the costs of assay automation, screening and optimization chemistry. (nih.gov)
Overall, this study developed the BBF assay for analyzing humoral immune responses , which has the advantages of robustness, automation , scalability, and cost - effectiveness . (bvsalud.org)
The assay usually involves some form of automation or a way to conduct multiple assays at the same time using sample arrays. (bvsalud.org)

The assay is easy to set up and the range of potential analytes is vast, but the assay procedure is time consuming and labor intensive. (moleculardevices.com)

High-throughput single cell measurement technologies are therefore of interest and have broad applications in clinical and research settings. (justia.com)
In addition, as a part of a related study, sNfL measurement will be performed in spiked control samples and in a subset of participants (100 HC and 100 MS participants) with calculation of intra- and inter-assay coefficient of variation. (cdc.gov)

Seroprevalence estimates were generally similar for this sample Haitian population for all antigens regardless of serum or DBS sample type or assay protocol used. (cdc.gov)

To date, most high-throughput cell viability assays have been performed using plate readers, due to their ease of use and the option to process entire plates very quickly. (technologynetworks.com)
The devices may further include auxiliary chambers integrated with the cell capture chamber for subsequent processing and assaying of the contents of a captured cell. (justia.com)
One of these compounds (ebselen) also exhibited promising antiviral activity in cell-based assays. (nature.com)
The colony formation assay is the gold-standard technique to assess cell viability after treatment with cytotoxic reagents, ionizing radiation, and cytotoxic combinatorial treatments. (ox.ac.uk)
ER stress/UPR (Grp78 and CHOP) and autophagy (LC3B II) markers were assayed by immunoblotting, while ATP levels were measured using the CellTiter-Glo Luminescent Cell Viability Assay. (moonphase2018.com)
To determine whether perturbation of either or both pathways leads to activation of autophagy, ATP levels and ER stress/UPR, markers were assayed in three different human cancer cell lines, i.e., 1420 (pancreatic cancer), MDA-MB-435 (melanoma) [29] and SKBR3 (breast cancer). (moonphase2018.com)
This microwell-based circular migration zone NCC function assay (cMINC) was further optimized for tox-icological testing of human pluripotent stem cell (hPSC)-derived NCCs. (altex.org)
Processes that drive the development of increased cell motility represent high-value therapeutic targets. (nature.com)
We hypothesized that we could use them to identify novel and selective sites that regulate cancer cell motility and that such sites would constitute high-value therapeutic targets. (nature.com)

Whole-animal toxicologic studies cannot yield the necessary throughput in a cost-effective fashion, leading to a critical need for a faster and more cost-effective toxicologic evaluation of xenobiotics. (cdc.gov)

Assay performance must be evaluated in context of intended use, particularly in the context of widespread vaccination and circulation of SARS-CoV-2 variants. (cdc.gov)
Because of their increased risk to public health, Siemens Healthineers is committed to the continuous monitoring of emerging variants and conducting evaluations to help ensure that our assays remain effective at detecting them. (siemens-healthineers.com)
In contrast, a powerful assay makes it possible to extend the number of investigated variants and thus to increase the likelihood to find an improved mutant. (elsevierpure.com)

High capacity: Industry-leading turnaround time. (novogene.com)

Using our assay, we discover a novel inhibitor of the Mycobacterium tuberculosis PHP-exonuclease that is part of the replicative DNA polymerase DnaE1. (edu.sa)

This paper presents a protocol for co-culture interaction assays that are inexpensive, scalable to large sample numbers, and easily adaptable to numerous experimental designs. (nih.gov)
All sera and DBS samples were assayed by MBA using a standard immunoassay protocol with multiple steps, as well a protocol where sample and all reagents were incubated together overnight-termed here the OneStep assay. (cdc.gov)
Enhanced IgG signal was observed with the OneStep assay for all 8 malaria antigens employed in this study, and seroprevalence estimates for this sample population were similar regardless of assay protocol used. (cdc.gov)

She has leadership positions in national efforts to apply computational approaches to chemical safety decisions and has been instrumental in establishing guidelines for assay validation. (cdc.gov)

Plate-based assays form the cornerstone of many laboratory research programs. (moleculardevices.com)
Next week, Hologic expects to begin distributing a Research Use Only (RUO) version of its Aptima SARS-CoV-2 test to hospital, public health and reference laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) to perform high complexity tests. (hologic.com)

Additionally, automated data collection and data tracking reduce human error, assuring that the data is of a higher quality. (moleculardevices.com)
To guarantee the accuracy and reliability of sequencing data, Novogene audits every experimental step through quality control, fundamentally ensuring high-quality data output from sampling to the final data report. (novogene.com)
CONCLUSIONS: Considering the need to rapidly screen tens of thousands of anthropogenic compounds, our study shows the feasibility of using combined HTS assays as a novel approach toward obtaining toxicologic data on numerous biological end points. (cdc.gov)
In addition to study samples, low, medium, and high concentration quality control (QC) samples were run each 8-hour shift as well as additional replicate samples to ensure accuracy and reliability of the derived data. (cdc.gov)
In our OriLAB facility, we can measure the bird's position for several days at high frequency with a throughput of half a million data points per day! (lu.se)

Also next week, Hologic plans to apply for Emergency Use Authorization (EUA) for the Aptima SARS-CoV-2 assay from the U.S. Food and Drug Administration. (hologic.com)

Anatomy7

Organisms9

Diseases1

Chemicals and Drugs47

Analytical, Diagnostic and Therapeutic Techniques and Equipment99

Phenomena and Processes57

Disciplines and Occupations19

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture13

Information Science29

Health Care11

Fluorescence6

Screening Assays1

Quantitative5

Genome5

Allow for high throughput2

Application of high-throughput2

Inhibitors4

Antibody9

Workflows1

QPCR2

Biomarkers1

Antibodies5

Sensitivity3

Efficacy1

Suitable2

Fluorescent4

Detect3

Serosurveillance2

Rapid5

Analysis6

Reactivity3

Inhibition2

Proteins4

Immunoprecipitation2

Molecular9

Organoid1

Prioritize2

Illumina3

Readout1

Incubation3

Detection3

Algorithms1

Methods5

20191

1,0001

Peptide1

Robust1

Bacterial1

Demand2

Affinity1

Results5

Automation3

Analytes1

Measurement2

Serum1

Cell9

Faster1

Variants3

Time1

Inhibitor1

Protocol3

Validation1

Laboratory2

Data5

Drug1